Articles tagged with Heart Disease
Researchers found that patients with severe periodontitis have elevated levels of small-dense LDL in their blood, which increases the risk of heart disease. The study also suggests that platelet activating factor acetylhydrolase may play a role in this increased risk.
A team of scientists has identified the responsible gene, MMACHC, for a rare and devastating genetic disease. The discovery enables the development of early diagnosis and carrier assessment tests, improving the lives of those afflicted with the disease.
A study published in the American Journal of Medicine found that women with similar levels of heart disease as men reported milder symptoms and perceived their disease as severe less often. Researchers suggest this may contribute to differences in heart care delivery between genders.
Studies found that depressed heart patients are more likely to miss medication doses, with 14% of depressed patients not taking their meds as prescribed. Elevated stress hormones also linked to depression in heart disease patients.
A German study of 37 men and 18 women found that some riders experienced increased heart rates that could lead to arrhythmias, especially in those with high blood pressure or previous heart attacks. Researchers suggest operators have external defibrillators on hand for safety.
Researchers found that replacing carbohydrates with protein and unsaturated fat can lower blood pressure, improve cholesterol levels, and reduce the risk of heart disease. The OmniHeart study suggests that these modifications can be effective in reducing some risk factors and estimated risk for heart disease.
The IDEAL study found that intensive LDL-C lowering therapy in patients with previous myocardial infarction did not significantly reduce primary end points but showed reduced risk of secondary composite endpoints and nonfatal acute MI. No differences were observed in cardiovascular or all-cause mortality.
A new study from Johns Hopkins Medicine found that replacing carbohydrates with protein-rich foods or monounsaturated fats reduces the risk of heart disease. The study, which lasted three years, involved 164 healthy adults who followed one of three diets: high in carbohydrate, high in protein, or high in monounsaturated fat.
The Oxford Vascular Study found that cerebrovascular events occurred at similar ages to coronary vascular events, but stroke was more likely to cause major disability. Stroke has a greater clinical burden than heart disease in the UK due to higher rates of acute events and major disability.
Dr. Shiriki Kumanyika has won the first-ever American Heart Association Population Research Prize and the 2005 Dr. Herbert W. Nickens Epidemiology Award from the Association of Black Cardiologists, Inc., for her tireless efforts in preventing heart disease, stroke, and related disorders.
A population study of over 3,000 adults found that hostility does not affect long-term heart health in women, unlike men. Men with high hostility scores were twice as likely to experience recurrent heart disease events.
A Stanford study found that only 33% of high-risk patients received aspirin therapy in 2003, despite conclusive evidence of its benefits. Meanwhile, physicians are increasingly prioritizing pricey statins over aspirin due to heavy marketing.
Dr. Robbins' research focuses on understanding the cellular functions of the heart and identifying genes associated with heart disease. He has developed genetically modified laboratory models to study the connection between protein mutations and heart disease.
The red kiwi has been found to have a promising nutritional profile, making it a potential addition to the diet for its high antioxidant content and low calorie count. The fruit's vibrant red color is also attributed to the presence of anthocyanins, which have been linked to several health benefits.
A recent study published in JAMA found that children with neurological and neuromuscular diseases are at a higher risk of developing respiratory failure from the flu. The study recommends annual influenza vaccination for these children to prevent serious complications.
A study by the University of Bristol found that socio-economically deprived individuals are less likely to receive cholesterol and blood pressure-lowering treatment. The Framingham score, used to identify high-risk patients, was shown to underestimate risk in these groups, resulting in inadequate preventive treatments.
Researchers analyzed human genome variation in various populations to understand disease susceptibility, reproductive success and genetic disorders. Gene conversion played a critical role in shaping the genetic diversity of the Luteinizing Hormone/Chorionic Gonadotropin Beta cluster, which is associated with pregnancy success.
The HapMap project provides detailed information on genetic variations common in human populations, shedding light on the relationship between gene changes and diseases. Researchers have identified key sites of DNA recombination that may hold clues to understanding various conditions.
A large-scale study found a significant inverse association between time spent walking and risk of ischemic stroke, as well as an inverse relationship between sports participation and coronary heart disease risk in Asian countries. Regular physical activity was associated with reduced risk of cardiovascular disease mortality.
The Human HapMap project provides a powerful tool for exploring the root causes of common diseases. By mapping genetic variation across the entire genome, researchers can identify genetic contributions to diseases such as diabetes, cancer, and Alzheimer's disease more efficiently.
A study found that employees who perceived a high level of justice at work had a 30% lower risk of developing coronary heart disease. The association was independent of other risk factors, including job strain and effort-reward imbalance.
Researchers found elevated C-reactive protein levels frequently accompanied traditional heart disease risk factors like smoking, obesity, and high blood pressure. High CRP levels were more common among those with at least one risk factor for heart disease.
Steroid treatment has been shown to reduce inflammation of the heart blood vessels by half in children with Kawasaki's disease. The use of steroids combined with aspirin and IVGB significantly decreases the risk of developing serious complications. Most children recover fully from Kawasaki's disease, which is treatable.
Researchers found that smokers had a significantly higher incidence of developing diabetes compared to non-smokers, even after adjusting for other risk factors. The study suggests another poor health outcome associated with cigarette smoking, supporting current surgeon general's warnings.
A study by John Scott found that the mAKAP signaling system is perturbed in cases of heart disease, leading to cardiomyocyte hypertrophy. Researchers have identified a potential therapeutic target for treating this condition by suppressing the enzyme phosphodiesterase with drugs such as growth hormone.
A large cohort study found a significant association between panic disorder and an increased risk of coronary heart disease. The study, which analyzed data from nearly 40,000 patients, suggests that cardiologists and internists should monitor patients with panic disorder to reduce the risk of cardiovascular disease.
Researchers highlight the importance of raising HDL cholesterol levels, citing a link between higher levels and lower risk of fatal heart attacks. They recommend lifestyle modifications such as regular exercise, weight control, and dietary changes to boost HDL levels, and discuss the benefits and potential risks of drug therapy.
A University of Southern California-led study found that air pollution poses a greater danger to health than previously thought, with a two- to three-fold increase in chronic health effects compared to earlier estimates. The study revealed a significant link between fine particle levels and increased risk of death from heart disease, l...
A survey of 40 hospitals found that high-fat foods contribute to the risk of heart disease among staff and visitors. In contrast, healthier options featuring vegetables, beans, and whole grains are shown to support overall health and well-being.
According to American College of Cardiology guidelines, several factors increase cardiovascular risk, including obesity, physical inactivity, smoking, elevated blood pressure, and diabetes. World Heart Day promotes awareness of these risks and encourages individuals to adopt healthy habits such as regular exercise, balanced diet, and q...
A study analyzing 13,000 Scottish individuals found that excluding deprivation from heart disease risk scoring can exacerbate social gradients in disease. The researchers call for guidelines to be adjusted to take account of deprivation, potentially saving thousands of lives.
Cardiac stress testing reveals a significant association between exercise capacity and heart rate recovery with CHD mortality rates. The study found that asymptomatic individuals with below-average test scores were two to four times more likely to die from CHD within 10-20 years.
A study of over 16,000 participants found a graded association between high blood glucose levels and increasing coronary heart disease risk. Non-diabetic individuals with elevated HbA1c levels were at significantly increased risk of heart disease.
A review by Devereaux and colleagues highlights the risks of non-cardiac surgery, with 500,000 to 900,000 patients experiencing cardiac events each year. The authors discuss methods for estimating risk pre-operatively and communicating these findings to clinicians.
The study evaluates the feasibility and effectiveness of continuous telemonitoring of multiple disease-relevant parameters in patients with chronic heart failure. The results show that treatment can be adjusted before deterioration, leading to a gain in feeling of security and reduced hospital re-admissions.
A study monitored 2640 competitive athletes with arrhythmias, finding that 62 reported cardiac arrests and 38 were resuscitated. Illicit drugs, particularly anabolic steroids, increase the risk of lethal arrhythmias in athletes. Monitoring and treatment are crucial for young athletes and elite competitors.
A telemonitoring system tracks patients' vital parameters at home, enabling early detection of hemodynamic imbalance and prompt intervention. The study found improved health outcomes and reduced hospital re-admissions in patients with chronic heart failure.
A study of 3779 patients found women were 20% less likely to undergo an exercise test or angiography due to suspected coronary obstruction. Despite proven coronary disease, women received less aggressive treatment and were twice as likely to die or suffer a heart attack compared to men.
Researchers found that physical fitness reduces cardiovascular disease death risk by over 50% across all cholesterol levels. The study analyzed data from 19,125 men aged 20-79 and confirmed the effectiveness of revised guidelines for lowering bad cholesterol.
Researchers found that exercising regularly, eating a high-quality diet and maintaining a normal weight can reduce the risk of periodontitis by up to 40%. These healthy behaviors also contribute to lowering diabetes risk factors. Regular monitoring and promotion of these habits by oral health professionals can help prevent gum disease.
Researchers at the Mayo Clinic have discovered that measuring C-reactive protein levels can help identify patients with stiffened arteries, which increases the risk of heart attack and stroke. The study suggests that suppressing low-grade inflammation may be a potential target for improving arterial health.
A new study finds that ethnic minorities in Scotland experience a 60-70% higher incidence of heart attacks compared to non-South Asians. Poorer socio-economic status, environmental factors, barriers to healthcare, and genetic factors contribute to these disparities.
Researchers aim to investigate whether starting hormone therapy early can prevent atherosclerosis and heart attacks. The KEEPS trial, led by Yale University, seeks healthy women aged 42-58 for a double-blind study exploring the effects of early menopausal hormone therapy.
Researchers have discovered a novel probucol-analog that effectively protects against atherosclerosis without the same side effects as its predecessor. This breakthrough compound induces an anti-oxidative and anti-inflammatory pathway in blood vessel walls, offering new hope for treating people with or at risk of heart disease.
Research shows that cocoa's flavinoids can inhibit platelet function, potentially preventing coronary heart disease. In contrast, people with non-O blood types are at increased risk of deep vein thrombosis (DVT), particularly those carrying the Factor V Leiden variant protein.
A study by UT Southwestern researchers found significant differences in C-reactive protein levels among men and women, as well as between black and white patients. Women typically had higher CRP levels than men, while blacks had higher levels than whites, with a notable disparity in cardiovascular disease rates.
Researchers found that estrogen triggers molecular activity blocking cardiac hypertrophy, a common cause of heart enlargement and heart failure. The study suggests that estrogen supplements may prevent cardiac hypertrophy in postmenopausal women, continuing a debate on the hormone's role in limiting cardiovascular disease.
Researchers found that all relatives with aortic valve disease had mutations in the NOTCH1 gene, leading to early developmental defects. The study suggests that targeting these mutations could prevent calcification and slow disease progression, offering potential therapeutic avenues for patients at risk.
Researchers used a new microarray technology to analyze the genes of healthy and diseased dogs, identifying 167 genes that may play a role in canine dilated cardiomyopathy. The study sheds light on the heart's response to disease and offers hope for future treatments.
A new study by Stanford researchers found that gastric bypass surgery significantly improves cardiovascular risk factors, including triglycerides and C-reactive protein levels. The procedure lowers these risks by up to 50%, even beyond what would be expected from weight loss alone.
Researchers found that Scots are more likely to have poorer economic situations, drink problems, and smoke more than English people. Despite controlling for these factors, the study revealed a 50% higher heart disease rate in Scotland compared to England.
Researchers used SPECT imaging to evaluate the effectiveness of stem cell therapy in patients with coronary heart disease. The study found that stem cells improved damaged heart function, surpassing improvements from increased blood flow to the affected area.
Researchers found that variations in four genes controlling inflammation are associated with insulin resistance in Mexican Americans. These findings may enable physicians to identify patients at high risk for developing diabetes and design therapies targeting these genes.
Research by Dr Amy Ferketich and Dr Philip Binkley found that men and women with heart disease in the US experience high levels of psychological distress, with only a third seeking mental health support. The study analyzed data from over 17,000 individuals with different forms of heart disease, highlighting the need for clinicians to c...
A study by researchers at Duke University Medical Center found that improved disease knowledge alone does not translate into improved blood sugar control, cholesterol levels, weight management, or mortality rates among diabetics. Despite this, education is still an important aspect of diabetes care.
Researchers found a significant gap in statin use among patients with high and moderate risk of heart disease. Statin therapy was underused in these groups, with fewer than half of patient visits associated with use, despite being recommended for them.
Researchers found that COX-2 inhibitors can lead to increased cardiovascular risk through vascular remodeling and blood pressure changes. The study suggests that shutting down prostacyclin, a protective fat produced by COX-2, may accelerate atherosclerosis and hardening of the arteries.
Research finds bacteria in subgingival plaques of periodontally diseased individuals are also present in their heart arteries, potentially causing inflammation and increasing heart attack risk. Maintaining good periodontal health is advised to prevent this potential effect.
Researchers found that speaking Spanish, offering health benefits, and addressing community needs are key factors in recruiting Hispanic participants for studies. The study, presented at the American Geriatrics Society meeting, aimed to understand how diseases like diabetes, hypertension, and heart disease affect Hispanics.
A review of studies suggests that a high-energy diet during pregnancy can 'program' an individual's appetite and increase their risk of developing heart disease and diabetes later in life. Rats fed a high-fat diet during pregnancy show abnormalities in their large arteries and kidney function in offspring.