Articles tagged with Heart Disease
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A Rutgers-led team has found that altering a protein called Connexin-43 may alleviate DMD-related heart disease by protecting against irregular heartbeats and late-stage failure. This discovery offers hope for prolonging the lives of muscular dystrophy patients, who are currently plagued by heart muscle breakdown.
A study of 100,902 participants found that habitual tea consumption was linked to lower risks of cardiovascular disease and all-cause death. Green tea showed the strongest association, while black tea had no significant effects.
Half of women with heart failure do not receive adequate treatment due to the underlying cause being unrelated to a heart attack, leading to progressive stiffening of the heart. Obesity and high blood pressure are significant risk factors for this type of heart failure in women.
A recent study found a 50% increase in total mortality and three-fold increase in heart disease deaths in individuals with high 3-PBA levels, a metabolite of pyrethroids. The study's findings challenge the assumption that these insecticides are safe, particularly for vulnerable populations.
A global coalition is calling for early screening and coordinated lifetime care for familial hypercholesterolemia, a condition affecting 34 million people worldwide. The initiative aims to prevent premature cardiovascular disease and save lives by leveraging scientific data, novel therapies, and technological advances.
A randomized controlled study found that Transcendental Meditation prevents abnormal enlargement of the heart and reduces chronic heart failure in African Americans. The study tested 85 hypertensive participants who practiced TM or received health education controls, with significant reductions in cardiovascular mortality and morbidity.
A study published in the European Heart Journal found that good sleep habits can compensate for a high genetic risk of heart disease and stroke. Researchers analyzed over 385,000 participants and found that those with healthy sleep patterns had a 35% reduced risk of cardiovascular disease.
A recent study published in PLOS Medicine estimates that approximately $50.4 billion of the annual healthcare cost of cardiometabolic disease in the US population is associated with suboptimal diet. The highest costs are linked to low consumption of foods like nuts, seeds, and seafood-derived omega-3 fats.
A new study found that unhealthy diets account for almost 20% of heart disease, stroke, and diabetes costs in the US. Suboptimal diets cost approximately $300 per person, or $50 billion nationally, accounting for 18 percent of all heart disease, stroke, and type 2 diabetes costs.
Researchers found that good sleep patterns can reduce the risk of cardiovascular disease by up to 35% compared to unhealthy sleep patterns. People with a healthy sleep score of 5 had nearly seven fewer cases of cardiovascular disease per 1000 people per year compared to those with a poor sleep pattern.
Researchers at SUTD have developed an acoustic fluorescence activated cell sorting (aFACS) system that isolates cells with high purity and viability. The system uses elasto-inertial particle focusing to improve sorting accuracy and efficiency, resulting in minimal cell damage and high recovery rates.
A nationwide study found that low educational levels predict a higher risk of developing or dying from heart disease and stroke. The study also discovered that low income and work stress could explain up to 54% of the increased risk among people with and without cardiovascular diseases.
MDC researchers used new imaging techniques to track titin's entire lifecycle, revealing its dynamic nature and unexpected pool of soluble titin outside the sarcomere. This breakthrough provides novel insight into muscle tissue formation and could lead to understanding of human diseases associated with mutated sarcomeric proteins.
Australian researchers have discovered a further 148 previously unknown proteins affected by oxidative stress in the human body, linked to major diseases such as heart disease and cancer. The new chemical tool developed at Flinders University's Chalker Lab has mapped over 1000 proteins modified under oxidative stress.
Researchers highlight the need to address comorbidities such as heart disease, kidney disease, and certain cancers associated with HIV. Effective treatment strategies and clinical trials are crucial to reducing the burden of these conditions on individuals and the healthcare system.
A new UBC study finds that many Canadians live with multiple chronic health conditions, including cardiometabolic diseases like stroke, heart disease, and diabetes. Lifestyle behaviors such as physical inactivity, poor diet, and high stress levels are associated with a higher risk of developing these conditions.
Researchers found that time-restricted eating can lead to weight loss, reduced abdominal fat, lower blood pressure and cholesterol, and more stable blood sugar and insulin levels. The study included 19 participants with metabolic syndrome who experienced improved sleep and a 3-4% reduction in body weight.
Changes in heart rate due to low oxygen conditions during pregnancy may predict future heart health, according to research published in the Journal of Physiology. The study used sheep models to examine the impact of chronic hypoxia on fetal heart development and identified potential markers for long-term heart disease risk.
Researchers have successfully reproduced electrical properties of biological neurons onto semiconductor chips, enabling medical devices to cure chronic diseases. The artificial neurons require only 140 nanoWatts of power, making them ideal for bio-electronic implants.
A new gene therapy aims to 'switch off' genes that promote cardiovascular disease by reducing fatty material buildup in arteries. The treatment, developed at the University of Sheffield, has the potential to slow or stop the progression of heart disease.
Research suggests that aerobic exercise and a heart-healthy diet, such as the DASH diet, can improve cognitive functioning in older adults with mild cognitive impairment. Combining exercise with the DASH diet showed promise in improving thinking, memory, and decision-making abilities.
A recent study published in the European Heart Journal has identified a potential mechanism linking long-term exposure to environmental noise and cardiovascular disease. The research found that high noise levels lead to activation of the amygdala, a deep brain structure, triggering changes that increase the risk of heart attack, stroke...
A recent study published in Cardiovascular Research found that short sleep duration contributes to the link between socioeconomic status and coronary heart disease in men. People with lower socioeconomic status often experience increased stress, noise, and financial burden, leading to less sleep and poorer health outcomes. Structural r...
Researchers at the Medical University of South Carolina have found that sphingolipid levels are associated with heart disease in African Americans with lupus. The study suggests that broader information on sphingolipid profiles could help physicians predict disease severity or assess the efficacy of anti-lupus drugs.
A Mayo Clinic-led study found that people with inflammatory bowel disease, Type 1 diabetes or blood clots may be at increased risk of developing rheumatoid arthritis. Comorbidities are linked to poorer outcomes for patients with rheumatoid arthritis, including worsened physical disability and increased mortality.
A recent review of prospective cohort studies found that consuming legumes reduces incidence rates for cardiovascular disease, coronary heart disease, and hypertension by up to 10%. Legumes benefit cardiovascular health due to their high fiber, plant protein, and micronutrient content.
Cardiovascular disease in women often presents differently than in men and may not be diagnosed. Barbra Streisand joins Noel Bairey Merz, director of the Women's Heart Center at Cedars-Sinai, to discuss these key differences.
Researchers identified 22 new mutations in the TITIN gene associated with non-ischemic dilated cardiomyopathy, a disease weakening the heart muscle. Patients with these mutations had severe cardiomyopathy and poorer outcomes, highlighting the need for genetic testing and aggressive monitoring.
A 15-year study found that peripheral arterial disease patients may not be prescribed life-saving statins at the same rate as other atherosclerotic conditions. Statin prescription rates have increased over time, leading to improved patient outcomes, but a significant treatment gap remains.
A new study reveals that people with cardiovascular disease are at higher risk of developing cancer, while those with more risk factors for heart disease are also more likely to develop cancer. Lifestyle habits that reduce heart disease risk, such as a healthy diet and regular exercise, may also help prevent some cancers.
Researchers found that women who consumed more calories in the evening had poorer heart health, with a higher proportion of daily calories after 6pm linked to increased cardiovascular disease risk. The study suggests that intentional eating habits can be a simple and modifiable behavior to help lower heart disease risk.
A study presented at the American Heart Association's Scientific Sessions found that racial bias can influence decision-making for advanced heart failure therapies, particularly for black patients. African immigrants who reported more experience of discrimination were also found to have a higher risk of cardiovascular disease risk fact...
Research suggests female veterans with posttraumatic stress disorder (PTSD) have higher rates of diabetes, high cholesterol, high blood pressure, tobacco smoking, and obesity compared to those without PTSD. This increased risk may put female veterans with PTSD at a greater risk for developing heart disease.
Researchers implemented the Northeast Health Equity Consortium to address heart disease and stroke disparities in at-risk communities. The initiative helped states achieve major goals for eliminating health disparities, including over one million free blood pressure screenings.
Research links depression to increased odds of heart disease and stroke, with a 24% increase in risk for each additional level of depression severity. The study analyzed data from over 11,000 adults diagnosed with depression and found a significant association between depression and non-fatal heart disease.
Researchers found that women with stable heart disease experienced a higher risk of major cardiovascular events after a stressful activity, compared to men. The study measured inflammatory biomarkers in response to stress and tracked participants for three years.
A study found that almost 1 in 3 heart disease patients skip the flu shot, with uninsured individuals having the highest non-vaccination rate. Flu vaccinations are proven to prevent illness and death in people with heart disease, emphasizing the need for education and vaccination efforts.
A 10-year study found that middle-aged men with higher muscle mass had a lower risk of heart attack and stroke. The researchers suggest that preserving skeletal muscle mass through regular physical activity and a protein-rich diet may help reduce cardiovascular disease risk.
A study by Washington State University researchers shows a decline in new cases of heart disease among American Indians over a 25-year period. Fewer Native men are dying from heart-disease-related events, while overall prevalence of heart disease has decreased more in women.
For patients with cerebral ataxia, researchers linked specific biochemical changes in the CHIP protein to disease characteristics. Limiting mutant CHIP protein activity may decrease symptom severity.
A large Chinese study found that insomnia symptoms are associated with a higher risk of stroke and heart attack. The research, published in Neurology, followed over 487,000 participants for an average of 10 years and found that those with insomnia symptoms were 18% more likely to develop these diseases.
Researchers developed a gene therapy combining FGF21 and ?Klotho treatments to target multiple age-related diseases. The single-formulation treatment successfully treated obesity, type II diabetes, heart failure, and renal failure in mice.
Kaiser Permanente research identifies a national trend of increasing deaths due to heart failure among US seniors, with over 647,000 people dying from heart disease in 2017. The study highlights the importance of addressing heart health in older adults as the population continues to age and grow.
Consuming fish, fruits, nuts, whole grains, olive oil, and vegetables reduces risk of mortality and diet-related diseases, while unprocessed red meats increase risk. These dietary changes may also support environmental sustainability by lowering environmental impacts.
Research found that offspring of obese rat mothers showed impaired mitochondrial function, leading to early signs of diabetes and increased susceptibility to heart disease. Exercise improved these outcomes, suggesting a potential therapeutic benefit.
New research reveals that maternal obesity accelerates the aging process in offspring, leading to increased susceptibility to diabetes and heart disease. Exercise by the offspring can help mitigate these risks, highlighting the importance of early life conditions on future health outcomes.
A new metabolic discovery by researchers at Cornell University may hold the key to fighting heart disease and Type 2 diabetes. The study identifies two enzymes that convert glucose to erythritol, a sugar alcohol, in human metabolism.
A new study published in the Journal of the American Heart Association found that sleeping less than six hours per day can significantly increase the risk of heart disease and stroke. Middle-aged adults with high blood pressure, Type 2 diabetes, or heart disease are particularly at risk, according to researchers.
A study published in CMAJ found that heart disease increases the risk of hospitalization for allopurinol-related severe skin reactions. People with specific genetic markers, such as HLA-B*5801, are at higher risk. The risk is further increased when combined with kidney disease.
Researchers at the University of Cambridge found that people who achieve weight loss of 10% or more within five years after diagnosis are more than twice as likely to go into remission. This suggests that significant calorie restriction and weight loss can reverse type 2 diabetes.
A new study found that halving red and processed meat consumption reduces LDL 'bad' cholesterol levels and heart disease risk by an average of 10%. Researchers discovered that even small changes to RPM intake can induce significant changes in LDL cholesterol, potentially reducing the risk of developing heart disease.
A study published in the Journal of the American Heart Association found that on-the-job pesticide exposure raised the risk of heart disease and stroke in Japanese American men. After 34 years of follow-up, no significant link was found between pesticide exposure and cardiovascular disease.
Individuals with familial hypercholesterolemia face a high risk of heart attack and stroke despite receiving multiple cholesterol-lowering treatments. The study found that only 52% of adults with FH meet LDL-cholesterol targets, highlighting the need for more aggressive treatment.
A study analyzing humans, chimpanzees, and gorillas reveals the human heart adapts to endurance activities by becoming larger, longer, and more elastic. However, there is a trade-off between these adaptations, making it harder for individuals with one type of adaptation to cope with the other.
A new two-minute focused cardiac ultrasound protocol can help veterinarians detect heart disease in cats earlier, potentially saving lives. The test, developed by researchers at Tufts University, has been shown to be successful in detecting moderate and severe heart disease with high accuracy.
Researchers at Penn Medicine successfully harnessed CAR T-cell therapy to target and remove activated cardiac fibroblasts, significantly reducing cardiac fibrosis and restoring heart function in mice with heart disease. The approach demonstrates potential for treating heart disease, a leading cause of death worldwide.
Researchers create biomaterial-based models of heart tissues to understand the impact of aortic valve replacement procedures on cardiac tissue remodeling. The study reveals key proteins associated with myofibroblast deactivation and offers potential for developing innovative therapies for fibrotic diseases of the heart.
A study published in PLOS Biology has identified conserved proteins and pathways in four major animal models and humans, revealing unique sets of proteins mutated in human disease states. This discovery allows researchers to select the most appropriate model systems for studying cardiac development and investigating diseases.
Research suggests that central blood pressure, measured at the aorta, can more accurately reflect heart disease risk in individuals with treatment-resistant high blood pressure. This measurement may help tailor blood pressure treatment and reduce heart disease risk for affected patients.
Researchers at CNIC discover strategies to inhibit kinase GSK3? in mice with ARVC5, reducing fibrosis and improving heart function. The study aims to translate the results to patients and investigate gene therapy strategies for potential cure.