Articles tagged with Myocardial Infarction
A new study by Dr. Todd Anderson at the University of Calgary's Libin Cardiovascular Institute has identified endothelial dysfunction as a predictive marker for coronary heart disease. By detecting this marker in patients, doctors may be able to intervene early to prevent the progression of heart disease.
Elderly black patients are more likely to be readmitted to the hospital after a prior hospital stay for heart attack, heart failure, or pneumonia. The study found that racial disparities in health care and hospital care contribute to higher readmission rates among black patients.
A study by researchers at UCLA Stroke Center found that strokes and cardiovascular disease exacted an enormous toll on Hollywood stars. The team identified 30 actors who suffered strokes and 39 heart attacks among Oscar nominees between 1927 and 2009, with women accounting for 60% of stroke victims.
Research from University of Warwick reveals prolonged sleep deprivation increases risk of strokes, heart attacks, and cardiovascular disorders, highlighting importance of getting 7 hours of sleep per night.
New nanoparticles designed to target fibrin in blood clots can be seen with a new type of CT scanner, providing early detection and potential treatment options for heart attacks. This technology has the potential to save lives by quickly identifying unstable plaque and guiding targeted treatments.
A new study found that hospital spending is associated with lower death rates for patients with life-threatening conditions, including heart attacks, strokes, and pneumonia. High-spending hospitals had a 19% lower mortality rate compared to low-spending hospitals.
Researchers have found that RevaTen platelet-rich plasma stimulates cell repair via growth factor release, attracting reparative cells. Studies indicate significant improvements in cardiac function and reductions in scar tissue after treatment with RevaTen PRP.
A new study identifies genetic variants associated with coronary artery disease (CAD) and heart attacks. The researchers found that certain genetic profiles increase the risk of CAD and heart attacks in individuals with CAD, while blood group O offers protection against heart attacks.
Cardiologists at UConn Health Center have identified a protein fragment that can predict heart attack, allowing for earlier diagnosis and potentially life-saving treatment. The discovery could also lead to the development of new therapies to block cell death and preserve heart muscle function.
Researchers found Longevinex, a resveratrol supplement, provides cardio-protection across a wide dosage range without toxic effects. Unlike plain resveratrol, Longevinex exhibits an L-shaped safety curve, minimizing heart damage and optimizing protection.
A recent study published in PLoS ONE found that Longevinex exerts a greater influence on genes than resveratrol, leading to improved heart health outcomes. The research demonstrated that Longevinex reduced the size of heart attacks and protected against cell death, while also improving microRNA activity.
A new study found that cardiac troponin T levels detected with a highly sensitive assay are associated with structural heart disease, cardiovascular mortality, and increased all-cause death in the general population. The prevalence of detectable cTnT varied by sex, race, age, and comorbidities.
A University of Cincinnati study reveals that helicopter emergency medical services can delay treatment for STEMI heart attack patients. The study found that only a few patients received treatment within the recommended 30-minute goal, highlighting the need for streamlined systems to reduce transfer times.
A new blood test can detect cardiac troponin T levels in 25% of seemingly healthy individuals, indicating an increased risk of dying from heart disease. The test's results showed that those with elevated troponin T levels were nearly seven times more likely to die within six years.
A large-scale study found that patients with rheumatoid arthritis have a 60% higher risk of heart attack just one year after diagnosis, with the risk increasing rapidly in the first few years. The study emphasizes the importance of monitoring heart risk from the moment RA is diagnosed.
Researchers found that common genetic variants near aging-related genes influence the production of circular RNAs, which control INK4/ARF gene expression and risk of diseases like heart attack and stroke. Individuals with more of these circular forms have increased INK4/ARF gene expression.
A new study published in Sleep reveals that myocardial infarction can cause paradoxical sleep phase disruption and reduced cholinergic neurons, leading to insomnia. The research highlights the critical role of rapid treatment and preventive measures to mitigate post-infarction complications.
Research found that women who experienced recurrent miscarriage were five times more likely to have a heart attack in later life. Those who had stillbirths were also at increased risk of cardiovascular disease.
Researchers found increased vascular reactivity and decreased endothelial function in women with broken heart syndrome compared to postmenopausal women and those who had regular heart attacks. This unique risk factor highlights the importance of mental stress in ABS syndrome, which may lead to the development of specific therapies.
Researchers from Leicester and Cambridge discovered genetic markers that identify people at risk of developing potentially fatal blood clots. This breakthrough advances ways of detecting and treating coronary heart disease, a leading cause of premature death.
Researchers at Duke University Medical Center discovered a stem cell secreted protein that improves heart muscle repair after a heart attack. The protein, sfrp2, reduces collagen layering and prevents heart failure in study rats.
Researchers tested genetic variations in 1,262 people with no history of heart disease and found that genetic scores can modify the estimated risk of heart attack. The study suggests that genetic screening may be most valuable for individuals thought to be at intermediate risk using current models.
A new study suggests that fat-derived stem cells can safely improve heart function after a heart attack by reducing damaged tissue, increasing blood flow, and boosting the heart's pumping ability. The treatment was found to be effective in patients with severe heart attacks, but further research is needed to confirm its efficacy.
A Johns Hopkins study of 950 healthy men and women found that nearly 95% of heart attacks, strokes, or heart-related deaths occurred in those with measurable artery-hardening calcium buildup; healthy individuals without calcification had minimal coronary protection. Statin therapy should only be considered for those at greatest risk.
Researchers at the University of Cincinnati have identified a protein called HAX-1 that protects cardiac cells and muscle from damage during ischemia-reperfusion injury. The study found that HAX-1 levels were reduced in hearts after heart attack, but overproduction improved contractile performance and decreased cell death.
Researchers found that injecting a platelet inhibitor directly into the heart through a coronary artery may restore blood flow more effectively than conventional administration after a severe heart attack. In contrast, erythropoietin did not reduce heart damage but may increase it in patients over 70 years old. Additionally, measuring ...
Researchers at Mayo Clinic have shown that iron buildup is prevalent in unstable coronary artery plaque, making it a potential marker for risk of myocardial infarction and sudden death. Non-invasive imaging techniques, such as micro-CT scans, may soon be able to detect these plaques, allowing for earlier intervention.
Despite a high frequency of cardiac risk factors, many patients presenting with acute heart attacks are not on primary prevention medications. The study found that nearly 400,000 patients present annually with ST-elevated myocardial infarction (STEMI) in the US, highlighting the need for improved preventive care.
Researchers at the University of Cincinnati have developed a stem cell-infused patch that promotes cell migration to damaged cardiac tissue following a heart attack, resulting in improved function. The patch combines cardiomyocytes, endothelial cells, and embryonic fibroblasts to enhance regeneration of heart tissues.
Recently bereaved individuals experience elevated heart rates and potentially harmful heart rhythm changes, increasing the risk of heart attack and sudden cardiac death. These effects tend to normalize within six months.
A study presented at the American Heart Association's Scientific Sessions found that light to moderate drinking among male coronary artery bypass patients was associated with 25% fewer subsequent cardiovascular procedures and death compared to non-drinkers. However, heavy drinkers were twice as likely to have subsequent cardiovascular ...
Research found that women with high job strain have a 40% increased risk of cardiovascular disease, including heart attacks and the need for procedures to open blocked arteries. Job insecurity was also associated with risk factors for cardiovascular disease such as high blood pressure, increased cholesterol, and excess body weight.
A computer-automated monitoring system identified a drug-releasing stent with significantly higher rates of major adverse cardiac events compared to similar stents. The study found that automated surveillance of clinical registries can efficiently identify emerging postmarket safety risks.
A recent study found that patients with non-STEMI heart attacks often experience long delays to hospital arrival, with a median delay time of 2.6 hours. Despite efforts to improve timely care, many patients still wait over two hours before seeking medical attention.
A study published in Archives of Internal Medicine found that door-to-balloon time has dropped dramatically for heart attack patients, from 113 minutes in 2003 to 76 minutes in 2008. However, despite the quicker hospital care, mortality rates remained unchanged at around 4%.
A review published in the Canadian Journal of Cardiology finds that consuming egg yolks can significantly increase cardiovascular risk for patients at risk of vascular disease. The researchers advise limiting dietary cholesterol to less than 200mg per day and recommend alternative protein sources like egg whites.
A study of nearly 2,000 patients who had been treated for a heart attack found that many were not receiving the correct dose of beta blockers. The majority of patients were taking less than 50% of the target dose, which can lead to increased risk of subsequent heart attacks.
A recent study found that newer treatments for age-related macular degeneration, including intravitreous bevacizumab and ranibizumab, do not significantly increase the risk of cardiovascular complications or death. The study analyzed data from 146,942 Medicare beneficiaries treated for AMD in 2005 or 2006.
A team of researchers at the University of Pennsylvania School Medicine discovered a three-way control mechanism for fetal heart cell proliferation. This finding could help cardiologists understand the natural repair process after heart attacks and develop new therapies to expand cardiac stem cells.
A recent study led by St. Michael's nephrologist Dr. Ramesh Prasad has found that South Asian patients are more than twice as likely to suffer a heart attack after a kidney transplant compared to Caucasian, black and East Asian men and women.
Researchers found that inhibiting GRK2 protects heart cells from destruction after a heart attack, while excess GRK2 leads to more damage. The discovery suggests that anti-GRK2 gene therapy may help prevent permanent heart damage.
A US clinical trial demonstrated the strong safety profile of bone marrow-derived mononuclear cells in patients after a severe heart attack. The study found improvements in left ventricular ejection fraction and volumes at six months, suggesting potential benefits for cell therapy trials.
New findings from a major drug trial have revealed that the platelet function in patients taking ticagrelor recovered much quicker after the drug is stopped, compared to clopidogrel. Additionally, ticagrelor has been shown to prevent 1 in 5 deaths after a heart attack, even in patients with adverse effects like breathlessness.
Researchers at the University of Western Ontario have discovered a link between chronic stress and heart attacks using hair cortisol levels as a biological marker. The study found that heart attack patients had higher cortisol levels in their hair samples compared to control group, suggesting chronic stress as a contributing factor.
Researchers at UT Health Science Center San Antonio will study protein fragments released into the bloodstream following heart attacks to identify those who need more intensive treatment. The goal is to develop a blood test to diagnose which heart attack survivors are at risk of heart failure.
A study of 45,227 patients with atherothrombosis found that hypertension, hypercholesterolemia, and diabetes increased the risk of future cardiovascular events. Polyvascular disease was also identified as a strong risk factor for ischemic events.
A new study in mice shows that social support can minimize physical damages to the brain caused by a heart attack. Socially isolated mice suffered more cell death, depressive symptoms, and inflammation than those living with a partner.
A new study published by the American Heart Association compares the risks of diabetes drugs rosiglitazone and pioglitazone, finding that patients taking either medication have a similar risk of heart attack, heart failure, or death. The study included over 36,000 patients and followed them for 33 months.
High-risk patients undergoing coronary procedures with elective IABP insertion did not experience improved rates of events or death. The study found more minor bleeding in the IABP group, but no significant difference in major bleeding or MACCE.
A study found that long-term cumulative mortality was highest among patients with system delays of 121-180 minutes, increasing by 28.1% and 30.8% respectively. System delay was independently associated with mortality in multivariate analysis.
Researchers implanted genetically engineered stem cells with cytokines HGF, SDF-1, and VEGF to reduce organ damage and improve cardiac function after a heart attack. The results showed that two therapies - SDF-1 and Akt1 overproduction - limited cardiac damage.
A study published by the American Psychological Association found that people with insecure attachments in relationships may be at higher risk for cardiovascular problems. Those with anxious attachments were particularly associated with a range of health conditions, including chronic pain and cardiovascular diseases. The researchers al...
Sepsis and septic shock are common complications in general surgery patients, with a death rate of approximately 34% within 30 days. The study identified risk factors for sepsis and septic shock, including age, emergency surgery, and co-occurring illness.
The Cedars-Sinai Heart Institute has received a $1.66 million grant to develop a measurement system predicting patient vulnerability to sudden cardiac arrest. The study aims to identify patients at high risk of sudden cardiac arrest by analyzing electrocardiogram data.
A recent analysis of a large clinical trial found no increased rate of heart attack or death in patients taking rosiglitazone, despite previous concerns. The study compared patients treated with rosiglitazone to those not receiving any thiazolidinedione drug, showing a lower combined rate of death, heart attack, and stroke.
A new meta-analysis of clinical trials finds that rosiglitazone is associated with a significantly increased risk of myocardial infarction, while the risk of cardiovascular death was not elevated. The study suggests an unfavorable benefit-to-risk ratio for the diabetes drug, raising concerns about its safety.
A study of 12,064 survivors of heart attack found that folic acid and vitamin B12 supplementation did not lower the risk of heart attack, coronary death, or stroke. The researchers also found that folic acid supplementation did not increase the risk of cancer.
A team of bioengineers from the University of Pennsylvania Institute for Medicine and Engineering developed a simulator to predict how blood platelets respond to various conditions during a heart attack or stroke. The model accurately predicted intracellular calcium signaling responses, even distinguishing between different donors.
The INTERSTROKE study found that high blood pressure, smoking, waist-to-hip ratio, diet, physical activity, lipids, diabetes mellitus, alcohol intake, stress, and depression are significantly associated with stroke. Collectively, these risk factors accounted for 90% of the global risk of stroke.
Researchers found that monocyte-derived cells can induce myocardial protection by reducing cardiac cell apoptosis and enhancing endothelial cell proliferation. The cells also secrete growth factors with anti-inflammatory properties, which help protect heart tissues from programmed cell death.