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American Society for Biochemistry and Molecular Biology


ASBMB to launch Insights in Biochemistry and Molecular Biology, a new broad based journal publishing discoveries across molecular life sciences

The American Society for Biochemistry and Molecular Biology (ASBMB) introduces a new journal, Insights in Biochemistry and Molecular Biology, broadening its scope to cover molecular life science discoveries. The journal joins ASBMB's family of journals with swift publication and constructive review.

Study links long-term consumption of reused deep-fried oil with increased neurodegeneration

Rats consuming reheated sesame or sunflower oil showed increased oxidative stress and inflammation in the liver, leading to significant damage in the colon and changes in endotoxins. The study suggests that long-term deep-fried oil consumption may contribute to neurodegeneration and highlight the need for further research on this topic.

New diagnostic finds intact sperm in infertile men

Researchers developed a noninvasive diagnostic test to identify intact sperm in infertile men with nonobstructive azoospermia. The test uses protein biomarkers AKAP4 and ASPX to visualize well-developed sperm, potentially increasing success rates for surgical sperm extraction. This breakthrough may lead to new male birth control drugs ...

SourceAmerican Society for Biochemistry and Molecular Biology·JournalMolecular & Cellular Proteomics·TypeExperimental study·DateJun 14, 2023

Global analysis of coronavirus protein research reveals how countries respond to disease

A global analysis of coronavirus protein research found that countries with larger economies generated more 3D structure determinations for the protein components of coronaviruses. However, there were many outliers, with some advanced and prosperous countries publishing few or no structures, while others strongly affected by COVID-19 p...

Reimagining drugs for rare brain disorder

A team of researchers has developed a new method to screen FDA-approved drugs to determine if they could be repurposed or improved to help patients with spinocerebellar ataxia type 5 (SCA5), a rare and debilitating disease. The pipeline uses cutting-edge spectroscopy to examine the interaction between mutant β-III-spectrin and actin, i...

SourceAmerican Society for Biochemistry and Molecular Biology·JournalJournal of Biological Chemistry·TypeExperimental study·DateFeb 16, 2023

Harnessing good fats to relieve MS symptoms

A study published in the Journal of Biological Chemistry found that a fish oil derivative called DHEA can reduce inflammation and disease severity in mice with multiple sclerosis. By supplementing the diet of mice with DHEA, researchers noticed a decrease in MS-like disease symptoms and an improvement in the immune system's response.

SourceAmerican Society for Biochemistry and Molecular Biology·JournalJournal of Biological Chemistry·TypeExperimental study·DateFeb 8, 2023

Progesterone from an unexpected source may affect miscarriage risk

A recent study found that disruptions in progesterone signaling between maternal and embryonic tissue may be linked to recurrent miscarriage. The study discovered that migratory cells from the placenta produce enzymes necessary for progesterone production, which are lower in women with a history of recurrent miscarriages.

SourceAmerican Society for Biochemistry and Molecular Biology·JournalJournal of Lipid Research·DateJan 6, 2020