Articles tagged with Myocardial Infarction
A worldwide study of 7,500 patients found that giving steroids during bypass surgery does not improve health outcomes and may increase the risk of heart attack. The study challenges a decades-long practice in cardiac surgery, suggesting that steroids should not be used prophylactically.
The sodium pump's hybrid function enables simultaneous import of protons, raising questions about its role in pathologies. This discovery may have important implications for conditions like muscle exercise, heart attacks, and strokes.
Patients given aspirin after non-heart-related surgery had a higher risk of serious bleeding than those who did not receive aspirin. Aspirin did not reduce incidence of post-operative heart attacks and death, according to data from POISE-2.
A recent study published in JAMA found that metformin treatment did not improve ventricular function in patients with ST-segment elevation myocardial infarction (STEMI) without diabetes. The study showed no significant difference in left ventricular ejection fraction between the metformin and placebo groups.
A JAMA study finds that biodegradable polymer biolimus-eluting stents (BP-BES) have similar safety outcomes to durable polymer everolimus-eluting stents (DP-EES) after two years, with noninferiority found for death and heart attack rates. The rates of target-lesion revascularization were also noninferior between the groups.
Researchers developed a hydrogel that delivers enzyme inhibitors to damaged heart tissue, minimizing long-term damage and improving heart function. The gel's responsive design allows it to release inhibitors in response to the activity level of the enzyme.
Researchers identified plasma levels of microRNA 122 and 126 that decline before a person suffers a heart attack, suggesting these markers may help predict imminent risk. The discovery could lead to the development of a blood test to identify people at high risk of having a heart attack.
A blood test using high-sensitivity cardiac troponin T can accurately predict heart attack risk in patients with chest pain, allowing for targeted admissions and reduced hospital costs. The test's negative predictive value was found to be 99.8 percent for heart attack within 30 days.
The study found that aleglitazar did not decrease the time to cardiovascular death, nonfatal heart attack, or nonfatal stroke among patients with type 2 diabetes. The drug was associated with increased risks of kidney abnormalities, bone fractures, gastrointestinal bleeding, and hypoglycemia.
Researchers used cardiac magnetic resonance imaging to identify patients with mild heart disease who were at high risk of developing more serious heart problems. The study found that these patients had nearly three times the likelihood of experiencing a major cardiac event over time compared to those without a mild heart attack.
A comprehensive review of bariatric surgery data shows that death rates are reduced by 40% and heart attacks by half compared to non-surgical obese patients. Obesity is a significant health issue worldwide, associated with heart disease, type 2 diabetes, and shorter life expectancy.
A new study on Michigan's smoke-free indoor air law found a statistically significant reduction in cardiovascular disease and death with related hospitalizations decreasing by 2.03 percent after the ban implementation.
A new study reveals a significant disparity in heart attack mortality rates between regions of the US, with the South experiencing the highest death rates. The research suggests that socioeconomic and lifestyle factors, including lower median household income and unhealthy habits, may contribute to this disparity.
A new microfluidic method simulates blood flowing through narrowed coronary arteries to evaluate anti-clotting drugs like aspirin. The study found that while aspirin can prevent dangerous clots in some patients, it may not be effective for those with narrowed arteries.
Researchers have developed controllable chemical compounds that can deliver protective effects of toxic hydrogen sulfide gas, reducing heart attack injury by up to 70%. The technology aims to unlock the gas's therapeutic potential in treating conditions like Parkinson's and Alzheimer's disease.
A new study published in the Canadian Medical Association Journal found that younger adults experiencing heart attacks and angina received faster care if they were male. The study also identified gender-related factors affecting access to care, including anxiety levels and personality traits.
Scientists have identified a previously unrecognized gene variation associated with healthier blood lipid levels and reduced risk of heart attacks. The discovery uses a new approach to scan the genome for variations in genes that change protein function.
Researchers at UT Southwestern Medical Center have discovered a new pathway linking two major biological processes that occur after a heart attack, leading to potential cardioprotection. The study identifies the activation of the unfolded protein response (UPR) and the hexosamine biosynthetic pathway as key events in this process.
A study found that total joint replacement (TJR) reduces the risk of heart attack, stroke, or other 'cardiovascular events' in patients with moderate-to-severe arthritis. This may be due to increased mobility and physical activity levels, which have a positive impact on cardiovascular health.
Researchers at Monash University developed a new class of drug targeting alternative recognition sites on GPCRs to fine-tune protein behavior, reducing damage and potential side effects. The breakthrough could lead to the creation of a new treatment for heart attacks and heart failure.
A study published in the European Heart Journal reveals a nearly fivefold increased risk for heart attack in the two hours following an angry outburst. The researchers found that patients with cardiovascular events were more likely to have experienced anger immediately prior to the event.
A systematic review and meta-analysis found that outbursts of anger can trigger heart attacks, strokes, and other cardiovascular problems in the two hours immediately afterwards. The risk is particularly high for those with existing cardiovascular problems or a history of heart attack or stroke.
Researchers at the University of Eastern Finland developed a novel treatment using RNA molecules to target and enhance vascular endothelial growth factor gene (VEGF-A) production. This approach significantly reduced myocardial infarction size in mouse models, offering new hope for heart disease treatments.
A study analyzing over 2 million patients who underwent PCI found a significant association between blood transfusion and an increased risk of in-hospital heart attack, stroke, or death. The analysis also showed considerable variation in red blood cell transfusion practices among hospitals across the US.
A study by the American Academy of Neurology found that fatal heart attacks and strokes among firefighters frequently follow vigorous physical activity. The researchers analyzed data from 1998 to 2012 and discovered that 148 out of 199 events occurred after vigorous exercise lasting an average of 33 minutes.
The risk of heart attack or stroke increases significantly in the 30 days following a partner's death. Bereavement is associated with cardiovascular events and may be linked to adverse physiological responses during acute grief.
Researchers found that a cancer medication reduces sudden cardiac death risk in mice with abnormal heartbeats and heart failure. This promising treatment option could provide patients and clinicians with a new paradigm for treating life-threatening illness.
A new blood test measures a protein called cardiac myosin binding protein-C (cMyBP-C) to detect heart attacks more quickly. cMyBP-C is released to the bloodstream within just 15 minutes of cardiac damage, rising to significant levels in three hours.
Researchers found that patients treated with high-potency statins had a 28% lower risk of death compared to those on simvastatin. Ezetimibe addition showed no improved survival rate, contrary to previous hopes as a potential treatment for heart patients.
A GW researcher has discovered that gene therapy can elicit a regenerative response in pig hearts after a heart attack. The treatment utilizes the Cyclin A2 protein to stimulate cellular division and promote cardiac repair.
A study found that public defibrillators are underutilized in England, with only 1.74% of cardiac arrests being treated with the device. The authors suggest that more education and placement of defibrillators in public areas could improve survival rates.
A simple blood test can identify 85% of post-surgical heart attacks, which often go undetected due to a lack of symptoms. Heart attacks are the leading cause of death within 30 days of surgery, with 10% mortality rate.
Researchers found that hydrogen sulfide regulates the body's production of nitric oxide, which protects the heart muscle against cell death. The study's discovery has far-reaching implications for developing novel treatments for cardiovascular disease.
A new IUPUI study found that treating depression before cardiovascular disease onset can decrease the risk of future heart attacks and strokes. The study followed 235 older patients with depression, finding a 48% lower risk among those receiving collaborative care.
A large health care database study has found a twofold increase in the risk of heart attacks among men under 65 using testosterone therapy. The research also confirmed earlier findings that men over 65 experience a similar increased risk.
A new nanotherapy breakthrough designed to deliver statin medication directly to inflamed blood vessels could potentially prevent repeat heart attacks and strokes. The technology targets inflammation in blood vessels, reducing the risk of clots and cardiovascular events.
Researchers have developed a microparticle therapy that targets inflammatory cells causing damage after a heart attack, reducing lesion size by 50%. The therapy has potential to transform treatment of cardiovascular disease and could be translated for clinical use within two years.
A new study finds that heart attack survivors, particularly black and Hispanic women, are less likely to adhere to prescribed medications. The researchers highlight the need for targeted interventions to improve long-term adherence and optimal outcomes.
A study published in JAMA found that coronary artery calcium (CAC) density is associated with lower risk of cardiovascular events. Researchers suggest re-evaluating the CAC scoring system to incorporate density and other variables, as dense plaques may be more stable than previously thought.
A study published in the European Heart Journal found that physical fitness in teenagers can reduce the risk of heart attack later in life. Fit but overweight or obese men have a significantly higher risk of suffering a heart attack than unfit, lean men.
A new 'fluid biopsy' technique identifies circulating endothelial cells as markers in the bloodstream to predict early onset of heart attacks. The test distinguishes patients undergoing treatment for a recent heart attack from healthy controls, offering a potential solution for clinical use.
Researchers developed a test to predict early onset of heart attacks by identifying circulating endothelial cells (CECs) in the blood. The technique has been successful in distinguishing patients undergoing treatment for a recent heart attack with healthy controls.
Researchers found an association between a person's fitness as a teenager and their risk of heart attack in later life. The more aerobically fit men were in late adolescence, the less likely they were to have a heart attack 30 or 40 years later.
Research published in Neurology suggests that having shingles may increase the risk of having a stroke years later, especially in young adults. People aged 18-40 who had shingles were found to be at a higher risk of stroke, heart attack, or transient ischemic attack compared to those who did not have shingles.
A genetic trait linked to stress sensitivity is responsible for a 38% increased risk of heart attacks and deaths in patients with heart disease. Researchers identified a specific gene variation that causes an overactive stress response, leading to higher rates of cardiovascular disease and death.
A study published in the European Heart Journal found individuals with a family history of premature heart disease continue to have a higher risk of dying despite earlier referral to GPs, lifestyle changes, and drug treatments. Doctors are encouraging people to use Christmas gatherings to discuss their medical histories and reduce the ...
A recent study published in Clinical Journal of the American Society of Nephrology found that acute kidney injury is associated with higher mortality rates compared to heart attacks. Patients who experienced both conditions had a significantly higher risk of death.
Researchers found that women younger than 50 with a recent heart attack experience restricted blood flow to the heart in response to psychological stress. This may explain why younger women who are hospitalized after a heart attack face a greater risk of complications and dying compared to men of the same age.
Researchers identified critical role of stem cell factor in cardiac repair and regeneration, showing potential clinical benefits of gene transfer to reverse heart damage. The study demonstrated significant improvement in cardiac function and reduced heart muscle cell death.
A study found that younger Hispanic and black women have a higher risk of in-hospital death after a heart attack compared to white men. Additionally, they are more likely to suffer from diabetes and have limited access to treatment options such as percutaneous coronary interventions or coronary artery bypass surgery.
A new bioabsorbable magnesium stent has shown promising results in reducing the risk of heart attacks for up to three years after implantation. Of 46 patients, only two required vessel-opening procedures and one suffered a heart attack within the first year, with no incidents reported in the second year.
The study found that varespladib, an enzyme inhibitor, did not significantly reduce the risk of cardiovascular events in patients with recent acute coronary syndrome (ACS). Patients treated with varespladib had a higher risk of heart attack compared to those receiving placebo.
A study published in JAMA Internal Medicine found that beta-blocker medication given to patients with heart disease undergoing noncardiac surgery is associated with a lower risk of death and major adverse cardiovascular events. The effect was more pronounced in patients with heart failure or recent myocardial infarction.
A trial testing varespladib to reduce cardiovascular events showed the drug actually increased the risk of heart attacks and other events. Researchers found that patients treated with varespladib were more likely to experience sudden death, heart attacks, strokes, and unstable angina than those on placebo.
Researchers identify 18F-NaF as a promising tool to detect high-risk coronary plaques in patients with stable and unstable heart disease. The study suggests that this non-invasive technique could transform the way doctors identify, manage, and treat patients at risk of heart attacks.
Researchers discovered genetic differences between African Americans and European Americans that affect blood clot formation, providing a potential explanation for the racial disparity in heart disease outcomes. The study highlights the need for personalized treatment approaches based on an individual's genetic profile.
A study found that testosterone therapy was associated with a higher risk of adverse outcomes, including death, heart attack, or ischemic stroke, in men who underwent coronary angiography. The use of testosterone therapy was also linked to an increased risk of these events even among patients without underlying coronary artery disease.
Researchers at Temple University have discovered that inhibiting a specific protein called TNNI3K can limit damage from heart attacks and protect the heart from further injury. The findings have significant potential for translation into human patients and could lead to the development of a new treatment using a TNNI3K inhibitor.
A recent study published in JAMA Internal Medicine reveals that women and African Americans are at a higher risk of heart attack due to atrial fibrillation. The study found that patients with AF, especially women and African-Americans, have a more than double increased risk of heart attack compared to those without AF.
The TATORT-NSTEMI trial found that aspirating blood clots does not significantly reduce microvascular obstruction or the risk of death in patients with non-ST-elevation myocardial infarction (NSTEMI). Standard PCI without thrombectomy was shown to be equally effective.