Washington, DC / New Delhi, India – Researchers at CDDEP, University of California, Berkeley, and the Government of Tamil Nadu recently published ‘SARS-CoV-2 infection and mortality during the first epidemic wave in Madurai, South India: a prospective, active surveillance study’ in The Lancet Infectious Diseases . The study examined data from a large-scale surveillance programme in Madurai, Tamil Nadu, to assess predictors of COVID-19 infection and mortality, and to probe the completeness of epidemiological reporting. The authors had previously published the largest COVID-19 contact tracing study in Science in 2020.
As of August 8th, 2021, India reported over 428,000 COVID deaths. While this is a significant burden, it represents a lower overall fraction of fatal cases than what other settings have shown. There are few large-scale studies examining SARS-CoV-2 infection and mortality in India, and this has hindered efforts to compare COVID-19 epidemiology against observations from other settings.
Several studies across the world have reported on the predictors of COVID-19 infection and mortality among individuals. However, none differentiate the outcomes of symptomatic or asymptomatic infection, or use community-based surveillance efforts to assess predictors of infection and mortality. This study reports on comprehensive surveillance data collected from over 440,000 SARS-CoV-2 tests undertaken through clinical and community-based outreach testing during the first wave of the pandemic in Madurai , India. It characterizes differences in risk factors for symptomatic and asymptomatic infection as well as impacts of differences in India’s demographic structure on the distribution of cases (symptomatic and asymptomatic) and deaths.
Overall, the authors observed:
According to the study’s lead author, Dr. Ramanan Laxminarayan, Director, CDDEP, “The data collection in Madurai was exceptional and permitted a study of scale and scope unlike any from other parts of the world. The findings clearly show a major role for non-communicable disease control as part of a long term Covid-19 containment strategy.”
‘ SARS-CoV-2 infection and mortality during the first epidemic wave in Madurai, South India: a prospective, active surveillance study ’ is published in the The Lancet Infectious Diseases and is available for download here: *link to be added*
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About the Center for Disease Dynamics, Economics & Policy Inc.
The Center for Disease Dynamics, Economics & Policy Inc. (CDDEP) produces independent, multidisciplinary research to advance the health and wellbeing of human populations around the world. CDDEP projects are global in scope, spanning Africa, Asia, and North America and include scientific studies and policy engagement. The CDDEP team is experienced in addressing country-specific and regional issues, as well as global challenges, such as antibiotic resistance and pandemic influenza. CDDEP research is notable for innovative approaches to design and analysis, which are shared widely through publications, presentations, and web-based programs. CDDEP has offices in Washington, D.C. and New Delhi and relies on a distinguished team of scientists, public health experts and economists.
The Lancet Infectious Diseases
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SARS-CoV-2 infection and mortality during the first epidemic wave in Madurai, South India: a prospective, active surveillance study
12-Aug-2021