Researchers discovered that shortly after a stroke, macrophages from the blood attack dead and adjacent healthy brain tissue. This process was hindered by inactivating the Cxcr4 gene, which acts like an antenna for inflammatory processes in the brain.
A randomized controlled trial found that T'ai Chi was feasible and acceptable for improving chronic low back pain in adults over 65. High attendance rates and perceived benefits were observed among participants, suggesting a potential treatment option for this population.
Rutgers researchers found young sexual minority men lack knowledge about HPV and its importance. Health care providers often inadequately discuss the virus and vaccine with these patients.
Research finds that sorghum crops in areas with high witchweed prevalence have genetic adaptations to resist the parasite, altering hormone production. While these mutations confer some resistance, they also affect photosynthesis and growth, raising potential trade-offs.
Legal epidemiology examines how law affects disease and injury in a population. Research studies, such as those on community health workers and pregnancy-specific alcohol policies, provide key evidence to inform policy decisions.
Researchers discovered a rare disease called Langerhans cell histiocytosis (LCH) in the fossilized tail of a young dinosaur that lived in Canada 60 million years ago. The study found that the disease has survived for over 60 million years and still affects humans, particularly children under 10.
Two pilot studies reveal changes in brain connectivity related to stress and problem-solving ability, suggesting a biomarker for stress-induced cognitive impairment. The findings, published in Brain Imaging and Behavior and NeuroImage, could ultimately inform treatment strategies for patients suffering from stress-related illnesses.
Two studies found that soft drink taxation and labeling laws led to a decrease in beverage purchases high in sugar, sodium and saturated fat. In Chile, front-of-packaging warning labels reduced consumption by 22.8mL per capita per day, while the UK Soft Drinks Industry Levy increased prices by 31% and resulted in significant reductions...
A novel injectable drug, NOV004, is being developed by Novosteo Inc. to heal broken bones faster and strengthen weak bones. The treatment concentrates at the fracture site while reducing exposure to the rest of the body, potentially reducing mortality rates among older adults.
Physicists have discovered a new phase of motion in ring-shaped polymers under shear, where they 'inflate' and stabilize themselves. This behavior is not seen in other forms of polymers, such as linear chains or stars.
A 16-year German-Egyptian research project has uncovered the history of Asyut's necropolis, revealing over 300 tombs and diverse artworks. The finds have broadened knowledge about the region's cultural and economic boom during the First Intermediate Period and Middle Kingdom.
A digital intervention program called Run4Love, tested on the popular Chinese social media app WeChat, significantly reduced depressive symptoms and stress among people living with HIV. The study found a promising approach to addressing mental health gaps in resource-limited settings.
Researchers used high-resolution microcomputed tomography to study the anatomy of three known specimens of T. marauna, a Neotropical electric fish species. The study revealed characteristics of the fish's bones without requiring dissection, providing new insights into this rare species.
The University of Bristol is working with the Children of the 90s health study to examine the effect of environmental exposures on health. The project aims to develop tools to predict disease risk based on environmental factors and will combine data from multiple studies across Europe.
Scientists have made a breakthrough in understanding the rapid reproduction of the malaria parasite by identifying crucial molecules involved in cell division. This discovery could pave the way for developing novel therapeutic strategies against the disease.
Researchers at Florida State University discovered a fungus that stabilizes key proteins involved in cancer and neurological disease signaling pathways. The natural product fusicoccin has been identified as a tool to study these networks, leading to the discovery of 14 promising protein-protein interaction targets.
A new, battery-free sensor can detect water leaks in buildings, enabling greater protection and reducing costs. The sensor, powered by nanotechnology, sends alerts to smartphones when exposed to moisture, making it more accessible for building owners.
Patients with lupus who take their medications consistently have a 39% lower risk of developing type 2 diabetes. The study found that antimalarial drugs like hydroxychloroquine significantly protect patients against the complication if taken as prescribed for at least 90% of the time.
African satyrid butterfly Bicyclus anynana adjusts its wing eyespot size in response to low temperatures, changing the pattern to resemble a dead leaf. This complex physiological and molecular response is unique among butterfly species, suggesting it evolved gradually over millions of years.
Professor Maddalena, director of UTA's Aerodynamics Research Center, has been elected a fellow of the Royal Aeronautical Society for his outstanding contributions to hypersonic research. He is a leading expert in mixing and combustion in turbulent supersonic flows and their application to hypersonic airbreathing propulsion.
A new study by University of Bristol scientists found that secular cultures with tolerance of minority groups tend to have more wealth, education, and democracy. The research suggests that changes in culture generally come before economic improvements, making cultural values a crucial predictor of future prosperity.
A study published by Ohio State University found that people enjoy seeing bad guys get punished more than being forgiven, but appreciate forgiveness stories as the most meaningful. The researchers discovered that readers take less time to respond to narratives with equitable retribution than those with under- or over-retribution.
A recent study found that personal values in post-Soviet countries are primarily determined by national pride, rather than education, age, religiosity, or social status. Despite high rates of divorce and abortion, respondents expressed conservative views on individual choice practices, highlighting a cultural shift towards patriotism.
The selected scientists and engineers will participate in a week of intensive public engagement and science communication training, networking, and plan development. The fellows will return to their institutions with resources and connections to develop, implement, and evaluate their public engagement activities.
Researchers at Penn Medicine discovered that changes in DNA sequence can trigger chromatin misfolding in white blood cells, increasing the risk of developing Type 1 diabetes. The study found that these misfolded regions occur before the disease onset and may serve as a diagnostic tool.
Researchers at University of Arizona develop mathematical model to simulate PFAS migration through soil and groundwater. The majority of PFAS accumulate in the soil, where they migrate down slowly, posing a significant risk to human health.
Researchers at EPFL have developed a novel formulation that describes how heat spreads within crystalline materials. This breakthrough will help engineers design next-generation electronic devices by explaining hydrodynamic phenomena, which are prevalent in materials like graphite and graphene.
A new study found that one in five operations could lead to unexpected bills from out-of-network providers, including surgical assistants who were not part of the patient's insurance plan. The average potential surprise bill was $2,011, with some states experiencing much higher rates of surprise billing.
Researchers at Sanford Burnham Prebys Medical Discovery Institute found that prebiotics mucin and inulin slowed melanoma growth in mice by enhancing anti-tumor immunity. The study suggests a potential benefit of prebiotics in treating cancer or augmenting current therapies.
Researchers at Emory University have developed a new approach to organic synthesis that can efficiently transform simple molecules into complex ones with 3D structures. This method opens up whole new chemical space for potential drug targets, enabling the creation of more direct and efficient pathways for pharmaceutical research.
A study using large health insurer claims data found that approximately 1 in 5 patients received surprise out-of-network bills after having in-network elective surgery. The average potential balance was $2,011, with anesthesiologists and surgical assistants being the most common providers involved.
Researchers at Case Western Reserve University have developed a new method to preserve donated kidneys using a drug that generates S-nitrosothiols, restoring flow-through and reducing resistance. This could extend the number and quality of kidneys available for transplant, saving more people with end-stage renal disease.
Research led by the University of Arizona found that the US East and Gulf Coasts have different responses to storm surges due to ocean and atmospheric circulation interactions. The Gulf Coast, particularly New Orleans, is highly sensitive to tropical cyclone characteristics, leading to elevated storm surge heights.
Researchers at Northwestern University have developed a new method to visualize the dynamic motion of atoms in atomically thin 2D materials. The technique reveals that sulfur atoms in MoS2 move continuously to vacant areas, causing grain boundaries to separate and leading to material failure.
New research found that the accumulation of tau and amyloid proteins in the brain significantly alters gene expression, particularly in genes related to inflammation. The study provides new insights into the progression of Alzheimer's disease and highlights potential pathways for treatment.
A pilot program launched by the Berlin Institute of Health aims to enhance the quality and value of translational research through training, tools, and monetary incentives. The QUEST Center's initiative seeks to address concerns over transparency and reproducibility in biomedical science.
Researchers created a digital amplifier model using a deep neural network that can accurately simulate the sound of various guitar amplifiers, including popular brands like Marshall and Orange. The study uses black-box modelling to replicate the observed input-output mapping of analogue circuitry.
A team of scientists has created a new class of 3D-printed biomaterials that can direct the regeneration of functional tissue in damaged cartilage. The materials are designed to provide cells with the exact cues they need to form tissue organized in the same way as natural cartilage.
Researchers conducted a large trial of MRSA blood infections and found that combining two antibiotics was not more effective than using one alone, but led to more kidney injuries. The study's findings aim to guide best management for patients worldwide.
Researchers have developed a live-cell imaging technique that enables the visualization of fundamental processes in flower development and opens up new avenues for research on plant sexual reproduction. The technique, called light sheet fluorescence microscopy (LSFM), records movies of plant reproductive events for the first time.
Researchers at Cornell University found that traditional lab models hinder student engagement, while inquiry-based labs promote active learning and ownership over experiments. Exam scores remained the same, but inquiry-based labs improved student attitudes toward experimentation and scientific thinking.
A new international study led by UNSW Sydney reveals that the West Antarctic Ice Sheet melted rapidly during the Last Interglacial period, causing a multi-metre rise in global mean sea levels. The research suggests that the ice sheet is highly sensitive to future ocean warming, posing an urgent need to minimize warming.
Researchers at Texas A&M University developed a tool to identify the source of errors caused by software updates using deep learning. The algorithm, which analyzes performance counters, can find bugs in a matter of hours instead of days.
Researchers have visualized a broadly neutralizing human monoclonal antibody, RVC20, which blocks the entry of the rabies virus into cells. The findings highlight new perspectives for prevention and treatment of the deadly disease.
A new Yale study found rosiglitazone, a type 2 diabetes drug, is associated with a higher risk of heart problems, especially heart failure. The research analyzed over 48,000 patients and found a 33% increased risk of cardiovascular events compared to controls.
A recent study by Oak Ridge National Laboratory found that tree budburst, or the timing of leaf emergence, is becoming more variable in hotter regions due to rising temperatures. In contrast, cold climates show a more stable pattern of budburst year-over-year.
A recent study analyzing over 200 mumps virus genomes provides insights into the US outbreaks, revealing a dominant strain responsible for many cases. The research also demonstrates the value of high-quality genomic data in public health surveillance and suggests future efforts should incorporate whole genome sequencing.
Researchers have developed a new model to track object drift based on satellite data from GPS-equipped buoys in the Florida Current. The study finds that buoyancy has the greatest effect on an object's trajectory, with implications for cleaning up ocean litter and tracking algae movement.
Researchers discovered that both the yellow color and the black and yellow mosaic pattern are essential for luring prey during the day. The study also found that the yellow color alone was very effective at luring nocturnal insects.
A recent study found that taller young men may be less likely to develop dementia later in life. The research adjusted for factors such as education and intelligence, suggesting an association between height and reduced dementia risk.
The IADR Centennial Emerging Leaders Award recognizes young investigators who will lead groundbreaking research and discovery in dental, oral, and craniofacial research. The award winners are poised to advance health and well-being worldwide with their outstanding promise for service and leadership.
A type of micro RNA known as MIR1249 plays a key role in allowing bile duct cancers to resist chemotherapy. The researchers hope that targeting this molecule could make chemotherapy more effective.
Researchers found that primary care doctors rarely discuss safe driving and monitor patients for risky sexual behavior with adolescents who have a history of ADHD. The study highlights the need for additional resources and training to provide better care for these patients as they transition from childhood to young adulthood.
Researchers at the University of Cincinnati are using APOL1 genotyping to identify high-risk African American donors and reduce their chances of developing kidney disease. The study aims to optimize the health of organ donors by protecting them from genetic factors that increase their risk of kidney disease.
Scientists at Champalimaud Centre for the Unknown designed an experiment where mice had to infer water reward locations using indirect evidence. The study revealed key brain regions involved in inference and compared mouse performance to a human version of the task, highlighting the cognitive skill's importance.
A new study from the University of Surrey found that Cairo car drivers are exposed to dangerous levels of air pollution, particularly in cross-city routes. Drivers who leave their windows open can be exposed to 65% more PM10 and 48% more PM2.5 than those with windows closed and AC on.
A new study published in mSystems found that mice fed a high-protein, high-fat diet developed severe C. difficile infections, while those on a high-carbohydrate diet recovered. The researchers suggest that diet may promote protective microbial groups after antibiotics.
The round goby's exceptional adaptability is attributed to its immune system, which features up to 30 times more inflammatory genes than comparable species. This enables the fish to deal with pathogens and extreme environmental conditions, facilitating its successful colonization of diverse waters around the world.
A long-term study of 200,000 long-distance skiers found they were almost 30% less likely to develop Parkinson's disease. This 'motor reserve' dissipates with time and age.
Analyzing viral genomes from an outbreak can show how a virus is evolving and being transmitted. The study revealed new links between cases that first appeared unrelated and details about how the disease was spreading in Massachusetts and elsewhere in the US.