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Science News for June 3, 2013


Molecular switch for cheaper biofuel

Researchers have identified a genetic mutation that allows fungi to continuously produce enzymes for breaking down cellulose and xylan into sugar molecules. This discovery enables the production of cheap biofuel from lignocellulose, reducing competition with food production and making it more economically viable.

SourceVienna University of Technology·JournalBiotechnology for Biofuels·DateJun 3, 2013

Mosquitoes reared in cooler temperatures more susceptible to viruses that can affect human health

A recent study published in PLOS Neglected Tropical Diseases found that mosquitoes reared in cooler temperatures have weakened immune systems, making them more vulnerable to viral diseases like West Nile fever and chikungunya fever. The research suggests that temperature may play a significant role in the transmission of these diseases.

SourceVirginia Tech·JournalPLOS Neglected Tropical Diseases·DateJun 3, 2013

Technique could identify patients at high risk of stroke or brain hemorrhage

Researchers developed a new method to measure cerebral blood flow in children on ECMO, finding that those who experienced strokes or brain bleeds had significantly higher blood flow rates than normal, two to six days prior. This technique could help physicians predict and prevent complications, with potential lead time for intervention.

SourceNationwide Children's Hospital·JournalPediatric Critical Care Medicine·DateJun 3, 2013

Multiple sclerosis: Back to basics?

Current MS treatments focus on dampening the immune system, but Dr. Peter K. Stys suggests an alternative: addressing nervous system degeneration as a primary cause of the disease. Recent studies indicate that neuronal structures are also damaged in MS.

SourceFaculty of 1000·JournalF1000 Medicine Reports·DateJun 3, 2013

Harper Government and Genome Canada launch new program

The Canadian government has launched a new program, Genomic Applications Partnership Program (GAPP), to move genomics-based solutions from laboratories to the marketplace. The program aims to stimulate investment in projects addressing real-world challenges and opportunities in genomics, with a total investment of $90 million.

PET finds increased cognitive reserve levels in highly educated pre-Alzheimer's patients

Research published in The Journal of Nuclear Medicine found that highly educated pre-Alzheimer's patients exhibit increased neural reserve and compensation, leading to better coping mechanisms. This suggests that education level plays a crucial role in determining cognitive reserve against the disease.

SourceSociety of Nuclear Medicine and Molecular Imaging·JournalJournal of Nuclear Medicine·DateJun 3, 2013

Wayne State researchers seek to determine impacts of differential speed limits on state freeways

Researchers at Wayne State University are conducting a comprehensive study on the impacts of differential speed limits for cars and trucks on Michigan's state freeways. The study aims to determine whether raising truck speed limits would improve safety or have negative effects on air quality, pavement quality, and freight operations.

Chimpanzees have 5 universal personality dimensions

A new personality rating scale for chimpanzees has been developed to address limitations of previous scales. The scale includes 41 behavioral descriptors and was used to assess 99 chimpanzees, showing the personality ratings were associated with differences in behavior.

SourceLincoln Park Zoo·JournalAmerican Journal of Primatology·DateJun 3, 2013

Alzheimer's leaves clues in blood

Researchers at Araclon Biotech have developed a blood test to measure beta amyloid peptides, which are associated with Alzheimer's disease. The test shows a high level of association between peptide levels and the disease, suggesting a potential biomarker for early diagnosis.

SourceKaizo·DateJun 3, 2013

Preventing an immune overreaction

Researchers develop nanoparticles to block immune responses, enabling precise control of the immune system. The study's findings suggest a new approach to treating autoimmune diseases and allergies by targeting specific immune cells.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJun 3, 2013

JCI early table of contents for June 3, 2013

Scientists use antigen-decorated nanoparticles to prevent immune over-reaction in mice, while also developing a potential gene therapy for Mucopolysaccharidosis Type IIIA. Meanwhile, researchers discover a new target for castration-resistant prostate cancer by blocking mutant androgen receptors.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJun 3, 2013

Powerhouse Fire, California

The Powerhouse Fire in California has burned approximately 46 square miles of the Angeles National Forest, destroying at least six homes and damaging 15 more. Evacuation orders are in place for large portions of the fire area, including several communities, as 975 personnel fight to contain the rapidly spreading blaze.

Tiger moths: Mother Nature's fortune tellers

Researchers at Wake Forest University found that tiger moths can detect an increase in a bat's cry rate and sound intensity, triggering the moth's defense mechanism. The study shows that the tiger moth's tymbal can jam the bat's sonar up to 93% of the time, allowing it to evade attack.

SourceWake Forest University·JournalPLOS ONE·DateJun 3, 2013

Dense hydrogen in a new light

New work from Carnegie scientists reveals the details of a surprising new form of solid hydrogen under high pressure and temperature conditions. The research found that hydrogen takes a form with two different types of molecules, one interacting weakly with neighbors and the other forming planar sheets.

SourceCarnegie Institution for Science·JournalPhysical Review Letters·DateJun 3, 2013

Singapore research team identifies new drug target in deadly form of leukemia

A Singapore research team has identified a protein enzyme, MNK kinase, as a key player in the progression of chronic myeloid leukemia (CML) to its deadly terminal stage. The researchers found that targeting this enzyme could help prevent cancer stem cells from developing drug resistance and improve patient survival.

SourceDuke University Medical Center·JournalProceedings of the National Academy of Sciences·DateJun 3, 2013

A grassy trend in human ancestors' diets

A new study reveals that human ancestors began consuming tropical grasses and sedges around 3.5 million years ago, marking a significant shift in their diet. This change is believed to have set the stage for the development of modern diets featuring grains, grasses, and meat from grazing animals.

SourceUniversity of Utah·JournalProceedings of the National Academy of Sciences·DateJun 3, 2013

Women reject sexually promiscuous peers when making female friends

A study by Cornell University researchers found that women view sexually permissive peers more negatively than chaste women, even if they personally have liberal attitudes about casual sex. In contrast, men's perceptions are more dependent on their own promiscuity, with less promiscuous men favoring less experienced men as friends.

SourceCornell University·JournalJournal of Social and Personal Relationships·DateJun 3, 2013

Annals of Internal Medicine tip sheet for June 4, 2013

Researchers found that daily sunscreen use significantly slows skin aging, with a 24% decrease in photoaging compared to discretionary application. In contrast, a survey of 1,820 physicians revealed that only about 43% had basic electronic health record systems and 10% met meaningful use criteria, highlighting challenges in EHR adoptio...

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·DateJun 3, 2013

Turning point for early human diets occurred 3.5 million years ago

A series of scientific papers reveals early human species like Australopithecus afarensis and Kenyanthropus platyops began eating grasses, sedges, and succulents around 3.5 million years ago. The findings show that early humans acquired a taste for C4/CAM plants after their environments seemed similar to their ancestors.

SourceCalifornia Academy of Sciences·JournalProceedings of the National Academy of Sciences·DateJun 3, 2013

'Back to sleep' does not affect baby's ability to roll

A new study by University of Alberta researcher Johanna Darrah found that babies' rolling abilities have not been impaired by the 'back to sleep' campaign. The study of 725 Canadian infants aged one week to eight months confirms that gross motor skills emerge in the same order and at the same ages as 20 years ago.

SourceUniversity of Alberta·JournalEarly Human Development·DateJun 3, 2013

Despite living closer to better hospitals, black patients go to lower-quality hospitals

A study from University of Michigan Health System reveals black patients in segregated areas are up to 96% more likely to have surgery at low-quality hospitals, living nearly twice as close to high-quality facilities as white patients. The results suggest separate but unequal hospitalization patterns exist, with potential solutions inc...

Scientists develop new technique to selectively dampen harmful immune responses

A team from The Scripps Research Institute has developed a new technique to selectively repress unwanted immune reactions without disabling the immune system as a whole. This method exploits a natural mechanism to target B-cells responsible for Factor VIII rejection, preventing an unwanted immune response in mice for several months.

SourceScripps Research Institute·JournalJournal of Clinical Investigation·DateJun 3, 2013

Middle-aged women commonly become ill with stress

A study of 1,500 middle-aged women found that one in five experienced constant or frequent stress, leading to 40% reporting psychosomatic symptoms like muscle aches and joint pain. Single women and smokers were particularly vulnerable to stress, highlighting the need for preventive measures from society.

SourceUniversity of Gothenburg·JournalInternational Journal of General Medicine·DateJun 3, 2013

Evidence mounts that 4 lifestyle changes will protect heart, reduce your risk of death

A large study found that adopting four lifestyle behaviors - a Mediterranean-style diet, regular exercise, maintaining a normal weight, and not smoking - can significantly reduce the risk of coronary heart disease and mortality. The researchers found an 80% lower death rate over an eight-year period among participants who adopted all f...

SourceJohns Hopkins Medicine·JournalAmerican Journal of Epidemiology·DateJun 3, 2013

Galactic knee and extragalactic ankle

The KASCADE-Grande experiment detected a bend in the energy spectrum of high-energy cosmic rays at different energies for light and heavy particles. The study reveals a flattening of the spectrum beyond the knee, indicating extragalactic acceleration, with the ankle structure appearing first in light primary particles.

SourceHelmholtz Association·JournalPhysical Review D·DateJun 3, 2013

Clinicians often wait for 'red flags' before discussing elderly driving

A new study from the University of Colorado School of Medicine found that elderly drivers are often more open to discussing their driving status than clinicians initially thought. The research suggests that health care providers should start conversations with elderly drivers earlier, perhaps at age 65 when Medicare benefits kick in.

SourceUniversity of Colorado Anschutz Medical Campus·JournalJournal of General Internal Medicine·DateJun 3, 2013

New biomolecular archaeological evidence points to the beginnings of viniculture in France

Researchers have discovered biomolecular archaeological evidence of grape wine and winemaking in southern France, dating back to the 6th-5th century BCE. The findings confirm that ancient Etruscan amphoras introduced wine to the region, leading to the establishment of a native Celtic or Gallic vinicultural industry.

SourceUniversity of Pennsylvania·JournalProceedings of the National Academy of Sciences·DateJun 3, 2013

New strategy for defeating neuroblastoma

Researchers at Karolinska Institutet have discovered a promising strategy for defeating neuroblastoma by targeting the MYCN protein. The approach involves inhibiting the MYC gene, which leads to the accumulation of fat droplets in cancer cells and ultimately causes cell death or development into harmless neurons.

SourceKarolinska Institutet·JournalProceedings of the National Academy of Sciences·DateJun 3, 2013

Test to improve stem cell safety

Scientists have developed a safety test for human induced pluripotent stem cells (iPS) that can identify unwanted cells forming tumours and assess cell stability. The breakthrough could improve the quality of iPS cells and lead to safer cell therapies.

SourceCSIRO Australia·JournalStem Cells·DateJun 3, 2013

Early-life risk factors account for racial and ethnic disparities in childhood obesity

A study found that early-life risk factors, such as rapid infant weight gain and non-exclusive breastfeeding, account for the disparity in childhood obesity rates among black and Hispanic children compared to white children. The researchers suggest designing interventions during pregnancy, infancy, and early childhood could help elimin...

SourceMassachusetts General Hospital·JournalJAMA Pediatrics·DateJun 3, 2013

Enzyme from wood-eating gribble could help turn waste into biofuel

Scientists have discovered a new enzyme that can break down wood into simple sugars, which can then be fermented to produce liquid biofuels. The gribble cellulase is extremely resistant to aggressive chemical environments, making it ideal for industrial applications and potentially reducing costs.

SourceBiotechnology and Biological Sciences Research Council·JournalProceedings of the National Academy of Sciences·DateJun 3, 2013

Using science to address farm pollution

An interdisciplinary team will analyze soil, crop, and climate conditions at 75 Midwestern corn farms to identify factors influencing farmers' decisions about environmentally friendly practices. The study aims to reduce water pollution and greenhouse gas emissions from corn farming, with results expected to inform policy approaches.