New phosphate-free automatic dishwashing detergents are being developed to combat water pollution, but they may not be as effective as previously thought. Researchers are working on alternative formulas that can clean dishes without contributing to environmental harm.
Researchers are calling for a shift in focus towards prevention, but current therapies targeting brain plaques may be less effective in patients already experiencing symptoms. Developing biomarkers to identify pre-symptomatic volunteers could help test Alzheimer's drugs more effectively.
Advances in recording technology and data analysis are set to revolutionize brain research, enabling better understanding of the brain's functional principles. Researchers at RIC have found that the number of simultaneously recorded single neurons has grown exponentially since the 1950s, doubling approximately every seven years.
Mount Sinai researchers have identified insulin-like growth factor II (IGF-II) as a potential therapeutic target for enhancing long-term memory and preventing its loss. IGF-II, a gene expressed during brain development that declines with aging, was found to improve long-term memory in rats by promoting stable LTP.
The Air Force Office of Scientific Research has selected winners for the Nanosat-6 Flight Competition Review, with Michigan Technological University taking first place. The winning teams will receive assistance to become flight-ready, and one satellite will be launched as a secondary payload on an STP launch.
Researchers demonstrate the role of cellular bioenergetics in selectively inhibiting pathogenic lymphocytes while preserving normal immune function. Lycera's prototype compound Bz-423 induces selective apoptosis of alloreactive donor T cells, reversing graft-versus-host disease and improving survival in mice.
A new study reveals that female striped plateau lizards' colorful patches during reproduction season boost yolk antioxidants in their eggs, resulting in healthier offspring. The research suggests that females with more vibrant coloration may be more attractive to males and produce higher-quality offspring.
A study published in the Journal of Management Studies found that dominant CEOs can drive companies to extremes of performance. However, a strong board of directors can mitigate this effect and improve company performance. Companies with powerful boards tend to have better outcomes than those without them.
Scientists successfully applied home device technology to increase solubility of anticancer drugs like tamoxifen and paclitaxel. The process has potential for improving performance of dyes, paints, rust-proofing agents and other products.
Researchers have identified a key molecular mechanism in nerve fibers that ensures rapid conductance of nervous system impulses. The myelin sheath, which acts as an insulating membrane, allows electrical impulses to hop from one node to the next along the axon.
A Tel Aviv University researcher has found that fibroblasts, a type of connective tissue cell, can be coerced into supporting inflammation and tumor growth. This discovery opens new avenues for drug research and may help manage inflammation to reduce cancer growth.
A new study reveals that a subspecies of grey wolf, previously thought to be a golden jackal, is actually a distinct species found in Africa. Genetic evidence confirms that the Egyptian jackal belongs to the grey wolf species complex.
A study by University of Illinois Chicago researchers found that certain strains of Listeria monocytogenes can invade the heart, leading to serious and difficult-to-treat cardiac infections. The bacteria display modified proteins that enable easier entry into cardiac cells, making them a new target for treatment.
Two Agave species have yielded significantly more than other biofuel crops in independent studies, making them a promising alternative for global energy needs. The crop's potential to thrive in semi-arid regions without significant land demands offers a sustainable and environmentally-friendly production method.
A study by Purdue University found that diabetes affects not only patients but also their spouses, causing similar distress and depressive symptoms. The research highlights the importance of considering the emotional impact on both individuals in diabetes care.
Researchers at Georgia Tech have developed a new treatment system that uses magnetic nanoparticles to capture free-floating cancer cells, slowing tumor progression in humans. The system aims to reduce chemotherapy side effects by removing the primary source of metastasis.
A groundbreaking study led by LSU's Mark Batzer has decoded the orangutan genome, revealing unexpected insights into its evolution and genetic diversity. The research found that two distinct orangutan species exist, with one species having limited genetic diversity due to a condensed habitat.
Research focuses on magnetism in three new classes of materials, including strange iridium oxide-based metals and topological insulators. The study aims to understand spin-orbit coupling effects in these materials for future energy transport and computing applications.
Stefan Jentsch receives prize for discovery of ubiquitin's role in genome maintenance and DNA repair, while Edvard and May-Britt Moser win for grid cells discovery that enables spatial navigation and memory.
Researchers have found that rt-PA can help prevent both catheter malfunction and blood stream infections in hemodialysis patients. The study, published in the New England Journal of Medicine, showed a significant reduction in complications among patients who received rt-PA.
Researchers found that three signaling pathways work together to regulate plant pollen production, with two being sufficient for optimal fertility. The study sheds light on the complex interactions between genes and environmental conditions that influence flower formation and reproductive success.
A new quality improvement program for pediatric surgery has shown promise in identifying reasons for complications and implementing improvements to reduce mortality rates and post-operative complications. The program, based on the American College of Surgeons National Surgical Quality Improvement Program, uses data to target specific p...
Researchers warn of potential health dangers from mixing energy drinks with alcohol, citing concerns over caffeine intake and increased risk of alcohol-related consequences. Experts advocate for regulatory changes, education, and manufacturer warnings to mitigate these risks.
By adding subsoil information to a sedimentation and erosion model, researchers at Delft University of Technology gained a clearer picture of how rivers and deltas develop over time. This new understanding can help with delta management and reservoir geology, particularly in finding oil reserves.
A new study by WWF scientists finds that tiger reserves in Asia can support over 10,000 wild tigers if managed as large-scale landscapes. The researchers believe that protecting core breeding sites and developing forest corridors can ensure tiger population growth.
Researchers at the University of Calgary have made a breakthrough discovery about how calcium channels regulate neuronal activity. The study reveals that a protein called beta subunit acts as a molecular switch to stabilize or remove calcium channels, controlling excitability in nerve cells.
A study using a 'fingerprinting' technique has identified the main sources of mercury in Bay Area fish, tracing it back to sediments and historic mining sites. The findings suggest that small fish acquire mercury from sediments and pass it along to larger fish, highlighting the need for targeted efforts to protect wildlife.
Researchers at the University of Arizona have created a sophisticated experimental setup to measure the interactions between single atoms and surfaces. The technique refines our understanding of the van-der-Waals force, which is crucial for chemistry, biology, and physics.
Researchers analyzed data on 45,000 CABG patients and found a decline in stroke occurrence over the past three decades. The study identified various risk factors associated with stroke after CABG, including older age, previous stroke, and certain surgical techniques.
Researchers found that the nematode C. elegans, a millimeter-long worm used extensively for decades to study biology, gets naturally occurring viral infections. The discovery means C. elegans is likely to help scientists study the way viruses and their hosts interact.
Hospitals with designated stroke centers in New York State have a significantly higher survival rate for patients with ischemic stroke, with a 15-20% increased likelihood of survival. Patients treated at these centers are also more likely to receive acute stroke therapy.
Physicists in Iran have created a spintronic device based on armchair graphene nanoribbons, which could revolutionize handheld electronics and drastically reduce manufacturing costs. The device has been shown to be an effective spin switch, with properties useful for magnetic random access memory.
Researchers have discovered a new method to fight bacterial infections associated with contact lenses, breaking apart molecular scaffolding that encases bacteria and reducing infection rates by 79.2%. The treatment has promising early results for treating microbial keratitis, cystic fibrosis, and severe burns.
Researchers found that N-acetylcysteine reduces the size and activity of von Willebrand factor multimers in human plasma and mice, offering a potential rapid treatment for patients with TTP. The study suggests that this approach could be effective in reducing complications associated with current treatments.
New materials could enable ultrapowerful microscopes, improved solar cells, and a possible cloak of invisibility. The breakthrough is made possible by overcoming two major limitations in metamaterials development: light absorption and precision tuning.
Researchers combined two proteins and a stress response protein to create a new TB vaccine strategy that provided stronger, more long-lasting protection than the current BCG vaccine. The study found that this multistage vaccine controlled reactivation of latent infection and reduced Mtb levels in the lungs more effectively.
The development of core outcome sets for clinical trials requires patient input to ensure relevant outcomes are measured. The study emphasizes the importance of involving patients and clinicians in the process, while minimizing participant attrition.
The study found that an area of the brain responsible for holding abstract working memory can also hold auditory information. This discovery may help scientists better understand and treat conditions such as learning disabilities, autism, and schizophrenia.
A study by Ben-Gurion University researchers found that workers with occupational-related hearing loss experienced impaired sleep quality, including insomnia and excessive daytime sleepiness. The study also discovered a significant correlation between tinnitus symptoms and sleep disruptions in workers exposed to harmful noise.
A study published in World Journal of Gastroenterology found that hemolysis leads to decreased intestinal microcirculatory blood flow, causing intestinal damage. Elevated circulating cell-free oxyhemoglobin levels resulted in a strong correlation with intestinal injury.
Scientists have made a breakthrough in developing a vaccine to protect against plague and bacterial pneumonias. The new discovery involves the stimulation of Th1-17 cells, which provide partial protection against pneumonic plague.
The American Society for Radiation Oncology's new journal, Practical Radiation Oncology (PRO), has published its inaugural issue. PRO will provide a forum for radiation oncologists to share information on current practices and advancements in the field. The journal aims to improve the quality of radiation oncology practice through disc...
Scientists developed a mathematical model to describe interactions within ecological food webs, illustrating how human intervention can aid species conservation. The study found that over 70% of extinctions are preventable by balancing the system with available resources.
Researchers Joanna Masel and Etienne Rajon found that tiny populations evolve global solutions to prevent errors, while large populations rely on local solutions to tolerate mistakes. This discovery reveals the importance of 'cryptic variation' in natural selection, allowing organisms to adapt to new challenges.
NASA's Aqua satellite captured visible and infrared images of Cyclone Wilma, revealing a clearly visible eye. The storm had strengthened overnight and showed strong convection around its center.
Researchers at the University of Gothenburg have used DNA technology to describe and register a new species of ribbon worm. The development of this method could lead to faster and more efficient species registration, with potential benefits for understanding biological diversity.
A study found that couples with matching language styles, including function words, were more likely to want future contact and stay together. The research used computer programs to analyze conversations and online chats between dating couples.
Researchers found that N-acetylcysteine can decrease the size of von Willebrand factor multimers in mice, potentially treating life-threatening blood disorder thrombotic thrombocytopenic purpura (TTP). However, chronic use of drugs targeting Notch1 raises concerns due to its link to vascular tumors and lethal hemorrhage in mice.
A recent study found that exposure to traffic noise increases the risk of stroke, especially in individuals aged 65 and over. The researchers discovered a significant association between road traffic noise and stroke risk, with an estimated 8% of all stroke cases potentially attributed to traffic noise.
A team of UCLA researchers has developed a chemically defined culture medium that supports the long-term quality and maintenance of human embryonic stem cells. The new medium, using a feedback system control scheme, eliminates the need for animal products and enables routine single-cell passaging.
Patients with hydrocephalus and white matter changes who underwent shunt operations showed significant improvements in mental function and walking ability. The study's findings provide conclusive evidence for the effectiveness of shunt surgery in treating this condition.
23andMe has completed its Independent Sarcoma Scientific Advisory Committee, comprising leading researchers and clinicians, to advance understanding of sarcomas. The company aims to combine genetic data with patient-reported outcomes to find patterns in sarcoma biology and treatment response.
Researchers used soap films to solve variational mathematical problems, which are crucial in physics, by finding the shape that minimises elastic energy. This innovative procedure was applied to classic problems like the brachistochrone curve and catenary, offering a fun and educative approach.
A new study found that implementing provider-based recall for immunizations is challenging due to lack of awareness and perceived difficulties. However, strategies such as dedicated staff and recalling children under two years old can facilitate recall initiation. The study suggests alternative approaches like population-based recall m...
Research identifies miR-143 and miR-145 as downregulated biomarkers in esophageal squamous cell carcinoma, showing anti-oncogenic activity. These findings suggest that microRNAs may serve as useful biomarkers for early detection and therapeutic targets.
The MalERA initiative outlines priority research areas for eight thematic areas, including basic science and enabling technologies; drugs; vaccines; vector control; health systems; and more. The collection identifies common research priorities across themes, providing a roadmap for malaria eradication.
A study published in PLOS Medicine found that only a third of births in rural Zambia occurred at a health facility, with half of mothers living over 25 km from basic emergency obstetric care. The level of care at the facility significantly influenced the odds of facility delivery.
Researchers have developed a new method to improve the thermoelectric performance of p-type half-Heusler, a common bulk semiconductor compound, using nanotechnology. The approach resulted in a significant increase in the figure of merit, paving the way for cleaner energy products such as car exhaust systems and power plants.
A new study suggests that converting to clean, renewable energy sources is technologically and economically feasible within 20-40 years. The plan involves using wind, water, and solar power to generate electricity, with a focus on combining these sources to overcome variability challenges.
Researchers at North Carolina State University have developed a new technique to reduce defects in gallium nitride (GaN) films used in LED lighting, increasing efficiency by a factor of two. The technique involves embedding voids in the film, which traps defects and prevents them from traveling through the material.