Research on the causes and treatment of heart disease. Covers light exposure and heart health, sex differences, heart-in-a-dish models, and cardiac risk.
A study of 5,820 Japanese-American men found that avoiding health risks like smoking and obesity can lead to a longer and healthier life. The researchers identified several risk factors associated with healthy survival, including high grip strength, physical fitness, and avoiding excessive drinking.
Researchers at UT Southwestern Medical Center discovered that tiny RNA molecules, called microRNAs, play a significant role in causing heart enlargement and increasing the risk of heart failure. By manipulating these microRNAs, it may be possible to treat heart disease.
A recent study found that high blood glucose is responsible for approximately 2.2 million cardiovascular deaths and 1.5 million ischaemic heart disease deaths worldwide. The findings highlight the significant burden of high blood glucose on mortality from these conditions.
A recent study found that Hodgkin's lymphoma survivors who undergo lipid screening every five years live six months longer than those without screening. The study suggests that regular cholesterol screening is a cost-effective procedure to reduce the risk of heart disease in these patients.
A 20-year study of over 82,800 women found no association between low-carb diets and coronary heart disease risk. However, a diet with moderate carbohydrate reduction, emphasizing vegetable-based fat and protein, was associated with a 30% lower risk of CHD.
The study will recruit 16,000 participants aged 18-74 and follow them over time to identify the prevalence of diseases, disorders, and conditions. It aims to understand the role of cultural adaptation and disparities in disease development.
The Einstein College of Medicine has been selected to conduct a landmark study on the health status of 4,000 people of Hispanic/Latino origin in the Bronx. The six-year study will investigate various diseases and disorders affecting the Hispanic population, including heart disease, diabetes, and cognitive impairment.
Eating a Mediterranean diet rich in fruits, vegetables, and olive oil is associated with a significantly lower risk of Alzheimer's disease. The study found that individuals with the highest diet scores had 68% lower odds of developing the disease, despite controlling for age and body mass index.
Researchers found a genetic link between APOA5 and heart disease risk, specifically in those consuming high amounts of omega-6 fatty acids. Carriers of the gene variant who ate more than six percent of total calories from omega-6s had increased triglyceride levels and elevated lipoprotein particles.
Researchers found a positive association between periodontal disease and coronary heart disease, particularly in individuals under 60 with significant alveolar bone loss. The study suggests that chronic infections and inflammatory responses from periodontal disease may contribute to the development of atherosclerosis.
Researchers at Oregon State University have developed a new technique to visualize and measure superoxide in animal cells, offering a breakthrough in understanding degenerative diseases such as Lou Gehrig's Disease, heart disease, diabetes, and aging. The discovery could significantly speed up research on these conditions.
A study led by USC researchers found that low-income adults are more likely to have high levels of C-reactive protein (CRP), a risk factor for heart disease. This association may be linked to the effects of poverty on health, particularly among African Americans, Hispanics, and women.
Researchers at the University of Pennsylvania School of Medicine have found that deleting an inflammation enzyme in mice slowed the development of atherosclerosis. The study suggests that a new class of nonsteroidal anti-inflammatory drugs (NSAIDs) may benefit the heart and reduce its risk of disease.
A recent study reveals that older women have as many risk factors for heart disease as men in their 60s and more by their 70s. The research, led by USC demographers, shows a shift from previous decades where older men were at greater risk.
A study suggests that more aggressive treatment with statins is necessary to lower LDL cholesterol in patients with metabolic syndrome and coronary heart disease. The analysis found that intensive therapy with atorvastatin significantly reduced the risk of major cardiovascular events, particularly in patients with metabolic syndrome.
The article highlights the alarming rate of chronic diseases and injuries in Latin America and the Caribbean, with seven out of ten deaths attributed to these causes. The authors argue that lack of funding for health research is hindering efforts to address this crisis.
A study of over 68,000 patients in 44 countries found that Eastern Europeans and Middle Easterners have the highest rates of heart attacks, strokes, and deaths from these conditions. The analysis suggests that cardiovascular disease is no longer exclusive to Western, industrialized world.
A new drug has been shown to improve blood flow in diseased arteries by reactivating a damaged enzyme, reducing the risk of high blood pressure and heart attacks. The discovery is a significant development for the treatment of cardiovascular disease and aims to challenge orthodox thinking on heart health.
The Microscale Life Sciences Center at ASU has been awarded a five-year $18 million grant to continue its research on cell growth and death, aiming to understand the nature of disease processes. The center will develop miniature automated systems to analyze differences between healthy and diseased body cells.
The NHLBI's new guide to lowering cholesterol with TLC emphasizes the importance of a three-part program of diet, physical activity, and weight management. The guide provides tips on reducing saturated fat, trans fat, and dietary cholesterol, as well as strategies for increasing soluble fiber and plant stanols and sterols.
The UK Biobank project, a £61m initiative to study complex interactions of genetic and lifestyle factors in disease and health, has received unanimous backing from international experts. The pilot phase showed promising results, paving the way for nationwide rollout.
Researchers found that patients with low BMI had a higher risk of death than those with normal BMI, while overweight individuals had better survival rates. The study suggests that alternative methods are needed to characterize individuals with excess body fat accurately.
Chagas' disease kills 50,000 people annually, with 18 million already infected and 100 million at risk. The disease has no initial symptoms, expensive prevention methods, and limited treatment options, prompting The Lancet to call for increased research attention.
The NHLBI guide provides information on the impact of physical activity on your heart, including tips for incorporating physical activity into daily life. Regular physical activity is essential for maintaining a healthy heart, with benefits including burning extra calories, building stamina, and improving balance.
Older adults who drink lightly to moderately may live longer and have a reduced risk for cardiac events than those who do not drink. Light to moderate drinking has been shown to reduce levels of C-reactive protein and interleukin-6, compounds that circulate in the blood due to inflammation.
Hopkins researchers have created a biosensor that allows them to see multiple, real-time chemical reactions in living cells. The sensor can locate where an enzyme is being turned on or off within the cell, providing valuable insights into how chemicals interact with enzymes.
Researchers from Jackson Laboratory found that high BMI is not directly associated with a high percentage of fat, suggesting the need for more refined measurements to distinguish between large body mass and true obesity. The study's results have implications for understanding the complex interplay of genetic factors in health disorders.
A cohort of over 138,000 adults in Denmark found that those living alone have a twofold increased risk of severe angina and heart attack. Poor education, pension, age, and social isolation are key factors contributing to this increased risk.
A study of over 3600 adults found that narrower arterioles and wider venules were associated with increased risk of coronary heart disease. The results suggest that retinal photography may be a useful non-invasive method for assessing this risk, particularly in women.
Recent study finds that screening levels of C-reactive protein and other compounds do not improve prediction of coronary heart disease risk. Major traditional risk factors, such as age, blood pressure, and cholesterol levels, remain the most accurate predictors of CHD.
A large study found that measuring C-Reactive Protein (CRP) and other novel risk markers does not improve the assessment of future coronary heart disease risk. The study, which followed over 15,000 adults, suggests that standard risk factors such as age, cholesterol levels, and blood pressure remain the most accurate indicators.
A recent study reveals that prion disease infectivity can cause heart damage in mice, with similarities to human amyloid heart disease. The findings have significant implications for the development of new diagnostic tests and treatments for prion diseases.
A 16-week trial found that transcendental meditation significantly lowered blood pressure, improved insulin levels, and enhanced autonomic nervous system functioning. These effects occurred without changes in body weight or medication usage, suggesting a potential new target for treating coronary heart disease prevention.
A new calculator tool, ETHRISK, has been developed to better assess the risk of heart disease in British black and minority ethnic groups. The tool is based on a re-calibration of the Framingham risk equations and provides more realistic assessments of heart disease risks within a 10-year period.
A new study has compared national, European, and US recommendations for statin treatment in British men to prevent cardiovascular disease. The research found that the UK's National Health Service Framework makes the least effective use of available evidence on prevention.
UC Davis researchers found that apple extract protects cells from damage and death by interfering with cellular communication. The study reveals a molecular mechanism for the antioxidant effects of flavonoids in apples, distinct from other fruits like grapes.
A research team at the University of Central Florida has discovered a new protein called MCPIP that increases in levels as blood vessels become inflamed and heart disease develops. The formation of MCPIP leads to cell death, making it a potential target for treatments.
Researchers found that Caucasians with the K55R polymorphism had an accelerated breakdown of beneficial fatty acids called EETs, which play a protective role in the cardiovascular system. This increase in EET degradation is associated with higher coronary heart disease risk.
A recent study published in Heart Rhythm found that smokers are at a markedly increased risk of receiving an electrical discharge from their implantable cardioverter-defibrillators (ICDs). This risk is seven times higher than that of non-smokers, highlighting the importance of quitting smoking for patients with heart disease.
Researchers found less improvement in cardiovascular disease (CVD) mortality among women and the elderly, with a shift towards other forms of CVD. Out-of-hospital deaths have not dropped as much as in-hospital deaths. The study suggests opportunities for improved prevention and interventions to address these disparities.
Dr. Jin's study focuses on the role of oxidative stress in atherosclerosis, a process that speeds up hardening of arteries in Type 2 diabetes patients. His research may lead to new drugs preventing cardiovascular disease in diabetic patients.
A study comparing health outcomes in US and English citizens reveals that Americans are much sicker than their English counterparts. The SES-health gradient appears equally strong in both self-reports and biological measures of health.
A recent study comparing the health of middle-aged Americans and English counterparts found that Americans reported significantly higher levels of diabetes, hypertension, and heart disease. The research suggests that differences in healthcare systems, social programs, and economic factors may contribute to these disparities.
Researchers found patients with NAFLD had an increased risk of heart disease, particularly among women. Elevated ALT activity in the absence of viral hepatitis or excessive alcohol consumption is most commonly due to NAFLD and associated with an increased risk of coronary heart disease.
Researchers believe blocking EC system receptors can reduce cardiometabolic risk and prevent heart disease. The discovery of the EC system holds promise for a new approach to treating obesity and related conditions.
A Swedish study reveals that men and women with a maternal history of coronary heart disease (CHD) are at higher risk of developing the condition. The research found that 55% of men and 43% of women with a maternal CHD history developed CHD, compared to those with no family history.
A new study found that patients who saw visual proof of plaque buildup after an EBT scan were more likely to comply with prescribed statin therapy, exceeding 90% compliance. The study also suggests that this method can improve overall health behaviors beyond just medication adherence.
Researchers identified a gene variant that protects against type 2 diabetes, heart disease, and hypertriglyceridemia. The T-87C variant was found to lower triglyceride levels by 12% and reduce heart disease risk by 34%, offering potential therapeutic targets.
Researchers challenge widely accepted opinion on probucol's protective effect against heart disease, revealing that a different part of the molecule is responsible for its benefits. The study also found no relationship between oxidized cholesterol and heart disease severity.
Researchers at Medical College of Wisconsin discovered that high levels of endothelial-derived microparticles inhibit growth and migration of endothelial cells in the mitral valve tissue. This finding may help prevent endothelial injury in valvular disease and other forms of heart disease.
A new study found that high good cholesterol levels (HDL) are a strong predictor of reduced heart attack risk, while low bad cholesterol levels (LDL) are not. The researchers suggest that current guidelines should focus on both HDL and LDL cholesterol levels.
A study published in Annals of Internal Medicine found that participants who made multiple lifestyle changes, such as improving their diet and increasing physical activity, had a greater reduction in high blood pressure than those who did not make any changes. The intervention group that followed the DASH eating plan saw the most signi...
The Jackson center aims to understand how genes interact to develop healthy individuals or lead to diseases, leveraging the power of the mouse model. Collaborators will use computational approaches to identify clusters of genes associated with complex diseases, shedding light on their evolution and causes.
A new meta-analysis of 54 studies found no clear link between moderate drinking and reduced risk of premature death from all causes. The analysis controlled for age and illness effects that skewed previous findings, suggesting that moderate drinking may not be as protective as thought. Further research is needed to confirm these results.
Scientists have identified specific DNA fragments in tomatoes that influence their nutritional content and taste. By analyzing these fragments, researchers can develop targeted breeding strategies to create healthier and tastier tomatoes.
A recent study found that low levels of LDL cholesterol, even in individuals with high-risk factors, can dramatically reduce the incidence of coronary events. The analysis identified three forms of a gene known as PCSK9 associated with significant reductions in plasma levels of LDL cholesterol.
A new study found that genetic variations lowering LDL cholesterol levels can significantly reduce coronary heart disease risk. People with these variations were eight times less likely to develop heart disease than those without them.
A new study published in JAMA found that women are at a higher risk of developing angina, a symptom of chest pain or discomfort due to insufficient oxygen supply to the heart muscle. Women with angina and diabetes are particularly at risk of experiencing high rates of death from heart disease
A recent study aims to improve diagnosis and treatment of cardiovascular disease through a better understanding of blood flow. Vlachos' research focuses on the physics of blood flow through the body, with an emphasis on experimental models and optical imaging tools.
The UK Biobank project is a revolutionary research undertaking that will gather and store vast amounts of medical data from 40,000 to 69-year-old volunteers. Researchers hope to identify more reliable reasons for why some people develop specific diseases and others do not.