Researchers found that tumors with high microRNA-200c levels are more likely to spread and those with lower levels may benefit from focused local treatment. This discovery could help identify patients who can benefit from aggressive, targeted radiation therapy and move them away from whole-body treatments.
Genoveva Gonzalez Mirelis analyzed over 2 million map tiles in Kosterhavet National Park to create a spatial distribution of benthic communities, including deepwater corals and Norway lobster. This method can help preserve environments and species for future generations by informing marine planning and regulations.
Researchers developed a new pentrometer to measure apple crispness, improving accuracy and reducing errors in traditional sensory analysis methods. The study found significant correlations between the computerized penetrometer's data and expert panel ratings, demonstrating its potential for large-scale apple breeding programs.
Researchers found common causes of stillbirth to be obstetric complications and placental abnormalities, with previous pregnancy loss also linked to increased risk. The study's findings highlight the need for thorough investigation into cause of death and development of interventions to prevent stillbirths.
Researchers at the Wellcome Trust Sanger Institute have identified two cell surface proteins, Jamb and Jamc, crucial for muscle cell fusion. The discovery sheds light on cellular fusion and its importance in muscle development, potentially leading to new treatments for muscle-wasting disorders.
The Solar Heliophysics Observatory (SOHO) has discovered a new Kreutz-family comet, C/2011 W3 (Lovejoy), through ground-based telescope observations. This is the first time a Kreutz comet has been found in this way since the 1970s, providing scientists with an opportunity to study it before it moves into view of space-based telescopes.
Researchers found that obstetric conditions, genetic abnormalities, and infections were common causes of stillbirth. The study also identified racial disparities in stillbirth rates, with black women more likely to experience stillbirths during pregnancy or childbirth.
Voyager 1 has sailed to the edge of the solar system and is expected to punch its way into interstellar space in the coming months or years. The spacecraft was launched in 1977 and completed the Grand Tour of the Solar System, making numerous groundbreaking discoveries about the outer planets and their moons.
A study found that biopsy referral rates for men with high PSA levels remained stable despite recent recommendations to lower the threshold. Biopsies became slightly less common over time, likely due to growing awareness of overdiagnosis and overtreatment.
Researchers discovered how statins promote the breakdown of plaque by activating a cell surface receptor, forcing macrophages out of plaque. The study supports clinical findings that high-dose statins reduce cholesterol levels and plaque amount in arteries.
Research found that people with myotonic muscular dystrophy are at higher risk for developing four specific types of cancer. Additionally, there may be an increased risk for other cancers such as eye, thyroid, pancreas, and female reproductive organs. Patients should prioritize cancer screening, particularly colon cancer screening.
A study published in JAMA Network found that patients with myotonic muscular dystrophy are at an increased risk of developing certain types of cancer, including endometrial, brain, ovarian, and colon cancer. The study analyzed data from over 1,600 patients and found a significant excess of these cancers compared to the general population.
Contrary to common belief, facial expressions may not be automatic indicators of emotions. Researcher Lisa Feldman Barrett argues that expressions are not biologically basic and cannot be recognized universally. This challenges the traditional view that certain emotional expressions evolved for specific functions.
A new study found that men who are more attractive tend to overestimate women's interest in casual sex, while women underestimate men's desire. This misperception may have evolved as a strategy for increased reproductive success.
A study by Columbia Business School researchers found a significant correlation between time discounting and low FICO credit scores. Participants with better patience scores had significantly higher FICO scores, indicating a potential link between impatience and poorer financial decisions.
A new study on orangutans under dietary stress in Borneo reveals how their adaptation to hard, tough foods may have influenced human evolution. The research suggests that the orangutans' larger molars and more robust jaws developed in response to these challenging food sources.
Researchers at Emory Vaccine Center found that infusing immune cells back into patients after a period of conditioning can revive exhausted cells. This cell-based treatment, combined with an antibody against PD-1, reduced viral levels by a factor of four and made the virus undetectable in some mice.
The Office of Naval Research has selected five new basic research projects for significant funding, focusing on areas such as quantum computing, sensor arrays, and materials science. The programs will receive a four-year award worth approximately $1.5 million annually.
Researchers have introduced a new variety of caladium, 'UF-172', boasting large attractive pink blotches and red petioles, ideal for use in large containers and landscapes. The new variety outperforms existing cultivars in terms of tuber yield potential and container forcing.
A new study reveals that mutations in BBS genes not only control incoming communication via cilia but also outgoing communication via hormone release, leading to restored normal body size, feeding, and metabolism in a small roundworm. This discovery opens up therapeutic avenues for the genetic disorder.
The Leopoldina has completed its refurbishment and will start working from its new offices at Jägerberg 1 in January 2012. The new building provides room for extended staff numbers and space for scientific symposiums and public events.
Researchers at McGill University Health Centre have developed a novel melatonin drug, UCM765, that selectively activates the MT2 receptor in the brain, leading to increased phases of deep sleep. This discovery may pave the way for effective treatments for insomnia, a common public health problem affecting millions worldwide.
Scientists use NASA's Fermi Gamma-Ray Space Telescope to detect high-energy gamma rays from the remnant of Tycho's supernova. This detection supports the notion that supernova remnants can accelerate cosmic rays, providing clues to their origins.
A meta-analysis of studies found that PCIs at centers with and without on-site surgery have similar rates of in-hospital mortality and emergency CABG surgery. However, additional outcome data are still needed to fully understand the risks associated with non-primary PCI at centers without on-site surgery.
A new study by Shane Frederick reveals that people overestimate the average willingness to pay for products, with a bias of +40% across various groups. This overvaluing bias may lead to sellers setting prices too high and difficulties in negotiation.
A recent study by Dr. Christian A. Vaccaro and colleagues found that successful mixed martial arts competitors have distinct ways of managing fear to convey a social identity to others. This 'managing emotional manhood' allows men to evoke confidence, pride, and dominance in their opponents.
A study in the Journal of Consumer Research found that stating an intention to buy a product makes consumers more likely to choose their preferred brand. This motivation narrows their focus, pushing other well-liked brands to the back until the consumer has accomplished the intention.
Researchers at Moffitt Cancer Center have identified a chemical disrupter of the Rb-Raf-1 interaction, which may be vulnerable to targeting to prevent cancer cell proliferation and tumor growth. The study found that this disruption can limit metastasis in test mice, suggesting a potential new approach for combating metastatic disease.
A 5-year study on Bornean orangutans reveals they store fat when abundant food is available and use it for energy during scarcity. This research may aid in understanding human obesity and eating disorders.
A new study published in the Journal of Consumer Research reveals that crowding and accidental touch can negatively impact consumer behavior. Researchers found that customers who were brushed lightly or stood near others but not touched left stores with a negative view of products.
A new study found that most practitioners believe work factors can cause or exacerbate LBP, and recommend a 'short break from work' to allow healing. Despite guidelines encouraging maintaining people at work during episodes of back pain, many clinicians hold contradictory beliefs that influence their clinical decisions.
Researchers found that protein renewal rates vary between proteins according to their role and location within cells. This knowledge could help breed crops incorporating proteins that respond quickly to changing conditions.
Two University of Pittsburgh professors, Anthony Grace and Christian Schunn, have been recognized as AAAS Fellows for their groundbreaking work in cognition and STEM fields. Their research focuses on understanding the mechanisms of schizophrenia and bridging cognitive science research on reasoning and learning in STEM.
Mayo Clinic researchers found that elective angioplasties performed without on-site cardiac surgery capabilities pose no increased risk for patient death or emergency bypass surgery. The study included thousands of patients and showed mortality rates were similar for centers with and without on-site surgery.
Researchers have developed an intracellular, sustained-release drug delivery system using nanoparticles called dendrimers, targeting neuroinflammation in the retina. The treatment protects vision by preventing injury to photoreceptors and reduces neuroinflammation, providing potential relief for millions of patients worldwide.
A new study suggests that small modular reactors (SMRs) could play a significant role in the future of US nuclear power generation. The report concludes that SMRs would be highly advantageous for various sectors in the US, stimulating high-valued job growth and restoring US leadership in nuclear reactor technology.
Rhode Island Hospital is conducting a 5-year study on the effectiveness of cognitive behavioral therapy (CBT) versus supportive psychotherapy for treating Body Dysmorphic Disorder (BDD). The study aims to reduce BDD symptoms and improve daily functioning.
Researchers find that internal group dynamics can lead to biased and misleading scientific findings, affecting the quality of published research. They advocate for improved collaboration practices, including clear goals and roles, to address this issue.
Researchers discovered that submerging azalea cuttings in 50°C water eliminates the deadly fungal disease. The study found that all 12 cultivars were tolerant of short submersion durations, making hot water treatment a viable alternative for disease control.
Researchers develop cost-effective technique for fabricating flexible and stretchable backplanes using semiconductor-enriched carbon nanotube solutions. The technology enables the creation of artificial electronic skin capable of detecting and responding to touch.
Research on low-dose X-ray irradiation reveals significant reduction in aerobic bacteria and mold/yeast populations, while maintaining sugar levels in asparagus. The study found that X-ray treatment can enhance consumer safety by decreasing the number of viable microorganisms.
Researchers at the Wyss Institute have developed a new material called Shrilk that replicates the exceptional strength and versatility of insect cuticle. With its unique mechanical and chemical properties, Shrilk could be used to replace plastics in consumer products, suture wounds, and serve as scaffolding for tissue regeneration.
Researchers created a record-breaking gas mixture of Lithium 6 and Potassium 40 using an ultra-freeze trap, increasing the number of atoms under study to a few billion. This breakthrough will aid in simulating subatomic-scale phenomena and understanding quantum mechanical effects in neutron stars.
A picture book portrays the life cycle and challenges of a threatened frog species in Arizona, sparking enthusiasm for conservation among children. The book, written by an ASU microbiologist, aims to educate kids about biology, ecology, and overcoming obstacles, while promoting conservation efforts.
A new study in Journal of Consumer Research found that online brand comments impact consumer attitudes differently depending on the tone and number of comments. Promotion-focused individuals react to gain-related information, while prevention-focused ones respond to loss-related information.
Researchers from the California Institute of Technology and international partners have achieved a new world record for data transfer at a combined rate of 186 gigabits per second, equivalent to moving two million gigabytes per day. This milestone is crucial for dealing with massive amounts of data coming from the Large Hadron Collider.
Researchers at Tufts University have discovered a novel mechanism regulating stress response in the brain, involving neurosteroids and specific receptors. Blocking these receptors may lead to new approaches for managing stress-related disorders such as depression, epilepsy, and obesity.
A new test developed by QUT PhD student Helen McCosker can predict the likelihood of breast cancer growth, dormancy, or spread to other organs. The test analyzes tissue surrounding cancer cells and offers personalized treatment plans for patients.
A new prognostic model developed by researchers at the University of Texas M. D. Anderson Cancer Center has identified three risk groups for patients with treatment-related myelodysplastic syndrome, each with different survival prospects. The model incorporates multiple factors, including age, cytogenetics, and serum hemoglobin levels,...
A new chemical technique has been developed to deposit a non-crystalline form of silicon into ultra-thin pores of optical fibers. This allows for the creation of more-efficient and flexible optical fibers with hydrogenated amorphous silicon, ideal for applications such as solar cells and telecommunications.
Researchers have developed a vaccine that successfully attacks breast cancer in mice, with implications for treating ovarian, colorectal and pancreatic cancer. The vaccine targets MUC1, a protein found on over 90% of human breast and pancreatic cancer cases.
Researchers at Johns Hopkins University have developed a hydrogel treatment that promotes new blood vessel formation and tissue regeneration, yielding scar-free skin in mouse tissue tests. The treatment has the potential to greatly improve healing for injured soldiers, home fire victims, and others with third-degree burns.
Scientists at NASA's Goddard Space Flight Center are developing a comet harpoon to rapidly acquire samples from specific locations on rotating comets. The harpoon uses a
The American Cancer Society has revised its guideline formation process to prioritize transparency, consistency, and scientific rigor. The new process involves a systematic evidence review, independent writing group, and clear articulation of benefits, limitations, and harms associated with cancer screening tests.
A team of researchers at RUB discovered how the human nose distinguishes between similar smells by analyzing the 3D structure of olfactory receptors and hydrogen bridge patterns. They found a specific pattern of chemical bonds that account for the specificity of olfactory sensors.
A large trial in Ethiopia found that self-epilation using clean forceps is an acceptable alternative to surgery for treating minor trachomatous trichiasis. This approach preserves vision and offers logistical advantages over traditional surgical methods, making it a promising solution for low-resource countries.
A new study published in HortScience finds that the Ridge-Furrow-Ridge Rainwater Harvesting (RFRRH) system with mulches increases soil water content, crop yield, and reduces labor costs. The system also manages weed control without irrigation.
A unique Swedish study of 691 widower men showed that finding a new partner within four to five years of losing their wife significantly reduced the risk of developing depression, anxiety, and sleep disorders. In contrast, those who remained single faced higher risks and were more likely to use sleeping pills and antidepressants.
Researchers from the University of Bristol have discovered a chemical compound in the brain that can weaken synaptic connections between neurons. This finding may provide a potential explanation for memory loss associated with Alzheimer's disease.
A study by Dr Matt Barnes found that two-thirds of workers work at unusual times, limiting their leisure time and social interactions. Older people, particularly those living alone, experience poor social relations and social exclusion, with many spending hours alone each day.
A large study group of Kentucky women found that only 30% were receiving warfarin for atrial fibrillation. The study suggests warfarin anticoagulation treatment is underutilized in this population, but not due to economic or educational disparities.
A recent study found that nostalgia increases both tangible donations and global intentions for charity appeals, suggesting it can foster empathy and encourage charitable behavior. The researchers used five studies to investigate the relationship between nostalgia and charitable giving, with positive results.
Researchers have developed technology using microneedles to detect real-time chemical changes in the body, allowing for continuous monitoring. This innovation could enable personalized medical care and unlock new research opportunities.
Researchers from the University of Guam and Japan are collaborating on a new method for controlling sweet potato weevil pests using Integrated Pest Management (IPM) techniques. The team has successfully developed traps containing fungal spores, which have shown high effectiveness in reducing weevil populations.
A team of scientists at Cold Spring Harbor Laboratory discovered that hydrogen sulfide regulates a signaling pathway implicated in biological malfunctions. H2S modifies an enzyme called PTP1B, preventing it from inactivating PERK, a sensor of unfolded proteins and a critical regulator of cell response to ER stress.
The Radiation Assessment Detector (RAD) is measuring radiation levels on NASA's next rover mission to Mars. RAD characterizes the radiation environment astronauts would experience during a future human mission to Mars.
Researchers at Wayne State University, Mayo Clinic and Johns Hopkins have developed a targeted drug delivery system using nanoparticles called dendrimers. This system reduced neuroinflammation in the retina and protected vision by preventing injury to photoreceptors.
Consumers tend to favor brands that appear on their own Facebook pages, even if they don't consciously notice it. This phenomenon, known as implicit self-referencing, is linked to high self-esteem and positive associations with one's online identity.
Researchers have discovered a protein family known as SWEET that plays a crucial role in transporting sucrose from leaves to other parts of the plant. The discovery could lead to increased crop yields and improved protection against pests, potentially even shedding light on human diseases like diabetes and obesity.
Researchers from the University of Pennsylvania have successfully reprogrammed astrocytes into dopamine-producing neurons, a crucial step towards treating Parkinson's disease. The study demonstrates conversion efficiency of up to 18%, paving the way for novel reprogramming strategies to treat Parkinson's disease.
A recent study found that over 1 in 50 babies are born with a birth defect, significantly more common than previously estimated. The report highlights the need for improved regional monitoring to identify causes and reduce occurrences of anomalies.
Researchers will use a three-year, $1.38 million grant to study presolar grains in a sample of the Murchison meteorite. They aim to extract exceptionally large grains that came from supernovae, allowing them to make more comprehensive measurements and understand how elements were forged.
Researchers have discovered a molecular pathway that can help reduce cardiac damage caused by an enlarged heart, a common result of hypertension or a heart attack. The pathway, activated by stretch of adult cardiac cells, promotes the release of VEGF, which protects cardiac function and keeps cells alive.
Smokers who quit successfully experience noticeable improvements in quality of life, including higher scores on overall well-being and positive emotions. After three years, quitters also report fewer stressors and increased satisfaction with their lives.
A new approach using an HIV drug has significantly reduced the incidence of graft-versus-host disease (GvHD) in blood cancer patients after allogeneic stem cell transplantation. Maraviroc dramatically reduced GvHD in organs such as the gut and liver without compromising the immune system.
Adding biochar to glacial soils reduces carbon dioxide and nitrous oxide emissions. Ethylene production is also stimulated by biochar, potentially influencing plant growth.
Previous research on stillbirth has identified strong associations between reproductive factors, health conditions, and socio-demographic characteristics. The study found that these factors significantly increase the risk of stillbirth, highlighting the importance of early prenatal care and monitoring for women with known risk factors.
Researchers found that buttercup flowers' bright yellow reflection is due to their unique petal structure, which doubles the gloss through two flat surfaces and an air gap. The study provides insight into how flowers attract pollinators like bees.
A study by UC Irvine researchers found that CKD causes depletion of adhesive proteins in the intestines, leading to systemic inflammation and cardiovascular complications. The findings could lead to novel treatments to curb this inflammation and its adverse consequences.
A study found that consumers expect communal principles in churches and pharmaceutical companies, but become outraged when they prioritize commercial interests. Organizations can communicate with consumers by framing their motives as part of their community's shared values.
A new study found that both pre-pregnant weight and weight gain during pregnancy are important predictors of babies' birthweight. Women with higher education levels had the highest offspring birthweight, highlighting the importance of a healthy weight before conception and moderate weight gain during pregnancy.
A new study reveals altered insulin signaling in the pancreas of Type 2 diabetics, resulting in a decrease in beta cell production and quality. The distorted signals disrupt the replication process of beta cells, leading to a major defect in insulin secretion.
A study found that high tau protein levels in fluid bathing the brain are linked to poor recovery after head trauma. Patients with higher initial tau levels had worse outcomes six to 12 months later.
A new study found that individuals with mood and anxiety disorders are more likely to abuse opioids. Non-medical prescription opioid use was associated with an increased risk of developing any mood disorder, major depressive disorder, bipolar disorder, and all anxiety disorders. Early identification and treatment of mood and anxiety di...
The REMOVAL study aims to test whether metformin can prevent or reduce the risk of cardiovascular complications in people with type 1 diabetes. The five-year trial will follow 500 patients and examine the effects of metformin on blood glucose control, treatment satisfaction, and other complications.
Researchers are using mini wind turbines and advanced flow measurements to understand the impact of hilly terrain on wind turbine performance. Preliminary results show that turbines on hilly terrain experience higher wind loads and recover power potential more rapidly than those on flat ground.
Parkinson's disease patients exhibit increased arm swing asymmetry and reduced coordination, which can be easily detected early with inexpensive accelerometers. This method may enhance early diagnosis and treatment opportunities, and researchers plan to further investigate its effectiveness.
A new substance, F-ara-Edu, labels DNA with little to no impact on genome function, allowing for the visualization of DNA synthesis in vivo. This approach enables the identification of virus infection and cancerous growth sites due to abundant DNA replication in these tissues.
The collaboration aims to build on Professor Susann Schweiger's discovery of the mechanism controlling disease-causing protein production. The project seeks to prevent toxic protein buildup in the brain and potentially provide a treatment for Huntington's Disease.