Researchers at the University of Cambridge have developed a novel method to objectively measure a person's desire to eat, which could lead to more effective anti-obesity treatments. The method uses brain activity tracking and hand-grip intensity to assess motivation for food rewards, providing a more accurate reflection of true hunger.
Researchers have identified metformin as a potential treatment for epilepsy by reducing the intensity of seizures. The study used fruit fly movement to analyze the effects of dietary modifications on seizure susceptibility. Dr. Kuebler's lab developed a low-cost, video-based method to investigate metabolic causes of seizures.
Researchers have developed a new methodology to measure brain activity in newborns and children, particularly those born prematurely. The technique uses Event-Related Potential (ERP) and is child-friendly, allowing for the investigation of cortical processing of touch and speech sounds.
Researchers at the Georgia Institute of Technology and NASA have developed a simplified approach to the Miller-Urey experiment, which aims to recreate the conditions under which organic molecules could have formed on early Earth. The study successfully forms amino acids, building blocks of life, under primitive Earth conditions.
Researchers at the University of Manchester have developed a novel technique for reprogramming somatic cells into induced pluripotent stem (iPS) cells without using viruses, reducing the risk of tumor formation. This breakthrough could revolutionize regenerative medicine and provide new hope for treating various diseases.
Researchers have developed a precision instrument that can determine water loss in agricultural systems, enabling growers to make informed irrigation decisions and reducing water waste. The system provides real-time data on water use by plants versus evaporation, leading to significant water savings.
Researchers develop method to transmit plant viruses using whiteflies, providing a means of interfering with plant-contamination and cultivating resistant plants. This technique has been published in JoVE's video format due to its difficulty in describing complex details through traditional text-only journals.
The cantilever technology measures drug-bacteria interactions in real-time, detecting rupturing of individual hydrogen bonds and resolving forces of ~10 pN. It offers a sensitive alternative for drug experimentation and early detection of infectious diseases.
Researchers have developed a technique for injecting therapeutics into the nipple to target breast cancer in its most common origin. This method could reduce side effects and enhance effective drug levels, making it a promising treatment option.
A novel technique using ultrasound waves could reveal how abnormal forces lead to osteoarthritis development, enabling targeted intervention programs.
A new technique from Case Western Reserve University's Capadona Lab enables gauging property changes during implantation and measuring on a micro-scale. This allows for crafting devices that can withstand physiological conditions in the brain for longer-term use, solving a major challenge in bioengineering.
Scientists have developed lab-born human tissue structures to study and treat tumor growth, offering a more accurate alternative to animal testing. The new method uses biochemistry and cell types to replicate human conditions, paving the way for personalized medicine.
A new technique enables scientists to target multiple genes in honey bees via RNA interference, allowing for the examination of insulin metabolism's role in food-related behavior. This breakthrough could provide insight into human dietary behavior and potentially lead to gene control over undesirable food choices.
Researchers developed a non-invasive brain stimulation technique using transcranial magnetic stimulation to improve language function in stroke patients with chronic aphasia. The technique demonstrated long-term improvement in language production, enabling continued development of language capacity months after treatment.
A new technique developed by Dr. Fred Helmstetter and his research group studies the brain's reaction to anticipated pain, focusing on the amygdala's role in emotional learning and behavior. The study uses a combination of MRI and MEG to map amygdala activity over time, providing new insights into anxiety disorders and psychopathology.
Researchers can now study song acquisition, storage, and regurgitation in songbirds using MRI, providing parallels to human language acquisition. This technique allows for repeated, long-term developmental measurements of the brain, shedding light on learning, language, and neuroendocrinological plasticity.
Researchers have developed a method to measure human genetic material's health in relation to age, using telomere length as an indicator. This technique could lead to the development of a 'genetic thermometer' to assess patient health.
A new biosensor can detect antibiotic resistance in bacteria in just 10-12 minutes, significantly faster than existing methods. This technology targets antibiotic-resistant Staphylococcus and has the potential to revolutionize the treatment of superbugs.
Researchers use CT scans to recreate detailed 3D models of human hearts, enabling the study of cardiac anatomy and function. This digital library can aid in the design of cardiac devices and improve treatment outcomes.
A new device allows cellphone cameras to take images from fluorescent microscopes and flow cytometers, enabling areas with limited resources to conduct tests such as checking for contaminated water and monitoring HIV positive patients. The device is expected to be helpful in resource-poor countries and fast-paced clinical environments.
JoVE is launching a new environment section to publish cutting-edge methodologies and innovations in renewable energy, sustainable materials, and more. The section aims to promote environmentally conscientious practices and provide a platform for researchers to present greener technology.
The Journal of Visualized Experiments (JoVE) is accepting submissions for its new Behavioral Sciences section. The new section will enable scientists to publish cutting-edge methodologies and innovations in video format.
Researchers have developed a virtual gaming environment to assist blind individuals in improving navigation skills and developing cognitive spatial maps of unfamiliar buildings. The technology uses audio cues and computer-generated layouts to mimic real-world navigation tasks, allowing users to generate accurate mental layouts.
A new non-invasive optical measurement system monitors neonatal brain activity via cerebral metabolism and blood flow. The system, developed by Dr. Maria Angela Franceschini, will allow clinicians to screen for brain injury and monitor injury progression.
Researchers at Johns Hopkins University developed self-assembling particles inspired by origami that can be manipulated to fold and seal or open and close. These particles have potential applications in drug delivery, mechanical sensing, bio-sensing technologies, and more.
JoVE's new Chemistry section publishes a novel experimental approach to study antifreeze proteins, showcasing the potential for these proteins in cryopreservation and tissue preservation. By visualizing dynamic processes, JoVE aims to facilitate reproducible chemistry research.
Researchers developed a portable video-based test to measure language comprehension in toddlers and children with autism. The test, known as IPL, tracks eye movements while watching videos to identify language understanding without relying on verbal responses.
Researchers train honey bees to associate textured surfaces with sugar water, allowing them to analyze how antennal movement corresponds to tactile pattern recognition. The study provides insight into the complex behavior of honey bees and their use of active motion for sensory information.
Researchers at The Ohio State University have developed a method to purify and enrich magnetotactic bacteria, which can produce magnetic nanocrystals. These bacteria are found in aquatic environments worldwide and possess unique properties that allow them to align with the Earth's magnetic field.
Researchers at Boston University developed a novel technique to produce human induced pluripotent stem cells (iPSCs) from peripheral blood, offering an ethical alternative to embryonic stem cells. The method has been published in JoVE and provides a valuable resource for studying rare genetic disorders.
Researchers have developed a new laser-activated bio-adhesive polymer called SurgiLux, which forms low-energy bonds with tissues when activated by light. This technology has the potential to replace traditional sutures in clinical settings, particularly for delicate tissues like neurons or blood vessels.
Scientists have developed a new video protocol to isolate brain tumor initiating stem cells from primary brain tumors, allowing for quick and efficient analysis of target cells. This approach has been effectively used to identify similar stem cells in leukemia patients.
A new video article in Journal of Visualized Experiments uses fMRI to characterize subjective risk assessment while subjects choose between different lotteries. The research aims to understand normal and pathological behaviors, such as substance abuse and over-eating, by examining how individuals evaluate risk.
The Journal of Visualized Experiments has established a Librarian Advisory Board to foster collaboration between academia and hospitals. The board aims to shape the JoVE platform's content and distribution strategy.
A new video protocol has been developed to synthesize durable nanocrystals that can harvest solar energy efficiently. The technique, published in JoVE, focuses on the liquid phase synthesis of two nanocrystals that produce hydrogen gas or electricity when exposed to light.
A new video article in JoVE presents a novel technique to study interactions between HIV-1 and Plasmodium falciparum in cultured human cells. This method allows scientists to explore different parameters of co-infection, enabling better understanding of the cellular level interactions between these two deadly diseases.
A novel procedure in JoVE enables scientists to study the effects of interstitial fluid flow on tumor cells, promoting a better understanding of tumor growth and metastasis. The technique mimics in vivo conditions, allowing researchers to evaluate potential new therapies.
A new video article demonstrates a standardized procedure for harvesting and processing synthetic spider silk from bacteria, improving fiber strength and scalability. The technique has potential industrial applications in industries where spider silk's properties are valuable.
JoVE launches a new section in physics and engineering, featuring experimental disciplines and interdisciplinary fields. The first article showcases a method to fabricate thin-film solar cells, increasing potential by 45% while reducing thickness.
A new invasive imaging technique monitors brain function in patients with diseases such as epilepsy, providing real-time analysis at a higher resolution than current technologies. The procedure uses pre-placed electrodes to image the brain, offering unprecedented insight into its function.
JoVE has standardized pre-surgical steps for eye surgery through video publications, standardizing corneal transplant procedures to minimize waste and risk of tissue rejection. The articles describe simplified techniques for harvesting cornea and retina, as well as critical steps in keratoplasty and endothelial keratoplasty.
Researchers at Temple University and State University of New York Buffalo have published groundbreaking techniques for detecting biological threats using electricity-free devices. The articles, sponsored by the Defense Threat Reduction Agency, provide a safer world by reducing the threat of weapons of mass destruction.
A team led by Dr. Rachel Morgan-Kiss sampled Lake Bonney's ice-covered waters to study the single-celled organisms that inhabit it. These microbes play a crucial role in global climate change, with their mixotrophic metabolism influencing carbon cycling.
Researchers have developed a new radiation therapy method, stereotactic body radiotherapy (SBRT), that shortens treatment time for gynecologic cancers from 5 weeks to just 3 days. This highly specific procedure targets well-defined tumors with focused radiation beams, minimizing damage to healthy tissues.
A new diagnostic tool for tuberculosis (TB) offers improved accuracy and speed, allowing for faster treatment. The Xpert MTB/RIF assay is a fully automated test that determines TB infection and multidrug-resistant strain in under an hour.
Researchers have developed a new technique to visualize fat distribution in lab mice using X-ray computed tomography (CT), allowing for non-invasive and longitudinal studies. This method provides detailed images of fat volumes within the mouse, enabling researchers to study adipose content at high levels.
A team from the University of California, Davis, created an electronic nose that can differentiate maturity of melons, including cantaloupe, in a matter of minutes. The method has the potential to improve produce quality and breeding, benefiting the agricultural industry.
A new study published in JoVE demonstrates a method for using eye-tracking technology to study young children with autism. The research aims to answer questions about how children with developmental abnormalities view the world, including their perception of faces.
Researchers studied judo, a complex and unpredictable sport, to understand how athletes spend their energy. They used a portable gas analyzer and mathematical formulas to determine the relative contributions of aerobic, lactic, and alactic anaerobic metabolism.
Researchers from Clemson University have developed a method to create temporary holes in the membranes of live cells using a standard inkjet printer. This allows them to introduce molecules inside the cells that wouldn't otherwise fit, enabling studies on cell mechanics and responses to mechanical forces.