Articles tagged with Myocardial Infarction
Researchers at Emory University School of Medicine identified the role of nitric oxide in protecting the heart from injury. Exercise boosts levels of an enzyme that produces nitric oxide, which is stored in the bloodstream and heart as nitrite and nitrosothiols.
Researchers found that heart attacks between 6am and noon cause a 20% larger area of dead tissue, leading to more severe consequences for patients. This study suggests that time of day can significantly impact the severity of heart attacks.
A study analyzing Swedish data from 1996-2007 found an increase in evidence-based treatments for STEMI, leading to a decrease in death rates at 30 days and one year after a heart attack. The adoption of new treatments gradually decreased variations between hospitals and was associated with improved survival outcomes.
In a large Chinese city, interventional physicians transferred to patients with ST elevation myocardial infarction (STEMI) improved door-to-balloon time and survival rates. The study found that nearly 85% of patients received specialist care within a year, leading to better long-term outcomes.
A new injection has been developed to limit the devastating consequences of heart attacks and strokes, with potential applications in transplant surgery. The injection targets a key enzyme responsible for inflammation, neutralizing its effects and significantly reducing tissue damage.
A new trial shows that standard-dose clopidogrel is as effective as double the dose for preventing cardiovascular events in patients with high on-treatment platelet reactivity. Researchers argue that a personalized approach to antiplatelet therapy may be more beneficial, warranting further investigation.
Researchers found that stable patients who start an exercise program one week after a heart attack experience better heart performance than those who wait. The study suggests that at least six months of exercise is the most beneficial, and early referral to rehabilitation can lead to improved outcomes.
Researchers found that short-term high-fat diets reduced cardiac tissue damage and improved function in animal models. A sudden switch to a regular diet after the 'splurge' period offered prolonged cardioprotection.
Researchers found that a short-term high-fat diet reduced tissue damage in the heart after a heart attack by up to 70%. The study suggests that 'splurges' of high fat consumption may preserve cardiac function. Further research is needed to understand why this protection wears off over time.
Researchers discovered that injecting DKK2 improved vascular regeneration in a mouse model of myocardial infarction. This suggests potential for pharmacological manipulation to treat various vascular diseases.
Loyola University Health System's Heart Attack Rapid Response Team has dramatically improved care for heart attack patients by reducing door-to-balloon times to just 47 minutes.
A preclinical study found VitaKine PCT to significantly enhance cardiac function, increasing ejection fraction by 23%, compared to controls. The therapy contains white blood cells in specific ratios and concentrations, offering a precise approach to treating heart attack patients.
The Society for Experimental Biology and Medicine (SEBM) awarded its Best Paper Awards for articles published in 2010. These awards recognized excellence in Clinical/Preclinical and Translation Research, Experimental Biology, and Interdisciplinary Research categories. The winners were honored at the 2011 Experimental Biology Meeting.
A large study of over 107,000 people in Denmark found that certain insulin secretagogues (ISs) were associated with a higher risk of death from any cause and heart attacks compared to metformin. Metformin was found to be the most effective treatment for preventing cardiovascular diseases.
A new journal, Therapeutic Hypothermia and Temperature Management, explores the use of therapeutic hypothermia to improve survival rates after out-of-hospital cardiac arrest. The therapy has been shown to reduce brain injury risk in approximately 400,000 people who suffer from cardiac arrest annually.
A large multicentre trial found that radial access for coronary angioplasty in patients with acute coronary syndromes does not reduce death, heart attack, stroke, or major bleeding compared to femoral access. However, it significantly reduces complications at the access site and improves patient comfort.
Since 2003, Minnesota hospitals without cardiac catheterization labs have dramatically improved their acute heart attack or STEMI guidelines and protocols. As a result, the state has seen a significant decline in cardiovascular mortality rates, with a 50% decrease from 2002 to 2009.
A landmark study has found that radial access for angioplasty is a safe and effective alternative to traditional femoral access, resulting in fewer vascular complications and similar success rates. The RIVAL trial involved over 7,000 patients and compared radial and femoral access for coronary angiography and intervention.
A regional prevention project involving 10,000 adults has shown a 24% reduction in acute heart attacks in a five-quarter period compared to the previous period of evaluation. The Heart of New Ulm Project combines environmental, peer leadership and individual interventions to prevent coronary heart disease.
Researchers found substantially lower death rates and fewer subsequent heart attacks among patients who waited eight or more weeks after a heart attack. The study's findings suggest new surgical guidelines could help improve patient outcomes.
Patients who have suffered a mini stroke are at twice the risk of heart attack compared to the general population. The study found that the risk of heart attack among TIA patients was about 1 percent per year, double that of people who had never had a TIA.
A recent study by Tufts researchers found that episodic physical and sexual activity are associated with a short-term increase in the risk of heart attacks. Regular physical activity, however, was not shown to have this effect.
A highly sensitive blood test has been shown to detect heart attacks in a third more patients than previous tests, identifying smaller amounts of heart damage. The test has been found to halve the risk of being readmitted to hospital with another heart attack within a year.
A new study found that a more sensitive test for the cardiac biomarker troponin can increase the diagnosis of heart attacks and identify patients at high risk of another heart attack or death. The test was associated with improved clinical management, fewer deaths, and fewer admissions with recurrent MI.
A retrospective cohort study found that patients with retinal vein occlusion (RVO) had an almost two-fold higher incidence of stroke compared to age- and sex-matched controls. The study suggests that RVO may be associated with an increased risk of cerebrovascular accidents but not myocardial infarctions.
Researchers found that ultrafine particles can activate platelets, increasing the risk of cardiovascular disease, particularly in people with diabetes. The study provides new insights into air pollution's impact on heart health, emphasizing the importance of controlling exposure to pollutants for vulnerable populations.
A large-scale study led by the University of Leicester has discovered 13 new genes that increase the risk of heart attacks. The research, known as CARDIoGRAM, involved over 140,000 participants and 167 clinicians from around the world.
A large-scale international study has identified 13 new gene regions that predispose people to heart attacks, doubling the number of known genetic factors. The study's findings suggest that genetic profiling may become a routine part of clinical care in the near future.
A Yale University study found that older adults are unwilling to take medications for heart disease prevention if they have potential side effects, such as fatigue or nausea. In contrast, most participants would take the medication if it had no adverse effects and offered an average risk reduction.
A study found that older adults are willing to take cardiovascular disease prevention medications if the benefits outweigh the risks. However, many participants were unwilling or uncertain about taking medications with mild adverse effects, highlighting the need for emphasis on both benefits and harms in clinical guidelines.
A study published in The Lancet found that air pollution increases the risk of triggering a heart attack by 5%, while cocaine use increases the risk by 23 times. Air pollution poses a significant public health risk, with substantial decreases needed to meet WHO standards.
Medications like Vioxx, Bextra, and Avandia increase heart attack and stroke risk due to fluid retention. The study suggests the FDA should require verification of cardiovascular safety for all medications causing fluid retention.
A study by the University of Michigan Cardiovascular Center found that being a woman does not necessarily increase the risk of dying from treatment for a severe heart attack. However, women tend to be older and sicker at the time of treatment, leading to higher mortality rates.
A new study by Dr. Todd Anderson at the University of Calgary's Libin Cardiovascular Institute has identified endothelial dysfunction as a predictive marker for coronary heart disease. By detecting this marker in patients, doctors may be able to intervene early to prevent the progression of heart disease.
Elderly black patients are more likely to be readmitted to the hospital after a prior hospital stay for heart attack, heart failure, or pneumonia. The study found that racial disparities in health care and hospital care contribute to higher readmission rates among black patients.
A study by researchers at UCLA Stroke Center found that strokes and cardiovascular disease exacted an enormous toll on Hollywood stars. The team identified 30 actors who suffered strokes and 39 heart attacks among Oscar nominees between 1927 and 2009, with women accounting for 60% of stroke victims.
Research from University of Warwick reveals prolonged sleep deprivation increases risk of strokes, heart attacks, and cardiovascular disorders, highlighting importance of getting 7 hours of sleep per night.
New nanoparticles designed to target fibrin in blood clots can be seen with a new type of CT scanner, providing early detection and potential treatment options for heart attacks. This technology has the potential to save lives by quickly identifying unstable plaque and guiding targeted treatments.
A new study found that hospital spending is associated with lower death rates for patients with life-threatening conditions, including heart attacks, strokes, and pneumonia. High-spending hospitals had a 19% lower mortality rate compared to low-spending hospitals.
Researchers have found that RevaTen platelet-rich plasma stimulates cell repair via growth factor release, attracting reparative cells. Studies indicate significant improvements in cardiac function and reductions in scar tissue after treatment with RevaTen PRP.
A new study identifies genetic variants associated with coronary artery disease (CAD) and heart attacks. The researchers found that certain genetic profiles increase the risk of CAD and heart attacks in individuals with CAD, while blood group O offers protection against heart attacks.
Cardiologists at UConn Health Center have identified a protein fragment that can predict heart attack, allowing for earlier diagnosis and potentially life-saving treatment. The discovery could also lead to the development of new therapies to block cell death and preserve heart muscle function.
Researchers found Longevinex, a resveratrol supplement, provides cardio-protection across a wide dosage range without toxic effects. Unlike plain resveratrol, Longevinex exhibits an L-shaped safety curve, minimizing heart damage and optimizing protection.
A recent study published in PLoS ONE found that Longevinex exerts a greater influence on genes than resveratrol, leading to improved heart health outcomes. The research demonstrated that Longevinex reduced the size of heart attacks and protected against cell death, while also improving microRNA activity.
A new blood test can detect cardiac troponin T levels in 25% of seemingly healthy individuals, indicating an increased risk of dying from heart disease. The test's results showed that those with elevated troponin T levels were nearly seven times more likely to die within six years.
A new study found that cardiac troponin T levels detected with a highly sensitive assay are associated with structural heart disease, cardiovascular mortality, and increased all-cause death in the general population. The prevalence of detectable cTnT varied by sex, race, age, and comorbidities.
A University of Cincinnati study reveals that helicopter emergency medical services can delay treatment for STEMI heart attack patients. The study found that only a few patients received treatment within the recommended 30-minute goal, highlighting the need for streamlined systems to reduce transfer times.
A large-scale study found that patients with rheumatoid arthritis have a 60% higher risk of heart attack just one year after diagnosis, with the risk increasing rapidly in the first few years. The study emphasizes the importance of monitoring heart risk from the moment RA is diagnosed.
Researchers found that common genetic variants near aging-related genes influence the production of circular RNAs, which control INK4/ARF gene expression and risk of diseases like heart attack and stroke. Individuals with more of these circular forms have increased INK4/ARF gene expression.
A new study published in Sleep reveals that myocardial infarction can cause paradoxical sleep phase disruption and reduced cholinergic neurons, leading to insomnia. The research highlights the critical role of rapid treatment and preventive measures to mitigate post-infarction complications.
Research found that women who experienced recurrent miscarriage were five times more likely to have a heart attack in later life. Those who had stillbirths were also at increased risk of cardiovascular disease.
Researchers found increased vascular reactivity and decreased endothelial function in women with broken heart syndrome compared to postmenopausal women and those who had regular heart attacks. This unique risk factor highlights the importance of mental stress in ABS syndrome, which may lead to the development of specific therapies.
Researchers from Leicester and Cambridge discovered genetic markers that identify people at risk of developing potentially fatal blood clots. This breakthrough advances ways of detecting and treating coronary heart disease, a leading cause of premature death.
Researchers at Duke University Medical Center discovered a stem cell secreted protein that improves heart muscle repair after a heart attack. The protein, sfrp2, reduces collagen layering and prevents heart failure in study rats.
A Johns Hopkins study of 950 healthy men and women found that nearly 95% of heart attacks, strokes, or heart-related deaths occurred in those with measurable artery-hardening calcium buildup; healthy individuals without calcification had minimal coronary protection. Statin therapy should only be considered for those at greatest risk.
Researchers at the University of Cincinnati have identified a protein called HAX-1 that protects cardiac cells and muscle from damage during ischemia-reperfusion injury. The study found that HAX-1 levels were reduced in hearts after heart attack, but overproduction improved contractile performance and decreased cell death.
Researchers tested genetic variations in 1,262 people with no history of heart disease and found that genetic scores can modify the estimated risk of heart attack. The study suggests that genetic screening may be most valuable for individuals thought to be at intermediate risk using current models.
A new study suggests that fat-derived stem cells can safely improve heart function after a heart attack by reducing damaged tissue, increasing blood flow, and boosting the heart's pumping ability. The treatment was found to be effective in patients with severe heart attacks, but further research is needed to confirm its efficacy.
Researchers found that injecting a platelet inhibitor directly into the heart through a coronary artery may restore blood flow more effectively than conventional administration after a severe heart attack. In contrast, erythropoietin did not reduce heart damage but may increase it in patients over 70 years old. Additionally, measuring ...
Researchers at Mayo Clinic have shown that iron buildup is prevalent in unstable coronary artery plaque, making it a potential marker for risk of myocardial infarction and sudden death. Non-invasive imaging techniques, such as micro-CT scans, may soon be able to detect these plaques, allowing for earlier intervention.