Researchers at Georgia Tech and Emory University will develop biomaterials to capture molecules from embryonic stem cells for enhanced tissue regeneration in adults. The goal is to harness regenerative power of stem cells without tumor formation or immune system compatibility issues.
Tens of billions committed globally to improve the health of women and children, with over $11 billion from poorest countries. The Every Woman, Every Child effort aims to reduce death tolls and improve health outcomes through policy and service delivery commitments.
Hermann Muller knowingly lied about safe levels of radiation exposure, says UMass researcher Edward Calabrese. Muller's suppression of evidence led to the adoption of a linear dose-response model that has shaped radiation and chemical exposure regulations.
A study found that MRI screenings detected more breast cancer cases than mammography in high-risk, underserved women. The use of MRI also increased patient compliance with follow-up care. Lowering the cost of MRI may make this screening method more accessible to underinsured populations.
Three Johns Hopkins researchers, including Andrew Feinberg, Gyanu Lamichhane, and Thomas Hartung, have received NIH Director's Awards for their groundbreaking work in epigenetics, tuberculosis, and toxicological testing. Their research aims to revolutionize cancer treatment, develop new antibiotics, and improve human health.
A study of over 30,000 cancer patients found that up to one in five risk developing blood clots called venous thromboembolism (VTE), with risks nearly doubling after a year of treatment. VTEs can be deadly and costly, with average care bills exceeding $110,362 compared to $77,984 for non-VTE patients.
A meta-analysis of 28 prospective cohort studies found depression associated with a 45% increased risk of total and fatal strokes. Depression also increases the risk of ischemic strokes by 25%. The study suggests depression may contribute to stroke through various mechanisms, including neuroendocrine and immunological effects.
USDA researchers are exploring high-resolution digital panoramas to study landscape changes in rangelands. By creating detailed images, scientists can track wildlife populations, invasive plant species, and monitor riparian areas.
A study by Children's Hospital of Philadelphia found that optimal sleep duration for teenagers can help stabilize blood sugar levels and insulin secretion. The researchers discovered that 7.5-8.5 hours of sleep per night may protect against the development of type 2 diabetes in obese adolescents.
The Controlled Impact Rescue Tool (CIRT) rapidly rescues those trapped beneath concrete by creating a contained hole with high-energy jolts, making it up to four times faster than traditional methods. CIRT units have been distributed to various search-and-rescue teams across the US.
Research suggests that genetic variations in mRNA and microRNA play a critical role in prostate cancer disparities between African-American and white men. The findings could lead to more specialized treatment options for African-American patients.
A recent study found that older patient age, congestive heart failure, and preoperative neurological problems are independent risk factors for death and complications after spine surgery. The study analyzed data from the American College of Surgeons National Surgical Quality Improvement Program database.
A new plant species, Spigelia genuflexa, with a rare characteristic of burying its seeds has been discovered in the Atlantic forest of Bahia, Brazil. The plant's 'geocarpy' adaptation ensures its propagation by depositing seeds on the ground and sometimes burying them, similar to peanuts.
Jennifer Juarez, a UTHealth doctoral student, has been awarded two research fellowships to study the spread of E. coli, a hard-to-treat bacterium that can lead to food poisoning and fatal disease. Her research focuses on understanding how bacterial cells divide and proliferate, paving the way for novel antibacterial treatments.
Researchers and experts agree on priority research questions focused on problem analysis, interventions, and context-specific support. The study aims to strengthen mental health support in humanitarian settings through tangible benefits.
A team of researchers at McGill University developed a new device that can float over cell surfaces without touching them, allowing for the study of cellular processes such as cancer cell formation and neuron alignment. The device uses quadrupoles to create force fields and deliver molecules selectively to cells.
Researchers have discovered a potential new biomarker for heart attacks, cardiac myosin binding protein-C (cMyBP-C), which is released into the blood following a heart attack. Elevated levels of cMyBP-C may help diagnose heart attacks more accurately, reducing unnecessary hospital admissions.
The Bulletin of Atomic Scientists has published a special issue on the Fukushima Daiichi Nuclear Power Station disaster, featuring articles on the current and future impact of the accident. Experts discuss lessons learned, future responsibilities, and steps to prevent another nuclear tragedy.
Researchers at Stanford University School of Medicine have identified a unique gene fusion in ovarian cancer that could enable early detection and targeted therapies. The fusion, involving genes ESRRA and C11orf20, was found in 15% of aggressive ovarian cancer cases.
A new type of nanoparticle has been developed to deliver chemotherapy drugs more effectively, with a high drug loading capacity and controlled release. The nanoparticle demonstrated significant growth inhibition of pancreatic tumors, showing up to three times higher therapeutic efficacy than traditional chemotherapy drugs.
Researchers at the University of Oregon have developed a new method to account for missing thermodynamic and molecular parameters in molecular dynamic simulations. This approach allows for more accurate predictions of material behavior under various conditions, reducing the need for trial-and-error experimentation. By refocusing inform...
New studies suggest that Arctic sea ice loss is not irreversible, while radiation hazards for spacefarers and air travelers are likely to rise due to solar activity. Researchers also predict an increase in space weather radiation events over the next century.
Two scientists, Dr. Thomas Kosten and Dr. Peter Burkhard, will receive funding to develop a vaccine against methamphetamine addiction and a peptide nanoparticle nicotine vaccine. The vaccines are expected to undergo initial clinical trials within the next five years.
Dr. Douglas A. Mitchell, an Illinois professor, has been awarded the $1.5 million NIH Director's New Innovator Award to develop a generalized toxin-disabling strategy against bacterial pathogens. His approach aims to create drugs that combat pathogenic microbes without promoting antibiotic resistance.
A large, multi-country study found that a fertility-awareness based method of family planning was effective for years. The Standard Days Method, which identifies a 12-day fertile window, showed high effectiveness rates, with fewer than 5% failure rate over three years.
Researchers at the University of Michigan have identified 10 strategies to help patients understand their cancer treatment options and risks. By using plain language, visualizing risk, and considering frequency over percentages, patients can become more fluent in the language of cancer care and make informed decisions.
A Rice University research team is developing a novel system for separating CO2 from power plant smoke stacks. The technology uses waste heat and specialized materials to filter liquids and gases, aiming to significantly reduce energy requirements compared to existing methods.
Researchers at the University of Texas at Austin are developing means to efficiently breed saltwater fish and invertebrates in captivity. Successful breeding has been achieved for seven species, including clownfish, gobies, and coral, reducing reliance on destructive wild-caught methods.
A study published in PLoS Medicine found that early treatment of HIV significantly reduces mortality by 75 percent. The researchers also found that the benefits of early ART outweigh its costs, making it a cost-effective intervention in resource-poor settings.
A recurrent gene fusion between ESRRA and C11orf20 was found in about 15% of serous ovarian cancer cases, suggesting a potential marker for early detection. The discovery sheds light on how these deadly tumors develop and spread.
Research from Cardiff University reveals that invertebrates living on the woodland floor regulate fungal battles, ensuring less competitive species survive. This process maintains soil quality and fertility, supporting native trees and plants.
Researchers have shown they can reverse the aging process for human adult stem cells, which are responsible for helping old or damaged tissues regenerate. The study found that suppressing the accumulation of toxic transcripts from retrotransposons allows for rejuvenation and resetting of 'aged' human stem cells.
Researchers at Stanford Medicine have engineered human heart cells that respond to light, using optogenetics. These light-sensitive cells could lead to a new class of pacemakers and genetically matched replacement heart cells, potentially replacing traditional electrical pacemakers and addressing tissue rejection issues.
Deep brain stimulation (DBS) stimulates specific brain regions to produce new cells that enhance memory. In a mouse study, DBS led to a two-fold increase in new cells in the hippocampus, which improved spatial learning and memory.
The Boltzmann constant has been re-determined by PTB scientists using Dielectric-Constant Gas Thermometry, with an uncertainty of 8 ppm. This achievement demonstrates that DCGT is suitable for determining fundamental constants and brings the country closer to redefining the kelvin unit.
African-American men are up to 3.5 times more likely to have Vitamin D deficiency than Caucasian men, requiring higher supplementation doses. Skin color and sunlight exposure play a crucial role in Vitamin D production.
Geoscience professionals can expect high salaries in the finance and insurance industry, with average aggregated salaries ranging from $102,640 to $82,650. This analysis by the American Geological Institute highlights the varying salary ranges across different industries.
A study by USC, Stanford, and Kellogg School researchers found that individuals with power but low status are more likely to engage in demeaning activities. The study's results support the idea that a combination of power and lack of respect can be toxic, as seen in incidents like Abu Ghraib torture and the Stanford Prison Experiment.
A study in worms has yielded clues about how nerves grow by identifying the molecular mechanisms that prompt dendrite development. The QBI team discovered that a ligand and receptor work together to coax certain neurons to extend dendrites towards their targets.
A new study found that Dutch voters tend to think people who don't cast a ballot support their own party. This phenomenon allows voters and politicians to exaggerate the influence or size of their own party. The researchers suggest that this occurs due to social validation and a desire to promote one's party's success.
A University of Bristol study examined motivational indicators in public and private sector workers across 51 countries. It found that public sector workers tend to be more intrinsically motivated, but corruption levels can affect motivation.
Researchers at Oregon State University have discovered a way to produce 'skutterudites' using microwave technology, cutting production time from days to minutes and opening doors to efficient thermoelectric energy generation. This breakthrough has huge potential for applications in industries and devices that waste heat.
A new study suggests that beta-blocker drugs commonly used to treat high blood pressure may also slow the progression of certain serious cancers like melanoma. The review of thousands of medical records in Denmark found patients taking beta-blockers had lower mortality rates and improved survival times.
A study examining platelet function testing before PCI procedures found that patients with high residual platelet reactivity had a higher risk of ischemic events, including cardiac death and heart attack. The study suggested that tailored therapy using new antithrombotic agents may be necessary for these patients.
Researchers at Brigham and Women's Hospital are studying the role of tissue resident T cells in fighting viral, fungal, and bacterial infections, as well as certain cancers. The study aims to develop vaccines that generate long-lived populations of protective memory T cells.
A recent study published in JAMA found that discussing sexuality with doctors can improve quality of life for prostate cancer survivors. Researchers used phone interviews and questionnaires to measure quality of life in over 2,900 men before and after treatment, including surgery, radiation, or brachytherapy. The study revealed that me...
Researchers at the University of Washington have created a novel proton-based transistor that can communicate directly with living organisms. The device uses protons instead of electrons and has potential applications in biological sensing, prosthetics, and even controlling certain biological processes.
Researchers will analyze social and economic impacts of atmospheric blocking events from the 20th century. They aim to develop new methods for spotting and predicting this rare weather phenomenon, which can trigger extreme conditions such as heat waves and flooding.
A new study published in JAMA Network found that adding cognitive behavioral therapy (CBT) to medication treatment significantly improved symptoms of pediatric obsessive-compulsive disorder (OCD). The 12-week randomized controlled trial involved 124 outpatients between the ages of 7 and 17 years. The results showed that participants wh...
Researchers at Arizona State University are developing strategies to diagnose and prevent two of the most pervasive food-borne microbes, focusing on extraintestinal pathogenic E. coli (ExPEC) and noroviruses. The new initiatives aim to improve food safety and reduce human illnesses, particularly among vulnerable populations.
Scientists discovered that epigenetic modifications in plants, such as DNA methylation, are unstable and often disappear after a few generations. These changes can occur frequently but usually do not contribute significantly to long-term evolution.
Researchers have identified a critical link between p63 and Satb1 genes in regulating skin development. The study found that Satb1 plays an essential role in chromatin remodeling, which is necessary for gene expression and cell differentiation.
A new study found that rain-index insurance can have ecological consequences if farmers adopt unsustainable grazing practices. The study suggests that insurance payouts in periods of moderate drought may incentivize farmers to abandon sustainable management strategies, leading to overgrazing and increased soil erosion. To mitigate thes...
A Finnish study published in PLoS Medicine found that people living alone are more vulnerable to the adverse effects of increased alcohol availability, leading to a substantially increased risk of alcohol-related mortality. The study analyzed data from over 80% of Finland's population between 2000 and 2007 and discovered a greater incr...
A large international study confirms that 11 genetic regions contribute to both schizophrenia and bipolar disorder, with many variations affecting both conditions. The research found strong associations between specific genes and the development of these severe brain disorders.
Typhoon Roke is bringing intense rainfall to Japan, with areas seeing rain fall at 2 inches/50 mm per hour. Heavy rains are already causing rivers to overflow and prompting evacuations for over 1.1 million people in central Japan's Aichi prefecture.
Radionuclide therapy (PRRT) with [177Lu-DOTA0,Tyr3]Octreotate has been shown to improve quality of life and reduce tumor size in patients with gastroenteropancreatic or bronchial neuroendocrine tumors. The treatment has been found to have fewer severe side effects compared to other cancer therapies.
The Society of Interventional Radiology Foundation has accepted a major corporate pledge of $100,000 from the St. Jude Medical Foundation to expand minimally invasive medicine into new areas of discovery. This support strengthens the Discovery Campaign and enables innovative therapies that lead to improved patient care.
Researchers at NOAA and CIRES found that controlled burns during the Deepwater Horizon oil spill released massive amounts of black carbon into the atmosphere, with estimates suggesting 1.4-4.6 million pounds of pollution sent into the Gulf's atmosphere over a 9-week period.
A study by researchers at Albert Einstein College of Medicine found that close supervision by rheumatologists and the use of immunosuppressant drugs can improve the survival of lupus patients with end-stage kidney disease. Patients who visited their rheumatologist regularly had significantly higher four-year survival rates compared to ...
A study found that African-American men living in low-sunlight areas are more likely to have vitamin D deficiency. Researchers recommend stratified recommendations to consider group differences, as skin composition affects vitamin D production.
A new electron microscopy method resolves the structure of tiny crystals, opening up a door to nanostructures. The method is faster and more accurate than conventional methods, allowing for detailed analysis of materials like zeolites and minerals.
More than half of countries are lowering maternal and child mortality rates faster than the global average, with progress particularly strong in sub-Saharan Africa. However, few countries are on track to meet international targets for reducing these deaths, highlighting the need for immediate action.
Research reveals 11 genomic regions associated with mental illness, including six previously unknown areas. The findings provide fresh insight into the causes of schizophrenia and bipolar disorder, potentially leading to new treatment options.
Paul Kenis and James Slauch have been recognized as University Scholars for their exceptional contributions to the field of chemical engineering and microbiology. Their research focuses on developing novel microfluidic tools and studying Salmonella bacteria to understand its virulence and develop new treatments.
The John Theurer Cancer Center is participating in a landmark clinical trial to develop personalized treatments for patients with multiple myeloma. The study aims to accelerate translational research into therapeutic breakthroughs, leveraging genomic portraits and tissue sampling.
A study of over 600,000 Swedish individuals born between 1973-1979 found that preterm birth was associated with increased mortality in early childhood and young adulthood. The strongest inverse association was observed in young adults, particularly for congenital anomalies and respiratory disorders.
Researchers developed prediction models that accurately predict erectile function after prostate cancer treatment based on pretreatment sexual function and patient characteristics. The models found that men who underwent certain treatments had a higher chance of regaining functional erections suitable for intercourse.
Researchers at Tel Aviv University have developed a patented technology that uses bone marrow stem cells to produce neuroprotectors, proteins that shield the brain from neurodegenerative disorders. The treatment has shown efficacy in animal models and is now being tested in human clinical trials.
The University of Alberta's Virtual Reflected-Light Microscopy (VRLM) technology enables geoscientists to analyze ancient sea creatures and date rocks with unprecedented detail. This innovation accelerates species identification of microfossils, used to determine rock age and explore energy resources.
A cost-effectiveness study found that early antiretroviral treatment (ART) is cost-effective in resource-poor settings like Haiti. The study supports the implementation of the new WHO guidelines for early ART initiation, which recommend treatment for all HIV-infected patients with CD4 cell counts below 350 cells/mm3.
Researchers have discovered how living organisms, including humans, protect themselves from carbon monoxide poisoning by altering the structure of haemproteins. This mechanism allows for safe levels of internal carbon monoxide production without impairing cellular functions.
Researchers discovered that precancerous cells in high-risk African-American women consume high amounts of glucose and have activated insulin signaling pathways. Conditions like obesity and gestational diabetes can stimulate these cells, but exercise, weight loss, and metformin may help prevent aggressive breast cancer.
Researchers excavate Channel Islands, Isles of Scilly, and Outer Hebrides to understand the transition from hunting to farming in Britain. The study aims to answer questions about the processes and timing of this significant lifestyle change.
Two Scripps Research scientists, Michael Petrascheck and Brian Paegel, have won the NIH Director's New Innovator Award. Petrascheck will conduct research on aging in C. elegans using $1.5 million in funding, while Paegel will evolve new molecular tools for protein sequencing.
A study by Boston College researchers found that one-third of consumers experience rude treatment from employees once a month. This behavior leads to negative reactions, decreased customer loyalty, and lost profits. Training programs promoting employee civility can help prevent such incidents.
Researchers at Penn State College of Medicine found a way to generate antigen-specific T cells using induced pluripotent stem (iPS) cells, which could lead to a simpler and more efficient method for using the body's immune system to fight cancer. The study, published in Cancer Research, used iPS cells from mice converted into immune ce...
Research from Ohio State University finds that those living in poorer neighborhoods have a higher risk for out-of-hospital deaths caused by coronary heart disease. The study analyzed data from four U.S. communities between 1992 and 2002, finding that lower socioeconomic status was associated with greater mortality rates outside hospitals.
MDC researchers have determined the molecular structure of dynamin, a key player in cellular nutrient uptake. The study provides fundamental insights into the 'wire-puller' mechanism of dynamin during endocytosis, which is essential for signal transmission and immune system function.