A new meta-analysis found that clozapine is associated with decreased insomnia and a lower risk of suicide in patients with schizophrenia. The study suggests that clozapine's ability to improve sleep quality may be linked to its reduced suicide risk, and highlights the importance of assessing and treating insomnia in these patients.
Researchers have identified a possible way to help break the cycle between sleep disturbances and Alzheimer's disease. A small study found that people who took a sleeping aid experienced a drop in key Alzheimer's proteins.
A machine learning model has been developed to predict a patient's risk for a sleep disorder using demographic, lifestyle, physical exam results, and laboratory values. The model identified depression, weight, age, and waist circumference as the greatest predictors of a sleep disorder diagnosis.
SourcePLOS·JournalPLOS ONE·TypeComputational simulation/modeling·DateApr 12, 2023
A large UK Biobank study found that poor sleep quality may bolster genetic susceptibility to asthma, potentially doubling the risk. A healthy sleep pattern was associated with a lower risk of asthma, and spotting and treating sleep disorders early on might lessen the risks.
Researchers found that women with multiple sclerosis were more likely to report sleep disorders, including obstructive sleep apnea, insomnia, and sleepiness. Insomnia mediated more than 10% of the cognitive problems reported by women with MS, while sleep apnea accounted for 34%.
A study modeled the factors influencing sleep in menopausal women, revealing that hot flashes are a key predictor of insomnia. The researchers also found that some symptoms don't necessarily go away over time and can have long-term effects on health.
A new meta-analysis found that sleeping fewer than six hours per night after COVID-19 vaccination was associated with a weakened antibody response. The study highlights the need for simple behavioral interventions like sufficient sleep to improve vaccine efficacy during the pandemic.
A new study found that poor sleep is associated with compromised cardiovascular health in middle and old age, with men losing nearly 7 years of heart disease-free life compared to healthy sleepers. Women also experienced a significant loss of normal heart health, with up to 2 years lost due to general poor sleep.
A new study found significant links between sleep disturbances and the risk for developing dementia over a 10-year period. Sleep-maintenance insomnia was associated with a lower risk of dementia, while sleep-initiation insomnia and sleep medication use were linked to an increased risk.
SourceElsevier·JournalAmerican Journal of Preventive Medicine·TypeData/statistical analysis·DateMar 6, 2023
Research finds people with insomnia are 69% more likely to have a heart attack compared to those without the sleep disorder. Insomnia is also associated with an increased risk of heart attacks in people with diabetes and those who get less than five hours of sleep per night.
A recent study conducted in Japan found that moderate and intense physical activity favors good sleep in middle-aged Japanese women. The research used an isotemporal substitution approach and replaced sedentary behavior with moderate-to-vigorous physical activity, resulting in improved sleep quality. Interestingly, this association was...
A new study found that sleep medications increase the risk of dementia in white adults. However, the relationship between sleep medications and dementia risk varies by medication type and socio-economic status. The study suggests that patients with poor sleep should consider alternative solutions before taking medications.
Researchers found that spinal cord stimulation improved insomnia severity index and Epworth sleepiness scale scores by at least 30% in 39.1% and 28.1% of participants, respectively. The study also established minimally clinical important difference values to gauge treatment success.
A study by researchers in Brazil found that loss of muscle mass during COVID-19 hospitalization is associated with the development of persistent symptoms such as weakness, shortness of breath, and fatigue. The study also showed that patients who lost more muscle mass had higher healthcare costs six months after discharge.
A new study using closed-loop, acoustic stimulation neurotechnology shows significant improvements in sleep quality and autonomic nervous system function in adults with insomnia. The intervention, called CR-SOP, was found to reduce insomnia symptoms and improve heart rate variability and baroreflex sensitivity.
A new study analyzing over 14,000 people found that parents with sleep disorders have a significantly higher risk of experiencing stress. The study also discovered that children with sleep disorders can nearly double the risk of their parents developing insomnia and sleep apnea.
The American College of Physicians recommends using cognitive behavioral therapy (CBT) or second-generation antidepressants as initial treatment for adults with moderate to severe major depressive disorder. The guideline also suggests considering combination therapy and discussing patient preferences when selecting a treatment.
Research published in Occupational & Environmental Medicine found that frequent visits to urban green spaces were associated with lower use of prescription meds for depression, anxiety, insomnia, high blood pressure, and asthma. The frequency of green space visits was linked to a significant reduction in medication use, particularly am...
Researchers have identified a new genetic pathway involved in regulating sleep from fruit flies to humans. The Pig-Q gene is associated with sleep regulation in both humans and animals, providing a novel insight into the genetics of insomnia.
A study followed over 7,000 Canadians for three years to find that being female, physically active, and not obese were key to maintaining excellent health. Factors such as high income and social support also played a crucial role in optimal aging.
A randomized controlled trial found that a low-carbohydrate, high-fat diet helped patients with type 2 diabetes achieve better weight loss and glucose control over a 6-month intervention compared to a high-carb, low-fat diet. However, changes were not sustained 3 months after the intervention.
A recent study published in Mayo Clinic Proceedings found that people who are physically fit have a lower risk of needing prescription sleeping pills. The research, based on data from Norway's HUNT study, suggests that being in good physical shape can help improve sleep quality.
A new study from the University of East Anglia found that overweight women are more likely to experience symptoms of long Covid. The research also shows that people with long Covid are much more likely to need additional and lasting NHS care than those who make a swift recovery.
A new study by Rutgers researchers found that young people treated for sleep disorders with benzodiazepines like Xanax may be at a higher risk of overdose. The study examined over 90,000 newly prescribed benzodiazepine patients and found an increased risk of overdose compared to other prescription sleep medications.
A Michigan Medicine-led study reveals that transgender youth are 5.4 times more likely to experience insomnia and three times more likely to suffer from sleep apnea compared to cisgender youth. Gender-affirming therapies may offer a protective effect against worsening sleep health, according to the researchers.
A large UK Biobank study found that poor quality sleep, including insomnia, short/long sleep duration, snoring, and daytime sleepiness, is associated with a heightened risk of developing glaucoma. The study suggests that targeted screening of high-risk groups and sleep intervention may help prevent the disease.
Studies on prion diseases in mice reveal coordinated gene expression changes before symptoms appear, shedding light on selective vulnerability and potential treatment targets. Researchers predict disease progression using new methods, suggesting therapies may be more effective when applied early.
Researchers studying fruit flies found that brain neurons adapt to help the flies stay awake despite tiredness in dangerous situations, and fall asleep after an intense day. Time-restricted feeding also improved sleep quality in the flies, suggesting a potential therapeutic approach for humans.
A new study from Uppsala University found that using a weighted blanket at bedtime increases melatonin production by about 30 percent. The researchers also discovered that the weight of the blanket (12% of participant's body weight) reduced stress system activity, but had no effect on oxytocin and cortisol levels.
A new study found that medical cannabis users reported significant improvements in pain management, social functioning, and overall health. The majority of participants were able to stop or reduce their opioid use, with some experiencing a five-fold decrease in hydrocodone prescriptions.
Researchers from the European Insomnia Network found that outdoor nighttime temperatures outside thermal comfort can affect human sleep. To combat this, try keeping a bedroom below 25 degrees Celsius, using fans instead of air conditioning, and staying hydrated during heatwaves.
A new Canadian study has found that older people with insomnia are at greater risk of developing memory decline and long-term cognitive impairment such as dementia. Insomnia was specifically related to worse memory performance compared to those with some insomnia symptoms alone or no sleep problems.
A meta-analysis of 64 longitudinal studies found that mental health problems remained elevated globally during the pandemic, with North Americans suffering from increased anxiety and depression. In contrast, Latin America and Europe experienced higher rates of insomnia.
Research found that sleep deprivation dampens activity in social cognition brain network and is associated with reduced altruism. A 10% drop in donation amounts was observed after losing an hour of sleep due to Daylight Saving Time.
A new Flinders University analysis found that people reporting symptoms of both insomnia and obstructive sleep apnea are at an increased risk of death compared to those without the conditions. The study highlights the importance of self-reported symptoms and risk factors, and could lead to greater and more rapid assessment in populatio...
The study found a 31% decline in sleep medication use between 2013 and 2018, with the strongest decrease in FDA-approved medications. Behavioral treatments for insomnia are increasingly encouraged due to their effectiveness and reduced risk of adverse outcomes.
A new study from the University of Missouri-Columbia found that American military veterans are less willing to seek treatment for sleep and alcohol use problems compared to physical health issues. Discrimination experiences also play a significant role in reducing treatment-seeking among veterans of color.
A Rutgers study found that participants with severe insomnia and high rates of alcohol use had lower blackout frequencies than those with low insulinemia, suggesting a potential link between circadian misalignment and altered alcohol metabolism.
A U-shaped pattern of sleep duration across life stages was found, with age 40 being the lowest point and efficiency stabilizing from ages 30 to 60. Study participants wore accelerometers for seven consecutive days, providing an objective measure of sleep time.
A new study presents a self-powering smart pillow that tracks head movement during sleep using triboelectric nanogenerators. This system could improve the accuracy of sleep monitoring and have uses beyond tracking sleep, such as monitoring patients with cervical spondylosis or detecting early warning signs for falls.
Physicians recognize benzodiazepine dependence as a significant contributor to the opioid crisis, coined a new term CPBD. Long-term treatment can lead to severe withdrawal symptoms and recurrence of underlying anxiety and insomnia.
A new study reveals that long-term insomnia symptoms can lead to poorer cognitive functioning in retirement age. The Helsinki Health Study found a clear connection between severe insomnia and worse cognitive function among those on statutory pension.
A new study from Tel Aviv University finds that women aged 55 and over who snore are at significant risk for sleep apnea, which can be fatal. The researchers warn that the phenomenon often occurs during sleep, causing women to be unaware of their condition.
Researchers have discovered a new sleep molecule, microRNA-137 (miR-137), that regulates hypocretin levels for normal sleep. The study found that miR-137 is associated with hypocretin regulation and sleep disorders such as narcolepsy and insomnia.
A randomized trial found that an internet-delivered CBT-I program tailored for Black women resulted in significant improvements in insomnia symptoms and sustained gains at 6 months. Compared to a standard program, the culturally-tailored version improved engagement with treatment and led to better sleep outcomes.
A mobile system developed by ETH Zurich researchers aims to promote deep sleep through auditory brain stimulation, showing promise in enhancing slow waves during deep sleep in older adults. The system involves a headband that continuously measures brain activity and triggers short auditory signals to synchronize neuronal cells.
Researchers developed an algorithm to classify 16 distinct adult sleep patterns based on arm acceleration data from 100,000 UK Biobank participants. These patterns can be used to diagnose insomnia and develop personalized treatment methods, offering new insights into human sleep behavior.
Researchers at Massachusetts General Hospital found that medical marijuana users were more likely to develop cannabis use disorder (CUD) than expected, particularly those seeking relief from anxiety and depression. The study suggests that the current system of dispensing and using medical marijuana may be contributing to this issue.
A randomized clinical trial found that acquiring a medical marijuana card led to a higher incidence of cannabis use disorder but no significant improvement in symptoms of pain, anxiety, or depression. Immediate access to medical marijuana resulted in improved sleep.
Researchers found that stress, anxiety, and worries about health consequences contribute to sleep issues among essential occupation workers. The study suggests that implementing measures promoting health and well-being can prevent future illness and sick leave.
A study published in The Nurse Practitioner found that maladaptive coping strategies such as using caffeine and taking daytime naps can actually decrease sleep quality. Patients who used these strategies had longer times to REM sleep and more frequent nighttime arousals compared to those who did not use them.
Researchers found that 1% of US adults taking opioids are also prescribed benzodiazepines and other sedatives. This polypharmacy approach is linked to increased side effects and may pose dangers to vulnerable populations.
A long-term study of children's insomnia symptoms reveals that many persist into young adulthood and are more likely to develop an insomnia disorder. The research suggests that early intervention is crucial, and behavioral therapies may be effective in addressing chronic sleep issues.
A randomized, double-blind study found suvorexant to be effective in reducing insomnia severity and night sweats in peri- and postmenopausal women. The medication showed promise as a treatment for chronic insomnia in midlife women.
Researchers found a significant increase in overdose deaths involving gabapentinoids and z-drugs between 2000 and 2018. The proportion of deaths increased by more than three-fold, coinciding with exponential prescription increases. Co-usage with opioids was common, with over 67% of overdose victims having both substances in their system.
A recent study by Oregon State University found that night shift nurses are more likely to suffer from poor sleep, PTSD, depression, anxiety, and inflammation. The researchers also discovered a significant disparity in sleep quality among Black nurses, highlighting the impact of systemic racism on their health.
A recent study found that more than half of nurses experienced difficulty sleeping during the first six months of the COVID-19 pandemic, with reduced sleep increasing odds of anxiety and depression. The researchers urge employers to address work stress and provide support for mental healthcare.
A digital version of cognitive behavioral therapy (dCBT) has been shown to reduce insomnia, depression, and anxiety during pregnancy. The treatment also reduced symptoms of insomnia and depression in non-depressed women for up to six months postpartum.
A study published in the European Respiratory Journal found that people with both insomnia and obstructive sleep apnoea are at a higher risk of heart problems and mortality. Participants with co-morbid insomnia and sleep apnoea were two times more likely to have high blood pressure and 70% more likely to have cardiovascular disease.
A study of US adults found a link between cannabis use and extremes of nightly sleep duration, with recent users more likely to report short or long sleep. Heavy users were 64% more likely to experience short sleep and 76% more likely to experience long sleep compared to non-users.