Researchers at Harvard's Wyss Institute have developed a DNA nanorobot that can seek out specific cell targets and deliver molecular instructions to cause cancer cells to self-destruct. The technology uses modular components to mimic the body's immune system and has the potential to treat various diseases.
A $10.5 million grant will enhance the CPALMS system, a free online platform that guides teachers to teaching tools and resources, with new features including learning progression maps and messaging tools. The improved system will better support standards-driven instruction in mathematics, science, and reading/language arts.
A new study found that patient education classes can improve access to kidney transplant evaluations for blacks and patients living in poor neighborhoods. After implementing a required educational session, 80.4% of patients completed an evaluation within one year, compared to 44.7% before the program.
The Collaborative Cross project in North Carolina has created a vast library of genetic material, mirroring human diversity in mice. This enables faster and more accurate understanding of genetic variation's impact on living systems, potentially leading to breakthroughs in treatment and prevention for human diseases.
A new study by Wayne State University reveals that an autoinjector delivering midazolam can effectively stop prolonged seizures in patients, with 73% of participants seizure-free upon hospital arrival. This method is faster and more reliable than traditional intravenous treatment.
A new clinical trial shows that high doses of 'load' through programmed electrical stimulation of the muscle significantly slows bone density loss in patients with spinal cord injury. Average bone density in the femur was almost 40% lower in patients who received low or no load compared to those who received high load.
A group of over 150 paediatricians warn that the UK Government's proposed reforms will lead to increased fragmentation in care, harming vulnerable children and families. The bill is expected to limit choice and increase inequalities in healthcare outcomes.
A study by Wayne State University School of Medicine researchers found that targeted tumor freezing therapy increases ovarian cancer survival rates, with a 56-month average survival rate reported in 98% of patients. The treatment, called cryoablation, has been shown to be cost-effective, saving an average of $26,806 per life year.
A new study shows that an implantable microchip can deliver medication on command, improving bone formation and reducing the risk of bone fracture in women with osteoporosis. The device, which is roughly the size of a pacemaker, releases medication via a wireless signal and has shown to be effective and safer than traditional injections.
Researchers have developed a new and effective way to regrow blood vessels, potentially bypassing surgery and repairing damaged vessels through injection of a lipid-incased substance. This method has shown promise in treating chronic myocardial ischemia disease, affecting up to 27 million patients in the US.
A recent study by WALTHAM Centre for Pet Nutrition and University of Liverpool found that pregnant women who own dogs are approximately 50% more likely to meet the recommended daily physical activity level. This research highlights the potential benefits of dog walking as a low-risk exercise strategy for managing weight gain during pre...
Researchers use aerial measurements from Washington State's Channeled Scablands to analyze Mars' jointed basalt columns, offering insights into the Red Planet's volcanic history. By studying the cracks and widths of these columns, scientists can infer the cooling rate of basalt on Mars.
Researchers developed a predictive model that differentiates between dengue fever and its deadly form, dengue hemorrhagic fever (DHF), using protein biomarkers. The model is based on IL-10 and seven distinct proteins, accurately predicting DHF in 100% of cases.
A team of scientists led by Bing Ren has discovered how differential DNA methylation in the parental genomes sets the stage for selective expression of imprinted genes. The study found parent-of-origin specific DNA methylation imprints at 1,952 dinucleotide sequences, including previously unknown regions.
Researchers at Polytechnique Montréal developed a new transfection method that changes the genetic material of cancer cells, allowing for precise nanometric-scale surgery. This breakthrough could lead to new therapeutic approaches in oncology, neurology, and cardiology, with promising applications.
A study by University of Chicago researchers found that puzzle play between ages 2 and 4 is a significant predictor of spatial skill in preschoolers. Children who played with puzzles had better spatial skills than those who did not, on tasks that assessed their ability to rotate and translate shapes.
A new MIT system allows robots to build and update 3D maps of their surroundings using a low-cost camera, enabling navigation in constantly changing environments without human input. The system can be used for applications such as blind navigation, military mapping, and HazMat team operations.
Sandia's decontamination foam is now used to clean up illegal methamphetamine labs, leaving chemicals harmless and surfaces safe for reuse. The foam contains mild, non-toxic chemicals that break down agent molecules into nontoxic pieces.
Researchers found that soldiers experiencing depression and/or PTSD during or after deployment were most likely to develop new onset alcohol abuse. The study suggests that self-medication with alcohol may be a coping mechanism for these individuals.
Researchers sequenced the complete genome of an immortal Tasmanian devil and its transmissible cancer, providing insights into how the disease spread rapidly through the population. The study identified over 17,000 mutations in the cancer genome, which may lead to therapeutic strategies against cancer genes.
The Goddard Institute for Space Studies will receive specialized scientific support services from Trinnovim, LLC, under a $2.86 million contract. The services include scientific programming, analysis, and logistical support for GISS research programs.
A UC Riverside researcher has received a $385,000 grant to evaluate the efficiency of HVAC motors in buildings through on-site testing and a new motor testing facility. The study aims to measure energy use under actual operating conditions and assess software used by architects and engineers designing HVAC systems.
The new report updates the landmark STRAW system, providing a clearer understanding of reproductive aging in women from pre-menopause to the late postmenopausal period. The updated stages include significant revisions, offering more precise definitions and predictions for the onset of menopause.
Researchers have found a new type of defect in quasicrystals that extends beyond the surface and into the bulk. This discovery sheds light on the relationship between surface and bulk defects in materials, which is crucial for understanding the strength and properties of nanostructures.
A new study by RAND Corporation concludes that eliminating the individual mandate under the Affordable Care Act would sharply decrease health coverage, but not dramatically hike insurance prices. The number of Americans predicted to get coverage in 2016 would drop from 27 million to 15 million if the individual mandate were eliminated.
A recent study by Emory University found that fruit flies infected with blood-borne parasites consume alcohol to increase their survival rate. The researchers discovered that the toxic effects of alcohol can be protective against infectious disease and raise an important question about whether other organisms, including humans, could c...
Researchers analyzed six RNA binding proteins that control genetic splicing, discovering they work together to regulate thousands of genes. The study highlights the importance of these proteins in maintaining cell homeostasis and may offer clues for rational drug design.
A new strategy combining carbon nanoparticles with chemotherapy and radiation therapy shows significant potential in treating head-and-neck cancers. The treatment uses nanoparticles to encapsulate chemotherapeutic drugs, delivering them directly to cancer cells.
Researchers at Wake Forest University used video game graphics processing units (GPUs) to simulate human cell behavior, revealing new insights into the telomerase enzyme and its role in cancer. The study's findings could lead to the development of new cancer treatments by targeting the enzyme.
Research found that stroke patients experienced persistent eating difficulties and remained at nutritional risk three months after their stroke. Despite improvements in physical functions, most patients' eating abilities remained unchanged or deteriorated.
Researchers at MGH Cancer Center have discovered a potential treatment target for KRAS-mutant colon cancer, which may lead to new strategies for treatment-resistant tumors. Targeting TAK1 and BMP pathways may induce tumor cell death, offering hope for patients with KRAS-dependent colon cancers.
The study validated the use of a microchip-based device to deliver teriparatide for osteoporosis treatment, with results comparable to standard injections. The implant showed biocompatibility and was well-tolerated by patients, providing proof-of-concept for long-term device viability.
Researchers have developed a new catalogue of loss-of-function (LoF) variants to better understand the normal function of human genes. The study identifies over 1000 LoF variants, some of which are rare and potentially harmful, while others may not have a significant effect on health.
A new study has mapped the genome of a Quarter Horse mare using next-generation sequencing, revealing genetic variants associated with sensory perception, signal transduction, and immunity. The research found that Quarter Horses have more genetic variation than Thoroughbreds, particularly in genes involved in these traits.
A Yale University study has assessed the criticality of metals in the geological copper family, finding arsenic as the most vulnerable to long-term supply disruption. The research methodology evaluates supply risk, environmental implications, and vulnerability to supply restriction, highlighting the importance of considering these fact...
Researchers at Queen's University have developed a soft tissue replacement technology using discarded human fat, showing promise in promoting natural soft tissue regeneration. The technology can be used to repair or replace damaged or missing soft tissue caused by various injuries or surgeries.
Researchers at OHSU discovered glial cells, previously thought to support growth, actually regulate the growth of brainstem neurons responsible for cardiorespiratory control. This finding has profound implications for the prevention and treatment of SIDS, with potential applications in high blood pressure and other disorders.
Changes in ocean conditions and species shifts over the past 50 years suggest that static MPAs may not work as intended. New technological advances and collaboration will be necessary to design effective MPAs in a changing climate. Researchers are calling for greater foresight and flexibility in MPA management.
Researchers from University of Wisconsin-Madison find that nacre's microscopic structure can be used to measure water temperature and depth, providing a new tool for reconstructing ancient environments. The material's unique signature also holds information on environmental conditions.
A new study from Rensselaer Polytechnic Institute shows that men and women faculty are retained at the same rate, except in mathematics departments where women depart sooner. The median retention rate for all university professors is just 11 years, highlighting a significant challenge for universities.
Researchers at the University of Minnesota discovered that cell phone networks leak user locations, allowing hackers to track their movements. The team used inexpensive phones and open source software to demonstrate the vulnerability on the GSM network.
Researchers fortify soft goat cheese with fish oil to increase omega-3 fatty acid content and balance proportions. The addition of dairy helps protect fish oil from oxidation, making it a viable option for healthy food choices.
A study published in the Clinical Journal of the American Society Nephrology found that adding information on how to treat chronic kidney disease (CKD) patients to kidney test results did not improve care. The study included 22,092 patients with CKD and found no difference in the use of recommended medications between those who receive...
A study by researchers at the University of Chicago found that puzzle play in children aged 2-4 years significantly improves their spatial skills, which are essential for mathematics, science, and technology. Higher income parents who engaged their children in puzzle play more frequently showed a greater impact on spatial skills develo...
The team's proof-of-concept motor utilizes carbon-based switches to activate artificial muscles, which then rotate a shaft without external electronics or hard metal parts. The device has the potential to open doors for softer, lighter electrostatic motors with applications in prosthetics and soft robots.
Researchers report growing success in combining therapeutic cancer vaccines with conventional chemotherapy, stimulating the immune system to destroy cancer cells. The first FDA-approved cancer vaccine is for metastatic prostate cancer, and several other strategies are being tested for various types of cancer.
A new UCLA study found that a widely used assessment tool for community health centers may not accurately measure the quality of diabetes care. The study examined 30 Los Angeles County health centers and found no correlation between the tool's scores and the actual quality of care.
Salk researchers have identified a new potential drug target for treating certain types of lung cancer. By blocking the activity of the enzyme IKK2, which regulates inflammation, the study found that tumors grew more slowly and animals lived longer.
A new computational method has been developed to analyze RNA motifs, revealing new structural patterns that can help understand the role of RNA in cellular function. This breakthrough may lead to new treatments for certain diseases, according to researchers at the University of Central Florida.
Cyclone Giovanna has caused flooding and damage in Madagascar before entering the Mozambique Channel. The storm is expected to move westward towards Mozambique's southeastern coast, with wind shear preventing further strengthening.
A new species of tiny, black and orange grasshopper-like insect has been found in the Toledo District of southern Belize. The insect, Ripipteryx mopana, is only 5mm long and uses its large jumping hind legs to escape predators.
A national trial has shown that autoinjectors are quicker and more effective in stopping seizures than traditional IV line treatment. The study found that patients who received midazolam via an autoinjector were 73% seizure-free upon arrival at the hospital, compared to 63% of those receiving IV lorazepam.
A recent study found that female cancer survivors have poorer health behaviors than women without a cancer history, including higher rates of smoking and weight gain. Researchers hope to capitalize on these 'teachable moments' to encourage healthier lifestyles among cancer survivors.
A symposium on disaster recovery will focus on the importance of community preparation and collaboration in overcoming emergency hardships. The event aims to provide insights into strategies for resilience and faster recovery times.
Lung cancer patients face geographic challenges to access clinical trials due to molecular preselection. Researchers propose using online patient communities and innovative trial approaches to inform patients about trials, accelerate research, and address practical challenges in conducting personalized medicine trials.
A recent study of 56 children with autism spectrum disorders found no statistically significant correlation between urinary mercury levels and autism. The researchers suggest that mercury excretion rates are unlikely to have a clear causal link to autism spectrum disorders.
A nationwide study has shown that injecting anticonvulsant medication into the thigh muscle using an autoinjector is as safe and more effective than traditional intravenous administration. The method resulted in 73% of patients being seizure-free upon arrival at the hospital, compared to 63% for those receiving IV treatment.
Research found that middle-aged individuals with slower walking speed are one-and-a-half times more likely to develop dementia, while those with weaker hand grip strength are at a higher risk of stroke. Conversely, faster walkers and stronger grippers have lower risks, according to the study.
Hospitalizations for US underage drinkers are common, with an estimated 700,000 young people hospitalized in 2008. The majority were drunk upon arrival, and the average age of those with alcohol-related discharges was 18 years old.
The US Energy Department has granted over $1.8 million to a researcher studying terpenoids in plants as a potential fuel source. The goal is to create a sustainable fuel production method that can be easily extracted from plants, reducing dependence on oil fields.