Researchers found that OxyContin's abuse-deterrent formulation significantly reduced inhalation and injection, prompting users to switch to heroin. The study reveals a surge in heroin use across the US, with overdose risks increasing due to dealers cutting heroin with other substances.
A study by researchers at Brigham and Women's Hospital found that phobic anxiety is associated with shortened telomeres, a marker of biological aging. This association suggests that phobic anxiety may be a risk factor for accelerated aging, linked to increased risks of cancers, heart disease, dementia, and mortality.
A new study found that prenatal and early childhood exposure to the chemical solvent tetrachloroethylene (PCE) may be associated with poorer color-discrimination abilities. People exposed to higher levels of PCE from gestation through age 5 exhibited greater visual impairments, suggesting irreversible effects.
A widely-held belief that certain eye movements indicate lying has been debunked in a new study published in PLOS ONE. The researchers found no correlation between eye movement direction and truthfulness, challenging existing approaches to detecting deceit.
Researchers at the University of California, San Diego have identified two key regulatory proteins critical to clearing away misfolded proteins that accumulate and cause neurodegeneration in Huntington's disease. PGC-1alpha and TFEB provide a new therapeutic target for treating the disease, offering hope for its treatment.
A new approach using an HIV drug has significantly reduced the incidence of graft-versus-host disease (GvHD) in bone marrow transplant patients. The treatment redirects immune cells away from vital organs, reducing the risk of GvHD without compromising the patient's ability to fight cancer.
Scientists develop SMARTS, a customizable platform for autonomously regulating chemical reactions and temperature, mimicking biological systems. The material's dynamic feedback loops enable it to sense and modulate desired stimuli without external power, paving the way for intelligent medical implants and efficient buildings.
Research finds that both brain and muscle cells require the protein LRP4 to ensure robust communication. Without it, communication is inefficient and short-lived, contributing to disabling disorders like myasthenia gravis. The study suggests that delivering LRP4 through gene therapy may help bolster insufficient levels in patients.
Researchers found that silver nanoparticles are less toxic to bacteria than their released ions. The team's study suggests that controlling the rate of ion release can enhance antibacterial properties and mitigate environmental impacts. They also discovered hormesis, where low doses of silver ions stimulate bacterial growth.
Researchers found that the HIV protein vpu interferes with the immune response protein IRF3, dampening the ability of the immune system to protect against virus infection. This discovery could lead to the development of new antiviral therapeutics that target this interaction.
GigaScience offers a new era of publishing with its open access, open data format, hosting large datasets and analysis tools alongside traditional articles. This allows readers to test scientific conclusions using underlying data and analysis tools, overcoming reproducibility issues.
The American Health Assistance Foundation (AHAF) has awarded 22 new research grants to scientists studying innovative approaches to combat Alzheimer's disease, including repurposing existing drugs and examining the link between diabetes and cognitive decline.
The discovery of the new moon provides additional clues for unraveling how the Pluto system formed and evolved. The team is using Hubble's powerful vision to scour the Pluto system to uncover potential hazards to NASA's New Horizons spacecraft.
Physiologists and neuropathologists from the University of Zurich have identified the origin of metastasis formation in intestinal cancer cells. Cancer cells manipulate specific doorman receptors on blood vessel endothelium to enter other organs via bloodstream.
A new study found that gastric bypass surgery changes the gut microbiota composition in rats, increasing beneficial bacteria and altering peptide release. This shift resembles prebiotic treatment effects, suggesting a potential link between postsurgical gut modulations and improved metabolic outcomes.
Dr Mariana Fuentes' new book 'Dhyum the Dugong' takes readers on a journey through the life of a real dugong in the Torres Strait. The book aims to educate young Australians about the importance of protecting these endangered marine mammals.
Pre-notification by EMS significantly improved treatment times for stroke patients, including arrival-to-imaging and tPA treatment within 60 minutes. However, rates varied widely among hospitals and states, highlighting the need for improved stroke care systems.
The MU researcher's network model can analyze complex networks to identify the most damaging cyber attacks, protect critical infrastructure, and halt disease epidemics. By understanding network resilience, officials can prevent future problems and make informed decisions for conservation projects.
Researchers at UNC Health Care developed a non-invasive ultrasound method to detect cancer using blood vessel 'tortuosity.' This technique filters out tissue signals, allowing for clear visualization of small blood vessels. The study found a definitive difference between tumor and healthy vasculature, with limitations in detection depth.
Research funded by NIH shows that deaf people use auditory cortex for touch processing and visual stimuli more than hearing people. The finding suggests that the brain adapts and takes on additional sensory tasks in response to early loss of a sense, such as hearing.
A collection of articles investigates the impact of antiretroviral treatment on new HIV infections, exploring its potential epidemiological impact and affordability. The studies assess the utility of mathematical models and evaluate their consistency with real-world data.
Lauren Sciences LLC has received a grant from The Campbell Foundation to develop a V-Smart therapeutic for neuro-HIV. The treatment aims to deliver tenofovir across the blood brain barrier to treat viral reservoirs in the central nervous system.
The University of Minnesota has licensed its Clinical Decision Support technology to Omicron Health Systems, enabling improved coordination of patient care and research activities. The technology helps standardize medical records, facilitating communication and targeted treatments among clinicians and researchers.
LMU researchers have identified magnetosensory cells in trout that detect the Earth's magnetic field and convert it into nerve impulses. The cells sense the field through micrometer-sized inclusions of magnetic crystals, which are coupled to the cell membrane.
Astronomers discover that small dwarf galaxies in the Milky Way contain only a few stars and share the same birth date, indicating they were shut down by reionization. The relic galaxies provide evidence for a transitional phase in the early universe.
A landmark study reveals that police officers are at significantly higher risk for chronic disease, obesity, and suicide compared to the general population. The study found that shift work, stress, and lack of access to healthcare contribute to these risks.
Researchers at Michigan State University have developed a novel biofuel production process that produces energy more than 20 times higher than existing methods. The process, known as microbial electrolysis cells (MECs), uses bacteria to breakdown and ferment agricultural waste into ethanol.
Scientists from the University of Zurich identified a key role for the Sox10 gene in promoting melanoma development and proliferation. Suppressing this gene in mice inhibited cancer growth, offering new potential therapy avenues.
Researchers mapped ferroelectric structural distortions in individual nanocrystals using the world's most powerful transmission electron microscope. The study indicates that a monodomain ferroelectric state remains stable down to dimensions of less than 10 nanometers, and room-temperature polarization flipping was demonstrated down to ...
Scientists successfully grow nanorods of zinc oxide on a thin layer of polydiethylflourene, creating white LEDs that can be printed on paper or wallpaper for display purposes. This breakthrough method uses chemical methods and has the potential to enable mass production of flexible electronics.
Researchers are developing a new oral multiple sclerosis drug that targets the molecule miR-326, which stimulates the production of immune system mediators. The drug aims to inhibit miR-326 and block the production of Th17 cells, potentially offering a more convenient treatment option for patients.
A clinical trial found that Souvenaid improved verbal-memory performance in 40% of patients with mild Alzheimer's, while a control group showed deterioration. The nutrient cocktail boosts new synapse formation, potentially reversing cognitive decline.
Researchers found two genetic variations in chickens with potential to fight cancer and bacterial infections, offering new clues for disease treatment. The discovery is based on the examination of NK-lysin, an antibacterial substance that occurs naturally in animals.
A systematic review found that the level of evidence for emergency obstetric referral interventions is poor, making it difficult to determine their effectiveness. The design limitations of individual studies also hindered the assessment of referral interventions.
The ONR Rough Rhino system tracked over 600 vessels of interest during the recent AMLEP operation, culminating in 24 boardings by maritime security teams. The system provided a comprehensive maritime domain awareness picture for dark and light targets.
A University of Toronto study found that the type of relationship consumers form with brands influences their assessment of fairness. In exchange relationships, respectful treatment is more crucial in fair outcomes, while in communal relationships, it has less effect. Marketers must understand these dynamics to correct unfair outcomes.
A new nationwide study by UC Davis examines mortality rates and epidemiological aspects of stray-bullet shootings, finding that most victims were unaware of the events leading to their injuries. The study reveals that nearly one-third of victims were children and nearly half were female.
A new study estimates that contraceptive use prevents more than 272,000 maternal deaths from childbirth each year. The researchers found that satisfying the global unmet need for contraception could reduce maternal deaths by an additional 30%. Effective contraception also averts nearly 230 million unintended births annually.
Remote presence robots enhance critical care physician interactions with patients, leading to improved patient satisfaction. Most surveyed ICU physicians intend to continue using the technology, believing it improves patient care.
Researchers discovered a way to inhibit Taspase1 by 'gluing together' individual molecules, providing a promising approach for cancer treatment. The enzyme plays a critical role in the development of leukemias and solid malignancies, making it a key target for disease therapy.
NASA's GOES-15 satellite captured an image of three tropical systems chasing each other in the eastern Pacific Ocean, with Tropical Storm Daniel and Hurricane Emilia at the center. The system is expected to weaken to tropical depression status by July 11.
Forest soils lose more carbon under elevated CO2 levels, contrary to previous assumptions. The IU-led research reveals that microorganisms play a key role in this process.
Research reveals that copper from brake linings and mining operations impacts salmon's ability to detect predators via their sense of smell. This altered state makes them more susceptible to attack by predators.
The UK Space Agency has launched its Civil Space Strategy, aiming to capture 10% of the global space market by 2030. The strategy focuses on creating new opportunities for industry, bolstering the role of space in the UK's infrastructure, and furthering national space technology.
A University of Illinois researcher is testing a new model for conservation that involves raising awareness among private landowners about invasive species and providing strategies for moderate livestock grazing and controlled burns. The goal is to promote the growth of native wildlife habitats in the Grand River Grasslands, which has ...
The evolutionary block cipher outperforms known cryptosystems in resisting both linear and differential attacks by introducing evolving encryption algorithms. This design feature enhances the system's security and efficiency, making it a promising solution for modern cryptography.
A team of microbiologists at UMass Amherst has made an advance in understanding the replication of parasites like African sleeping sickness and chagas disease. By characterizing key proteins' organization, they discovered a novel mechanism that could lead to the development of new treatments.
Researchers at the University of Michigan have discovered a new single-gene cause of chronic kidney disease, which implicates DNA damage response signaling. The study found that mutations in Fanconi anemia-associated nuclease 1 (FAN1) lead to increased DNA damage and apoptosis in patients with CKD.
Research suggests that adding words related to health and weight on posters, menus, or recipe cards can stimulate healthy food choices among dieters and overweight individuals. This technique has great potential as an intervention to help weight control, as it is unobtrusive, easy to implement, and low in cost.
A recent study found a small but significant risk of Guillain-Barre syndrome following H1N1 vaccination, primarily in individuals over 50 years old. The risk was estimated to be approximately 2 cases per 1 million doses, with most cases occurring within 4 weeks of vaccination.
Researchers from Case Western Reserve University School of Medicine developed a mouse model that mimics the N48K mutation in Usher III, leading to understanding of how deafness occurs. This new model enables exploration of prospective therapeutics to rescue mutant protein localization and hearing.
Research finds that people at risk for early-onset Alzheimer's disease want to know their genetic profile, but struggle with the results. The study also reveals that the general population and those with a family history of late-onset AD tend to be motivated by fear and anxiety when considering genetic testing.
Researchers at Arizona State University improved microbial fuel cell efficiency by modifying cathode materials and adjusting pH levels. By enhancing hydroxide ion transport, they increased power densities and reduced losses in MFC performance.
Two studies found that infants exposed to the H1N1 vaccine in utero did not have a significantly increased risk of major birth defects, preterm birth, or fetal growth restriction. However, adults exposed to the vaccine were at a small increased risk of Guillain-Barre syndrome during the 4-8 weeks after vaccination.
Cloud top temperatures around Hurricane Emilia's eye were measured to be colder than -94F, indicating high-energy storms. NASA's Aqua and Terra satellites tracked the hurricane's rapid strengthening and weakening phases.
A study by Dr. Natalie Loxton found that individuals with high reward sensitivity experience increased pleasure and urge to eat after watching TV commercials featuring junk food. This suggests a link between reward sensitivity and overeating, particularly in response to appetitive cues.
A recent study found that African-American youths living in public housing communities are 2.3 times more likely to use tobacco than their peers. Early interventions, such as smoking cessation programs and addressing depressive symptoms, can help reverse positive attitudes towards tobacco use and reduce the risk of delinquent behaviors.
A new solar photovoltaic thermal (PVT) system has been developed by Queen's University researchers, generating both electricity and heat. The system uses amorphous silicon cells, which require less material, cost less to manufacture, and offer a higher return on investment.
The American Orthopaedic Society for Sports Medicine (AOSSM) recognizes innovative research in orthopaedic sports medicine through various awards, including the Young Investigators Grants, Clinical Research Outcome Grant, Innovative Outcomes Assessment Grant, and O'Donoghue Sports Injury Research Award. The grants provide funding for s...
Researchers found that rats consuming all their sugar solution in the inactive period gained more weight than those consuming it during the active period, despite similar caloric intake. This study suggests that the timing of sugar consumption can significantly affect body weight gain.