Researchers at Duke University developed a new molecular 'fishing' technique using atomic force microscopy, allowing for fast and precise measurement of chemical concentrations. The method could be adapted for various chemicals and made faster by parallel testing.
A new study published by the American Academy of Neurology found that people with 'benign MS' for 10 years are at risk of disease progression after 20 years. After 20 years, nearly half of those with benign MS had progressed to a point where they needed a cane to walk.
Researchers found lower concentrations of VOCs in breast milk than in indoor air, with toluene levels ranking highest. This suggests that reducing indoor air pollution is crucial for minimizing infant exposure to harmful chemicals.
Researchers found that men with Primary Progressive Aphasia (PPA) had a higher rate of vasectomy than those without the condition. PPA is a neurological disease causing language problems, while frontotemporal dementia (FTD) affects personality and behavior. The study suggests a possible link between vasectomy and increased risk of thes...
A group setting exposes individuals to brand information, making them forget competitors and their own preferences. The study found a stronger effect on familiar brands, where the exposure to other group members' mentions amplifies the disruption.
A landmark Carnegie Mellon University study found that people who know they are addicted to drugs tend to underestimate the intensity of their cravings. This underestimation can lead to a higher willingness to take risks and engage in behaviors that increase the likelihood of relapse. The study suggests that teaching individuals to ant...
The exclusivity of clinical trial data could jeopardize efforts to create generic versions of life-saving medicines, harming public health. Karin Timmermans warns that data exclusivity can delay generic competition and drive up prices.
A groundbreaking study at UCSF Children's Hospital aims to correct pectus excavatum, a congenital chest deformity, using a magnetic procedure. The 3MP technique uses magnets to gradually realign the breastbone and chest wall, offering a potential alternative to invasive surgery.
Purdue University researchers use dendrimers to label specific proteins in living cells, allowing them to determine protein functions and diagnose diseases. This new method provides a more reliable alternative to existing methods, which require small sample amounts and damage the natural environment.
A new medical technique using microsecond electrical pulses has been shown to create permanent nanoscale holes in target cell membranes without harming surrounding tissue. This technique, called irreversible electroporation (IRE), has the potential to revolutionize minimally invasive surgical treatments for tumors.
A recent study by Alexander Chernev reveals that consumers perceive specialized products to be superior on a single attribute, even when the description is the same. This 'zero-sum heuristic' suggests that advantages in one area are compensated by disadvantages in another.
A new study by Aparna A. Labroo and Suresh Ramanathan challenges the common assumption that happy endings in advertising are always better. Emotionally involved viewers actually prefer narratives with a negative-to-positive arc, as it allows them to cope with subsequent negativity.
Researchers at Rochester Institute of Technology are developing a micropump to administer drugs and gene-based therapy treatments for auditory dysfunction. The goal is to improve treatment and cure hearing loss, surpassing the limitations of existing hearing aids and cochlear implants.
A stable social structure in badgers can help control the spread of bovine tuberculosis (TB), ecologists have found. The study found that movement of individuals between groups is instrumental in driving disease dynamics at the population level.
A study published in Neurology found that smoking marijuana reduced nerve pain in people with HIV-associated sensory neuropathy by 34%, compared to 17% for those who received a placebo. The study also showed significant relief from chronic pain, with an average reduction of 72%.
The USC researchers have created two novel CMOS architectures for 'biometric radar' and automobile accident avoidance systems. One chip can detect living victims in rubble by analyzing minute movements caused by breathing and heartbeat, while the other uses a low-cost CMOS chip to detect ultrawideband signals.
Researchers are investigating the causes of bone loss in astronauts due to prolonged weightlessness. The study focuses on the role of integrins, which may be key to decreasing bone cell production and preventing fractures.
The program aims to understand the behavior of strongly correlated electrons in materials such as high-temperature superconductors and magnetic materials. Researchers at Rice will combine theoretical and experimental approaches to tackle these complex materials.
A study published in PLoS Medicine found that 20% of Ethiopian patients with TB fail to complete treatment due to factors such as public transport costs and age. The researchers recommend expanding access to treatment centers to improve adherence rates.
Researchers at Yale University developed a method to trap viruses in cells that prevent their reproduction, potentially alleviating disease. By using 'trap cells' with viral binding sites, the virus population declines towards extinction when the number of trap cells exceeds a threshold.
A new paper from the Journal of Consumer Research distinguishes between narrative and analytical self-referencing in ads. Narrative self-reference almost always leads to favorable evaluations, while analytical self-reference can lead to negative responses if the ad's message is not well-reasoned.
A new statistical method helps choose animals that are more congenial in groups, improving productivity and animal well-being. The tool aids in predicting how social interactions impact the natural evolution of species, with potential applications for securing the world's food supply.
Researchers successfully differentiated human neural stem cell grafts into functional neurons in the spinal cord of adult rats, growing axons and forming synapses with motor neurons. However, further studies are needed to determine whether these cells can function correctly and provide benefits for patients.
Researchers found that consumers who didn't understand the joke often preferred clever slogans with multiple meanings. A new scale measures how quickly people grasp additional meanings, showing that degree of understanding has little impact on response.
A study published in PLoS Medicine found that some people have low-titer antibodies against H5N1 influenza, suggesting potential protection. The researchers also observed cross-reactive antibodies in mice, which afforded partial protection against avian H5N1 infection.
Emerging research in breast cancer management includes advanced imaging technologies like 3D mammography and MRI, as well as novel vaccines that stimulate the immune system to attack tumors. This new approach aims to alter current screening and treatment paradigms, improving patient care.
A study published in the Canadian Medical Association Journal found that women having a planned cesarean section are at a significantly higher risk of severe complications. The rate of severe complications was found to be 27.3 per 1000 deliveries for cesarean sections, compared to 9.0 per 1000 deliveries for vaginal deliveries.
A new study found that including protein from lean sources of pork in your diet can help retain more lean body mass, which includes muscle, while losing weight. The study, conducted by Dr. Wayne Campbell and his colleagues, evaluated the weight loss of 46 overweight or obese women who followed one of two reduced-calorie diets.
Saliva-based diagnostic tools are being developed at the University of Texas at Austin to provide non-invasive testing for health issues. Researchers aim to create lab-on-a-chip sensor systems for measuring biomarkers in saliva samples, making clinical tests more accessible and affordable.
A study spanning 25 years found that early attachment experiences influence adult emotional expression and relationship dynamics. Secure infants tend to form closer friendships and express emotions more effectively in adulthood.
Researchers at Rockefeller University have successfully cloned mice from adult skin stem cells using nuclear transfer, with a success rate of 19 out of 100 attempts. This breakthrough could lead to the creation of personalized embryonic stem cell lines for disease research and treatment.
A team of researchers from the University of Georgia has created a working model that explains how biological clocks work at the molecular level. The discovery has significant implications for understanding diseases such as cancer and sleep disorders, which are often linked to clock gene regulation.
Researchers at Rockefeller University have cloned healthy mice from adult stem cells, a breakthrough that could lead to new therapies and treatments. The successful cloning rate was 1.6% when using female skin stem cells, but higher when using male stem cells, opening up potential for future human applications.
A recent study by the University of Missouri-Columbia found that Hispanic male immigrants prioritize traditional family values and 'familismo' when making decisions about family planning. The research recommends using this cultural concept to encourage open communication and safe-sex practices among couples.
A recent study by University of Washington researchers reveals that one negative employee can have a profound impact on the entire team. The researchers found that toxic team members can lead to downward spirals in organizations and create conflict among colleagues.
Patients with Parkinson's disease who develop the condition at a younger age and have a history of alcohol abuse are more likely to experience pathological gambling as a side effect of dopamine agonist medications. Behavioral characteristics such as impulsivity and risk-taking behavior may also play a role in this increased risk.
A new study finds that p38-alpha MAPK inhibits tumor formation by sensing oxidative stress and triggering apoptosis. Cancer cells may evade this mechanism by desensitizing p38-alpha to ROS, highlighting potential therapeutic targets for cancer treatment.
Research on ophthalmic genetics has identified genes associated with retinitis pigmentosa, corneal dystrophies, and other eye diseases, offering insights into heredity and molecular genetics. Collaboration between scientists is expected to answer questions about gene functions and benefit patients
A new analysis confirms the benefit of switching treatment from tamoxifen to an aromatase inhibitor on disease-free survival, with a modest improvement in overall survival for oestrogen-receptor-positive patients. The findings suggest that molecular markers may predict which patients benefit from endocrine treatment strategy.
The study assessed molecular testing's utility in caring for patients with genetic retinal diseases. Molecular testing confirmed a clinical diagnosis of hereditary disorders in 133 out of 266 diagnostic tests, while also identifying carrier status and ruling out familial mutations in asymptomatic individuals.
A new study found that consumers trust recommendations from individuals with shared likes more than those with shared dislikes, attributed to attribute ambiguity. The researchers discovered a positivity effect in agent evaluation, where positive attributes outweigh negative ones.
A novel drug sequence combining tamoxifen and exemestane has been shown to improve breast cancer survival rates in postmenopausal women by 17%, according to a new study. The treatment sequence was found to be safe and well-tolerated, offering hope for improved treatment options for patients worldwide.
New research by Brown University Professor Ross Levine finds that powerful supervisory agencies actually lower bank lending integrity. Instead, strategies focusing on accurate information disclosure enhance efficiency and reduce corruption. The study suggests 90% of countries implementing Basel II regulations may face bad outcomes.
The Smithsonian Tropical Research Institute will expand its research capability with a new Global Earth Observatory system, increasing the quality of scientific data across 20 large-scale research plots in 17 countries. The grant will enable the Center for Tropical Forest Science to compare climate change and forest carbon data.
A new study reveals that breast cancer patients taking tamoxifen who switch to an aromatase inhibitor within three years experience significant improvements in survival rates. The treatment demonstrates a clear survival benefit without an increased risk of death from other causes.
Michigan State University professor Jon Miller is advocating for scientists to take on school board roles to enhance science literacy and educational quality. He believes scientists can bring valuable expertise and strategic thinking to the role, making a significant impact on public schools.
The UH David M. Underwood chapter of the American Humanics program received the Program Excellence Award for achieving excellence in all areas of programming, institutional and community support, effective public relations and fundraising, quality of internships and graduate placement.
A new mouse model of non-small cell lung cancer validates MEK inhibitors as a potential treatment option. The model, developed by Dr. Martin McMahon and colleagues, shows that MEK inhibition can halt tumor progression in early-stage lung tumors.
Scientists have found that nifedipine, commonly used for high blood pressure, can reverse iron overload in mouse models and may treat similar conditions in humans. The compound helps mobilize iron from stores in the liver and enhances its excretion into the urine.
Researchers found that living in more walkable neighborhoods increases a person's chance of walking for exercise, with a 30- to 600-fold increase compared to less walkable areas. This could lead to better health outcomes for older adults struggling with obesity.
The winners of the 2006 AAAS Science Journalism Awards were recognized for their exceptional reporting on Alzheimer's disease, climate change, and innovative research. Stacey Burling won for her compelling story on the life and death of an Alzheimer's patient, while Michelle Nijhuis was honored for her series on climate change in the A...
A Scripps research study reveals the dynamic structural details of single prion molecules, shedding light on normal folding mechanisms and abnormal amyloid fibril conversion. The findings may lead to novel therapeutic targets for neurodegenerative diseases.
A large prospective study suggests that midday napping reduced coronary mortality by about one third among men and women. Researchers found that people who regularly took siestas had a 37% lower coronary mortality than those not taking siestas.
A new study suggests that human males have evolved mechanisms to outcompete rivals for fertilization, even after sex. This phenomenon, dubbed 'sperm competition,' can lead to increased sperm count and more aggressive sexual behavior in response to perceived infidelity.
Scripps research team discovers a chemical pathway that causes mice to overeat and gain weight due to the absence of the EP3 receptor. The study found that mice without the receptors are more active during their normal sleep cycle and eat more, leading to weight increases of up to 30 percent.
The Helios Scholars Program at the Translational Genomics Research Institute (TGen) provides stipend funding and mentorship to 50 qualified students from diverse backgrounds. The eight-week program aims to develop foundational skills in science and prepare students for careers in the field.
A study by Queen Mary College researchers found nearly 40% of doctors in one Russian city had latent TB infection, with rates higher among those working in TB clinics. The study highlights the need for regular occupational health screening to control TB spread and address drug resistance issues.
Researchers found that antipsychotic drugs increase AMPK activity in the brain, triggering increased appetite. Blocking a specific histamine receptor reduces AMPK levels and appetite, offering hope for new, weight-neutral treatments.
A University of Houston student is working on a space suit redesign that prioritizes stability and locomotion for astronauts. Her research focuses on reducing the weight and improving the mobility of the space suit, which will enable astronauts to navigate the lunar terrain more easily.
A new study by Yale University researchers found a link between long-term marijuana smoking and respiratory complications, including obstructive lung disease. The study's findings suggest that patients should be advised of the potential negative impact on overall lung health despite methodological limitations.
Researchers at Duke University have found that lubricin helps reduce friction and maintain joint cartilage integrity, suggesting its potential as a treatment for osteoarthritis. The study used precise measurement of biomechanical properties to compare lubricin-deficient joints to normal ones.
Taking regular midday naps is linked to a lower risk of death from heart disease in Greek adults. Among working men, systematic napping for 30 minutes or more three times a week reduces the risk by 64%.
A large-scale study by Johns Hopkins University found that individuals with genetic conditions are more likely to report being denied health insurance than those with other chronic illnesses. Nearly 60% of participants believed their insurance company could access medical information without permission.
Researchers discover novel mechanism of gene-for-gene resistance in plant immune system, providing insights into enhancing crop yield and combating agricultural losses. The study reveals that the N resistance protein recognizes pathogen Avr proteins through a different region on its Toll-interleukin-1 receptor homology domain.
A recent study found that the extent of brain tissue loss and lesion load at diagnosis can predict the rate of brain atrophy over two years in MS patients. Baseline MRI variables, including brain volume and T2 lesions, are associated with subsequent brain volume change.
Atrial fibrillation affects over 2.2 million US citizens, causing fatigue, shortness of breath, and stroke risk; the new Cox-maze IV procedure offers a simpler alternative to traditional surgery with fewer complications
Researchers developed a simple and accurate two-gene test that distinguishes between gastrointestinal stromal tumor (GIST) and leiomyosarcoma (LMS) with near perfect accuracy. The Top Scoring Pair analysis approach has potential for wider application in individualized diagnosis and treatment of other types of cancer.
Two of Greenland's largest glaciers experienced dramatic fluctuations in melting, dumping twice as much ice into the sea in less than a year before returning to near-normal rates. The sudden changes highlight the need for more accurate computer models to understand glacial behavior and predict future sea level rise.
The Biodesign Institute is working on a $2.67 million NIH grant to develop antidotes for nerve agent poisoning. The project aims to create 'next-generation' bioscavengers using human enzymes and plant-based production methods.
A recent study by JoAndrea Hoegg and Joseph W. Alba found that the color of a drink can significantly affect how it tastes, with tint dominating taste perception over other attributes.
A study found significant disparities in colon cancer screening practices by ethnicity, sex, age, education and income level among Medicare patients. Approximately 18.3% of the sample population had been screened for colon cancer during the study period.
A novel spray drying method has been developed to preserve and deliver the most common tuberculosis (TB) vaccine, promising greater stability at room temperature and use in needle-free delivery. This technique could provide a better approach for vaccination against TB and help prevent the spread of HIV/AIDS in developing countries.
Archaeologists have uncovered stone 'hammers' dating back 4,300 years in the Taï rainforest, used by chimpanzees to crack nuts. The discovery confirms that some of humanity's behavioral hallmarks were inherited from a common ancestor with great apes.
Researchers discovered that people with ambivalent opinions are more susceptible to persuasion from untrustworthy sources. In contrast, individuals with strong views tend to evaluate the credibility of messages before making a decision. The study's findings highlight the influence of others on consumer attitudes.
In a randomized placebo-controlled trial, patients smoking cannabis experienced a 34 percent reduction in intense foot pain associated with HIV—twice the rate experienced by patients who smoked placebo. This study provides evidence for the therapeutic value of cannabis in managing HIV-associated sensory neuropathy.