Researchers observe helicase enzymes unzipping DNA by manipulating single molecules and observing nucleotide effects. They found ATP can cause unwinding, but only in single-molecule studies.
A Phase III trial demonstrated that the oral recombinant salmon calcitonin tablet OSTORA achieved superior efficacy to nasal calcitonin while showing equivalent safety. This offers a promising new treatment option for postmenopausal osteoporosis patients who have limited options due to side effects or poor tolerance.
A new technology developed by Purdue University researchers allows surgeons to detect small clusters of ovarian cancer cells, leading to improved removal rates. The technique uses a fluorescent imaging agent that 'homed' to cancer cells, illuminating their location during surgery.
The study reveals exactly how dynamin proteins form large assemblies that pinch off bubbles from cell membranes, allowing cells to 'eat' and compartmentalize external items. Understanding these miniature motors may enable the engineering of cells with new functions.
The 'Hacking Autism' initiative selects seven new software applications to be built by volunteer developers, aiming to improve daily life for individuals with autism. The selected apps include social stories, calendar management, medical journals, and communication tools.
Dr Nick Graham, a young researcher at James Cook University, has won the Scopus Young Researcher of the Year Award for his work on predicting fish populations in coral reefs. His research uses satellite data to study the architecture of coral reefs from space, providing valuable insights into how degraded reefs can recover.
Researchers at Brown University found that carbon nanotubes enter cells tip-first and at a 90-degree angle, often causing repeated inflammation. The team's study suggests that understanding how nanomaterials interact with cells is crucial for designing products that help cells rather than harm them.
Scientists have found that nanoparticles can cause brain injury in fish, leading to the formation of vacuoles and nerve cell death. The results may influence policy regulations on environmental protection and human safety.
A breakthrough allows scientists to assemble virtually complete genomes from DNA extracted from a single bacterial cell. This opens the door to sequencing bacteria that cannot be cultured in the lab, including those living on the planet's surface and within human bodies.
A new study found that epilepsy patients who receive additional treatment with antiepileptic drugs have a seven times lower risk of dying from a sudden unexpected death. The study suggests that the reduction in seizure frequency is the most likely explanation for this finding.
A new decision-support model developed by scientists can guide allocation of conservation funding to save more species from extinction. The model incorporates both ecological and economic information, prioritizing conservation activities based on a yearly budget.
Researchers from U of T, KAUST, and Penn State created the most efficient solar cell using collodial-quatum-dots (CQD), achieving record electrical currents and power conversion efficiency. The team's innovative approach eliminated charge traps, enabling rapid electron movement and providing a path to long-term stability.
Researchers have found that taking common medications for dementia does not cause further cognitive decline in those already suffering from the condition. The study involved 224 participants with established Alzheimer's dementia and suggests that low doses of certain medications may be safe for people with dementia.
Research from Autism Speaks Autism Treatment Network found that over half of children and adolescents with autism also have ADHD symptoms, compromising their adaptive abilities and quality of life. The study highlights the importance of identifying and treating ADHD symptoms in individuals with autism.
Researchers developed a noninvasive wireless system to measure breathing rates, alerting caregivers if breathing stops. The technique could increase surgery patient safety and reduce infant mortality by detecting sudden infant death syndrome (SIDS) without invasive monitoring.
A team of gamers solved the molecular structure of a retrovirus enzyme using online game Foldit, achieving results in just three weeks. The breakthrough could lead to the development of new anti-AIDS drugs by targeting specific features on the molecule.
A new study suggests that the planet's deep oceans can absorb enough heat to flatten the rate of global warming for periods of up to a decade. The research, based on computer simulations of global climate, points to ocean layers deeper than 1,000 feet as the main location of the 'missing heat'.
Researchers analyzed gene expression profiles in pigeon crops and found genes involved in cell growth, antioxidant production, and immune response. The study reveals the mechanisms behind pigeon 'milk' production, which is essential for young pigeon squabs.