Articles tagged with Myocardial Infarction
Mayo Clinic researchers found that elective angioplasties performed without on-site cardiac surgery capabilities pose no increased risk for patient death or emergency bypass surgery. The study included thousands of patients and showed mortality rates were similar for centers with and without on-site surgery.
Researchers analyzed over 150,000 adult ADHD users and found no significant association between current use of ADHD medications and an increased risk of heart attack, stroke, or sudden cardiac death. Cardiovascular disease rates were similar among new and ever-users of these medications.
Researchers have found that controlling the balance between two proteins can reduce the growth of dangerous cells in arteries. This finding could lead to a lower risk of further heart attacks and improved cardiovascular health.
Researchers found that reducing CXCR4 levels correlated with reduced infarct size and inflammation, but impaired recovery of blood flow and neovascularization. The study suggests that localized approaches, such as injecting stem cells with higher CXCR4 levels or CXCL12 variants, may be more effective in heart repair.
A study using coronary CT angiography found that women are at a significantly greater risk of cardiovascular events than men when experiencing large amounts of plaque build-up or extensive artery narrowing. In contrast, men with non-calcified plaque are at higher risk for major adverse cardiac events compared to women.
A recent study published in the Proceedings of the National Academy of Sciences found that inflammasome amplifies inflammatory responses in the heart, leading to further damage. Pharmacologic inhibition of inflammasome prevents heart enlargement and dysfunction.
Nationwide study reveals that fewer than 10% of heart attack patients transferred from initial hospital to one offering angioplasty are done within the recommended 30-minute timeframe. This delay increases the risk of death, particularly for STEMI patients who require immediate artery-opening procedure.
A study published in Circulation Research found that the size of a heart attack and subsequent left-ventricular function are significantly different based on the time of day onset of ischemia. The greatest amount of injury to the heart occurs when individuals have a heart attack between 1:00am and 5:00am.
A new study by University of Iowa researchers pinpoints CaM kinase as the key player in cardiac rupture. Blocking this protein may help prevent cardiac rupture and reduce death risk. The study also found that activated CaM kinase prompts heart muscle cells to produce an enzyme called MMP9, implicated in heart rupture.
A new stent design has been linked to shortening and deformity in some patients, leading to serious complications. Researchers and clinicians are investigating the issue and working on new recommendations for its use.
A study found that women and young men make up a substantial portion of heart attack patients without known coronary disease. These groups are less likely to receive preventive medications, which could reduce their risk of heart attacks.
A UTHealth study reveals that patients who call 911 for heart attacks arrive at hospitals 30 minutes faster but still have higher mortality rates due to being more critically ill. The study found that those who call 911 are three times more likely to die, highlighting the need for improved pre-hospital treatment.
Researchers found adult stem cells from bone marrow have potential to improve heart function after a heart attack. However, the original two-week timeframe was not favorable, but the concept still shows promise for recovering lost or damaged heart tissue.
Researchers found that carotid artery stenting following prior same-side carotid artery revascularization results in lower incidences of in-hospital death, stroke, and heart attack. The study's findings have the potential to change how carotid artery stenosis is assessed and treated.
A recent Mayo Clinic study found that smoke-free workplaces significantly reduced the incidence of heart attacks and sudden cardiac deaths in Olmsted County, Minn. residents. The study showed a 50% reduction in sudden cardiac death rates after a comprehensive smoke-free ordinance took effect.
A Mayo Clinic study found that stem cells delivered two to three weeks after a heart attack do not improve heart function. The research provides vital information for the field of cell therapy and cautions against seeking stem cell treatment outside the US.
A new clinical trial funded by NIH found that delayed stem cell therapy after a heart attack is safe, but it does not improve heart function six months later. The study suggests future clinical benefits may still be possible.
Researchers found that adding the oral anti-clotting drug rivaroxaban to standard medical treatment for acute coronary syndrome lowered the risk of death, heart attack, or stroke by an average of 16 percent. This improvement in survival rates is comparable to the benefits seen since the introduction of aspirin.
A study by the American Heart Association found that frequent professional tooth scaling can lower the risk of heart attacks and strokes. Participants who received regular cleanings had a 24% lower risk of heart attack and 13% lower risk of stroke compared to those who never received dental care.
A Stanford study found that nitroglycerin's continuous use can lead to increased heart attack severity in rats. Treatment with Alda-1 enzyme activator reduced the detrimental effects of prolonged nitroglycerin use.
A study by the Heart and Stroke Foundation found that women under 55 experience worse outcomes after a heart attack, including more recurrences of chest pain and physical limitations. The research highlights the need for increased awareness of risk factors and symptoms among women to improve their health outcomes.
A new study shows that hospital heart attack death rates are improving, but elderly patients (85+) continue to lack access to specialist care, including emergency coronary angioplasty and vital heart medicines. This highlights the need for improved age-sensitive care to address inequalities in heart health.
A recent study suggests that women's hearts are more prone to damage from small blood vessels rather than major arteries, leading to misdiagnosis and adverse events. Researchers are working to develop new diagnostic methods and treatments tailored to female heart disease patterns.
Researchers have developed a method to grow cardiac muscle cells from human cord blood stem cells, which could lead to new treatment options for patients with damaged hearts. The study found that these cells can be expanded and differentiated into cardiomyocyte-like cells, overcoming the technical hurdle of deriving cardiac muscle-type...
Academics say a study used to justify patient choice in the NHS is fundamentally flawed and misleading. The report highlights errors in the original study and concludes that it does not prove cause or effect between patient choice and death rates.
A Kaiser Permanente study found that increasing high-density lipoprotein (HDL) levels reduced the risk of heart attacks and strokes among patients with diabetes. Patients whose HDL levels decreased had more heart attacks and strokes, with a 11% increase in risk compared to those with stable HDL levels.
A study of 107,018 Medicare patients found that same-day discharge after elective PCI did not increase the risk of death or rehospitalization. Patients who underwent shorter procedures with lower predicted risk were more likely to be discharged the same day.
A new study has identified subtle markers of heart damage hidden in hours of EKG recordings, allowing doctors to identify high-risk heart attack patients. The researchers found that these anomalies can predict patient mortality within 12 months, enabling targeted treatments to save lives.
A recent UCI-led study found that diabetics with high levels of coronary calcium are at a strong risk of heart attacks and strokes. The researchers also discovered that individuals with diabetes or metabolic syndrome without evidence of coronary calcium had cardiac-event risks comparable to those without these conditions.
Researchers at NYU Langone Health identified a hidden cause of heart attacks in women without significant coronary artery disease. Plaque disruption, a rupture or ulceration of cholesterol plaque in a coronary artery, was found to be the mechanism behind myocardial infarction in some women.
Researchers have discovered a potential new biomarker for heart attacks, cardiac myosin binding protein-C (cMyBP-C), which is released into the blood following a heart attack. Elevated levels of cMyBP-C may help diagnose heart attacks more accurately, reducing unnecessary hospital admissions.
Researchers at UCSF found that bone marrow cells used to treat human hearts after a heart attack are impaired due to inflammation caused by the attack. This discovery may lead to new therapeutic approaches to improve treatment outcomes for heart attack patients.
Despite advancements in treating STEMI patients needing emergency artery-opening procedures, delays continue to occur, particularly during transfers between hospitals. Researchers found that 34.2% of patients experienced delays, with the most frequent reasons being referral hospital delays and cardiac arrest.
Researchers at Cleveland Clinic discovered that medicated stents reduce heart attacks and new blockages in vessels beyond the stent. Patients receiving drug-coated stents have a lower likelihood of suffering heart attacks or developing new blockages.
Research finds psoriasis patients are 26% more likely to die from cardiovascular disease and 18% more likely to die from all causes after a heart attack. The study emphasizes the need for a more aggressive approach to secondary prevention of cardiovascular disease in psoriasis patients.
A US study found that many Americans believe only highly effective drugs without serious side effects are approved. Brief explanations to patients about drug benefits and harms uncertainties can help them make better choices. The FDA does not guarantee a large or important benefit from a drug or that all serious adverse effects are known.
A randomized multicentre open-label study found that 24-month duration of dual therapy is no better than six months in preventing adverse cardiac events, but significantly increases the risk of bleeding and transfusion. The study challenges current guideline recommendations.
The European Society of Cardiology promotes primary PCI as the best reperfusion therapy for acute ST-elevation myocardial infarction. Early diagnosis and triage can significantly reduce mortality rates.
A study analyzing medication trials published in high-impact general medicine journals found that surrogate outcomes, composite outcomes, and disease-specific mortality are used, which can be misleading. These outcome measures may not accurately reflect a medication's impact on important clinical outcomes like heart attacks or strokes.
Studies show that ankle brachial index can help identify individuals at high risk of cardiovascular events, while bifurcated prostheses on aorto-iliac lesions may improve PAD treatment outcomes. Early detection and intervention are crucial to managing PAD and preventing serious consequences.
According to a study, nearly all heart attack patients requiring emergency angioplasty are now treated within the recommended time frame, with a significant improvement from less than half the patients five years prior. The median door-to-balloon time has declined from 96 to 64 minutes during this period.
A five-year study by Yale researchers found that nearly all heart attack patients were receiving angioplasty within 90 minutes of hospital admission, with a significant improvement from 44% in 2005 to 91% in 2010. This rapid progress was attributed to nationwide efforts to accelerate treatment and improve care for patients.
A study of over 2,000 people found that high levels of coronary calcium were a better predictor of heart attack and stroke risk than C-reactive protein. The research suggests that statin medication may be unnecessary for some individuals with normal LDL cholesterol levels and low C-reactive protein levels.
A new study suggests that coronary artery calcium (CAC) is a more accurate predictor of heart attacks and strokes than C-reactive protein (CRP) in healthy adults. High CAC scores are associated with a fourfold increased risk of cardiovascular disease, while low scores indicate an extremely low risk of events. Statin treatment may be mo...
Researchers found that limiting drug-eluting stent use to high-risk patients preserves clinical benefits while reducing costs by an average of $401 per patient. The selective use of these stents has saved the US healthcare system around $400 million annually.
A UCLA preclinical study found that Intralipid, a man-made fat emulsion, can prevent extensive heart damage and preserve heart function when used during blood flow return after a heart attack. This discovery may introduce a new way to significantly decrease damage to the heart muscle due to reperfusion injury.
A study found that a 4-day non-denominational spiritual retreat significantly lowered depression in heart patients, while also raising hope. The retreat included meditation, guided imagery, and outdoor activities, leading to immediate improvements in tests measuring depression and hopefulness.
Researchers found that certain traits, such as hypertension and extreme high or low body mass index, are predictive of increased risk of sudden cardiac death. These findings could lead to the development of a risk stratification score to identify patients at greater risk of dying suddenly if they experience a heart attack.
A team of researchers has identified the MYLIP protein as a potential new target for lowering LDL cholesterol levels. The study found that the N342S polymorphism is associated with high total cholesterol and increased LDL receptor degradation in humans.
Research by University of Edinburgh found that ultrafine particles from diesel exhaust fumes can impair blood vessel function, increasing the risk of heart attacks and strokes. The study suggests that environmental health measures to reduce emissions could save lives.
Researchers found that nearly all PCIs (98.6%) for acute indications were classified as appropriate, while only half of those for nonacute indications could be classified as such. The study suggests an opportunity to examine and improve the selection of patients undergoing PCI in the non-acute setting.
A new study found that patients with diabetes who took higher doses of Aspirin (up to 325mg/day) had a 23% lower risk of death from heart attack. Pharmacists can play a significant role in administering this treatment, working proactively with physicians and patients.
A Johns Hopkins-led study suggests that healthy, middle-aged smokers taking varenicline have a 72% increased risk of being hospitalized with a heart attack or serious heart problems compared to those on a placebo. This risk applies even among smokers without pre-existing heart disease.
A new study published in Archives of Internal Medicine found that patients treated for a heart attack in US territories have a significantly higher risk of dying within 30 days. The researchers used Medicare data to compare outcomes in hospitals across the US territories and mainland, revealing substantial differences in mortality rates.
A multicenter study published in Catheterization and Cardiovascular Interventions found that elective unprotected left main coronary artery PCI with drug-eluting stents resulted in favorable outcomes for patients with normal left ventricular function, including low rates of cardiac death and target lesion revascularization. Patients ag...
A study found that only 11% of patients with STEMI receive primary PCI within 30 minutes, leading to delayed treatment and worse outcomes. Patients who received timely transfers were more likely to undergo primary PCI and had better door-to-balloon times.
A new analysis of the PLATO study confirms that ticagrelor is more effective than clopidogrel in reducing death and recurrent heart attack, with a potential to prevent up to 20% of heart-attack related deaths.
A new study found a significant decline in heart attack rates among London civil servants over 20 years, primarily due to improvements in cholesterol levels, blood pressure, and reduced smoking. However, the rise in body mass index (BMI) may reverse this trend in the future.
New research links fear of dying during a heart attack to increased inflammation, which can predict worse outcomes for patients. Fear of dying is associated with larger inflammatory responses and reduced heart rate variability.
Research reveals that individuals with significant mental ill health experience higher than expected mortality rates following acute coronary events such as heart attacks. The study found that these patients receive inferior care, including fewer life-saving interventions and lower rates of essential coronary care procedures.