Articles tagged with Heart Disease
Researchers found patients with NAFLD had an increased risk of heart disease, particularly among women. Elevated ALT activity in the absence of viral hepatitis or excessive alcohol consumption is most commonly due to NAFLD and associated with an increased risk of coronary heart disease.
Researchers believe blocking EC system receptors can reduce cardiometabolic risk and prevent heart disease. The discovery of the EC system holds promise for a new approach to treating obesity and related conditions.
A Swedish study reveals that men and women with a maternal history of coronary heart disease (CHD) are at higher risk of developing the condition. The research found that 55% of men and 43% of women with a maternal CHD history developed CHD, compared to those with no family history.
A new study found that patients who saw visual proof of plaque buildup after an EBT scan were more likely to comply with prescribed statin therapy, exceeding 90% compliance. The study also suggests that this method can improve overall health behaviors beyond just medication adherence.
Researchers identified a gene variant that protects against type 2 diabetes, heart disease, and hypertriglyceridemia. The T-87C variant was found to lower triglyceride levels by 12% and reduce heart disease risk by 34%, offering potential therapeutic targets.
Researchers challenge widely accepted opinion on probucol's protective effect against heart disease, revealing that a different part of the molecule is responsible for its benefits. The study also found no relationship between oxidized cholesterol and heart disease severity.
Researchers at Medical College of Wisconsin discovered that high levels of endothelial-derived microparticles inhibit growth and migration of endothelial cells in the mitral valve tissue. This finding may help prevent endothelial injury in valvular disease and other forms of heart disease.
A new study found that high good cholesterol levels (HDL) are a strong predictor of reduced heart attack risk, while low bad cholesterol levels (LDL) are not. The researchers suggest that current guidelines should focus on both HDL and LDL cholesterol levels.
A study published in Annals of Internal Medicine found that participants who made multiple lifestyle changes, such as improving their diet and increasing physical activity, had a greater reduction in high blood pressure than those who did not make any changes. The intervention group that followed the DASH eating plan saw the most signi...
The Jackson center aims to understand how genes interact to develop healthy individuals or lead to diseases, leveraging the power of the mouse model. Collaborators will use computational approaches to identify clusters of genes associated with complex diseases, shedding light on their evolution and causes.
A new meta-analysis of 54 studies found no clear link between moderate drinking and reduced risk of premature death from all causes. The analysis controlled for age and illness effects that skewed previous findings, suggesting that moderate drinking may not be as protective as thought. Further research is needed to confirm these results.
Scientists have identified specific DNA fragments in tomatoes that influence their nutritional content and taste. By analyzing these fragments, researchers can develop targeted breeding strategies to create healthier and tastier tomatoes.
A recent study found that low levels of LDL cholesterol, even in individuals with high-risk factors, can dramatically reduce the incidence of coronary events. The analysis identified three forms of a gene known as PCSK9 associated with significant reductions in plasma levels of LDL cholesterol.
A new study found that genetic variations lowering LDL cholesterol levels can significantly reduce coronary heart disease risk. People with these variations were eight times less likely to develop heart disease than those without them.
A new study published in JAMA found that women are at a higher risk of developing angina, a symptom of chest pain or discomfort due to insufficient oxygen supply to the heart muscle. Women with angina and diabetes are particularly at risk of experiencing high rates of death from heart disease
A recent study aims to improve diagnosis and treatment of cardiovascular disease through a better understanding of blood flow. Vlachos' research focuses on the physics of blood flow through the body, with an emphasis on experimental models and optical imaging tools.
The UK Biobank project is a revolutionary research undertaking that will gather and store vast amounts of medical data from 40,000 to 69-year-old volunteers. Researchers hope to identify more reliable reasons for why some people develop specific diseases and others do not.
Researchers have uncovered a complex network of how one bad guy regulates another bad guy, finding a key peptide hormone called angiotensin controls the expression of an important part of PDGF. This discovery could lead to specific inhibitors of growth factor production to reduce the incidence of common vascular disorders.
A study found that inner city and rural patients who used a telemedicine system significantly reduced their cardiovascular disease risk factors over eight months. Participants showed significant reductions in blood pressure, body mass index, and overall heart disease risk.
Researchers found significant and long-lasting heart benefits for bariatric surgery, including improved body weight, lipid levels, blood pressure, and fasting glucose. The study estimated that the surgery could prevent 16 cardiovascular events and 4 overall deaths per 100 patients compared to the control group.
A new study suggests that aspirin is beneficial for preventing heart attacks and events in men at 5-10% coronary heart disease risk. The therapy also becomes cost-effective when combined with statins for high-risk patients.
Researchers found that low serotonergic function was associated with thicker carotid arteries, suggesting a link between the serotonin system and atherosclerosis. The study's findings could lead to new avenues for preventing heart disease and stroke through the regulation of brain chemistry.
A community-wide health program in Limburg, Netherlands, reduced the worsening of health status among residents aged 25-70, particularly for BMI and waist circumference. The study found significant differences in systolic blood pressure between the intervention group and a control group.
The US Surgeon General has launched a new, free, Web-based tool called My Family Health Portrait to help Spanish-speaking families organize their health histories. The tool provides a graphic printout that organizes information into a diagram or chart, which can be shared with healthcare professionals.
A recent study published in Diabetes reveals that diabetes rates in the US have increased dramatically over the past decade, leading to a sharp rise in hospitalizations and deaths from coronary heart disease. As a result, progress made in reducing illnesses and deaths from this condition may be put at risk.
Scientists have identified two blood clotting genes associated with an increased risk of coronary disease, finding that genetic variants of factor V and prothrombin increase thrombin production. The study suggests the need for bigger studies to identify other genetic causes of heart attacks.
Research suggests a connection between periodontal disease and atherosclerosis, which may be driven by bacteria from gum infections entering the bloodstream. This study emphasizes the importance of managing both oral health and cardiovascular risk factors to reduce overall disease risk.
A study by Yale University researchers found that caspase 3 and caspase 7 are crucial for apoptosis, a process essential for embryonic development and immune system function. Mice lacking these proteins died within the first day of life due to defective cardiac development.
Researchers found patients with rheumatoid arthritis have a three-fold increase in carotid artery atherosclerosis compared to those without RA. Statins and b-blockers may also affect coronary heart disease severity, while hospital volume doesn't correlate with pneumonia care quality.
A landmark study by Harvard Medical School found that spousal illness significantly elevates a partner's mortality risk, particularly within the first two years. The study also revealed specific illnesses have varying effects on partners' health, with dementia and heart disease being most detrimental.
A new study found that eating one grapefruit daily can lower blood lipid levels in patients with hyperlipidemia, reducing the risk of heart disease. Grapefruit's antioxidant action is believed to be beneficial for cardiovascular health.
Frank LaFerla, a UCI neurobiologist, has made significant strides in understanding the molecular development of Alzheimer's disease. His work identified beta amyloid and its buildup as the trigger that marks the onset of memory decline, contradicting previous beliefs.
The NIH has launched two initiatives to identify the genetic and environmental underpinnings of common illnesses. The Genes and Environment Initiative will combine genetic analysis and environmental technology development, while a public-private partnership called GAIN will accelerate genome association studies with $5 million from Pfi...
A low-fat diet was associated with a 15% reduction in estradiol levels and a 30% risk reduction for a certain subtype of breast cancer. The study also found no significant impact on heart disease, but trends toward reduction were seen among women who made the greatest reduction in saturated fat and trans fat consumption.
A recent study found that reducing total dietary fat had no impact on the risk of breast cancer, colon cancer, heart disease, or stroke. Researchers believe that focusing on the types of fats consumed, rather than just reducing total fat, is crucial for disease prevention.
A recent study published in JAMA Network found that a low-fat diet did not significantly decrease the risk of cardiovascular disease or stroke. However, trends toward greater reductions in CHD risk were observed in those with lower intakes of saturated fat or trans fat, or higher intakes of vegetables and fruits.
A study of nearly 49,000 postmenopausal women found a modest reduction in breast cancer incidence among those with high fat intake, but this benefit was not seen in those who reduced their fat intake. Women should focus on reducing saturated and trans fats, increasing vegetable consumption, and maintaining regular exercise for overall ...
A new study has found that high blood pressure and kidney disease increase the risk for heart disease and stroke in older Americans. Patients with moderate chronic kidney disease had a 38% greater chance of developing heart disease than those with normal kidney function.
A recent study published in the Journal of General Internal Medicine found that nearly 10 million more adults have high LDL-C (
The Generation Scotland project is a multi-million pound initiative that will follow the health of 50,000 Scots family members over the next generation. The study aims to explore the causes of common diseases and identify those at high risk of developing genetic conditions.
Grande-Allen's team aims to identify specific drug therapies for patients with valve disease by recreating conditions such as neurohormone buildup and serotonin levels. The bioreactor will simulate mechanical stimulation and fluid movements found inside a living heart.
A recent study has found that a specific genetic variation, ALDH2*2, is responsible for the reduced effectiveness of nitroglycerin in Asian populations. This variation affects the enzyme aldehyde dehydrogenase-2 (ALDH2), which plays a crucial role in metabolizing nitroglycerin.
Studies found that erectile dysfunction is common among men and associated with various chronic diseases, including heart disease. The condition was also linked to increased risk of future cardiovascular events, diabetes, and hypertension.
Researchers at Duke University Medical Center have developed a method to visualize the heartbeat of fruit flies, enabling them to identify genetic mutations associated with human heart disease. The team inserted a mutated gene into the fly genome and observed its effects, revealing similarities with human dilated cardiomyopathy.
The UK Biobank project and the American National Human Genome Research Institute project will gather information to study the interaction between genes and environment over time. The studies aim to identify new treatments for diseases such as cancer and heart disease, but critics raise concerns about privacy and data reliability.
A four-year study of designer rats with high blood pressure and healthy counterparts has identified candidate genes that may contribute to cardiovascular disease. The online database TREX is now available to researchers worldwide, offering an unprecedented amount of data to mine.
A Northwestern University study found that middle-aged individuals with higher body mass indexes had significantly higher risks of hospitalizations for and deaths from heart disease and diabetes in older age. Having a normal BMI in young adulthood and middle age confers significant health benefits.
Ferriprox has been shown to provide significantly better cardio-protection compared to deferoxamine, reducing heart iron concentrations and improving cardiac function in thalassemia patients. The study findings suggest that Ferriprox's small structure provides a greater potential to chelate intracellular iron in the heart.
Researchers found that mice fed a soy-based diet had significantly worse heart problems than those on a milk protein-based diet. This is the first study to show an environmental influence can affect the heart.
Researchers found that a soy-based diet caused significant growth in the hearts of male mice, whereas female mice showed no such effect. The study suggests that phytoestrogens may play a role in exacerbating heart disease, particularly in males.
Researchers found that treating severe gum disease can lower systemic inflammatory markers associated with cardiovascular risk, suggesting a potential link between gum disease and heart health. The study suggests improving periodontal health could significantly reduce the risk of cardiovascular disease.
A study by CU-Boulder researchers found that male mice with hypertrophic cardiomyopathy developed enlarged hearts and heart failure on a soy diet, but not female mice. The team hypothesized that plant-based estrogens in the soy diet triggered biochemical reactions leading to programmed cell death in the heart.
The new JBS 2 guidelines focus on cardiovascular disease as a whole, including those with hardened arteries and diabetes. Screening is recommended for adults at high risk of cardiovascular disease, with targets set for blood pressure, cholesterol, and sugar levels.
A recent study found that African-Americans are more likely to develop arterial leg disease, a condition that can lead to amputation if left untreated. Cigarette smoking is the single most important risk factor for the disease, which is also associated with hypertension, diabetes, and high cholesterol levels.
Researchers analyzed data from over 41,000 adults and found a significant association between tooth loss and heart disease, even among those who had never smoked. The study highlights the importance of promoting good oral health to prevent cardiovascular disease.
A Swedish study found that patients diagnosed with depression were 1.5 times more likely to develop coronary heart disease than those without depression. Young adults between 25-39 years old had an even higher risk of developing CHD, with a ratio of 3.
A recent study found that traditional risk-factor scoring misses one-third of women vulnerable to coronary heart disease, highlighting the need for additional screening methods. Cardiac CT scans are recommended for certain groups of women based on their Framingham Risk Estimate and calcium scores.
A study comparing the genomes of boxers and poodles identified significant genetic variations that could be used to study diseases, development, and behaviors in dogs. The research also sheds light on evolutionary influences shaping mammalian genomes.
The new guidelines provide a concise diagnostic and treatment guide for patients with PAD. They emphasize the importance of early detection and treatment, recommending specific questions, clinical clues, and therapeutic choices to maintain functional independence and decrease the risk of heart attack, stroke, and death.
Research in monkeys shows that stress in younger years can lead to reduced estrogen levels and increased risk of heart disease later in life. Perimenopause is a critical time for cardiovascular health, and starting hormone therapy earlier may be more effective than waiting until menopause.