Researchers have developed a new resource, mirKO, to investigate the role of microRNAs in human health. The resource provides tools to delete specific microRNA genes in mice or cells, allowing researchers to study their significance and biological function.
Researchers have found that de novo protein-altering mutations account for more than 50% of sporadic schizophrenia cases. These genetic errors are present in patients but not in their parents. The study suggests that many more mutations may contribute to the disease, paving the way for new treatments.
Research suggests a bullying climate may play an important role in student test performance and academic success. Schools with severe bullying climates had significantly lower scores on standardized tests.
A collaborative study between UNC and Duke scientists reveals that disruptions in protein signals can lead to improper mitochondrial distribution during cell division, resulting in reduced ATP levels. This finding has implications for diseases such as cancer and neurodegenerative disorders.
A study published in Nature Genetics identified 49 new significantly mutated genes associated with TCC, including eight genes related to chromatin remodeling. These genetic aberrations were found in 59% of individuals with TCC, suggesting a potential role for UTX gene in bladder cancer classification and diagnosis.
Researchers at Berkeley Lab have discovered a way to create strong, heat-resistant aluminum alloys by controlling nanoparticle size and shape. The alloy's properties are highly dependent on the uniformity of the nanoparticles and their stability when heated.
The UMass Amherst team discovered a fundamental property of microbial nanowires in Geobacter sulfurreducens that allows for long-range electron transport. This breakthrough could lead to cheaper, nontoxic nanomaterials for biosensors and solid-state electronics.
Scientists studied brain cells in rats and found that only place cells were sensitive to height, with weak responsiveness. The brain's sense of space is more accurate in horizontal directions, suggesting a flat map of space for altitude.
Researchers developed a cell-based test that can classify chemicals as sensitizing or non-sensitizing, predicting the strength of allergic responses. This alternative to animal testing aims to reduce suffering from skin conditions such as eczema.
Researchers found a novel system involving Pch2 and Orc1 proteins protecting yeast rDNA from inappropriate meiotic recombination. This protective repeat-associated heterochromatin makes the DNA segments near its boundary particularly vulnerable to recombination.