Researchers at Penn Medicine are studying health care disparities among people with disabilities through the Mrs. A and Mr. B Project, a collaborative effort with Virtual Ability, Inc. The project aims to provide patients with information to make informed decisions about their medical care.
Researchers develop method to transmit plant viruses using whiteflies, providing a means of interfering with plant-contamination and cultivating resistant plants. This technique has been published in JoVE's video format due to its difficulty in describing complex details through traditional text-only journals.
A new study finds that treatment with abatacept appears to halt the course of focal segmental glomerulosclerosis (FSGS) in patients, preventing proteinuria and promoting remission. Abatacept has been shown to be effective in treating patients with recurrent disease and those at high risk for kidney failure.
A team of researchers at Montana State University has verified that microorganisms produce methane by swimming towards hydrogen gas. The discovery sheds light on the movement of biological cells towards hydrogen gas and its implications for climate change, carbon cycle, and early Earth processes.
Researchers have created a method for producing high-quality aluminum nitride (AlN) layers with atomic-scale thickness and at half the temperature of other methods. This breakthrough expands the potential for new advanced specialty materials in next-generation electronics.
Young salmon scatter in all directions after entering the ocean, contrary to previous assumptions that most head north immediately. The study provides critical insights into salmon behavior and factors influencing survival, such as water temperature and predator presence.
A gut hormone test may predict the extent of metabolic improvement caused by gastric bypass surgery. The test measures GLP-1 responsiveness, which varies from patient to patient and correlates with glucose metabolism improvements.
A new estimate suggests that more than 600,000 bats likely died from wind turbine collisions in the contiguous US in 2012. Bat populations are already under stress due to climate change and disease, making this figure particularly worrisome for their already slow growth rates.
Researchers found that inhibiting ion channel TRPC5 limits kidney filtration loss after injury, suggesting a new therapeutic target. The study demonstrates the protective effects of TRPC5 inhibition on kidney function and provides hope for treating kidney failure.
The National Institute of Allergy and Infectious Diseases is sponsoring a Phase I clinical trial for an investigational genital herpes vaccine candidate, called HSV529. The trial aims to test the safety and immune response of the vaccine in adults aged 18-40 with previous HSV-2 or HSV-1 infections.
A recent animal study from Georgetown University Medical Center suggests that 'cold turkey' withdrawal from morphine can trigger a decline in mental health. Researchers found that treating addicted animals with morphine both increased protective CCL5 protein and decreased pro-inflammatory cytokines, suggesting a beneficial effect.
Researchers suggest that specific parts of food can be safe for consumption in individuals with food allergies, and substitutes can be eaten safely. For example, someone with an egg allergy may be able to tolerate egg yolk but not the whites.
A new study reveals that edited RNA and invasive DNA contribute to individual variation in humans by regulating gene expression. The study found a 20% difference in life span and eye color between individuals with varying levels of ADAR activity.
A new scorpion species, Euscorpius lycius, has been discovered in the ancient Lycia region of Turkey, adding to the total of five known species within the genus. The newly found species is relatively small, ranging from 2-2.5 cm in length and has a pale color with darker pedipalps.
Astronomers observed two nearby supernovae, SN 2012im and SN 2013ek, in spiral galaxy NGC 6984 using NASA's Hubble space telescope. The recent image reveals the second star that has exploded, forming a new Type Ib supernova visible near the center of the galaxy.
A new clinical score test for patients with sore throats can reduce antibiotic use by almost 30% and improve symptoms more quickly. The FeverPAIN score considers fever, pus infection, rapid attendance, inflamed tonsils, and cough or cold symptoms to determine if antibiotics are needed.
Nicolas G. Bazan, MD, PhD, receives the Polish Academy of Sciences' Professor Miroslaw M. Mossakowski Medal for his groundbreaking work on neurodegenerative diseases. Bazan's contributions to research on Alzheimer's, stroke, and other conditions have led to the development of multiple patented therapies.
Use of ACE inhibitors can cause a life-threatening allergic reaction in oral allergy syndrome sufferers, characterized by extreme facial swelling and difficulty breathing. Hay fever sufferers often mistake oral allergy symptoms for food allergies, but it's not a food allergy and can be treated with cooked foods.
A new study suggests that asthma inhalers with dose counters can significantly reduce emergency room visits by 55 percent. The study found that patients who use these inhalers are more likely to know if they have enough medication left and receive timely treatment, resulting in fewer severe attacks. According to the American College of...
Researchers have found a rare case where a bone marrow transplant cured a child's peanut allergy. The study suggests genetic modification during immune cell development may play a role in causing allergies.
Former Tropical Depression 30W has re-formed in the Andaman Sea, with a medium chance of redevelopment by Nov 9-10, threatening India and surrounding nations.
Research reveals morphological and genetic evidence for cattle management in north-eastern China around 10,000 years ago. The discovery of an ancient cattle jaw with unique wear patterns and genetic signatures suggests that humans may have started domesticating cows in more regions than previously believed.
Researchers found that diet complexity affects gut bacteria composition, with complex diets promoting beneficial Lactobacillales and simple diets increasing harmful Proteobacteria. The study suggests steroid hormone nuclear receptors play a role in microbiota maintenance.
The NASA TRMM satellite captured detailed data on Super-typhoon Haiyan before it struck the Philippines, revealing sustained winds of up to 195 mph. The storm's extreme power was showcased in the satellite imagery, with a well-defined eye surrounded by moderate rain and multiple rainbands.
The University of Texas at Arlington has been awarded $49 million in grants from the National Science Foundation for sustainable chemistry and engineering projects. Researchers Fred MacDonnell and Qiming Zhang are working on converting carbon dioxide to methanol using solar power and developing more efficient solar cell technologies.
A Vanderbilt study found that women with chronic autoimmune diseases who take immunosuppressive medications during their first trimester of pregnancy are not putting their babies at significantly increased risk of adverse outcomes. The study included over 600 infants and used health plan data from three geographically diverse health pl...
Researchers at the BESIII experiment have observed two new charged charmonium-like states, Zc(4020) and a neutral X(3872), in high-energy collisions. These discoveries suggest the existence of a previously unknown family of four-quark objects.
A new method developed in collaboration with Unisensor A/S can determine the optimal antibiotic treatment for a given bacterial infection within 2-4 hours, reducing the response time by half. This faster diagnosis can help prevent the development of resistant bacteria and shorten disease courses.
Researchers warn of the dangers of neglecting to clean reed instruments, which can lead to Saxophone Lung, an allergic pulmonary disease caused by specific fungi. Proper diagnosis is crucial, as corticosteroids alone are insufficient in treating this condition.
A new study finds that short-term depression therapy through weekly home visits can relieve symptoms in low-income minority mothers, even in the face of poverty and trauma. The intervention improved depressive symptoms for 8 months after treatment ended, with participants regaining a sense of hope and control over their lives.
Anaphylaxis from shrimp allergy is rare in children, affecting only 7.8 percent of cases, according to a study. The most common reactions are angioedema and skin symptoms like hives, with asthma being a potential risk factor for anaphylactic reactions.
Scientists have discovered a novel approach to treating ALS by targeting toxic RNA, which aggregates into foci in the brain. The new therapy uses antisense oligonucleotides to selectively degrade the toxic RNA without affecting normal RNA production.
A team of scientists collaborated with local volunteers to measure dung decomposition across Finland. Large tunnelling Dor beetles were found to remove dung twice as fast as smaller dung-dwelling beetles and earthworms. Climate also played a significant role in dung disappearance.
Researchers at the University of Pittsburgh have developed polymers that 'snap' when triggered by light, converting light energy into mechanical work. This phenomenon enables flexible devices with potential applications in robotics and biomedical engineering.
Researchers have developed a novel type of OLED that shows promise for high conversion efficiencies, potentially leading to cheaper displays. The new compounds can store electrical energy for longer periods, allowing for more efficient light generation and reduced heat production.
A new research project led by Aarhus University scientists aims to improve agricultural production in Ghana using irrigation and biochar. The initiative seeks to increase crop yields, reduce deforestation, and protect the environment while providing more employment opportunities and a better economy for local communities.
Dr. Walter Quan from Cancer Treatment Centers of America (CTCA) presents two new treatment options for previously-treated advanced cancer patients, showing major benefits with minimal side effects. The first treatment involves combination chemoimmunotherapy, while the second utilizes dose-dense outpatient intravenous Interleukin-2.
A study of 264 kidney transplant recipients found that vitamin D supplementation was associated with improved patient outcomes, including lower risk of organ rejection and death. The research suggests that maintaining adequate vitamin D levels may be crucial for optimal health in kidney transplant patients.
A Penn study reveals that low levels of mitochondrial DNA in tumor cells from aggressive breast cancer patients can lead to the development of metastatic properties. The research, published in Oncogene, breaks ground in understanding cancer progression and may offer a biomarker for personalized treatment approaches.
A study by the American College of Allergy, Asthma and Immunology reveals that asthma sufferers allergic to cats has more than doubled over an 18-year period. Those with asthma are also 32% more likely to be allergic to cats than those without asthma.
Research suggests that pregnant women who receive allergy shots may reduce their child's risk of asthma, food allergies, and eczema. Allergy shots, also known as immunotherapy, can modify and prevent disease progression.
A study by Timothy Craig, MD, found that allergy shots decrease anxiety and depression in those allergic to wasp, bee, and ant stings. Allergy shots are the only treatment known to modify disease progression, making them life-saving for severe allergy sufferers.
Researchers found that the immune system's JunB gene causes liver cells to become inflamed during hepatitis, leading to irreversible damage. The study proposes a new mechanism by which AP-1 acts as a double-edged sword in the liver, contributing to both viral defense and disease progression.
A cross-linguistic study found that words signaling problems with understanding, such as 'Huh?', have similar form and function in languages worldwide. This discovery sheds light on the evolution of human communication and the role of universal linguistic devices.
A new study from the University of British Columbia's Sauder School of Business found that people are more likely to donate when their token support is private, not public. Publicly showing support on social media can actually decrease the likelihood of donating later.
The sun recently emitted a powerful X1.1 flare, disturbing the layer where GPS and communications signals travel. Increased flares are common during the sun's peak activity cycle, which is currently ramping up toward solar maximum conditions.
A study by the American College of Allergy, Asthma and Immunology found that children in southeastern and southern states are more likely to develop hay fever. Climate factors such as temperature, precipitation, and UV index contribute to this increase.
Researchers at A*STAR's Institute of Molecular and Cell Biology have discovered an enzyme, Wip1 phosphatase, that plays a critical role in regulating tumour growth. By inhibiting the action of this enzyme, cancer growth can be stunted and tumours can be cured without developing resistance.
Super-Typhoon Haiyan maintained its structure and remained a powerful Category 5 tropical cyclone as it exited the western Philippines. The storm brought heavy rainfall potential and thunderstorms to various regions, with warnings still in effect across the country.
Researchers at Massachusetts General Hospital found that mice lacking TRPC5 were protected from losing kidney filter function following kidney injury. Pharmacological inhibition of TRPC5 also protected animals from protein loss in the urine.
A study found that Boston-area military veterans diagnosed with PTSD experienced flashbacks and unwanted memories after the Boston Marathon Bombing in April 2013. The researchers urge healthcare systems to be prepared to treat individuals affected by such tragedies.
Individuals with a known gelatin allergy can experience mild to severe reactions from the flu shot, including hives, sneezing, and difficulty breathing. Precautions should be taken when receiving the vaccine, such as having a board-certified allergist administer it.
Researchers found that Oxantel inhibits biofilm formation by targeting an enzyme crucial for bacterial growth, offering a potential therapy for periodontitis. Periodontitis is linked to various health risks, including diabetes, heart disease, and certain cancers.
Researchers identified KDM2A as a histone demethylase associated with non-small cell lung cancer. Induced KDM2A expression increased cell proliferation and invasiveness through ERK1/2 signaling pathway activation.
Adult females are more prone to allergies, asthma and autoimmune diseases compared to males, with gender differences changing after puberty. Genetics play a role in determining allergy and asthma risk, with personalized medicine being key to effective treatment.
A TGen-led study reveals TWEAK-Fn14 as a key drug target for preventing cancer spread, particularly brain cancer. Four compounds inhibit the binding of TWEAK to Fn14, including L524-0366, which suppressed glioma cell migration without cytotoxic effects.
Elderly patients who start dialysis after age 75 have a high mortality rate, with half dying within one year. Healthier elderly patients do better than those with declining health.
The CO2CARE EU project has successfully demonstrated the safe and sustainable closure of a CO2 storage site, meeting key requirements for geological carbon capture and storage. The Ketzin pilot site's termination marks the first site to be closed within a scientific project.