A significant link has been found between high levels of exposure to particulate matter by first responders at Ground Zero and the development of kidney damage. Albuminuria, a sign of kidney disease, was significantly higher in those with high exposure levels.
A new study found that kidney failure patients who experienced discrimination and mistrust in healthcare had poorer quality of life. Patients who reported greater medical mistrust and lower trust in their physicians also showed decreased quality of life.
African-American patients with chronic kidney disease have a faster decline in kidney function due to genetic variations, particularly the APOL1 gene variant. The study suggests that reducing the effect of this gene could lead to a significant decrease in progressive kidney and end-stage kidney disease in blacks.
A new Dartmouth study suggests that chronic dieters overeat when their brain regions that balance impulsive behavior and self-control are disrupted. This depletion reduces a person's ability to engage in self-control by reducing connectivity between brain regions involved in cognitive control and rewards.
Recent studies highlight the effects of combination therapy with ACE inhibitors and ARBs on kidney function decline and cardiovascular events. Additionally, genetic variants of the APOL1 gene are found to increase CKD progression in African Americans.
First responders at Ground Zero experienced significant kidney damage after exposure to particulate matter. The study found a linear trend between level of exposure and measures of poor kidney function.
A large-scale online study found that altering task parameters can significantly impact learning rates in cognitive training. The research showed that making tasks more challenging led to greater improvements in spatial recall and attention, with effects being dose-dependent.
A recent study has found that the APOL1 gene variant is independently associated with a more aggressive course of disease, particularly in African-Americans. The variant is linked to twice the rate of CKD progression and loss of kidney function in those with chronic kidney disease.
Lumosity presents new data on measuring cognitive training improvements, finding larger doses lead to greater gains and training gains strongly predict transfer effects. A reliability assessment of the BPT shows it is a powerful tool for evaluating the effectiveness of cognitive training.
Two clinical trials present new hope for treating patients with kidney disease: a phase 2 trial of ZS-9 shows significant reductions in blood potassium levels, while another trial of abatacept plus cyclophosphamide fails to improve renal response in lupus nephritis. Researchers explore these findings at Kidney Week 2013.
A study published in JAMA found that coprescribing calcium-channel blockers with clarithromycin increases the risk of hospitalization with acute kidney injury and hypotension. The risk was highest among patients taking nifedipine, suggesting a need for quality improvement initiatives to mitigate this largely preventable drug-drug inter...
Studies suggest that consuming more fruits and vegetables can counteract the negative effects of dietary acid on kidney health. Research found that individuals with hypertensive nephropathy who received extra fruits and vegetables or an oral alkaline medication experienced preserved kidney health, while those with high dietary acid lev...
Researchers developed a simple dot test called the Triplets Learning Task (TLT) to assess dopamine loss in Parkinson's disease. The test shows promise as a non-invasive way to evaluate dopamine deficiency and may lead to new ways to improve treatment for PD patients.
Two studies present findings that consuming at least two soft drinks per day may increase excretion of protein in the urine, a hallmark of kidney dysfunction. Moderate fructose intake also increases salt reabsorption by the kidneys, which could contribute to diabetes, obesity, and hypertension.
A new study links preeclampsia during pregnancy to a higher risk of developing kidney failure. Researchers analyzed data from Olmsted County, MN and found that individuals with preeclampsia were more likely to develop kidney failure later in life, but this association was attenuated when diabetes and hypertension were considered.
Genetic variants in the APOL1 gene increase the risk of kidney disease progression and end-stage renal disease in African Americans. Approximately 1 in 10 blacks possess high-risk variants, which speed up kidney disease progression and substantially increase the risk of developing kidney failure.
Triferic effectively delivers iron to the body's bone marrow, maintaining hemoglobin levels without rapid flux, a safer alternative to current intravenous injection methods. The study demonstrated its effectiveness in preventing iron overload and iron deficiency in 300 patients with chronic kidney disease undergoing dialysis.