A new study refutes a long-standing explanation for low energy efficiency in lithium-ion batteries, suggesting that voltage hysteresis is caused by reversible electron transfer between oxygen and transition metal atoms. This phenomenon could be mitigated through manipulation of electron transfer barriers.
Organs-on-chips can assess drug efficacy better than traditional methods, reducing the risk of failed clinical trials. These systems enable human multi-cell-type models and personalized medicine by seeding with a patient's own cells.
The article highlights the need for financial and technological support to enable effective interprofessional teams in primary care. The authors suggest training community members to serve their communities and exploring how diversity impacts patient care outcomes. They also advocate for innovative payment models that allow primary car...
Researchers from Kaunas University of Technology and the University of Helsinki have developed a nutritious meat analogue using fermented okara, which can help alleviate digestive problems due to its probiotics. The product contains less salt and saturated fats than real meat while maintaining protein levels.
Researchers at Princeton Plasma Physics Laboratory have identified a chemical pathway to produce boron nitride nanotubes, a material with properties similar to carbon nanotubes but more difficult to produce. The breakthrough could lead to large-scale industrial production of the nanomaterial for various applications.
Reproductive complexity in plants arose in two pulses, corresponding to the origin of seeds (~375 million years ago) and flowers (~125 million years ago). These pulses are characterized by significant evolutionary innovations, including the diversification of flowering plants.
A new study confirms that Rockefeller University's saliva test is as sensitive, if not more so, than FDA-authorized nasal and oral swab tests. The test has been used tens of thousands of times to identify and isolate infected individuals on campus and has the potential to improve safety in communities.
Researchers have found that the cave was occupied by Neanderthals during a longer period of time than previously thought, from 94,000 to 59,000 years ago. The study also reveals evidence of modern human activity, such as fires, in the cave.
Researchers found daily and seasonal fluctuations in chemical conditions despite long-term ocean acidification trends. Massive cycles occur every five to 10 years, causing extreme events that stress sensitive organisms.
Scientists discovered hot-band absorption (HBA) in FDA-approved Indocyanine Green, enabling advanced anti-Stokes fluorescence bioimaging. HBA-based ASF has high thermal sensitivity and allows for IR perception, making it suitable for applications such as tumor detection and blood vessel imaging.
Researchers from the University of Tsukuba found that warm sea surface temperature conditions in the Indian Ocean contribute to anomalous weather events in East Asia, including record-breaking rainfall and severe flooding. The study suggests a link between warming Indian Ocean conditions and stagnation of the Meiyu-Baiu rainband.
Scientists from Trinity College Dublin have developed tiny, color-changing gas sensors using new materials and 3D printing techniques. These sensors can detect solvent vapors in air and have potential applications in wearable devices for health monitoring and low-cost environmental monitoring systems.
A textile-based implant containing cartilage derived from stem cells reduced pain and restored hip joint function to baseline levels in a study of dogs with moderate osteoarthritis. The implant successfully integrated into the hip joints, effectively resurfacing them and allowing the dogs to regain activity levels.
Researchers from NUS Yong Loo Lin School of Medicine have discovered that glioblastoma cells depend on biotin distribution to grow and invade. This finding suggests that targeting biotin-dependent metabolic enzymes and epigenetic pathways may be a viable approach for treating glioblastoma.
Researchers at Penn State have imaged a protein facilitating RNA modification, allowing them to reconstruct the process. The study reveals how a chemical tag is added to tRNA, improving its ability to translate messenger RNA into proteins.
Researchers at GEOMAR found that seagrass meadows absorb vibrios, reducing their presence by up to 63% compared to non-vegetated areas. This discovery highlights the importance of protecting and restoring these ecosystems to maintain healthy water quality.
A recent study published in Nature Medicine reveals that countries in Africa previously thought to be at greatest risk from Covid-19 were actually the worst affected. Nations with large urban populations and strong international travel links had higher mortality rates and lower levels of restrictions.
Ground-breaking Curtin University-led research has discovered a probable 'blood-to-brain pathway' that can lead to Alzheimer's disease. The study suggests that toxic protein deposits may leak into the brain from fat-carrying particles in blood, opening up potential new treatments.
The project aims to digitize three million plant specimens from US herbaria and combine with data from Asia and Europe, accelerating research on endangered species and plant biodiversity. The Harvard University Herbarium will lead the effort, connecting institutions in the US, Europe, and Asia.
A study in Cell Reports identifies a new pathway regulated by cytokine GDF15, which activates AMPK protein and regulates energy metabolism in peripheral tissues. The discovery offers potential therapeutic targets for treating metabolic diseases such as type 2 diabetes.
Researchers have identified a mechanism to control R-loop regulation, which could lead to new drugs for cancer and dementia. The study found that three proteins work together in a pathway to optimize R-loop levels, with potential applications for treating various conditions.
A new fly species, Scenopinus jerei, has been officially described from Finland, belonging to the primitive and species-poor family of window flies. The species is found in boreal forest habitats and is widespread but rare in Finland, with its larvae preying on other insects.
Researchers developed an AI tool using data from hospitals across four continents to predict oxygen needs of hospital Covid patients anywhere in the world. The study achieved high-quality predictions with a sensitivity of 95% and specificity of over 88%, demonstrating the transformative power of federated learning in healthcare.
A new study published in PLOS ONE found that children born with congenital Zika Virus-related microcephaly have varying levels of neurodevelopmental impairment. The researchers used a routine neurological assessment to track the children's development, revealing differences in cognitive and motor skills. The findings suggest that HINE ...
A new study found that psychological interventions can have a significant effect on the treatment of subthreshold depression in adolescents. The meta-analysis showed that approximately eight adolescents need to be treated to see one more positive outcome than no treatment, with moderate effects size.
A recent study measured 60 DBPs in three types of tea and found that brewed tea contained significantly lower levels of DBPs than tap water. However, the researchers also identified 15 previously uncharacterized compounds that likely form from chlorine reactions with natural precursors in tea leaves.
The study elucidates the mechanism by which CXCL14 binds to CpG DNA and enhances innate immune responses. A complex formation between CpG DNA and CXCL14 is necessary for internalization of CpG DNA, and multiple amino acids stabilize binding.
Researchers developed Gd-doped iron oxide nanoclusters to improve MRI contrast for early-stage cancer diagnosis. The doping content increased the nanocluster's surface area, leading to stronger T2 contrast.
Researchers analyzed deuterium abundance ratios in protoplanetary disks and found significant variations within a single disk, suggesting differences in chemical composition and physical state at formation sites. The study also reveals the presence of complex organic molecules, including nitriles, in planet-forming disks.
A team of researchers led by CU Cancer Center member Jean Mulcahy Levy examined tumor samples before and after treatment with a targeted medicine. They found additional mutations that can create resistance to the therapy, highlighting the need for new treatments or combination therapies.
Researchers from Pusan National University have compiled a comprehensive review of ginsenosides, the main component of ginseng, which can prevent inflammation, diabetes, and cancer. The study provides insights into how to improve ginsenoside production through chemical and enzymatic treatments, as well as microbial action.
A study of Michigan cities under state emergency management found that the likelihood of takeover was not driven solely by financial distress, but also by factors such as race and economic status. Changes to drinking water systems were common in takeovers, often leading to poor water quality and increased bills.
A recent study published in Nature reveals that pyrogenic iron from Australian wildfires fertilized the Southern Ocean, leading to unprecedented algal blooms. This phenomenon raises concerns about the role of wildfires in spurring phytoplankton growth, which absorbs large quantities of climate-warming carbon dioxide.
Researchers at the University of Cambridge suggest that unexplained results from the XENON1T experiment could be attributed to dark energy, rather than dark matter. The study proposes a physical model to explain the findings, which may have originated from dark energy particles produced in the Sun's strong magnetic fields.
A new study found that nearly half of New York City mothers who were trying to become pregnant again before the COVID-19 pandemic began stopped in the first few months of the outbreak. Additionally, one-third of women who had been thinking about becoming pregnant but hadn't yet started trying said they were no longer considering it.
Researchers at Aalto University created unexpected droplet shapes, including squares and hexagons, by disrupting thermodynamic equilibrium with electric fields. The liquids formed into interconnected lattices and torus shapes, stable for a controlled duration.
Researchers capture detailed images of ribosome assembly using a novel gene-editing platform, providing insights into the role of 70 assembly factors and their impact on rare human diseases. The study reveals three stages of the small subunit formation process.
A recent study found that roads can extend the impact zone for western chimpanzees by an average of 17.2 km from major roads and 5.4 km from minor roads. This results in a significant decrease in population density, with the species facing mounting pressure from infrastructure expansion.
Rising temperatures are projected to decrease outdoor recreation during summers by 18% over the next 30 years, but increase winter recreation by 12% in mid-century. This shift may lead to a decline in popular winter sports like downhill skiing and an increase in winter mountain biking.
Researchers from SUTD discover a family of 2D semiconductors with Ohmic contacts, reducing electrical resistance and generating less waste heat. This breakthrough could pave the way for high-performance and energy-efficient electronics, potentially replacing silicon-based technology.
A pilot study at the University of Cincinnati found that young adults with ASD and ID can lose or maintain weight with a system of education and support in place. Participants and parents reported knowledge and behavior change, with two participants losing significant weight.
Researchers have developed a sophisticated new tool to detect and identify rare and unknown viruses and potentially deadly bacterial pathogens. The algorithm helps isolate DNA sequences shared among related organisms, enabling faster detection and identification of pathogens in clinical or wildlife settings.
A study identifies four novel subgroups of EGFR mutations that predict drug response, offering a more accurate framework to match patients with targeted therapies. The findings reveal that certain mutations respond better to specific classes of TKIs, providing new clinical opportunities for approved treatments.
Researchers synthesized a new conjugated polymer using two chemical reactions, showing it outperforms traditional methods in organic and perovskite solar cells. The Stille reaction pathway yielded superior results with efficiencies of up to 15.1% in photovoltaic devices.
Researchers found that ambient UVB radiation before COVID-19 infection was strongly associated with reduced hospitalization and death. The study suggests that vitamin D may protect against severe COVID-19 disease and death, particularly in individuals who do not produce enough vitamin D through sun exposure.
Research by University of Arizona Health Sciences identifies chronic arsenic exposure as a risk factor for developing insulin resistance and glucose intolerance. The study found that prolonged activation of NRF2 protein leads to shifts in metabolic pathways, increasing glucose production in the liver.
Researchers at KU Leuven and the Alliance of Bioversity International have developed a method to multiply coconut trees faster and store them more efficiently in gene banks. This technique allows for the preservation of coconut shoots for eternity through cryopreservation, ensuring the long-term conservation of genetic diversity.
The most common form of liver cancer is on the rise in rural areas, with men aged 60-69 and non-Hispanic Blacks disproportionately affected. Urban areas, however, have seen a decline in HCC rates since 2013, including among younger individuals and certain ethnic groups.
Researchers used a 'role-play' approach to study how Neanderthals caught choughs in caves. They found that the birds were vulnerable to artificial light and could be caught using nets or by hand. The findings suggest that catching birds was another skill of Neanderthals, which is surprising given their intelligence and adaptability.
Researchers used human-induced stem cells carrying different versions of the APOE gene to study their interaction with neurons and astrocytes. The study found that astrocytes carrying the AD-associated APOE4 gene released more cholesterol, which led to increased beta-amyloid production in neurons.
A new study found that COVID-19 led to a significant decline in births across high-income countries, with the strongest declines observed in southern Europe, while northern Europe showed little impact. The researchers attribute this variation to differences in economic disruption and social support policies.
The Ariel Machine Learning Data Challenge has announced its winners, ML Analytics and TU Dortmund University, who developed highly accurate solutions for observing exoplanet atmospheres despite instrument noise. The winning teams will receive a cash prize of €500 and present their research at various conferences.
Researchers develop a novel cell reprogramming strategy to transform glioma cells into non-proliferative neurons. This approach shows promise in slowing down the growth of GBMs and overcoming harmful side effects of conventional treatments.
A study using ALMA revealed that protoplanetary disks around five young stars are factories of organic molecules, including nitriles implicated in the origins of life. The discovery provides insights into planetary system formation and whether these systems have what it takes to host life.
A new study has shown that a single dose of typhoid conjugate vaccine (TCV) is safe and 84 percent effective in protecting against typhoid in Blantyre, Malawi. The findings are critical as typhoid is an increasing public health threat across sub-Saharan Africa.
A team of NTU Singapore scientists developed a predictive computer model called NSGA-II, which proposed strategies to reduce COVID-19 infections and deaths by an average of 72%. The model recommended timely and country-specific advice on interventions such as home quarantines and social distancing measures.
Researchers found that surface fluxes of momentum, heat, water vapor, and carbon dioxide over complex terrains are not representative at near-surface heights. Multilevel observations on towers can help derive accurate surface flux values.
Researchers found that dance impacts health in key areas, including sense of identity, belonging, and self-worth. They call for more collaboration with dancers and co-research with participants to better capture the benefits of dance on its own terms.
A survey study found that US state cannabis laws differ significantly, leading to varying dispensary staff recommendations. The study highlights the need for standardized guidelines to ensure patients receive accurate information about cannabis use.
A study by SMU Associate Professor Marko Pitesa aims to understand and improve job search skills among mid-career workers from families of lower socioeconomic status. The research highlights the impact of life circumstances, such as social obligations and constraints, on career trajectories and mobility.