A large study found that people with hypertension or diabetes often lack a simple urine test for protein in the urine, despite being at high risk of chronic kidney disease. The researchers suggest widening albuminuria testing to detect early chronic kidney diseases and emphasize the importance of treatment.
A novel method for imaging vibrations and movements of atoms in catalysts has been developed by a collaboration of internationally leading researchers. The new analytical method reveals a dynamic behavior of the atoms, contrary to the long-held expectation that atoms in nanoparticles are static during observations.
Researchers found a sequential-combinatorial regimen boosts treatment efficacy for aggressive cancers by re-energizing T cells and suppressing tumor growth. The approach offers realistic chances to improve patient survival.
Researchers developed a new method to map supramolecular chirality in insect wings using microscopic vibrational circular dichroism (VCD). The technique revealed segregated microdomains of proteins with different secondary structures, unattainable by conventional FT-IR spectroscopy.
Researchers at WashU Medicine have identified two antibodies that protect animals from disease caused by alphaviruses, which could form the basis of treatments or serve as a template for a universal vaccine. The antibodies worked against all tested alphaviruses and prevented arthritis and brain infections in animals.
Hospitalized COVID-19 patients in Beijing experienced significantly shorter durations compared to SARS. Risk factors for longer hospitalization included bilateral pneumonia and lymphopenia.
Researchers found that patients with both a 22q11.22 deletion and IKZF1 changes had the worst outcomes in childhood leukemia, including almost twice the risk of relapse. The study also suggests that kids with double-deleted leukemia may need more aggressive treatment.
Researchers at the University of Texas at Austin tracked water storage in 14 major US aquifers over 15 years, finding that irrigation habits can be managed more effectively in humid regions. The study highlights the importance of surface water in replenishing groundwater, which helps dampen the impacts of irrigation.
A study by the Center for Cell-Based Therapy in São Paulo, Brazil, has discovered a set of biomarkers that can be used to predict which patients with glioblastoma may have tumors resistant to radiation therapy. The genetic signature helps doctors choose the best treatment option for these patients.
A new study finds that UK politicians with social sciences backgrounds dominate Parliament, limiting debate on STEM topics. The researchers suggest increasing STEM diversity among MPs could improve policy decisions on complex scientific challenges.
Researchers propose using junctional pacemakers to replace the sinoatrial node in patients with bicuspid aortic valve and sinoatrial node dysfunction. This innovative approach offers a new treatment strategy for managing daily life while avoiding the need for sinoatrial node replacement surgery.
A new study from Simon Fraser University found that nearly 60% of people experiencing homelessness and serious mental illness in Metro Vancouver have had a criminal conviction. The study identified factors associated with criminal convictions, including irregular income assistance payments, drug addiction, and psychiatric hospitalization.
A new study by Yale University researchers reveals that rivers are the main source of mercury in coastal areas, rather than atmospheric deposition. The Amazon River, Ganges, and Yangtze are among the top contributors, with levels highest in August and September.
A meta-analysis of 19 randomized controlled trials found that ultrafiltration is superior to control treatments for weight loss (WMD 1.24 kg) and fluid removal (WMD 1.55 L), but associated with increased serum creatinine levels. The use of ultrafiltration in ADHF patients is efficient for fluid management but less safe renally.
Researchers developed a proprietary biosensor technology with significantly enhanced molecular sensitivity using an artificial lipid membrane. The technology can detect molecules in highly ionic concentrated solutions without dilution, outperforming existing sensors.
New research from Georgetown University Medical Center found that certain brain functions associated with attention and executive control can improve in older individuals. These improvements may be due to lifelong practice and skill-building.
The study found that transgender patients taking gender-affirming hormone therapy should be monitored for changes in body weight and BMI. Transmasculine individuals experienced significant weight gain within two to four months of starting hormone therapy, while transfeminine individuals saw weight gain beyond 12 months.
Researchers at Washington State University have created a sensor that can measure the electric current produced by tiny microbes in soil, allowing for real-time assessments of soil health and potential. This breakthrough could provide farmers with valuable insights into soil productivity, enabling data-driven management strategies.
A rare rheumatoid-like autoinflammatory condition is found to be treatable with FDA-approved TNF inhibitors due to the absence of a protein that activates antiviral defenses. Researchers confirm its underlying biology and mechanisms of autoinflammation, leading to quick and substantial clinical improvement.
During the COVID-19 pandemic, U.S. alcohol retail store sales increased compared to usual trends, indicating a rise in home drinking and potential higher alcohol consumption. The study found that beer, wine, and liquor store sales increased by 17%, while food services and drinking places sales decreased markedly.
Researchers from St Petersburg University have found that small-numbered M. acentria fritillary butterflies interbreed with more common M. didyma, resulting in gene flow and increased genetic diversity. This hybridization helps maintain the species' survival chances.
Researchers develop SEND system, which uses PEG10 to package and deliver specific RNAs into target cells. This approach expands applications for nucleic acid therapy, targeting specific cell types with minimal immunogenicity.
Researchers found that referees issued more yellow cards to hometown players in 'ghost games' without fans, affecting game results. The study suggests virtual reality training could help referees overcome peer pressure and make more objective decisions.
Researchers at Nanyang Technological University (NTU) Singapore have devised a new method for producing urea, a key compound in fertilisers, through electrocatalysis. This approach produces urea five times more efficiently than previous methods and has the potential to contribute to sustainable agricultural practices.
Kai-Fu Lee will present his latest research on AI and its applications in healthcare at the 8th Aging Research & Drug Discovery Meeting. The conference aims to discuss the molecular, cellular, and organismal basis of aging and search for interventions.
The Stoffenmanager and Advanced REACH Tool models have significant deficiencies in their use, affecting chemical safety assessments. The models are based on subjective parameter values and lack physical principles, leading to uncertainty in exposure values.
Scientists have discovered a hidden 'gate' in the SARS-CoV-2 spike protein that allows the virus to infect cells. The discovery reveals a glycan mechanism that opens the gate, enabling the virus to enter host cells. This breakthrough could lead to new therapeutics to counter COVID infection.
Researchers created highly charged ions by removing 20-40 electrons from atoms and studied their interaction with solid materials. They found that the ions capture electrons from the material to become electrically neutral, a process that can be explained by simple laws.
A new study characterizes human urine-derived nutrients for sustainable agriculture, revealing three supply-demand typologies across the globe. Countries with co-located supply-demand, like India and Uganda, can reuse nutrients locally, while dislocated countries, such as the US and Australia, need concentrated fertilizer production.
Researchers from Cornell University have identified key factors in bird-plane collisions, including the time of year and species size, to inform collision avoidance strategies. The study predicts that risk for damaging strikes during periods with high migration intensity increases by up to 700%.
Researchers found that hematopoietic cell transplantation (HCT) normalizes the gut microbiota of patients with IBD associated with XIAP deficiency. The study revealed that HCT decreases gut inflammation and restores diversity in gut microbiota, improving symptoms and quality of life for affected individuals.
Researchers have identified several drug contenders that can block or reduce SARS-CoV2 infection in cells, including lactoferrin and MEK-inhibitors. These findings suggest potential efficacy against COVID-19 variants, with ongoing clinical trials to examine their ability to reduce viral loads and inflammation.
A recent study published by the American Heart Association found that excessive time spent on computers, watching TV, or engaging in other sedentary activities increases the risk of stroke among young adults. The study analyzed data from over 143,000 adults and discovered a significant association between high levels of sedentary behav...
A new catalyst and microchannel reactors improve efficiency and cost in converting alcohol into jet fuel. The process reduces complexity, improves efficiency, and lowers capital costs for renewable energy production.
A new study reveals that baby bat babbling is strikingly similar to human infant babbling, characterized by eight shared features. Researchers hope their findings will lead to further investigation into the cognitive mechanisms underlying this complex behavior.
Higher maternal weight during pregnancy may be associated with poorer offspring brain development into adolescence. The observational study found a positive correlation between maternal weight and brain development in offspring, suggesting potential long-term effects on cognitive function.
Teenagers who frequently use cannabis may have babies born preterm up to twenty years later, according to a University of Bristol-led study. The research found that daily cannabis use between 15-17 years old increased the risk of premature birth and low birth weight.
A new study found that rare single-nucleotide variants in the MX1 gene increase human susceptibility to zoonotic H7N9 avian influenza infection. These genetic vulnerabilities may act as incubators for transmission of virulent new IAV subtypes, posing a risk for pandemic viruses.
Researchers have identified a gene called Npas4 that appears to influence hundreds of other genes for timekeeping in the brain. The study suggests that Npas4 is a master regulator of many light-induced genes, which could lead to new treatments for managing challenges such as jet lag and sleep disorders.
Scientists developed a new mouse line to study protein balance and quality control in the mammalian brain. The research revealed that different neurodegenerative diseases have distinct protein misfolding patterns, offering insights into potential therapeutic options.
Researchers found that listeners use uncertainty to determine where a musical phrase ends. The study suggests the brain anticipates what comes next in a melody based on past experiences. This discovery sheds light on how humans acquire knowledge and parse complex input into manageable segments.
A new PETA paper reviews data from over 15,000 animals subjected to the forced swim test, finding no correlation with human trials. The study suggests that the test is not a reliable method for identifying antidepressants.
A new method by University of Rochester scientists documents the impact of wind on mesoscale eddies, revealing a continual loss of 50 gigawatts of kinetic energy. This discovery provides a more detailed spatial analysis than existing methods and has significant implications for understanding ocean currents and climate.
The new MIC-Drop technology enables rapid evaluation of hundreds of genes in a single experiment, improving large-scale genetic studies. Researchers can identify essential genes for healthy heart development and function.
A study by Harvard researchers found that regular walnut consumption is associated with a lower risk of death and an increase in life expectancy among older adults. The study suggests that even moderate walnut intake may have health benefits, particularly for those with poor diet quality.
A study by University of Adelaide researchers found that unregulated reptile trade in the US drives demand for illegal reptiles in Australia. Three reptile families had the highest probability of being smuggled, with species listed in CITES Appendices I having a higher smuggling probability
A recent study by Chinese Academy of Sciences researchers found that circular RNA circURI1 inhibits the spread of gastric cancer cells. It achieves this by sequestering hnRNPM, modulating alternative splicing in gastric cancer cells. This breakthrough provides a new perspective on the molecular basis of cancer metastasis.
A large retrospective analysis of 14,000 patients with colorectal cancer found that common blood-pressure drugs like ACE inhibitors and beta-blockers were associated with decreased mortality. Patients who took their blood-pressure drugs consistently were less likely to die from their cancer.
A new study found that parental smoking may increase the risk of developing rheumatoid arthritis in children when they reach adulthood. The research, published in Arthritis & Rheumatology, associated parental smoking with a 75% higher risk of developing the disease, even after controlling for personal smoking habits as an adult.
Researchers analyzed COVID-19 case data from 107 nations and found that collectivist countries, high power distance nations, and those valuing group cooperation had lower case growth. Individualistic countries and low power distance nations experienced greater case growth.
A new study from the University of South Australia reveals that Australian firms with large gender pay gaps are not only perpetuating inequality but also harming their overall performance. The research found that women executives in top management teams can lower a firm's annual return on assets by 2.2%.
A US nationwide cohort study found that nearly 85% of hospitalized COVID-19 patients were not back to their pre-COVID lives one month later. The study also revealed significant factors driving people's inability to recover, including a lack of follow-up healthcare services and new disabilities preventing daily activities.
A new study from Binghamton University tracked how practicing meditation for just a couple of months changed the brain patterns of 10 students. The results show that meditation training led to faster switching between the brain's two general states of consciousness, indicating an effect on fast switching and maintaining attention.
Researchers at the University of Maine are developing more effective, safe, and sustainable fish vaccines using nanocellulose to protect Atlantic salmon against lethal pathogens. The goal is to reduce vaccine costs and side effects while increasing effectiveness.
The Korea Institute of Machinery and Materials has developed a process to produce 'green ammonia' with zero carbon emissions, using renewable energy. The process involves combining water with nitrogen plasma, producing hydrogen and nitrogen oxides, which are then reduced to ammonia with high selectivity.
A study by Penn State researchers found that Black COVID-19 patients are three times more likely to have experienced a stroke prior to their diagnosis than non-Black patients. This disparity may explain the high mortality rates among Black populations during the pandemic.
A machine learning algorithm can accurately sex Caucasian 2D footprints with up to 90 percent accuracy, surpassing expert analysis. This breakthrough has significant implications for forensic and anthropological applications.
Long-term simulations show that smart land management, such as organic farming and protected refuge areas, can help stabilize threatened bumblebee species. Climate change is expected to have the strongest total effect on bumblebees, threatening many species.
A national survey in Japan found that men express a stronger wish for longevity than women, while having children and higher income levels also influence desires for a long life. The study sheds light on the individual attitudes toward longevity among Japanese citizens.
An international team reconstructed language families spanning over 10,000 years by combining genetics, linguistics, and musicology data. Grammar was found to reflect population history more closely than other cultural features, highlighting the importance of the grammatical factor in understanding human cultural evolution.