Researchers at Rockefeller University have cloned healthy mice from adult stem cells, a breakthrough that could lead to new therapies and treatments. The successful cloning rate was 1.6% when using female skin stem cells, but higher when using male stem cells, opening up potential for future human applications.
A recent study by the University of Missouri-Columbia found that Hispanic male immigrants prioritize traditional family values and 'familismo' when making decisions about family planning. The research recommends using this cultural concept to encourage open communication and safe-sex practices among couples.
A recent study by University of Washington researchers reveals that one negative employee can have a profound impact on the entire team. The researchers found that toxic team members can lead to downward spirals in organizations and create conflict among colleagues.
Patients with Parkinson's disease who develop the condition at a younger age and have a history of alcohol abuse are more likely to experience pathological gambling as a side effect of dopamine agonist medications. Behavioral characteristics such as impulsivity and risk-taking behavior may also play a role in this increased risk.
A new study finds that p38-alpha MAPK inhibits tumor formation by sensing oxidative stress and triggering apoptosis. Cancer cells may evade this mechanism by desensitizing p38-alpha to ROS, highlighting potential therapeutic targets for cancer treatment.
Research on ophthalmic genetics has identified genes associated with retinitis pigmentosa, corneal dystrophies, and other eye diseases, offering insights into heredity and molecular genetics. Collaboration between scientists is expected to answer questions about gene functions and benefit patients
A new analysis confirms the benefit of switching treatment from tamoxifen to an aromatase inhibitor on disease-free survival, with a modest improvement in overall survival for oestrogen-receptor-positive patients. The findings suggest that molecular markers may predict which patients benefit from endocrine treatment strategy.
The study assessed molecular testing's utility in caring for patients with genetic retinal diseases. Molecular testing confirmed a clinical diagnosis of hereditary disorders in 133 out of 266 diagnostic tests, while also identifying carrier status and ruling out familial mutations in asymptomatic individuals.
A new study found that consumers trust recommendations from individuals with shared likes more than those with shared dislikes, attributed to attribute ambiguity. The researchers discovered a positivity effect in agent evaluation, where positive attributes outweigh negative ones.
A novel drug sequence combining tamoxifen and exemestane has been shown to improve breast cancer survival rates in postmenopausal women by 17%, according to a new study. The treatment sequence was found to be safe and well-tolerated, offering hope for improved treatment options for patients worldwide.
New research by Brown University Professor Ross Levine finds that powerful supervisory agencies actually lower bank lending integrity. Instead, strategies focusing on accurate information disclosure enhance efficiency and reduce corruption. The study suggests 90% of countries implementing Basel II regulations may face bad outcomes.
The Smithsonian Tropical Research Institute will expand its research capability with a new Global Earth Observatory system, increasing the quality of scientific data across 20 large-scale research plots in 17 countries. The grant will enable the Center for Tropical Forest Science to compare climate change and forest carbon data.
A new study reveals that breast cancer patients taking tamoxifen who switch to an aromatase inhibitor within three years experience significant improvements in survival rates. The treatment demonstrates a clear survival benefit without an increased risk of death from other causes.
Michigan State University professor Jon Miller is advocating for scientists to take on school board roles to enhance science literacy and educational quality. He believes scientists can bring valuable expertise and strategic thinking to the role, making a significant impact on public schools.
The UH David M. Underwood chapter of the American Humanics program received the Program Excellence Award for achieving excellence in all areas of programming, institutional and community support, effective public relations and fundraising, quality of internships and graduate placement.
A new mouse model of non-small cell lung cancer validates MEK inhibitors as a potential treatment option. The model, developed by Dr. Martin McMahon and colleagues, shows that MEK inhibition can halt tumor progression in early-stage lung tumors.
Scientists have found that nifedipine, commonly used for high blood pressure, can reverse iron overload in mouse models and may treat similar conditions in humans. The compound helps mobilize iron from stores in the liver and enhances its excretion into the urine.
Researchers found that living in more walkable neighborhoods increases a person's chance of walking for exercise, with a 30- to 600-fold increase compared to less walkable areas. This could lead to better health outcomes for older adults struggling with obesity.
The winners of the 2006 AAAS Science Journalism Awards were recognized for their exceptional reporting on Alzheimer's disease, climate change, and innovative research. Stacey Burling won for her compelling story on the life and death of an Alzheimer's patient, while Michelle Nijhuis was honored for her series on climate change in the A...
A Scripps research study reveals the dynamic structural details of single prion molecules, shedding light on normal folding mechanisms and abnormal amyloid fibril conversion. The findings may lead to novel therapeutic targets for neurodegenerative diseases.
A large prospective study suggests that midday napping reduced coronary mortality by about one third among men and women. Researchers found that people who regularly took siestas had a 37% lower coronary mortality than those not taking siestas.
A new study suggests that human males have evolved mechanisms to outcompete rivals for fertilization, even after sex. This phenomenon, dubbed 'sperm competition,' can lead to increased sperm count and more aggressive sexual behavior in response to perceived infidelity.
Scripps research team discovers a chemical pathway that causes mice to overeat and gain weight due to the absence of the EP3 receptor. The study found that mice without the receptors are more active during their normal sleep cycle and eat more, leading to weight increases of up to 30 percent.
The Helios Scholars Program at the Translational Genomics Research Institute (TGen) provides stipend funding and mentorship to 50 qualified students from diverse backgrounds. The eight-week program aims to develop foundational skills in science and prepare students for careers in the field.
A study by Queen Mary College researchers found nearly 40% of doctors in one Russian city had latent TB infection, with rates higher among those working in TB clinics. The study highlights the need for regular occupational health screening to control TB spread and address drug resistance issues.
Researchers found that antipsychotic drugs increase AMPK activity in the brain, triggering increased appetite. Blocking a specific histamine receptor reduces AMPK levels and appetite, offering hope for new, weight-neutral treatments.
A University of Houston student is working on a space suit redesign that prioritizes stability and locomotion for astronauts. Her research focuses on reducing the weight and improving the mobility of the space suit, which will enable astronauts to navigate the lunar terrain more easily.
A new study by Yale University researchers found a link between long-term marijuana smoking and respiratory complications, including obstructive lung disease. The study's findings suggest that patients should be advised of the potential negative impact on overall lung health despite methodological limitations.
Researchers at Duke University have found that lubricin helps reduce friction and maintain joint cartilage integrity, suggesting its potential as a treatment for osteoarthritis. The study used precise measurement of biomechanical properties to compare lubricin-deficient joints to normal ones.
Taking regular midday naps is linked to a lower risk of death from heart disease in Greek adults. Among working men, systematic napping for 30 minutes or more three times a week reduces the risk by 64%.
A large-scale study by Johns Hopkins University found that individuals with genetic conditions are more likely to report being denied health insurance than those with other chronic illnesses. Nearly 60% of participants believed their insurance company could access medical information without permission.
Researchers discover novel mechanism of gene-for-gene resistance in plant immune system, providing insights into enhancing crop yield and combating agricultural losses. The study reveals that the N resistance protein recognizes pathogen Avr proteins through a different region on its Toll-interleukin-1 receptor homology domain.
A recent study found that the extent of brain tissue loss and lesion load at diagnosis can predict the rate of brain atrophy over two years in MS patients. Baseline MRI variables, including brain volume and T2 lesions, are associated with subsequent brain volume change.
Atrial fibrillation affects over 2.2 million US citizens, causing fatigue, shortness of breath, and stroke risk; the new Cox-maze IV procedure offers a simpler alternative to traditional surgery with fewer complications
Researchers developed a simple and accurate two-gene test that distinguishes between gastrointestinal stromal tumor (GIST) and leiomyosarcoma (LMS) with near perfect accuracy. The Top Scoring Pair analysis approach has potential for wider application in individualized diagnosis and treatment of other types of cancer.
Two of Greenland's largest glaciers experienced dramatic fluctuations in melting, dumping twice as much ice into the sea in less than a year before returning to near-normal rates. The sudden changes highlight the need for more accurate computer models to understand glacial behavior and predict future sea level rise.
The Biodesign Institute is working on a $2.67 million NIH grant to develop antidotes for nerve agent poisoning. The project aims to create 'next-generation' bioscavengers using human enzymes and plant-based production methods.
A recent study by JoAndrea Hoegg and Joseph W. Alba found that the color of a drink can significantly affect how it tastes, with tint dominating taste perception over other attributes.
A study found significant disparities in colon cancer screening practices by ethnicity, sex, age, education and income level among Medicare patients. Approximately 18.3% of the sample population had been screened for colon cancer during the study period.
A novel spray drying method has been developed to preserve and deliver the most common tuberculosis (TB) vaccine, promising greater stability at room temperature and use in needle-free delivery. This technique could provide a better approach for vaccination against TB and help prevent the spread of HIV/AIDS in developing countries.
Archaeologists have uncovered stone 'hammers' dating back 4,300 years in the Taï rainforest, used by chimpanzees to crack nuts. The discovery confirms that some of humanity's behavioral hallmarks were inherited from a common ancestor with great apes.
Researchers discovered that people with ambivalent opinions are more susceptible to persuasion from untrustworthy sources. In contrast, individuals with strong views tend to evaluate the credibility of messages before making a decision. The study's findings highlight the influence of others on consumer attitudes.
In a randomized placebo-controlled trial, patients smoking cannabis experienced a 34 percent reduction in intense foot pain associated with HIV—twice the rate experienced by patients who smoked placebo. This study provides evidence for the therapeutic value of cannabis in managing HIV-associated sensory neuropathy.
A new technique using ozone preserves grapes while boosting healthy compounds, potentially leading to hypoallergenic wines. The method shows promise for reducing sulphite use in winemaking, which can cause allergic reactions and affect the flavor of wine.
Researchers found that people prefer waiting for monetary rewards over consumable ones due to the constant utility of money. This preference is due to inconstancy of desire for goods like beer, candy, and soda. The study has implications for savings, investments, and decision-making processes.
Researchers found that cortisol can lessen emotional impact of stress in women, with a high dose providing protective effects. The study suggests potential for cortisol as a clinical tool to treat and prevent anxiety disorders.
Researchers warn that an immuno-contraception vaccine, which aims to control wildlife populations, is not fully effective and may manipulate natural reproduction in unpredictable ways. The vaccine also raises concerns about the potential for individuals who survive the vaccine to carry infectious diseases affecting other animals.
Researchers found that green consumers face difficulties deciding which product to buy due to conflicting values and lack of information. The study identifies three types of green consumers: selectors, translators, and exceptors, highlighting the need for practical help and incentives to promote sustainable practices.
Researchers at Stanford University School of Medicine have developed a technique to prevent cleft palates in fetal mice by injecting pregnant mothers with a small molecule. This breakthrough raises hopes that similar vaccination-type techniques may one day be used to prevent many types of human birth defects.
Researchers at Dana-Farber Cancer Institute and Broad Institute develop a practical method for screening tumors for cancer-related gene abnormalities, paving the way for personalized medicine. The technique uses high-throughput genotyping to detect important mutations in oncogenes with high accuracy and sensitivity.
Biologists at Carnegie Institution discover a new way plant cells regulate nutrient uptake through physical interaction between neighboring molecules, applicable across species. The discovery has potential applications from understanding human diseases like kidney function to engineering better crops.
A research team at Northwestern University has identified Bi-2212 as a suitable material for the new wires needed to build a 30 Tesla magnet, a significant improvement over current materials. The findings set a speed limit for high-temperature superconductivity, which could enable powerful magnets without helium cooling requirements.
Pregnant women over 40 years old are at higher risk of stillbirth due to various pregnancy complications. Fetal testing at 38 weeks gestation is most effective in reducing stillbirth rates among older women.
New research funded by the Economic & Social Research Council found that effective early childhood leadership involves distributed responsibility, skill acknowledgment, and a level of maturity within the organization. The study provides a guide for best practice in early childhood education and care.
A. Paul Alivisatos, co-editor of Nano Letters, wins the Ernest Orlando Lawrence Award for his contributions to materials research and development of functional semiconducting nanocrystals, also known as quantum dots.
Researchers develop mechanism for capturing carbon dioxide from power plants and injecting it into the ground, where it will be trapped naturally. The injected gas forms a plume that rises through permeable rock, eventually breaking into small bubbles or blobs that remain safely stored.
Researchers at Yale University discovered a potential reversible cause of first-degree fetal heart block, which impairs the heart's electrical signaling. The PRIDE study found that early treatment with dexamethasone can reverse the condition, but it can progress rapidly to irreversible third-degree block.
A new study from Tufts University found that high folate status and adequate vitamin B12 levels are associated with better cognitive function in seniors. Low vitamin B12 status was linked to increased cognitive impairment, while high serum folate was more detrimental when combined with low vitamin B12.
Researchers at Tufts University have found that while older adults consume more vitamin K than younger adults, many still do not meet the recommended intake. High phylloquinone intake may be associated with better dietary habits and reduced risk of cardiovascular disease, but further research is needed.
Researchers at MIT envision a future where cellulosic ethanol becomes a significant part of the US energy supply due to its abundance and favorable energy balance. Current challenges include improving plant material production per acre and fermentation efficiency.