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Science News for March 24, 2012


Complications in patients undergoing PCI tend to occur within first 30 days

A new study by Brigham and Women's Hospital found that cardiovascular disease and heart attack complications from PCI tend to occur within the first 30 days after treatment. The study analyzed patients who received anti-blood clotting drugs, with prasugrel showing a significant benefit in reducing these complications.

SourceBrigham and Women's Hospital·DateMar 24, 2012
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Fluke 87V Industrial Digital Multimeter

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Bone marrow stem cells improve heart function, study finds

A study led by Mayo Clinic researchers found that bone marrow-derived stem cells improved ejection fraction, a measure of the left ventricle's pumping ability, by 2.7% in patients with chronic heart failure. The most significant improvements were seen in younger patients and those with enriched CD34+ and CD133+ type of stem cells.

SourceMayo Clinic·DateMar 24, 2012

Study examines treatment of heart failure with bone marrow cells

A study published in JAMA found that using bone marrow cells to treat chronic ischemic heart failure did not show significant improvements in most measures of heart function. However, exploratory analysis revealed a significant effect on left ventricular ejection fraction (LVEF) among patients under 62 years old.

SourceJAMA Network·JournalJAMA·DateMar 24, 2012

New class of platelet blockers proves effective in phase III trial

A new class of platelet blockers has been shown to reduce the risk of recurrent cardiovascular events in patients with known atherosclerosis. Adding vorapaxar, an investigational platelet blocker, to standard antiplatelet therapy cuts the likelihood of another cardiac event by 13% compared to placebo.

SourceAmerican College of Cardiology·JournalJournal of the American College of Cardiology·DateMar 24, 2012
SAMSUNG T9 Portable SSD 2TB

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Telemedicine improves medication management, patient care

Internet-based telemedicine systems lead to more timely treatment decisions and medication adjustments for patients with high blood pressure. Patients who reported frequent blood pressure readings via a web-based portal received more appropriate pharmacotherapy and an overall reduction in cardiovascular risk.

SourceAmerican College of Cardiology·JournalJournal of the American College of Cardiology·DateMar 24, 2012

Stem cell therapy possibly helpful in heart failure patients

A new study found that using a patient's own bone marrow cells can help repair damaged areas of the heart caused by heart failure. The treatment increased left ventricular ejection fraction by a small but significant amount, and improved perfusion defects in patients with chronic ischemic heart disease.

SourceAmerican College of Cardiology·JournalJournal of the American College of Cardiology·DateMar 24, 2012

Long-term outcomes of TAVI show non-cardiac co-morbidities main cause of mortality

A Canadian study reveals that non-cardiac co-morbidities such as COPD and chronic kidney disease are the main predictors of late mortality after TAVI, emphasizing the importance of closer patient evaluation and follow-up. The study also shows that valve performance is maintained throughout the follow-up period.

SourceAmerican College of Cardiology·JournalJournal of the American College of Cardiology·DateMar 24, 2012

To get the full story you need to know the motifs

A team of researchers has developed a new tool to identify conserved motifs in the genomes of trypanosomatids, a group of parasites that include the causing agents of leishmaniasis and Chagas disease. The tool, named LeischCICS, uses bioinformatics tools to pinpoint potentially functional and regulatory sequences.

SourcePublicase International·JournalMolecular and Biochemical Parasitology·DateMar 24, 2012

Seeing is believeing with clogged arteries

A study found that patients who viewed images of their coronary artery calcium scores were more likely to take statins as directed and lose weight, with compliance increasing as disease severity increased. This suggests that visualizing the extent of cardiovascular disease can motivate patients to adhere to recommended therapies.

SourceAmerican College of Cardiology·JournalJournal of the American College of Cardiology·DateMar 24, 2012
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