Scientists at Karolinska Institutet found that fat cells in overweight people have a higher capacity for storing fats but a lower capacity for ridding themselves of them. This can lead to an accumulation of triglycerides and cholesterol in the blood, increasing the risk of metabolic diseases.
Researchers successfully grafted deciduous canine teeth and dental pulp stem cells into parent canines, demonstrating bone regeneration after four weeks. The study found increased immunosuppressive activity of these stem cells, paving the way for potential clinical applications in allogenic in vivo stem cell transplantation.
A genomic study identified the SF3B1 gene as frequently mutated in myelodysplasia, a precursor to leukaemia. The mutation is associated with ring sideroblasts and anaemia, leading to more straightforward diagnosis through a single blood test.
Researchers have found that treating mice with OCA-1B, a form of oculocutaneous albinism, with nitisinone improves eye and skin pigmentation. The study suggests that nitisinone could potentially ameliorate vision loss in patients with OCA-1B.
Biologists have discovered that glow-in-the-dark millipedes use their bioluminescence as a warning signal to avoid attacks by nocturnal predators. In the experiment, four times more non-glowing millipedes showed evidence of predation compared to glowing ones.
A study of over 50,000 women found that those consuming two to three cups of caffeinated coffee per day had a 15% decrease in relative risk for depression, while those consuming four cups or more had a 20% decrease. Higher caffeine intake was linked to greater protection against depression.
A new trial suggests that zoledronic acid may extend survival in postmenopausal breast cancer patients by boosting disease-free survival rates. However, the drug's effects on younger women are less clear-cut, with some studies indicating a possible adverse impact on recurrence rates outside bone.
Researchers created a computer model that calculates the probability of benzocaine molecules entering a cell's membrane based on its composition. The model predicts that membranes made mostly of negatively charged phospholipid DPPS present less barrier to benzocaine, leading to safer and more effective use.
A study found that men treated with IMRT had 26% fewer late bowel and rectal side effects than those receiving 3D-CRT. The treatment also showed a statistically significant decrease in acute toxicity.
A study found that pressure reduction foam mattresses and foam cleansers for incontinence care are cost-effective in reducing the risk of bedsores in long-term care residents. The researchers estimated average savings of $115 and $179 per resident, respectively.
A study found that low vitamin B12 levels may lead to brain cell loss and cognitive decline in older people. Vitamin B12 deficiency was associated with lower scores on cognitive tests and smaller total brain volume.
Three NOAA scientists, James Morris, Erin Oleson, and David Richardson, have been recognized for their outstanding work in ecology, whale and dolphin research, and fishery dynamics. Their research has significantly advanced our understanding of invasive species, marine conservation, and sustainable fishing practices.
A recent UCI-led study found that diabetics with high levels of coronary calcium are at a strong risk of heart attacks and strokes. The researchers also discovered that individuals with diabetes or metabolic syndrome without evidence of coronary calcium had cardiac-event risks comparable to those without these conditions.
Researchers from UCLA's Henry Samueli School of Engineering and Applied Science contributed to the development of a comprehensive genetic catalog of 17 strains of mice. The study provides a complete picture of genetic variation in these mouse strains, enabling scientists to accurately predict gene expression levels and identify variant...
Researchers found slower disease progression among patients starting treatment with CD4 counts between 350 and 499. The study suggests initiating therapy at this range may provide long-term benefits, but no benefit is seen for patients with CD4 counts above 500.
Typhoon Nesat is expected to make landfall in the northern Philippines, bringing heavy rainfall, gusty winds, and dangerous surf. The storm has maximum sustained winds near 80 knots (92 mph/148 kmh) and is forecast to cross Luzon and move into the South China Sea.
A UC3M study found that Spanish journalists predominantly use Twitter to publish and distribute information, identify trends, and build audience loyalty. However, only a quarter of respondents use Twitter for investigative reporting.
Researchers at Ruhr-University Bochum developed a new method to calculate the probability of extreme events in finance. The traditional approach ignores the bulk of the relevant data, which can lead to important information being lost. By using this new method, scientists can better predict such events and improve financial models.
A new study published in the Journal of the American Dietetic Association found that consuming brassica vegetables and apples may lower the risk of proximal colon cancer. In contrast, increasing fruit juice consumption was associated with an increased risk of rectal cancer.
Researchers at Harvard University have developed a new device that can trap tightly and efficiently, eliminating the problem of overheating in traditional optical tweezers. The new plasmonic nanotweezers use light from a laser to create strong forces on nanoscale particles.
A new study suggests that implementing stronger tobacco control policies in the Netherlands could save up to 145,000 lives over the next 30 years. The MPOWER report recommends increasing taxes, banning smoking in public places, and providing cessation treatment to achieve this goal.
A new study found that couples counseling can significantly improve the sex lives of prostate cancer survivors and their spouses. The therapy was shown to be effective in improving men's sexual function and satisfaction, as well as enhancing their partner's experience.
Researchers will study the role of folic acid in preventing neural tube defects, with the goal of developing individualized prevention strategies. The study aims to identify which genes are modified by folic acid levels and how those patterns can be used to assess risk for spina bifida.
Patients taking SSRIs with antiplatelet therapy have a higher risk of bleeding compared to those taking ASA alone. The study found that combining an SSRI with ASA increased the risk by 42%, while dual antiplatelet therapy increased the risk by 57%. Women and patients who underwent angioplasty had lower bleeding risks.
A large-scale study found that mothers exposed to certain agents during pregnancy were more likely to have children with asthma. The Danish National Birth Cohort assessed over 42,696 children and found an association between maternal occupation and asthma prevalence among the children at age 7.
The Lancet Oncology Commission emphasizes the need for affordable cancer care in high-income countries by addressing issues like overuse, rapid expansion of demand, and shortening life cycles of medical technologies. The commission suggests value-based pricing, personalized medicine, and education to tackle these challenges.
A team of Seattle researchers has mapped the genome of advanced prostate cancers, identifying 'hypermutation' as a key driver of disease progression and potential resistance to therapies. The study provides clues for early detection and new therapeutic strategies.
Researchers found that teachers of the same race as their school principals have lower turnover rates and report higher job satisfaction. They also receive more administrative support and recognition. The study suggests maintaining diversity in principals to preserve teacher diversity.
A genetic variant in the GLCCI1 gene may explain why some people with asthma do not respond well to inhaled corticosteroids. Researchers found that individuals with two copies of the variant responded only one-third as well to steroid inhalers as those with regular genes.
A recent study published by the University of Exeter found that green turtle eggs laid on naturally hot beaches withstand high temperatures better than those from cooler beaches. This adaptation allows turtles to thrive in hot environments, making them crucial for species survival in a warming world.
A single savings goal is more effective in saving money compared to having multiple goals. This is because it puts individuals in an action-oriented mindset, helping them save more. The study found that multiple goals can lead to people overthinking and making trade-offs, resulting in less savings.
Researchers identified a gene expression profile that can predict prognosis in patients with inflammatory bowel disease. The study found two subgroups of patients, one with mild disease and the other with treatment-nonresponsive disease, which will help physicians identify those who need aggressive therapies.
Researchers have found that distinct gene regulatory networks in the honey bee brain contribute to specific behaviors, such as foraging and aggression. The study confirmed a close relationship between changes in gene expression and behavior, highlighting the importance of understanding the regulation of brain gene expression.
Researchers at NASA developed a flexible memory fabric that can retain information for over 100 days, using copper-oxide fibers as the storage medium. The technology enables e-textiles to detect biomarkers, monitor vital signs, and transmit data to doctors.
New research from the University of Notre Dame shows that holding objects while learning enhances detail processing, but hampers similarity recognition. This orientation to detail has evolutionary roots, with attention to subtleties near the body being crucial for survival.
Researchers at Wake Forest Baptist Medical Center have identified 16 genes involved in iron metabolism that provide better prognostic information than conventional markers. These genes, known as the Iron Regulatory Gene Signature, convey valuable information about breast cancer outcomes.
Researchers have created a new technique that accurately maps the surface composition of tiny Janus nanoparticles, allowing for better evaluation of their effectiveness in various applications. The breakthrough enables production of cleanly segregated particles, which are potentially more valuable than chemically uniform ones.
A daily pattern of rising and falling amyloid beta levels in spinal fluid echoes the sleep cycle, with younger individuals exhibiting stronger highs and lows. As people age, this pattern flattens, potentially providing an opportunity for the body to clear away the Alzheimer's marker.
A new study found that 38% of patients with chronic conditions changed their preferences for CPR and mechanical ventilation over a year. Patients' decisions are influenced by factors such as health status, mobility, anxiety, and depression, highlighting the need for regular re-evaluation of advance care planning.
Researchers have discovered a compound that destroys several viruses, including the deadly Spanish flu, by activating a human antiviral protein called REDD1. This finding offers new hope for treating flu strains resistant to anti-influenza drugs and could potentially lead to the development of a new drug.
A study from Tufts University found that social status cues can alter the perception of race, revealing a complex process influenced by context and pre-existing stereotypes. The researchers used computer simulations to demonstrate how subtle effects of status cues emerge in a system similar to the human brain.
The report highlights the urgent need for simplified and integrated patient treatment pathways, new models of care with lower cost bases, and a whole new approach to expensive interventions. Radical action is required to make cancer care fair and affordable for all citizens.
Hurricane Hilary is experiencing its heaviest rainfall in the northwest quadrant, with rain falling at 2 inches per hour. The storm is also showing signs of strengthening, with cloud tops cooling and towering clouds indicating increased power.
A study found that men over 75 with prostate cancer are being undertreated, while those with a single comorbid condition are being overtreated. The study suggests that individual medical problems impact survival more than age alone.
The article explores the ethics of gallows humor in medicine, with author Katie Watson arguing that some joking between medical professionals can be beneficial. She suggests that the key to deciding when gallows humor is okay lies in understanding the intent and impact of jokes on patients and power dynamics.
The Texas Advanced Computing Center announces the deployment of Stampede, a world-class supercomputer with comprehensive computing and visualization capabilities, made possible by a $27.5 million NSF grant. The system will support over 1,000 projects in computational and data-driven science, enabling researchers to explore complex phen...
A Wayne State University professor is developing multifunctional therapeutic agents to slow Parkinson's disease progression and alleviate symptoms. The research aims to promote survival of dopamine neurons, which degenerate in the disease.
The Autism Speaks Autism Treatment Network has received a $12 million federal grant to continue its work in supporting clinical research, developing best-practice guidelines, and providing tool kits for families and physicians. The funding will also support the development of additional research within the ATN, including clinical trial...
A LSU research team found dramatic biological responses in fish exposed to oil constituents, even at very low concentrations. Genome expression and tissue damage indicate potential reproductive impairment and developmental abnormalities.
A newly identified DNA repair defect may leave some young leukemia patients less likely to benefit from chemotherapy, increasing the risk of relapse. The study found low levels of a key protein and missing regulatory genes in leukemia cells, suggesting a potential new marker for high-risk patients.
Researchers found that ground beetle larvae use a unique method to attract and feed on amphibians, tricking them into thinking they are tasty prey. This phenomenon has significant implications for understanding the environmental impact of invasive species.
Researchers at Case Western Reserve University found that African-American women develop functional health challenges earlier than others, with a faster rate of reported physical limitations. This disparity is linked to intersectional factors such as gender, race/ethnicity, education, and socioeconomic status.
A game-changing catalyst has been discovered by University of Alberta researchers, offering a potential solution to the chemical industry's environmental and economic challenges. The new catalyst produces minimal waste and can achieve multiple turnovers, reducing the industry's ecological footprint.
Researchers explore how 'Uncle Tom's Cabin' has been referenced and reinterpreted in over 100 films, plays, and musicals, revealing shifts in attitudes towards African Americans. Sharon Dean's research highlights the evolution of representations, from demeaning stereotypes to more sympathetic portrayals of diverse groups.
Two key Southern California fisheries have collapsed due to a combination of overfishing of spawning areas and changes in oceanographic conditions. The study found that despite stable catch rates, the population sizes of barred sand bass and kelp bass decreased by 90% since 1980.
A study of 1,520 patients found that those with asthma admitted to hospital with H1N1 had less severe outcomes, including lower mortality rates and fewer intensive care needs. This was attributed to prompt admission, appropriate treatment, and regular inhaled steroid use.
A large-scale review of DBE found a pooled detection rate of 68.1% for all small intestinal diseases, with inflammatory lesions and vascular lesions being the most common findings in suspected mid-gastrointestinal bleeding patients. The study concluded that DBE is a valuable modality with acceptable detection and complication rates.
A new study by the University of Michigan Health System found that subtle non-verbal clues exert an influence on medical care, with patients relying on these cues to evaluate the doctor-patient relationship and doctors using them to inform their medical judgments. The study's method shows promise for improving medical decision making.
Physicists from the University of Pisa and the Consiglio Nazionale delle Ricerche have put an end to the debate on the glass transition temperature of water. They found that the magic number is approximately 136 Kelvin (-137 Celsius) using a thorough study of water's dynamics, supporting traditional views and refuting recent claims.
Research identifies a new gene regulatory region on chromosome 17 involved in testicle formation in individuals with XX or XY chromosomes. The discovery sheds light on the complex mechanism of human sex development, revealing a missing link in the testis development system.
Rommie Amaro, UCI assistant professor of pharmaceutical sciences and computer science, has been selected by President Obama for the Presidential Early Career Award. Her work employs large-scale computing resources to discover new drugs and explore complex biological mechanisms.
Researchers have determined the architecture of the mitochondrial RNA polymerase, revealing its molecular copy machine mechanism. The discovery provides new insights into the evolution of mitochondria and their genome, shedding light on how they produce energy for cells.
Researchers at Rush University Medical Center found a link between low vitamin B12 levels and reduced brain volumes in older adults. Cognitive tests revealed lower scores among participants with high vitamin B12 deficiency markers.
A study by Columbia Business School researchers finds that women's lower negotiation outcomes are driven by heightened concerns about social backlash, rather than a lack of capability or motivation. To address this, training programs should focus on coaching role shifting and reframing self-advocacy as other-advocacy.
A new 'CAP50' regimen combining chemotherapy and radiation before surgery shows promise in reducing rectal cancer recurrence risk by 88% three years after treatment. The study found that the increase in radiation dose did not extend treatment duration, while avoiding side effects.
Researchers from Boston University Schools of Medicine and Public Health are part of a $10 million grant to examine the consequences of alcohol on HIV disease. The study aims to understand how alcohol affects HIV clinical manifestations and develop more effective treatments.
A study by CSHL and USC researchers reveals that methylation patterns are dynamic and can influence cell fate. The team observed that subtle changes in methylation within specific regions can lead to the activation of genes associated with particular cell types, challenging traditional views on epigenetics.
A recent study by Brigham Young University researchers found that electoral vulnerability and Twitter use are unrelated, with age and party leadership encouragement being key factors. The majority of Congress members use Twitter, but many delegate their accounts to staff, who post links to speeches and interviews.
Researchers at Delft University of Technology have developed a cheap and efficient quantum dot solar cell by understanding electron movement in linked semiconductor nanoparticles. The discovery was published on Nature Nanotechnology, paving the way for more sustainable energy solutions.
University of Texas at Austin researchers have discovered an optimal algorithm to extract information from individual images to determine focus error. This breakthrough could improve auto-focusing in digital cameras and deepen understanding of human depth perception.
The university aims to help students address fundamental issues of sustainability in vehicle design and development. The GATE Center will integrate graduate education and research to overcome technology barriers, fostering an engineering workforce capable of commercializing advanced automotive technologies.
A powerful X1.9-flare has been recorded from sunspot 1302, which is growing and showing no signs of quieting down. The flare could deliver a glancing blow to Earth's magnetic field on September 26.
A recent study found that mutations in the SF3B1 gene are associated with a milder form of myelodysplastic syndromes (MDS) and better overall survival rates. The researchers also discovered a close relationship between the mutated gene and the presence of ring sideroblasts, abnormal precursors to red blood cells, which can cause anaemia.
Researchers identified human cytomegalovirus as a potential target for treating medulloblastoma. The antiviral drug valganciclovir reduced tumor cell growth in both vitro and xenotransplantation in mice.
Researchers found that invasive species like the European green crab may have a major advantage when starting at the upstream edge of their range, particularly in environments with strong prevailing directions of water or wind currents. This can help inform control efforts and conservation strategies for native species.
Researchers at UCLA discovered that a gene variant can predict the success of naltrexone treatment for alcoholism in Asians. The OPRM1 gene variant is associated with better clinical outcomes when taking naltrexone, making it an effective medication option for this population.
A recent article in Nature Chemistry outlines why chemistry has a tarnished public image, citing 'chemophobia' as the reason. The authors propose five communication strategies to improve public engagement with chemistry, including practice research-driven communication and framing key messages to prompt engagement.
This emerging technology uses diffusion tractography to visualize white matter in the brain, offering a new window into human brain anatomy. Recent developments may tackle limitations and challenges, revealing the architecture of the human brain and its breakdown in disease.
Researchers at Salk Institute have discovered how a hormone turns on molecular switches inside the pancreas, increasing insulin production. The finding raises the possibility of new designer drugs to help Americans with type 2 diabetes or pre-diabetic insulin resistance.
Researchers at the University of Missouri have identified a key communication breakdown between nerves and muscles that may lead to new treatments for spinal muscular atrophy (SMA) and other motor neuron diseases. The study found that nerve signals are disrupted before reaching muscle ends, which could inform targeted treatments.
Researchers at Cruces Hospital describe a new syndrome of limited family intellectual disability caused by the duplication of the RPS6KA3 gene. This discovery highlights the importance of genetic research in understanding rare conditions, particularly those with limited intellectual impairment.
A team of professors has received $1.5 million to study a groundbreaking idea that could revolutionize the electronics industry by reducing power consumption and increasing computing speed. The approach involves encoding information using collective states formed by charge-density waves, which can help reduce energy needs per computation.
Researchers at NYU Langone Health identified a hidden cause of heart attacks in women without significant coronary artery disease. Plaque disruption, a rupture or ulceration of cholesterol plaque in a coronary artery, was found to be the mechanism behind myocardial infarction in some women.
Researchers found that passive viewing of 2D images can lead to sustained changes in nerve cell connections, facilitating the expression of persistent hippocampal long-term depression. This discovery has implications for developing strategies to improve digital learning and reduce apathy towards traditional teaching methods.
A survey of US primary care physicians reveals that nearly half believe their patients receive too much medical care, while 52% think the amount is just right. The authors suggest that reimbursement systems should encourage longer visits to reduce pressures on physicians.
Researchers at Michigan State University have created a new malaria vaccine that combines an immune-stimulating gene with a disabled cold virus, increasing the immune response against the parasite. The vaccine was found to be more effective than previously developed systems in animal models, paving the way for human clinical trials.
Christian Bauer and Feng Wang are among 13 DOE PECASE winners, recognized for pioneering research on ultrafast optical characterization of carbon nanostructures. They were awarded the prestigious award for their contributions to advancing sustainable energy, protecting human health, and revealing the origin and fate of the universe.
Patients with uncontrolled diabetes saw faster blood glucose, blood pressure, and cholesterol level control with more frequent primary care visits every two weeks. The study found that doubling the time between physician encounters increased median times to reach treatment targets by 35-87%.
New research suggests that prenatal exercise improves brain plasticity, decreases toxic protein deposits and inflammation in mice, which wards off Alzheimer's disease. Exercise during pregnancy may have a lifetime benefit for the health of newborns.
Alean Al-Krenawi's project aims to bring together Israeli and Palestinian human service providers to facilitate reconciliation and forgiveness. The program will teach tools and techniques to promote understanding, tolerance, and forgiveness in the volatile region.
The researchers aim to create a flexible power distribution system that can adapt to changes in rooftop solar panels. They are developing a holonic multiagent system that can monitor the power grid and negotiate with other agents to maintain balance between loads and generation.
A study by Concordia University and the University of Manitoba found that most boys aspire to have an average physique rather than an idealized, lean, or muscular body. The research suggests that boys are critical of unrealistic beauty standards and view sculpted bodies as unnatural.
Researchers at UC Riverside discovered that stacking three layers of graphene creates a 'knob' for tuning its electrical properties. The team found that some trilayer graphene devices were conducting while others were insulating, depending on the layer order.
The primary structure of NASA's Mars Atmosphere and Volatile Evolution (MAVEN) mission has been completed, marking a significant milestone in the project. The spacecraft will undergo static load testing before propulsion subsystem integration begins.
Research at the University of Texas MD Anderson Cancer Center found that couples counseling significantly improves sexual satisfaction and function for prostate cancer survivors and their partners. Internet-based sexual counseling was shown to be equally effective as traditional sex therapy.
A new study found that underweight COPD patients are 1.7-times more likely to die than those with a normal body weight. Additionally, heart disease and cardiac failure increase mortality rates among COPD patients.
A large study found that high blood pressure is associated with a higher risk of developing cancer and dying from the disease, particularly in men. The study analyzed data on blood pressure and cancer incidence and death in over 289,000 participants.
A large study led by Stanford urologist Michael Eisenberg found that childless men are more likely to die from cardiovascular disease than fathers. The study tracked over 135,000 male members and found a 17% increase in mortality risk among childless men compared to fathers.
A randomized trial found that a shorter radiation course for prostate cancer with hypofractionation is as effective as conventional radiation therapy at five years after treatment. The study used intensity modulated radiotherapy (IMRT) to limit dose to normal tissues, reducing side effects.
A study of over 1,100 women found hip fractures increase short-term mortality rates for women aged 65-79 and those aged 80+, even after controlling for underlying health status. Healthy women in this age group are at increased risk of death after a hip fracture.
Research found that drug company stock prices increased by 13.7% before positive phase III clinical trials and decreased by 0.7% before negative trials. The study also showed that stock prices of established companies with positive trial results were more likely to increase than those of smaller companies with negative trial results.
Researchers at Rhode Island Hospital discovered a potential link between non-steroidal anti-inflammatory drug (NSAID) use and cardiovascular complications in animal models with hypercholesterolemia. The study suggests that controlling cholesterol may be crucial for heart health in patients taking NSAIDs.
Scientists discovered that Denisova hominins interbred with modern humans at least 44,000 years ago, contributing genetic material to populations in Southeast Asia and Oceania. The study suggests that there were at least two migration waves, contradicting previous assumptions about human settlement in the region.
A study found that children born after mothers received chemotherapy during pregnancy had normal cognitive and cardiac development, but those born preterm were more likely to experience developmental delays. Researchers recommend continuing cancer treatment during pregnancy unless preterm delivery can be prevented.
Researchers have found that treating mice with oculocutaneous albinism caused by mutations in the Tyr gene resulted in improved eye and hair pigmentation when treated with nitisinone. This suggests a potential new treatment for a subset of patients with OCA1B, a form of albinism associated with vision loss.
A new study reveals that people with COPD are at a high risk of developing cardiovascular disease, highlighting the need for routine screening. The study found that 50.1% of patients with COPD had cardiovascular conditions, compared to 41% of those without COPD, emphasizing the importance of identifying comorbidities in clinical practice.
A new study from CSIRO Australia has found that Australia's average wind speed is increasing, contrary to recent international studies showing a decrease. The research provides valuable insights into the causes of variations in near-surface wind and long-term wind speed trends over Australia.
Researchers have developed a technique to create low-cost, high-performance copper nanowire films for displays and solar cells. The new copper nanowire films outperform current indium tin oxide (ITO) films, which are highly transparent but expensive and prone to cracking.
Tropical Depression Haitang is expected to make landfall near Hue, Vietnam tomorrow. Satellite imagery reveals cloud-top temperatures exceeding -63F, indicating strong thunderstorms and heavy rainfall ahead.
A recent study by Kaiser Permanente found that women aged 65-69 who break a hip are five times more likely to die within a year than those who don't. The study also discovered that for women aged 70-79, a hip fracture doubles the risk of dying, while for those aged 80 and older in excellent health, it nearly triples. These findings hig...
The UNC Center for Diabetes Translation Research to Reduce Health Disparities aims to reduce diabetes-related disparities among poor and underserved populations. The center will leverage existing resources at NC TraCS Institute and partner with several universities and health departments to foster translational research.