Researchers at the University of Illinois have developed a new compound called ErSO that kills 95-100% of cancer cells in mouse models of human estrogen-receptor-positive breast cancers and their metastases. The compound targets the anticipatory Unfolded Protein Response pathway, which is already active in many breast cancer cells.
Navdeep Kaur Brar has been awarded the IADR John A. Gray Fellowship to support her research on antibiotics and microbiome impact. The $10,000 fellowship aims to provide training and experience in dental or related research.
The American Association for Dental Research (AADR) has announced the winners of its 2021 411 Rapid Research Competition. In the Basic Science category, Juhi Uttamani from the University of Illinois at Chicago won first place with her research on miRNAs in periodontal inflammation, while Mary Younan from the University of Texas took se...
Researchers chronicle African dust transport across North Atlantic, highlighting its essential role in marine and terrestrial ecosystems. The study also explores the link between dust transport and African climate, shedding light on Earth's largest source of dust.
Spotted hyenas inherit advantageous social networks from their mothers, which affect their health and longevity. Higher-ranking mothers imprint these networks on their cubs more accurately, leading to longer life and reproductive success.
Researchers identified six novel molecular subtypes of thymic epithelial tumors that are independent of World Health Organization histologic type. The study used genomic information from The Cancer Genome Atlas dataset and the IU-TAB-1 cell line, and found no association between WHO histologic subtype and molecular subtypes.
Researchers observed signs of spin-triplet superconductivity in magic-angle trilayer graphene, which resists high magnetic fields and could improve MRI technology. This exotic material's ability to persist superconducting under strong magnetic fields has the potential to revolutionize technologies like quantum computing.
Lois Cohen, a renowned researcher, has been awarded the IADR Distinguished Scientist Award in Global Oral Health Research. Her extensive career has spanned over 55 years and focused on linking behavioral and social sciences to public health issues.
A new study reveals that older people are slower to learn actions and behaviors that benefit themselves, but are just as capable as younger people of learning behaviors that benefit others. When making choices that give positive feedback to another person, older adults' learning ability is preserved.
Kiyoshi Koyano, a renowned prosthodontist, has received the IADR Distinguished Scientist Award for his outstanding research contributions to the field of prosthodontics and implants. He is recognized as a prominent scientist in Japan, with numerous international positions and publications on clinical practice and prosthodontics.
Hazem Abbas, a Ph.D. student at Tohoku University, Japan, received the IADR Lion Dental Research Award for his research on social determinants of health and their relation to oral health outcomes. The award aims to support improvements in oral health sciences through innovative research.
A survey of over 650 astronomers and geophysicists reveals a systemic bullying problem, with disabled and black/minority ethnic individuals facing higher rates of bullying. Women and non-binary individuals are also more likely to experience bullying and harassment in the workplace.
A team of researchers has uncovered the intricate cellular mechanism behind calcium's role in regulating energy supply to specific brain regions. By studying calcium signals in capillaries, they found that increased calcium levels trigger nitric oxide production, leading to vessel relaxation and enhanced blood flow.
Researchers analyzed 1.95 million family units, finding a low overall rate of misattributed paternity (1.7%) with rates closer to 1% in recent decades. The study's findings suggest that misattributed paternity is unlikely to have significant effects on hereditary condition studies.
A study published in Nature Communications reveals the visual system retains information from moving images, providing a consistent representation of surroundings. The researchers found that neuronal responses in deeper layers of the visual cortex exhibit 'perceptual constancy' and 'intrinsic persistence', ensuring stable encoding and ...
Current carbon capture technologies require significant energy output, making them less than optimal. Researchers are working on developing more efficient methods using solid sorbents and membranes, which already show promise in concentrated CO2 emissions sites.
Twenty-nine percent of Americans increased supplement use during the pandemic, citing enhanced immunity and overall well-being as reasons. Despite this, many people are unaware of the risks and safety issues associated with supplement use, according to a survey conducted by The Harris Poll on behalf of Samueli Foundation.
A group of leading doctors and health experts warn that the UK government has failed to deliver on its promise to make England smoke-free by 2030. The smoking rate remains high, with over 200,000 children under 16 starting to smoke in the last two years.
The American Association for Dental Research recognized Ning Yu, a researcher at The Forsyth Institute, for her contributions to periodontal research. Yu received the $10,000 USD fellowship to support women researchers in early stages of their careers and promote diversity in the field of oral biology.
A global consensus statement identifies key issues in healthcare for people living with HIV, prioritizing multimorbidity, health-related quality of life, and stigma reduction. The panel recommends new monitoring processes and guidelines to ensure the long-term well-being of millions worldwide.
A team of scientists proposes a way to control all properties of photonic qubits using modulated quantum metasurfaces. This technology could enable secure communication, sensing and imaging, as well as harnessing energy from photons.
Researchers have created a dynamic model that accurately recreates hemodynamic loads on engineered heart muscle tissues, providing unprecedented insights into how genetics and mechanical forces contribute to heart muscle function. This breakthrough model allows for the study of various heart diseases with genetic mutations, development...
The study contributes to deciphering genetic background of unique marsupial characteristics by creating genetically modified opossums. The researchers successfully edited a gene responsible for body pigments, producing albino offspring with inherited genes.
Patricia Miguez, a tenure-track Assistant Professor at the University of North Carolina, Chapel Hill, has won the AADR Procter & Gamble Underrepresented Faculty Research Fellowship. The fellowship supports her research on the extracellular matrix and its modifications in health and disease, with a focus on craniofacial region.
A team of chemists from Waseda University in Japan has synthesized aryl sulfides without using thiols, a toxic and smelly compound. The new method uses a nickel catalyst and environmentally friendly aromatic esters as feedstock, showing promise for both laboratory and industrial-scale applications.
Researchers studied dairy cow behavior by making them walk in a straight line to identify optimal gaits. The study provided valuable insights into kinematic characteristics of normal gait, enabling the development of more efficient breeding programs.
Researchers identified cardiovascular test results that may indicate high-risk COVID-19 patients, including low left ventricular ejection fraction and tricuspid annular plane systolic excursion. These findings suggest clinical parameters can help predict in-hospital mortality for COVID-19 patients.
Scientists have developed a new model to predict the health of coral reefs using data from the Khaled bin Sultan Living Oceans Foundation's Global Reef Expedition. The model identifies key drivers of coral reef health, including biophysical and anthropogenic factors.
Researchers found that Papua New Guinean highlanders have physical traits counteracting hypoxia, such as smaller height and waist, larger lung volume and chest depth, and higher haemoglobin concentration compared to lowlanders. These adaptations may be a result of living at altitude for 20,000 years.
PlantwisePlus will test new interventions in 6-7 countries to reduce crop losses and empower farmers to increase incomes, food security, and food safety through sustainable approaches. The program aims to accelerate the availability of nature-positive plant protection products and create employment to support economic development.
A study analyzed 11 years of data to find that 37% of Congress members own or have owned healthcare-related assets. The average value of these assets was $43,000, indicating a significant potential for conflicts of interest.
A study in the Journal of School Health monitored 1,154 students for asymptomatic COVID-19 cases during high community transmission. The researchers found no transmission linked to bus transportation, despite near-capacity operations with universal masking and ventilation.
A new randomized controlled trial found that Transcendental Meditation significantly improved emotional stress symptoms, quality of sleep, and English Language Arts academic achievement in high school students. The study showed that meditation was more effective than sustained silent reading in improving academic outcomes.
The project aims to identify potential environmental costs of deep-sea activities to inform responsible use. It will connect diverse science and policy experts in industry, academia, and private institutes to guide sustainable practices.
Researchers at Weill Cornell Medicine have discovered that injecting mice with pulmonary endothelial cells can reverse the symptoms of emphysema. The study found that targeting endothelial cell function may represent a strategy for treating patients with advanced COPD or emphysema. Injecting healthy lung endothelial cells and/or inhibi...
Researchers have found a material that exhibits superconducting properties at extremely low temperatures, providing new insights into high-temperature superconductivity. The discovery was made by studying an unusual 'strange metal' called YbRh2Si2, which showed linear resistance and temperature relationships.
The B.1.617 variant infects lung and intestinal cells more efficiently than the original virus, reducing antibody effectiveness in protecting against infection. This may lead to increased transmission among vulnerable populations.
A new tool called the 'scene wheel' is being used to study how accurately people construct mental representations of visual experiences. The wheel uses highly realistic images and deep-learning methods to simulate everyday visual experiences, allowing researchers to test the validity of classic findings in the field.
Karan Jani's Gravitational-Wave Lunar Observatory for Cosmology aims to analyze black hole and dark matter mergers with unprecedented sensitivity. The moon's environment offers an ideal backdrop for the observatory, lacking atmosphere and seismic noise, making it a crucial step towards discovering new physics.
A recent study published in the New Zealand Journal of Ecology found that alpine-based hedgehogs hibernate in the same areas they used in summer and do not migrate to lower elevations. This discovery suggests that hedgehogs are residents in these zones, rather than just visitors.
Gender-affirming hair removal procedures were associated with reduced rates of past-month severe psychological distress, past-year smoking, and past-year suicidal ideation. The study analyzed data from the 2015 U.S. Transgender Survey.
A new analysis reveals that global toxic pollution and climate change disproportionately affect low-income countries, with the top-one-third of at-risk nations accounting for over two-thirds of the world's population. The study provides a list of top-ten countries most equipped to immediately begin risk reduction efforts.
A new recipe combining chickpea flour and psyllium has resulted in a more nutritious and acceptable gluten-free bread. The product contains high amounts of fiber, proteins, vitamins, and minerals, and has been rated highly by consumers in qualitative surveys.
A University of Otago study reveals that high proportions of renewable generation coupled with energy storage is technically and economically viable for Samoa's electricity system. The results show that setting targets below 100% and considering biomass options can make renewable energy more attractive and affordable.
Researchers found that wearing exoskeletons while performing tasks requiring mental effort can lead to brain overwork and decreased efficiency. The devices may not be as effective as initially thought in alleviating stress on lower backs.
A new testing capability has been developed at Sandia National Laboratories to simulate multiple environments on a full-scale weapons system, producing richer data and improving test repeatability. This allows engineers to validate weapon design and systems performance more efficiently.
A randomized clinical trial found that semi-annual application of 5% sodium fluoride varnish significantly reduces approximal caries development in primary teeth compared to 38% silver diamine fluoride and placebo controls. The study evaluated 4-6 year-old children with at least one sound approximal surface.
A study by Max Planck Institute researchers found that bacteria on sand grains in the North Sea and Arctic remain consistent throughout seasons. The community's stability suggests a lack of available space for new inhabitants.
Researchers simulated 3 million swimming race times to show that certain quartzite oscillator-based devices round times incorrectly. This can result in changes of one one-hundredth of a second, potentially affecting the outcome of sporting events.
A new perspective piece highlights the need for a more complex approach to defining carbohydrate quality, considering nutrient intakes, balanced diets, and environmental impact. The authors propose several potential quality indices, including whole-grain, fiber, and protein content, to establish a standardized metric.
Rosa, an Associate Professor at NUS Faculty of Dentistry, received the award for his work on atom-thin materials for biomedical applications and dental pulp regeneration. He will serve a two-year term on the IADR Board of Directors.
Scientists use infrared sensors to study the nighttime weather of Venus, discovering that north-south winds run in the opposite direction at night. This observation could help build more accurate models of the Venusian weather system and provide insights into Earth's weather patterns.
Engineered nanostructures overcome problems in gas-based high-harmonic generation, enabling scientists to observe molecular dynamics with a single laser shot. The record-breaking conversion efficiency covers a wide range of photon energies, opening up new opportunities for studying matter at ultrahigh fields.
Scientists at St. Jude Children's Research Hospital have found a link between post-cancer treatment frailty and neurocognitive decline in young adult childhood cancer survivors. Frailty contributes to early onset of neurocognitive decline, which can influence daily activities.
A new clinical trial aims to test a personalized treatment for severe asthma targeting a specific mutation found disproportionately in people of color. The trial, led by Boston Children's Hospital, will test dupilumab, an existing drug that blocks the mutated IL-4 receptor, in patients with and without the mutation.
A study of 1,741 women and 620 men aged ?65 years found that cognitive decline is linked to accelerated bone loss and a higher risk of fractures in women. The bidirectional relationship between bone loss, cognitive decline, and fracture risk suggests shared underlying factors.
Research at North Carolina State University reveals that soil microbes significantly impact heterosis, or hybrid vigor, in corn plants. In experiments with sterile bags and field tests, hybrid lines outperformed inbred lines due to microbial effects on root growth and biomass.
A new saliva collection method involves self-collection by licensed dentists followed by mailing to a laboratory, demonstrating feasibility for large-scale analysis. This approach offers a cost-effective alternative for COVID-19 diagnostics, preserving saliva samples for up to 7-10 days at room temperature with stabilizers.
Christopher Murray, a renowned physician and health economist, has been recognized for his significant contributions to global oral health. His work on the Global Burden of Disease project has led to improved understanding of the impact of dental diseases on disability-adjusted life-years worldwide.
Nisha D'Silva, a University of Michigan professor, is recognized for her exemplary mentoring skills, having mentored over 60 students and post-doctoral fellows in oral pathology and cancer biology.