Articles tagged with Metabolic Syndrome
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Researchers followed nearly 6,000 women with metabolic syndrome over nine years, finding that cardiorespiratory fitness reduced overall deaths and heart disease-specific deaths to rates similar to those without the condition. Higher levels of cardiorespiratory fitness were associated with lower risk factors and improved heart health.
The metabolic syndrome is frequently present in middle-aged subjects, coinciding with adverse cardiovascular changes, including inflammation, thickening of the heart, and atherosclerosis. Every additional component of MS increases the likelihood of cardiovascular damage.
The study found a strong social gradient in metabolic syndrome, with individuals from lower socio-economic positions having a higher risk of the condition. Despite healthier lifestyles among those with higher education levels, the risk was still significantly lower for those with higher education.
A new European consensus definition of the metabolic syndrome (MetS) reveals a high prevalence, with 38% of men and 36% of women affected. The MetS is associated with increased cardiovascular mortality rates, particularly in diabetic women, highlighting gender-specific risk factors.
Retinoid X receptor heterodimers are potential therapeutic targets for metabolic syndrome, according to a review article by UT Southwestern's Dr. David Mangelsdorf and Dr. Andrew Shulman. Activating specific RXR complexes may help regulate lipid metabolism and reduce the risk of heart disease and other related illnesses.
A VCU study found that low-dose oral contraceptives double the risk of cardiovascular events, such as heart attacks and strokes, among women. Women with PCOS or metabolic disorders are particularly at increased risk.
Researchers at Cedars-Sinai Medical Center found that patients with metabolic syndrome and moderate coronary calcium have a greater chance of having blockage in their arteries. The study analyzed 1,043 patients without known heart disease and found that those with metabolic syndrome had a significantly higher risk of ischemia during st...
A study examined the prevalence of metabolic syndrome in heart attack patients and found that 46% met the criteria. Patients with metabolic syndrome were older, more likely to be women, and had worse in-hospital outcomes, including increased risk of heart failure.
Researchers at Rutgers are studying the effects of plant extracts on metabolic syndrome, a condition characterized by obesity, hypertension, and high insulin levels. The center aims to identify chemical compounds with therapeutic potential and develop new treatments for this growing public health concern.
Researchers discovered significant differences in lipoprotein sizes and subclasses among severely obese white and black children, indicating higher cardiovascular risk for the former group. This study emphasizes the importance of addressing obesity-related health disparities in childhood.
A recent study by Fred W. Turek and Joseph Bass found a possible link between sleep disturbances and metabolic syndrome in mutant mice. The research suggests that altered circadian rhythms and hormone regulation, including leptin and ghrelin, may play a role in the development of obesity, diabetes, and cardiovascular disease.
A new study on anthrax attacks suggests post-attack vaccination plus antibiotic therapy is the most effective strategy. Meanwhile, an analysis of data from a large randomized trial found that both metformin and lifestyle changes can slow metabolic syndrome progression, with lifestyle change providing greater benefits.
A recent study found a high prevalence of metabolic syndrome and overweight among Chinese adults, with increased risk factors in northern China and urban residents compared to rural areas. The findings suggest that economic development and lifestyle changes may contribute to the growing obesity crisis in China.
Research suggests that excessive visceral and muscle adipose tissue accumulation is associated with a higher prevalence of metabolic syndrome in older adults, regardless of their body weight. Visceral fat was linked to an increased risk, while subcutaneous thigh fat showed an inverse association in obese individuals.
A recent study found that nearly a third of college students are overweight, while six percent are pre-diabetic. The findings suggest that early screening is crucial for preventing long-term health problems. Researchers also discovered that polyunsaturated fat intake may be linked to slower growth of prostate cancer.
Study reveals nearly two times higher likelihood of metabolic syndrome in women with PCOS, leading to increased risk of early-onset cardiovascular disease. Women with both conditions exhibit more severe insulin resistance.
Researchers found that inhibiting SCD1 decreased body fat and prevented obesity and metabolic syndrome in mice. Blocking SCD1 also increased expression of genes involved in energy expenditure, providing insights into its role in metabolism.
A new study found that pre-diabetes prevention efforts are worth every penny, with a one-on-one weight loss and exercise program showing a 58% reduction in Type 2 diabetes risk. Lifestyle interventions could delay the onset of diabetes by an average of 11 years and reduce the risk of developing diabetes by 20%.
Researchers discovered that mice lacking two related fatty acid binding proteins exhibit striking changes in their lipid profiles and strong resistance to diet-induced obesity and other conditions. The proteins appear to play a crucial role in integrating metabolic and inflammatory responses underlying metabolic syndrome.
Research found that total sleep time decreased as body mass index increased, except in severely obese individuals. Sleeping less than 16 minutes per day was associated with a lower BMI.
A new study suggests that insufficient sleep may be a contributing factor to weight gain and the development of metabolic syndrome. This condition increases the risk of serious diseases such as diabetes and cardiovascular disease.
A review of nine studies found that pre-diabetics using weight-loss interventions can lose between 2-3 kilograms or four to six pounds in one to two years. The interventions also decreased blood sugar levels, blood pressure, and cholesterol levels slightly among pre-diabetics.
The study found substantial improvements in exercise groups, including a 16% increase in aerobic fitness and a 17% increase in strength fitness. In contrast, the control group showed less improvement, indicating that exercise is an effective treatment for metabolic syndrome in older adults.
Researchers found that apocynin reduced ROS production in fat cells, restored adipocytokine production, and improved diabetes. Accumulated fatty tissue is a major source of ROS in obesity, acting as an early trigger of metabolic syndrome.
Heavy lifetime alcohol users have a 60 percent greater risk of developing metabolic syndrome compared to those in the lowest category. The study found that drinking patterns independently predict the risk of metabolic syndrome.
A study published in JAMA found that metabolic syndrome is associated with poor cognitive outcomes in elderly individuals. Participants with the metabolic syndrome and high inflammation showed a significant increase in cognitive impairment and four-year decline in cognitive testing scores compared to those without the metabolic syndrome.
Researchers found a strong correlation between PCOS and initial evidence of calcium deposits signaling blood vessel disease. Women with both PCOS and metabolic cardiovascular syndrome were at an even greater risk of calcification in coronary arteries.
A five-year study of over 2,600 elders found a significant link between the metabolic syndrome and cognitive decline. Elders with both the syndrome and high levels of inflammation showed a higher risk of cognitive decline, highlighting the importance of addressing cardiovascular risk factors to prevent dementia.
A recent study found that maintaining a stable weight, even for obese individuals, significantly reduces the risk of heart disease. The study, which followed over 2,500 young adults for 15 years, revealed that those who gained weight were nearly five times more likely to develop metabolic syndrome and related health issues.
A study found that surgical weight loss programs significantly improved metabolic syndrome symptoms, with a 95.6% resolution rate for patients with the condition. Laparoscopic gastric bypass surgery resulted in greater weight loss and better blood lipid profiles compared to vertical banded gastroplasty.
Researchers found that lean mass, intra-abdominal fat, and inflammation biomarker sTNFR1 are higher in women with metabolic syndrome, independently related to its severity. Analysis of these factors can help doctors identify postmenopausal women at increased risk for diabetes and heart disease.
A recent study examining obese postmenopausal women found that visceral fat storage was the main determinant of metabolic syndrome and increased cardiovascular disease risk. High-intensity exercise and general weight reduction were identified as potential strategies to reduce this risk.
A randomized trial found that a Mediterranean-style diet reduced the prevalence of metabolic syndrome by approximately one half after two years. The diet was rich in whole grains, fruits, vegetables, legumes, walnuts, and olive oil.
The study found that approximately 1 in 5 subjects had previously undiagnosed diabetes, while over 1 in 4 had impaired glucose tolerance. Lifestyle changes and medication may help prevent the progression of impaired glucose tolerance to full-blown diabetes and its associated complications.
Feldman et al report that donepezil treatment for six days is associated with a total societal cost saving of $224 per patient. The American Brain Coalition (ABC) was established to advocate for increased support for biomedical research.
A national health survey found that depression in young women is associated with an increased risk of developing the metabolic syndrome, a cluster of factors linked to heart disease. The study also suggests that depression can cause physiological changes that increase the risk of heart disease.
A recent study published in the New England Journal of Medicine found that nearly 50% of severely obese youth develop metabolic syndrome. The condition is associated with worsening body mass index and insulin resistance, increasing risk for type 2 diabetes and cardiovascular disease.
Crestor effectively tackles elevated non-HDL cholesterol levels, a key risk factor for heart attacks and strokes, in patients with metabolic syndrome. The medication demonstrates significant results in reducing the incidence of these cardiovascular diseases.
A new study suggests that treating metabolic syndrome's risk-factor components might reduce stroke risk before Type 2 diabetes develops. Men with metabolic syndrome have a 78% greater stroke risk, while women have more than double the risk compared to those without the condition.
Recent studies show that overweight Hispanic youth are at an increased risk for developing type 2 diabetes and cardiovascular disease. Insulin resistance directly contributes to the development of metabolic syndrome, particularly in those with a family history of diabetes.
A study of Latino children found that nearly three in ten have impaired glucose tolerance, a precursor to type 2 diabetes, while obesity rates are twice those of non-Latino peers. Insulin resistance and metabolic syndrome increase the risk of chronic diseases.
A new study finds evidence of genetic linkages to metabolic syndrome in both black and white patients. The researchers also identified chromosomal regions linked to cardiovascular disease and type 2 diabetes risk factors. These findings bring us closer to discovering the actual genes responsible for metabolic syndrome.
A large study found a positive association between increasing levels of C-reactive protein and risk of developing hypertension. Women with higher levels of this inflammatory marker were about twice as likely to develop high blood pressure over a median follow-up period of 7.8 years.
Obese adults who lost 7% of their weight and did moderate-intensity physical exercise for six months improved their major blood vessel function by approximately 80 percent, regardless of type 2 diabetes status. This improvement in blood vessel function reduced the risk of developing arteriosclerosis and coronary heart disease.
A study found that more than half of children aged 8-17 had at least one metabolic syndrome risk factor, including low HDL levels and high triglycerides. The researchers detected the highest rates of multiple risk factors in children around puberty, ages 10-13.
A USC study finds that increasing insulin sensitivity can help prevent chronic diseases in Latino children. Overweight children with metabolic syndrome are less physically fit, but improving fitness could deter these diseases.
The XENDOS study shows that Xenical significantly improves weight loss, waist measurement, blood pressure, triglyceride levels, fasting plasma glucose, and HDL cholesterol in patients with Metabolic Syndrome. The treatment also reduces the risk of type 2 diabetes by 36%.
A study found that hostility in children is a risk factor for developing metabolic syndrome, a precursor to cardiovascular disease. High scores on hostility measures were associated with increased rates of obesity and insulin resistance in later years.
Teggreen, a green tea polyphenols product, improves lipid and glucose metabolisms in obese rats by enhancing insulin sensitivity and balancing fat deposit and burning. The study reveals significant benefits of Tegreen treatment, including decreased fasting blood glucose and serum triglycerides.
A study found that people with metabolic syndrome are 1.5 times more likely to develop a stroke than those without it, with women being 2.1 times more at risk. The condition is also associated with an increased risk of heart attacks and vascular-related deaths.
Researchers found that CRP levels above 3.0mg/L significantly increased the risk of heart attacks, strokes, and death from cardiovascular disease in women with metabolic syndrome. Higher CRP levels were also associated with higher cardiovascular risk, even among those with lower CRP levels.
A new study from the University of North Carolina at Chapel Hill found that Australian Aboriginals are more susceptible to diabetes due to excess weight. The researchers suggest lowering BMI guidelines to reduce the risk, which could potentially prevent up to 46% of diabetes cases.
In a large clinical trial, patients with impaired glucose tolerance who took acarbose were 25% less likely to develop type-2 diabetes than those taking placebo. Acarbose also helped reversion of impaired glucose tolerance to normal glucose tolerance. The main side effects were flatulence and diarrhea.
A study published in Psychosomatic Medicine found that chronic stress is associated with an increased risk of heart disease in men. The research, led by Peter P. Vitaliano, identified a general pattern connecting chronic stress to heart disease, including poor health habits and changes in body composition and metabolism.
Researchers found a link between polycystic ovary syndrome and increased coronary artery calcification, an early indicator of cardiovascular disease. Addressing insulin sensitivity and central obesity may reduce this risk in young women with PCOS.
A study of 254 women with Polycystic Ovary Syndrome (PCOS) found that 7.5% had undiagnosed diabetes, compared to 1% in the general population. Insulin resistance is a key factor in PCOS-related glucose intolerance and diabetes risk.