New research from the University of Montreal shows that children with attention problems are more likely to struggle academically. The study found that only 29% of children with inattention difficulties finished high school, compared to 89% without these issues.
A study of 228 patients found that those with high anger levels had a higher risk of cardiac events and lower infarction-free survival. The researchers suggest a multidimensional therapeutic approach incorporating physical, pharmacological, and psychotherapy treatment to address underlying suffering.
A study of 663 advanced heart failure patients found that echocardiographic response (left ventricular reverse remodeling) was a better predictor of long-term mortality than clinical response. Echocardiographic response was independently associated with superior survival, with patients showing good response having a lower risk of death.
A large-scale trial reveals apixaban's superiority over warfarin in preventing stroke and systemic embolism, while also reducing major bleeding and mortality. Apixaban results in a significant relative reduction in stroke and bleeding events, making it a more effective treatment option.
Researchers have created a more precise system for growing cells by replacing neighboring cells and extracellular matrix with synthetics. This approach reduces uncertainty and biological contamination, facilitating the formation of artificial tissues.
The 1001 Genomes Project reveals a vast number of variations in the Arabidopsis genome, including hundreds of genes missing or present in different strains. This flexibility is believed to contribute to the plant's adaptability to various environmental conditions.
A study published in Nature Genetics found that individuals with mutations in the BAP1 gene are susceptible to developing mesothelioma and melanoma. The research suggests that the BAP1 gene mutation may be involved in multiple cancer types, including breast and ovarian cancer.
Producers and writers from popular TV shows like CSI, Breaking Bad, and Buffy are seeking scientific advice to ensure accuracy in their plots involving lab tests and crime scenes. They aim to improve public awareness of chemistry's role in everyday life through collaboration with scientists.
The genome of mesopolyploid crop Brassica rapa has been sequenced and analyzed, revealing a gene space covering over 98% and identifying 41,174 protein-coding genes. The study provides new insights into the evolutionary history of polyploid genomes and offers opportunities for genetic improvement of Brassica oil and vegetable crops.
Excess nitrogen levels in air and water pose significant threats to human health, including respiratory problems and cancer risk. Nitrogen pollution also exacerbates climate change, but reducing it could lessen these impacts.
Researchers found that elevating free radical levels suppresses appetite in obese mice by activating satiety-promoting neurons. This process is driven by hormones leptin and glucose, which signal the brain to modulate food intake.
The Homburg Cream and Sugar study reveals a correlation between triglyceride and glucose tolerance with cardiovascular outcomes in patients with stable coronary artery disease. Postprandial triglyceride levels were found to be strongly correlated with glucose metabolism, particularly in those with normal glucose tolerance.
A study on Mt. Everest climbers suggests that leucine supplementation can help retain muscle mass while burning fat during periods of food restriction. The researchers found that the food item in which leucine was delivered was critical to its effectiveness, and future studies aim to improve the palatability of the supplement.
A team of scientists will explore the deep carbon cycle to uncover information about carbon hundreds of miles below Earth's surface. They aim to convert carbon dioxide into a rock-like material and potentially discover new materials with industrial applications.
Scientists describe an advance in encouraging stem cells to make decisions about their fate using chemically defined surfaces. This technology holds promise for regenerative medicine, including growing organs for transplants and tissues for treating diseases.
Scientists discover large RNAs regulate embryonic development by physically interacting with proteins, suggesting a critical role in developmental decisions. The study reveals that lincRNAs may play similar roles in most cells and could be engineered to target key genes in disease.
A new genome sequence of Brassica rapa, a key crop for vegetable oils, has been successfully completed. This breakthrough will help breeders develop more efficient varieties of oilseed rape and other important crops, ultimately contributing to global food security.
A study published in Nature has decoded the genetic variation of Arabidopsis thaliana, a model plant used in research. By analyzing 19 strains of this plant, scientists have gained insight into its ability to adapt to different environments and climates.
A new analysis of the ASCOT trial has found that statins prescribed to patients in 2003 still lower mortality rates from infections and respiratory illnesses eight years later. The study also shows no significant difference in cancer deaths, but reduced cardiovascular disease fatalities.
A study published in Nature Genetics identified six new genetic variants associated with type 2 diabetes in South Asians. The research found that people of South Asian ancestry are up to four times more likely to develop the disease, affecting around 55 million worldwide.
The PURE study found extreme under-use of proven secondary CVD prevention therapies worldwide, particularly in middle and low-income countries. Common medications like aspirin and statins were under-utilized seven-fold between high and low income countries, highlighting a massive treatment gap.
The PERMIT-CARE trial demonstrates that MitraClip treatment improves NYHA functional class and reverse left ventricular remodeling in approximately 70% of patients. The study shows that FMR reduction with MitraClip is feasible, safe, and leads to substantial improvement in heart failure patients who do not respond to CRT.
The American Chemical Society is hosting a symposium to address the global shortage of scientists with people skills. The event aims to equip scientists with effective communication and charisma skills to inspire students and engage with the public. Key findings include the importance of social skills in science leadership.
Researchers found temperature differences of a few degrees Fahrenheit between parts of individual cells, which may impact health and disease. The study suggests that cells use differences in temperature to communicate, leading to potential new insights into biological mechanisms.
A global study found that 60% of individuals with heart disease and up to half of stroke patients are not taking four effective drug types, with underuse highest in low-income countries. The study suggests improvements in drug use could substantially reduce global cardiovascular disease within years.
A randomized controlled trial found that colchicine significantly reduced the incidence of recurrences and symptom persistence in patients with recurrent pericarditis. Colchicine was also shown to improve remission rates and reduce hospital readmission.
A German team has developed a new non-invasive method to identify heart failure using an electronic nose, which can detect the condition with 89% sensitivity and 88% specificity. The study screened over 250 patients and found that the method was effective in distinguishing between different stages of heart failure.
Scientists have developed a new skin test that can determine the age of wild animals while they are still alive. The test detects advanced glycation end products (AGEs) in skin tissue, providing valuable information for wildlife management and population control.
The first manned mission to Mars poses significant challenges in provisioning astronauts with food, including weight, nutrition, and psychological factors. Bioregenerative systems that involve growing crops could supply food, oxygen, and purify air, while shipping bulk commodities is another option.
A study presented at the ESC Congress 2011 found that high job demands coupled with low job control are associated with increased risk of heart disease and mortality. Working long hours is also detrimental to health, leading to decreased cognitive function and higher risks of coronary heart disease.
A new nuclear power plant design could provide a compact and reliable source of electricity for manned or unmanned bases on the Moon and Mars. The system is designed to operate in various locations such as craters, canyons, or caves, and can generate large amounts of power, approximately the same as powering eight houses on Earth.
Critically ill heart failure patients supported with short-term VADs before urgent transplantation had higher incidence of surgical bleeding, longer bypass times and primary graft failure rates compared to those receiving conventional therapy. Routine VAD implantation in stable patients may compromise transplant outcomes.
A global study by McMaster researchers found that too few patients are using simple, cheap, and proven drugs to prevent heart attacks and strokes. The study, which included data from 17 countries, found significant gaps in the use of these medications, especially in low- and middle-income countries.
The ARISTOTLE trial shows apixaban reduces stroke by 21% and major bleeding by 31% compared to warfarin, without significant increases in bleeding risk. The study's benefits are consistent across various patient subgroups and settings, offering a promising alternative for treating patients with atrial fibrillation.
Researchers developed a method to generate patient-specific heart cells from hair follicles, enabling disease modeling and drug screening. This approach offers an alternative to existing methods using skin fibroblasts or bone marrow cells, which require surgical intervention.
A team of Stanford researchers has developed a sutureless method for joining blood vessels, which appears to be faster, safer, and easier than traditional suturing. The new technique uses a poloxamer gel and bioadhesive to reconnect severed blood vessels without causing inflammation or scarring.
A team of astronomers using CSIRO's radio telescope discovered a small planet made of diamond orbiting an unusual star called PSR J1719-1438. The discovery provides insight into the evolution of binary systems and the formation of 'diamond planets', which are thought to be composed of crystalline material.
Researchers found that inhibiting microRNA-100, a regulatory RNA molecule, can stimulate the growth of new blood vessels in animals with peripheral artery disease. This could lead to potential therapeutic applications for cardiovascular diseases.
Researchers found a significant correlation between pericardial fat thickness and coronary arterial remodeling in patients with coronary artery disease. Patients with higher pericardial fat thickness were more likely to have non-calcified plaque and positive remodeling, which are related to acute coronary syndrome.
Depressed cardiac patients show significant improvements in physical activity levels and HDL cholesterol after an 8-week combined group therapy program. The program, which incorporates principles of cognitive behaviour therapy, helps patients reframe their thoughts about heart conditions and adopt healthier behaviours.
A study published by the European Society of Cardiology found that watching a funny movie can positively impact vascular function, expanding blood vessels and improving cardiovascular health. The research suggests that incorporating laughter into daily life may be beneficial in preventing heart disease.
A phase IIb study found that dalcetrapib did not harm endothelial function or increase blood pressure, and increased high-density lipoprotein cholesterol levels by 31% without altering markers of inflammation and oxidative stress.
Researchers at the University of Leeds have identified an antibiotic that can prevent the formation of amyloid fibrils in proteins. The discovery could lead to new treatments for diseases such as Alzheimer's, Parkinson's, and Type II diabetes.
A study found that ICD patients are living longer, with an average of nine years after implantation. However, right ventricular pacing negatively affects survival rates, while cardiac resynchronization therapy (CRT) improves outcomes.
The American Chemical Society showcased a large number of scientific reports on sustainability and green chemistry at its meeting. Over 150 researchers presented their findings, addressing topics such as water pollution control and innovative solutions for sustainable production.
Researchers at Stowers Institute for Medical Research discovered that oocytes rely on an intracellular flow to push the meiotic spindle into place, setting the stage for asymmetric cell division. This finding may lead to improvements in selecting promising oocytes for in-vitro fertilization.
The new guidelines aim to improve lipid management in patients with cardiovascular disease. Lifestyle interventions, such as diet and exercise, should be the first step in managing lipids.
The new ESC guidelines on peripheral artery disease emphasize the need to assess patients with coronary artery disease for symptoms or asymptomatic atherosclerosis in other vascular areas. The guidelines also highlight the importance of considering multisite artery disease and the overall clinical status of patients.
The number of patients with cardiac problems during pregnancy is increasing, and careful screening for heart disease is crucial. New ESC guidelines recommend regular screenings, appropriate risk assessment, and counseling to minimize complications and ensure fetal and maternal health.
The American Chemical Society honors Keith H. Gibson, Andrew J. Barker, and George L. Trainor for their contributions to personalized medicine and genetic sequencing. The trio developed a new drug that helped pioneer the era of 'personalized medicine' for cancer patients.
The European Society of Cardiology has launched an updated version of its HeartScore application, which provides a more accurate estimate of cardiovascular disease risk. The new tool includes features such as a 'fast track' calculator and a 'risk age' function to help clinicians quickly understand patient exposure to CVD risk.
Gina Turrigiano's concept of synaptic scaling resolves the paradox of maintaining stability and flexibility in neurons. Her laboratory has shown that neurons can 'tune' themselves by adjusting excitatory synaptic strengths to control output, while maintaining relative input strengths.
A new study found that Florida's reefs suffered unprecedented losses of coral species during the 2010 cold weather event, with coral tissue mortality reaching over 40%. This was particularly devastating for shallow and near-shore reefs, where large colonies were hardest hit.
Researchers found a marked decline in Atlantic salmon populations in Spanish rivers, particularly in Asturias, due to increased fishing effort and higher temperatures. The study suggests that conservation measures should be implemented to protect these populations, which are experiencing cyclic fluctuations.
A recent study by Stanford University researchers found that preserving just 9 key sites could protect habitat for 84% of all marine mammal species on Earth. The study identified critical conservation locations off the coasts of Mexico, Canada, Peru, and other countries as areas with high species richness.
A low-cost, hand-held device called Gene-Z is being developed to detect cancer in resource-poor countries. The device monitors microRNAs and other genetic markers to diagnose cancer, providing an affordable solution to the lack of cancer screening resources in these countries.
NASA satellites gathered detailed rainfall measurements and spotted heavy thunderstorms around Irene's center, indicating the storm's power. The storms were dropping rainfall at 2 inches per hour, with hurricane-force winds expected along the eastern U.S. coast.
A team of researchers at the University of Warwick has found a solution to a 40-year-old problem in understanding solar wind turbulence. By analyzing data from the Cluster mission and creating a virtual model, they discovered that turbulence is not affected by the direction of travel of the solar wind, resolving a long-standing issue.
A team of physicists evaluated the UK's caesium fountain clock, achieving an unprecedented level of accuracy. The new method improved uncertainties in Doppler shifts and microwave-lensing frequency shift, reducing errors to 2.3 × 10^-16.
Dutch company Dura Vermeer has developed a floating house technology using light plastic foam and composite materials, allowing for larger structures without losing buoyancy. The innovation has potential to help countries affected by climate change and rising sea levels, such as small island-states.