Articles tagged with Myocardial Infarction
Recent studies using mendelian randomization have failed to support a causal association between higher concentrations of high-density lipoprotein (HDL) cholesterol and lower risk of heart attack. Instead, findings suggest that raising HDL cholesterol may not uniformly reduce the risk of myocardial infarction in humans.
A new study of 15 HDL-raising variants found no association with reduced heart attack risk, challenging the long-held assumption. The research uses genetic approaches to test biological hypotheses and highlights the value of human genetic information in understanding disease biology.
The Stent for Life Initiative is driving equal access to primary percutaneous coronary intervention (PPCI) in Europe, reducing mortality and morbidity among acute coronary syndrome patients. PPCI rates are increasing across participating countries, with a focus on improving patient awareness and streamlining healthcare systems.
A lack of basic evidence is hindering the prevention of sudden heart attacks in sports, with a need to track all incidents like Fabrice Muamba's on-pitch collapse. Reliable data collection and cooperation among sporting organisations are essential to mitigate risks and improve understanding of the condition.
A study by the American Heart Association found that STEMI patients who went directly to PCI-capable hospitals received faster treatment, with an average time of 93 minutes from first medical contact to artery-opening treatment. This can improve a patient's chances of survival.
A new study by Beth Israel Deaconess Medical Center finds that heart attack survivors living near highways have a 27% higher risk of death within 10 years compared to those living far away. The risk recedes to 13% for those living between 200-1,000 meters from the roadway.
Researchers found that heart attack survivors living less than 100 meters from a major roadway have a 27% increased risk of dying over 10 years compared to those living at least 1,000 meters away. Long-term exposure to air pollution near roadways is also associated with an increased risk of cardiovascular death.
Researchers at the University of Delaware have found that the JAM-A protein helps prevent unwanted blood clots, which are a major contributor to heart disease and stroke. The study suggests that the protein may serve as a biomarker for predicting risk of these conditions.
Researchers discovered that strong light can activate a protein called Period 2, which regulates heart metabolism and minimizes damage from heart attacks. This finding suggests that daylight exposure could reduce the risk of having a heart attack or suffering damage from one.
Scientists have developed a new imaging method that combines PET and CT scanning to identify patients at high risk of a heart attack. The technique, which targets active calcification in coronary arteries, shows promise in improving heart attack prediction and reducing mortality rates.
Researchers found that EKG abnormalities in healthy elderly individuals increased the risk of heart attack. The study, which followed 2,192 adults aged 70 and older for eight years, suggests that EKGs could be used to detect heart disease earlier in patients without chest pain or symptoms.
A study of nearly 2000 US male health professionals found that moderate drinkers who survived a first heart attack had a lower risk of death from any cause and cardiovascular disease. The researchers discovered a 'U' shape effect, where heavy drinking increased mortality risk.
A study found that intravenous glucose-insulin-potassium (GIK) solution did not reduce the rate of progression to heart attack or improve 30-day survival in patients with chest pain. The treatment was associated with a lower risk of cardiac arrest or in-hospital death.
Paramedics can administer a mixture of glucose, insulin and potassium (GIK) to patients having a heart attack, reducing the rate of cardiac arrest and death by 50 percent. The treatment also reduces the severity of heart tissue damage from the heart attack.
Researchers at Thomas Jefferson University Hospital found carotid artery stenting to be safe and effective in patients over 70, with a low risk of adverse events. The study showed that while the risk increases with age, it remains extremely low even for those aged 85 and above.
New research from Brigham and Women's Hospital shows that ticagrelor significantly reduces the time to a second cardiovascular event or death, in addition to reducing total events. The study found that continued use of ticagrelor after a cardiac event is both safe and effective in preventing further cardiac events.
Coronary CT angiography (CCTA) scans identified nearly three times as many patients with coronary artery disease as standard methods. Low- to intermediate-risk patients who underwent CCTA were more than twice as likely to be discharged and had significantly shorter hospital stays.
A new study published in the New England Journal of Medicine reveals that highly detailed CT scans can safely and quickly rule out heart attacks among many patients with chest pain. The study found that patients with negative CT scans can be discharged from the hospital within hours, reducing costs and emergency room crowding.
A new study from Brigham and Women's Hospital suggests a strong link between telomere shortening and poor cardiovascular outcomes in patients with acute coronary syndrome. Telomeres are DNA-protein complexes that protect chromosomes from deteriorating, and their length is associated with increased risk of heart attack and death.
A new study has shown that delivering abciximab directly to the site of a heart attack can significantly reduce damage to the heart muscle. The treatment was found to be effective in reducing infarct size by up to 15% compared to no treatment or aspiration thrombectomy.
A study found a significant mismatch between the growth of cardiac catheterization laboratories and the need for percutaneous coronary intervention (PCI) procedures. PCI centers have grown 12.9% over eight years, but STEMI rates have declined, leaving many patients without access to care.
Researchers discovered that abciximab significantly decreased heart muscle damage in ST-segment-elevation myocardial infarction patients. Clot aspiration did not show similar benefits.
A recent study found that selected 90-year-old patients who experience acute heart attacks can benefit from coronary stenting, leading to reasonable outcomes and low cardiovascular readmissions. The study suggests that reperfusion therapy should be considered for this age group, which is expected to quadruple by 2050.
A study by Intermountain Medical Center Heart Institute has established a connection between microRNAs and impending heart attacks. Researchers identified six microRNA molecules linked to gene regulation, revealing lower levels in patients who experienced a heart attack within seven days.
Researchers found that among patients given an appointment for a follow-up exercise stress test, 70 percent actually underwent the test compared to 31 percent without pre-scheduled appointments. Patients with pre-scheduled appointments also waited significantly less time for the test.
A new class of platelet blockers has been shown to reduce the risk of recurrent cardiovascular events in patients with known atherosclerosis. Adding vorapaxar, an investigational platelet blocker, to standard antiplatelet therapy cuts the likelihood of another cardiac event by 13% compared to placebo.
Paramedics can reduce medical contact to balloon time by calling ahead to activate helicopter emergency medical services (HEMS), speeding up patient care. This study found that HEMS activation in the field or at a smaller hospital can save up to 48 minutes of treatment time
Researchers at Mayo Clinic are conducting a study to investigate the potential of a novel snake-venom peptide, cenderitide, to reduce cardiac and renal injury following a heart attack. The therapy may help prevent deterioration of cardiac and renal function in treated patients.
A study by UNC Health Care researchers found that a supercharged version of the protective protein focal adhesion kinase (FAK) can reduce heart attack damage by 50% in mice. The enhanced protein, called SuperFAK, was engineered to activate stronger survival signals and deactivate at the right time, reducing permanent heart damage.
Researchers have developed a modified protein, SuperFAK, that reduces cell damage after heart attacks by 50 percent without causing inflammation. The study suggests this protein may protect the heart during chemotherapy or following a heart attack.
A meta-analysis of eight clinical trials suggests that initial stent implantation for patients with stable coronary artery disease is not associated with improved outcomes compared to initial medical therapy. The study found no significant reduction in mortality, nonfatal heart attacks, or angina after a mean follow-up of 4.3 years.
Researchers found that naked mole-rats retain a tolerance for oxygen deprivation into adulthood, similar to infant humans. This discovery could lead to better brain cell protection during heart attacks or strokes.
A UCSF stem cell study conducted in mice suggests a novel strategy for treating damaged cardiac tissue after a heart attack. The approach potentially improves cardiac function, minimizes scar size, and avoids tissue rejection.
A systematic review and meta-analysis of previous studies found that short-term exposure to major air pollutants is associated with an increased risk of heart attack. The study suggests three possible mechanisms for this association: inflammation, abnormal cardiac autonomic system regulation, and increased blood viscosity.
A new study reveals that South Asians living with coronary disease in Alberta experience a lower quality of life compared to Canadians of European descent. The study, published in American Heart Journal, found that they have more frequent and severe chest pains, and are less physically active.
A Cedars-Sinai Heart Institute clinical trial has demonstrated that treating heart attack patients with their own heart-derived cells can help damaged hearts regrow healthy muscle. The study found a significant reduction in scar size and an increase in healthy heart muscle following the stem cell treatments.
A study published in The Lancet found that infusing patients' own cardiac stem cells into the heart after a heart attack reduces scar tissue by 50%. This breakthrough suggests that healthy heart muscle can be restored after previously thought-to-be irreparable damage.
A short spinning session can increase cardiac biomarkers, similar to a heart attack, but levels return to normal within 24 hours. Researchers hope to raise awareness among emergency treatment teams about the need for accurate assessment in patients with chest pains after exercise.
Patients with low levels of anti-PC in connection with acute coronary syndromes are at a greater risk of complications and premature death. Inhibiting inflammation and cell death may have a protective effect on cardiovascular disease.
A new study found that daily diet soft drink consumption may be associated with a higher risk of vascular events, including stroke and heart attack. In contrast, regular soft drink consumption and moderate intake of diet soft drinks do not appear to increase the risk of these events.
A lab study found that Gilenya, an MS treatment, reverses ventricular hypertrophy's symptoms and prevents fatal arrhythmias. Researchers discovered Pak1's role in heart disease and developed a potential new therapy.
A Northwestern University study reveals that individuals with low short-term risk may face very high lifetime risk of heart disease if they have just one or two risk factors, such as high cholesterol or blood pressure. The study found significant variations in risk by age, sex and race.
A Scripps-led study published in JAMA finds that the new drug cangrelor successfully 'bridges' patients with recent stents to cardiac surgery without excessive bleeding. The trial showed 99% of cangrelor-treated patients maintained target levels of platelet inhibition.
Research published in the FASEB Journal reveals that intestinal microbiota play a crucial role in determining the outcome of heart attacks in rats. The study found that probiotics can tilt the scales in favor of improved cardiovascular health, reducing heart attack risk and improving recovery from myocardial infarction.
A recent study published in Circulation: Cardiovascular Quality and Outcomes found that Asian-American heart attack patients received nearly the same quality of care as white counterparts, with improvements seen between 2003 and 2008. Despite this, disparities persist, including lower rates of aspirin use and smoking cessation counseling.
Research finds that grief increases heart attack risk by 21 times within the first day, declining steadily over the first month. Grieving spouses are also at higher long-term risk of dying from heart disease and strokes.
A recent study published in Circulation found that the risk of heart attack increases significantly after losing a loved one. The research, led by BIDMC, revealed an elevated risk of heart attack in the first 24 hours (21 times normal) and remained high for at least a month.
A study published in Archives of Internal Medicine found dabigatran to be associated with a higher risk of myocardial infarction and acute coronary syndrome. The research suggests that clinicians should consider the potential cardiovascular risks when using dabigatran, particularly in high-risk populations.
Researchers found that IL-1 limits advanced atherosclerosis features linked to severe complications in humans. Genetic inactivation of IL-1 signaling enhances plaque instability and reduces outward vessel remodeling in mice with advanced atherosclerosis.
A new highly sensitive troponin assay has been shown to be superior in diagnosing heart attacks, allowing for earlier and more accurate treatment. The study found that using this test on admission and measuring changes after 3 hours can rule out or confirm a diagnosis of heart attack with high accuracy.
A study found a 44% increase in hospitals offering definitive emergency care for heart attacks since 2001, but only a 1% increase in access to that care. Regional variation is significant, with highest access in the Northeast and lowest in the South.
A new study from Northwestern University finds that a significant increase in blood pressure during middle age increases the risk of heart attack or stroke. Maintaining low blood pressure early on can reduce this risk, with those who keep their blood pressure low having a significantly lower risk.
Mayo Clinic researchers found that elective angioplasties performed without on-site cardiac surgery capabilities pose no increased risk for patient death or emergency bypass surgery. The study included thousands of patients and showed mortality rates were similar for centers with and without on-site surgery.
Researchers analyzed over 150,000 adult ADHD users and found no significant association between current use of ADHD medications and an increased risk of heart attack, stroke, or sudden cardiac death. Cardiovascular disease rates were similar among new and ever-users of these medications.
Researchers have found that controlling the balance between two proteins can reduce the growth of dangerous cells in arteries. This finding could lead to a lower risk of further heart attacks and improved cardiovascular health.
Researchers found that reducing CXCR4 levels correlated with reduced infarct size and inflammation, but impaired recovery of blood flow and neovascularization. The study suggests that localized approaches, such as injecting stem cells with higher CXCR4 levels or CXCL12 variants, may be more effective in heart repair.
A study using coronary CT angiography found that women are at a significantly greater risk of cardiovascular events than men when experiencing large amounts of plaque build-up or extensive artery narrowing. In contrast, men with non-calcified plaque are at higher risk for major adverse cardiac events compared to women.
A recent study published in the Proceedings of the National Academy of Sciences found that inflammasome amplifies inflammatory responses in the heart, leading to further damage. Pharmacologic inhibition of inflammasome prevents heart enlargement and dysfunction.
Nationwide study reveals that fewer than 10% of heart attack patients transferred from initial hospital to one offering angioplasty are done within the recommended 30-minute timeframe. This delay increases the risk of death, particularly for STEMI patients who require immediate artery-opening procedure.
A study published in Circulation Research found that the size of a heart attack and subsequent left-ventricular function are significantly different based on the time of day onset of ischemia. The greatest amount of injury to the heart occurs when individuals have a heart attack between 1:00am and 5:00am.