A new study found a direct correlation between severe childhood obesity and increased risk factors for heart disease and diabetes in boys. The study's lead investigator noted that understanding elevated risk in children with more severe obesity can help target testing and interventions to prevent future disease.
A new study found that severely obese children are more likely to develop heart disease and diabetes, with the risk increasing as obesity severity increases. The study suggests that implementing a more complex classification system could help target interventions and treatments for these high-risk children.
Replacing saturated fats with unsaturated fats and high-quality carbohydrates has the most impact on reducing the risk of heart disease, according to a new study. Participants who replaced calories from saturated fatty acids with calories from polyunsaturated fats, monounsaturated fats, or whole grains had lower risk of coronary heart ...
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A new Harvard study reveals that limiting saturated fat in the diet is still effective in reducing heart disease risk, but only when replaced with unsaturated fats or whole grains. In contrast, swapping saturated fat for refined carbohydrates has no significant impact on CHD risk.
The BMJ investigation found that the expert report underlying the latest US dietary guidelines fails to reflect relevant scientific literature, risking a misleading picture. The guidelines affect millions of Americans and food labelling, education, and research priorities.
Research suggests that sexual activity does not increase the risk of heart attack and can be resumed after a heart attack. Most patients are safe to engage in sex again, with less than half of men and one-third of women receiving information on this topic from their doctors.
A total ban on trans fatty acids in processed foods in England could potentially prevent or postpone about 7,200 deaths from coronary heart disease over the next five years. Policies to improve labelling or simply remove trans fatty acids from restaurants and takeaways could save between 1,800 and 3,500 deaths
Studies in the September Health Affairs issue reveal declining global mortality rates for heart disease, stroke, and certain cancers, but increasing trends in diabetes, liver cancer, respiratory disease, and lung cancer deaths, particularly among women and in low- and middle-income countries.
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A new study found that higher resting heart rates and lower heart rate variability are associated with poorer ability to function in daily life and future decline in older adults. These markers of frailty were linked to a higher risk of functional decline, regardless of sex.
Research found that depressed patients with high or low blood pressure had the highest risk of major vascular events, including stroke or heart attack, at four years. The study included 35,537 patients and showed that depressive symptoms interacted with blood pressure to predict these outcomes.
The discovery reveals protein structural changes that could inform treatments for inflammatory conditions such as heart disease and colon cancer. The researchers found that two proteins, Tollip and Tom1, work together to regulate the turnover of cell-surface receptor proteins that trigger inflammation.
A new analysis found that global life expectancy has increased by six years since 1990, while healthy life expectancy grew by five years. However, the increase in healthy life expectancy has not been as dramatic, resulting in people living more years with illness and disability.
The study found that global life expectancy has increased by 6.2 years between 1990 and 2013, while healthy life expectancy rose by 5.4 years, indicating a growing gap between overall mortality rates and the impact of non-fatal conditions on quality of life.
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Research reveals that young adults, especially women, are not benefiting equally from declining heart disease death rates. Despite improvements in older adults, the annual percentage change in death rates for young men and women showed no improvement between 1990-1999 and has only fallen one percent since 2000.
A study by researchers at the University of Edinburgh found that smoking bans led to a 8% drop in stillbirths and newborn deaths in England, resulting in 1500 avoided deaths. The ban also reduced low birth weight cases by over 5000.
Researchers at the University of Otago discovered that a normal cell process called autophagy is deregulated in diabetic hearts, leading to progressive loss of cardiac cells and cardiac dysfunction. Targeting the Beclin-1 protein presents an promising avenue for new treatments of diabetes-related cardiac disease.
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A study published in the British Medical Journal found that trans fats are associated with a 34% increase in death for any reason, while saturated fats showed no clear association with an increased risk of death or heart disease. However, researchers recommend replacing high-fat foods with vegetable oils, nuts, and whole grains.
Johns Hopkins and Mayo experts suggest upgrades to current heart disease prevention guideline, focusing on improved risk prediction and personalized treatment. The new guidelines aim to clarify key points of confusion related to risk prediction and treatment of heart attacks and strokes, promoting more precise and tailored care.
A study published in The BMJ found that trans fats are associated with a greater risk of death and coronary heart disease, but saturated fats are not. The study suggests that industrial trans fats may increase the risk of coronary heart disease and calls for a review of dietary guidelines.
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A new Johns Hopkins study finds that people infected with hepatitis C virus are at increased risk of cardiovascular damage, independent of HIV. Chronic infection leads to abnormal fat-and-calcium plaques in arteries, a common precursor to heart attacks and strokes.
Researchers identified a gene called 14-3-3zeta, which controls the production of fat cells and growth. Silencing this gene in mice resulted in a 50% reduction in specific unhealthy white fat, regardless of food intake.
A recent study published in Circulation found that a traditional Southern-style diet is associated with a higher risk of heart disease. Researchers analyzed data from over 17,000 adults and found that those who consumed foods conforming to the Southern dietary pattern had a 56% higher risk of heart disease compared to those who ate it ...
A large observational study found that regular consumption of spicy foods is associated with a lower risk of death, particularly from cancer and heart disease. Participants who ate spicy foods almost every day had a 14% lower risk of death compared to those who consumed them less than once a week.
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The July special issue of Ergonomics in Design examines the health and safety effects of the sedentary workplace, exploring alternatives to sitting at work and proposed workplace design solutions. The research highlights key factors that facilitate successful office design and discusses barriers to implementing active workplaces.
A University of Pittsburgh study finds that late- and post-menopausal women have more fat around their hearts than pre-menopausal counterparts, increasing the risk of heart disease. Hormonal changes during menopause may be to blame for this shift in fat deposits.
Researchers are examining the relationship between telomere length and age-related diseases, with the goal of understanding why some people remain healthy into old age while others develop chronic disease. The £2 million study will provide a rich resource for researchers studying various diseases, including heart disease and cancer.
A study has identified a potential link between inflammation caused by rheumatoid arthritis and the development of heart valve disease, including aneurysms. The research team hopes that existing medicines that dampen inflammation could be repurposed to treat heart valve diseases.
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Certain ECG measures can identify individuals with chronic kidney disease at high risk of dying from heart disease. A panel of 5 common ECG parameters was found to enhance prediction of cardiovascular death in this population, suggesting potential novel interventions to prevent cardiovascular complications.
A new study by USC researchers reveals that residential exposure to near-roadway pollutants can cause a significant burden of heart disease, particularly among older adults. The study's findings emphasize the need for zoning buffer areas between busy roadways and new housing developments.
A new study analyzing over 135,000 deaths found that individuals with both diabetes and heart disease have substantially lower life expectancy compared to those with one or no condition. Men with two cardiometabolic conditions had an average reduction in life expectancy of 12-23 years at age 40, while women had a 20-year reduction.
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A new Northwestern Medicine research center will investigate the potential heart damage caused by excess dietary phosphate, particularly in African Americans. The goal is to find new ways to prevent and treat heart failure and build evidence for regulating phosphate in the food supply.
A new USC-led study found that heart disease is the main reason for the disparity in life expectancies between men and women, with female death rates decreasing 70% faster than male death rates after 1880. The study suggests that biological differences may be at play, with potential factors including diet, exercise, and genetics.
A team from Duke University has developed a new method to measure the aging process in young adults, finding that signs of aging can appear as early as age 26. The study used 18 biological measures to determine an individual's pace of aging, with some participants aging at rates of three years per year.
Researchers explore nanocarriers and microbubbles for efficient thrombus treatment, addressing limitations of existing drugs. The review highlights potential solutions for improving outcomes in ischemic heart disease and stroke, where millions die annually.
Researchers analyzed large genome-wide association studies of migraine and heart disease to find no shared gene variants between the two conditions. Instead, genetic variations that protected against heart disease were found in people with migraine without aura.
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Researchers estimate that mandatory salt reduction targets could prevent up to 4,500 cardiac deaths by 2025, with the greatest benefits in deprived areas. Voluntary schemes may only avoid around 1,500 deaths.
Chronic lung disease guidelines are over-diagnosing COPD in older men and under-diagnosing it in young women, according to experts. The current guidelines may lead to adverse effects of inappropriate medication or incorrect treatment, resulting in poorer outcomes.
Cardiovascular disease remains a leading cause of death in the US, with elevated cholesterol, diabetes, hypertension, obesity, and smoking contributing to half of heart disease deaths. Despite decades of progress, reducing these modifiable risk factors has not led to significant reductions in cardiovascular mortality.
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A new study found that drinking low-calorie cranberry juice cocktail can help lower the risk of chronic diseases such as heart disease and diabetes. The polyphenol-rich compound in cranberries supports natural defenses and helps achieve a balanced lifestyle to improve health.
Researchers discovered a link between heart disease and lower bone mineral density, with women more affected. The study suggests that heart disease may weaken bones, increasing risk of fractures.
Research suggests that medically complex patients with newly diagnosed Type 2 diabetes who receive early endocrinologist care have lower risk of cardiovascular events. The study, which analyzed Ontario health data, found that these patients had a 10-20% lower risk of heart attack, stroke, and death from coronary heart disease.
Researchers have identified the molecular basis for a heart condition called dilated cardiomyopathy and found a potential treatment that partially restores function to diseased cells. The study used induced pluripotent stem cells to model the disease, revealing how a key signaling pathway develops in healthy vs. diseased cells.
Research published in the journal Heart found a strong association between daily chocolate consumption and reduced cardiovascular disease risk. Participants who ate more chocolate had lower risks of heart disease, stroke, and related death.
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A new five-year grant aims to develop novel treatments for diseases that inhibit blood cell growth and abnormalities in the bone marrow environment. The study focuses on the role of laminin in maintaining healthy bone marrow and identifying potential targets for treating bone marrow failure syndromes.
A Swedish study found that interventions among healthy people were the key to saving lives, with changes in risk factors such as smoking cessation, diet, and blood pressure levels contributing significantly. The greatest impact was seen in people over 55, highlighting the need for a broader approach to health promotion.
The study found a significant association between birth month and disease risk, with people born in May having the lowest risk of disease and those born in October having the highest. The researchers identified nine types of heart disease that correlated with seasonal effects, including atrial fibrillation and congestive heart failure.
The National Psoriasis Foundation has awarded five Translational Research Grants to researchers investigating the causes of psoriasis and psoriatic arthritis. The grants will support studies on genetic risk factors, gut bacteria, and targeted treatments for these conditions.
A large prospective study found that individuals with higher HDL function have a lower risk of developing coronary heart disease. Researchers from the University of Pennsylvania analyzed data from over 25,000 participants and discovered a strong correlation between HDL function and reduced heart disease events.
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A study found that a common mutation in the SCARB1 gene is associated with an increased risk of heart disease, especially among men and African Americans. The mutation was linked to a 49% higher risk of heart disease in African American males compared to white males.
A study published in The BMJ found that cholesterol-lowering drugs are associated with a 30% lower risk of stroke in healthy older adults. No association was found between drug use and coronary heart disease, but the results suggest that lipid-lowering drugs might be considered for preventing stroke in older populations.
Researchers predict that personalized medicine interventions could generate significant healthcare gains, including a $607 billion reduction in heart disease incidence. However, weak incentives to develop these interventions hinder their adoption, and experts suggest reimbursement reform could strengthen manufacturers' incentives.
Research found that traumatic life events, such as losing a loved one or experiencing a life-threatening illness, increased the risk of heart attack in middle-aged and older women. Additionally, a history of financial struggle was independently associated with a two-fold higher risk for heart attack.
A new study published in the European Heart Journal found that chronic obstructive pulmonary disease (COPD) significantly increases the risk of sudden cardiac death (SCD). Researchers discovered a 34% increased risk overall and an almost doubling of SCD risk after five years of diagnosis.
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Research reveals that detection rates of critical congenital heart disease before birth have improved, but disparities remain in poor and rural communities. The study found that those living in these areas are less likely to receive a diagnosis before birth due to limited healthcare resources.
A new approach to combating tuberculosis aims to harness the body's natural anti-microbial process, autophagy, to target Mycobacterium tuberculosis. Autophagy is being researched for its potential role in various diseases, including heart disease and neurodegenerative disorders.
A research program led by Carlos M. Ferrario aims to unravel the mechanisms of novel peptides in heart disease and atrial fibrillation. The team will conduct studies to evaluate new therapies to halt the progression of heart disease.
A recent study published in Psychosomatic Medicine found that mental disorders and physical diseases often co-occur in teenagers. The strongest correlations were found between affective disorders (e.g. depression) and diseases of the digestive system, as well as anxiety disorders and arthritis. These associations highlight the need for...
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Researchers found that financial constraints, transportation problems, and stigma associated with the disease were major barriers to accessing penicillin injections. Despite these obstacles, patients reported personal motivation and injection reminders helped them stay on schedule and manage their symptoms.
A Johns Hopkins report provides clinicians with concrete tips to help patients decide whether to take statins, balancing benefits and risks. The report emphasizes the importance of individualized advice, clear explanation of benefits and risks, and shared decision-making.
A recent study has found that post-traumatic stress disorder (PTSD) is associated with a nearly 50% greater risk of developing heart failure among veterans. The research adds to growing evidence linking PTSD and heart disease, suggesting a potential causal relationship between the two conditions.