Articles tagged with Myocardial Infarction
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Researchers compared ASCs and BMSCs from an elderly male donor to treat myocardial infarction in a rat model, finding that ASCs preserved more cardiac function. The study suggests age and health status of cell donors may impact the efficacy of stem cells in treating myocardial infarction.
A new compound developed by scientists at Scripps Research Institute protects heart cells from damage caused by heart attacks. The compound inhibits a specific enzyme, reducing tissue death by up to 34% and mitochondrial dysfunction.
A large Finnish study found that being married decreases the risk of fatal and non-fatal heart attacks in both men and women, across all ages. Married couples tend to have better health habits, social support, and earlier intervention, leading to improved treatment outcomes.
A national audit of percutaneous coronary interventional procedures found improved treatment times and increased use of primary PCI. The UK's PCI centers expanded services to treat more patients with acute coronary syndromes, reducing delays and improving patient outcomes.
A Kaiser Permanente study of 26,000 patients with diabetes found that controlling blood pressure and cholesterol is crucial in preventing heart disease. Patients who met guidelines for all three risk factors had a significantly lower rate of hospitalization for heart attack or stroke.
Survivors of heart attacks are three times more likely to develop depression due to their thought pattern about the event. Addressing threat perception through psychological interventions can help reduce this risk and promote a smoother recovery.
A study of 93,600 women aged 25-42 found that consuming three or more servings of blueberries and strawberries weekly reduced heart attack risk by 32% compared to those eating less than once a month. The flavonoids in these berries may help dilate arteries and prevent plaque buildup.
Research shows that individuals with depression after a stroke have a tripled risk of dying early and four times the risk of death from stroke. Screening for and treating depression in stroke survivors may be key to addressing these risks, according to study author Amytis Towfighi.
A new meta-analysis of 10 studies involving over 203,000 patients with anemia and heart attacks found that liberal blood transfusions increased the risk of death by 12% and had twice the odds of another heart attack. The study calls for rigorous randomized trials to determine when transfusions are appropriate.
A five-year study of almost 32,000 patients found that a heart-healthy diet significantly reduces the chance of a second heart attack and stroke in people with cardiovascular disease. The study showed that dietary modification offers consistent benefits beyond drug therapy alone, saving lives globally.
A new study published in the American Heart Association journal Circulation found that a healthy diet rich in vegetables, fruits, grains, and fish can reduce the risk of recurrent heart attacks and strokes by up to 35%.
Researchers at Imperial College London confirm the life-saving role of specialist heart attack centres through a new study. The findings show that primary angioplasty reduces death rates from heart attacks by 22% when bias is accounted for, highlighting the importance of making these centres widely available.
A study in Olmsted County, Minn., found a significant decline in myocardial infarction incidence after smoke-free workplace laws were implemented. The incidence of sudden cardiac death also decreased by 17 percent during the same period.
A large registry study found that patients with low levels of platelet inhibition after receiving a drug-eluting stent are at higher risk for blood clots and heart attacks. However, this responsiveness to clopidogrel was also linked to reduced bleeding complications.
A study published by the American Heart Association found that smoking survivors have a 30% higher risk of poor outcomes compared to non-smokers. Quitting smoking before a stroke also reduces this risk. The study suggests targeting smoking cessation programs for disadvantaged youth who are more likely to smoke.
The MASTER trial found that mesh-covered stents demonstrated improved restoration of blood flow compared to bare-metal or drug-eluting stents in heart attack patients undergoing angioplasty. The study showed a higher rate of ST-segment resolution with the new stent.
Researchers identified a distinct patient population that may benefit from prasugrel, a novel anti-platelet therapy, in those triaged to medical therapy following angiography. This subgroup showed lower rates of cardiovascular events and bleeding compared to clopidogrel.
Patients with prior open heart surgery who experience a severe heart attack and receive a coronary stent have similar outcomes to those without previous CABG. The study found that reperfusion rates were higher in the prior-CABG group compared to previous studies.
The European Society of Cardiology emphasizes the importance of timely medical care in cardiac emergencies. Early recognition and call for help can lead to better diagnosis and treatment outcomes. The organization aims to improve patient survival rates through education and collaboration among professionals.
A study of 334 patients with confirmed pulmonary embolism found that difficulty breathing, chest pain, and cough were present in 72%, 38%, and 19% of cases, respectively. Cancer was the most common risk factor, present in 27% of patients.
Patients with chest pain who call an ambulance receive timely treatment, including pre-hospital triage with telemedicine, which improves survival rates. For patients living far from hospitals with balloon treatment facilities, emergency medical personnel must be educated to perform and transmit ECGs to ensure proper referral.
University of Iowa researchers have discovered that CaM kinase II triggers cell death in heart cells following a heart attack. Blocking the enzyme can prevent heart cells from dying and protect against heart failure.
A recent study published in JAMA Network found that beta-blocker use was not associated with a lower risk of cardiovascular events among patients with coronary artery disease or at high risk for but without established CAD. However, the study did reveal that among patients with recent MI (one year or less), beta-blocker use was linked ...
A Scottish study found people with type 1 diabetes have a higher risk of heart attacks, strokes, and premature death compared to the general population. The researchers also discovered that women are more at risk than men, with higher rates of cardiovascular events and deaths from any cause.
Women experiencing early menopause are twice as likely to develop coronary heart disease and stroke. The study suggests that avoiding early menopause or delaying it through lifestyle changes may help reduce this risk.
A large European-wide study has confirmed that work stress is associated with a small but consistent increase in the risk of experiencing a first coronary heart disease event. The study found that individuals with highly demanding jobs and little freedom to make decisions are 23% more likely to experience a heart attack.
A large-scale synthesis of available randomized evidence found no association between omega-3 fatty acid supplementation and major cardiovascular outcomes. Despite widespread recommendation, supplementation with omega-3 PUFAs is not associated with lower risk of all-cause death, cardiac death, sudden death, heart attack, or stroke.
MicroRNA-145-based gene therapy reduces plaque size and increases stability in mice, providing new insights into atherosclerosis treatment. The approach also makes the fibrous cap area more resilient to rupture, a key event in heart attacks.
A new study by the University of Toronto found that men who experienced childhood sexual abuse are three times more likely to have a heart attack than men who were not sexually abused as children. The researchers also noted that the pathways linking childhood sexual abuse to physical health outcomes in later life may be gender-specific.
A study using cardiac magnetic resonance imaging in Iceland found that unrecognized heart attacks (UMI) were associated with an increased risk of death. The prevalence of UMI was higher than previously suspected, especially among individuals with diabetes.
Researchers found that successive leg compressions trigger natural protective mechanisms reducing damage after a stroke. The technique, called remote ischemic perconditioning, reduced stroke size by 25.7% in animal models, doubling its efficacy when combined with tPA, the current FDA-approved stroke therapy.
The study found that vorapaxar is beneficial for long-term secondary prevention of heart attacks in patients under 75 years old with no history of stroke and a body weight over 60kg. The drug's cardiovascular advantages are likely to outweigh the bleeding risks associated with it.
Researchers found that adding vorapaxar to standard antiplatelet therapy significantly reduces the long-term risk of recurrent cardiovascular events in patients with a prior heart attack. The study, published in the Lancet, showed a 20% reduction in cardiovascular death, heart attack, or stroke.
A new study found no significant difference between prasugrel and clopidogrel in preventing death, heart attack, or stroke in ACS patients who do not undergo coronary stenting or bypass surgery. However, prasugrel showed a lower risk of recurrent adverse events after 12 months of treatment.
Research from Bremen, Germany found that non-smokers experienced a 26% decrease in ST-elevation myocardial infarctions (STEMIs) following the introduction of a smoking ban. In contrast, active smokers showed little change in STEMI rates, highlighting the benefits of anti-smoking legislation.
A clinical trial launched by the NIH aims to determine whether a commonly used anti-inflammatory drug can reduce rates of heart attacks, strokes, and cardiovascular deaths in adults at high risk. The study will enroll 7,000 patients across the US and Canada over two years.
Researchers are testing whether lowering inflammation with methotrexate can reduce rates of recurrent heart attack, stroke, and cardiovascular death in high-risk patients. The 7,000-patient trial will follow participants for 3-5 years to determine the treatment's effectiveness.
A study published in JAMA found that patients treated with newer-generation drug-releasing stents had a significantly lower rate of major adverse cardiac events at 1 year compared to those receiving bare-metal stents. This was attributed to reduced target vessel-related reinfarction and ischemia-driven target-lesion revascularization.
A recent study published in JAMA found that endoscopic vein harvesting during coronary artery bypass surgery (CABG) has similar mortality rates and lower infection and wound complication rates compared to traditional open incision methods. The study, conducted on a large population of Medicare patients, refutes previous concerns about ...
A new protocol has excellent results and should become the standard of care for treating severe heart attacks. Paramedics trained to read ECGs expedite treatment by evaluating patients with chest pain and restoring blood flow to the heart within 30 minutes.
The trial found large reductions in blood pressure and LDL cholesterol, with estimated benefits of avoiding or delaying a heart attack or stroke by 28% among participants. The Polypill is a four-component tablet that contains three blood pressure-lowering medicines and a statin for lowering cholesterol.
A new study warns that online self-diagnosis can lead to overestimation of disease likelihood due to symptom-focused searches. This bias may result in consumers taking unnecessary medical actions, causing harm to themselves and society.
Researchers found SCAD occurs most frequently in men during extreme exertion and in women after childbirth, with a higher-than-expected rate of recurrence in females. Conservative therapies may be a better approach for some SCAD patients, while invasive procedures are associated with complications.
A Saint Louis University scientist is working to harness the anti-inflammatory activity of antithrombin to reduce the incidence and severity of heart disease. He has also been studying the control of blood clotting factors for 23 years, with a focus on improving the effectiveness of activated protein C.
A new UCLA study published in Basic Research in Cardiology found that heart attacks in late pregnancy result in worse heart function and more damaged heart tissue than in non-pregnant females. The research suggests that the heart may be particularly vulnerable to injury during this critical period, but partially recovers after giving b...
A study of 3,010 heart attack patients found that 40% were rehospitalized within 30 days due to the heart attack or other causes, with comorbid conditions like diabetes and COPD increasing risk. Additionally, half of heart patients make serious medication errors, even when pharmacists intervene.
A gene variant in sortilin, responsible for higher protein expression in liver, has been found to reduce cholesterol levels. The study reveals two mechanisms: increased LDL degradation and decreased APOB secretion via lysosomal targeting.
Researchers found that the immune response to a heart attack accelerates underlying atherosclerosis, leading to increased inflammation in atherosclerotic plaques. This study suggests a new therapeutic strategy for preventing heart attacks and strokes by targeting the immune system's role in exacerbating atherosclerosis.
A recent study published in PLOS ONE found a significant association between traffic noise exposure and an increased risk of heart attacks. The research showed that every 10 decibels of noise above the threshold resulted in a 12% higher risk of myocardial infarction.
A large-scale Canadian study has found that patients with chronic kidney disease are at comparable risk of future coronary events to those who have previously suffered a heart attack. This could lead to targeted treatment for high-risk individuals, including the use of statins to reduce 'bad' fats in the bloodstream.
A new study at Brigham and Women's Hospital found that living alone may be a risk factor for death, especially due to cardiovascular problems like heart attack and stroke. Participants with atherosclerosis who lived alone had a higher rate of death over four years compared to those who did not live alone.
Scientists at Joslin Diabetes Center have identified a new cause of cardiac damage after heart attacks in people with type 1 diabetes. A runaway autoimmune response triggered by alpha-myosin leads to chronic inflammation, cardiomyopathy, and heart failure. The study offers promising targets for future interventions to protect the heart.
A Tel Aviv University researcher found that cardiac patients living in high-pollution areas were 43% more likely to have a second heart attack, and 46% more likely to suffer a stroke. Long-term exposure to air pollution was linked to increased risk of mortality and recurrent vascular events.
A new index reveals that 71% of Australians live near specialist hospital care and four types of aftercare within an hour's drive. However, rural and remote communities face significant challenges in accessing cardiac care, with Indigenous people living at a lower rate than non-Indigenous Australians.
Research published in the journal Heart found that calcium supplements may increase the risk of heart attacks, while boosting dietary calcium intake has no significant heart health benefits. The study of nearly 24,000 participants suggests that high levels of calcium supplements may be harmful due to their impact on blood calcium levels.
A national survey found that systems treating severe heart attacks are expanding nationwide, with over 580 community-based STEMI systems registered in Mission: Lifeline. The survey also identified common barriers to implementing these systems, including competition among hospitals and finances.
A study found that behavioral support from peers and primary care office staff can help patients with poor blood pressure control improve their blood pressure levels by as much as starting a new drug. The intervention reduced systolic pressure by 7.2mmHg in the treatment group compared to 0.8mmHg in the control group.
A new study of 15 HDL-raising variants found no association with reduced heart attack risk, challenging the long-held assumption. The research uses genetic approaches to test biological hypotheses and highlights the value of human genetic information in understanding disease biology.
The Stent for Life Initiative is driving equal access to primary percutaneous coronary intervention (PPCI) in Europe, reducing mortality and morbidity among acute coronary syndrome patients. PPCI rates are increasing across participating countries, with a focus on improving patient awareness and streamlining healthcare systems.
Recent studies using mendelian randomization have failed to support a causal association between higher concentrations of high-density lipoprotein (HDL) cholesterol and lower risk of heart attack. Instead, findings suggest that raising HDL cholesterol may not uniformly reduce the risk of myocardial infarction in humans.