Researchers at Rhode Island Hospital tested spinal cord stimulation in a single patient with Parkinson's disease, finding that low-frequency SCS worsened symptoms while high-frequency SCS improved motor function. Further studies are needed to confirm these findings and explore potential benefits of this approach for PD patients.
A new comic book aims to promote healthy lifestyles among migrant families, particularly Latina mothers. The 'Small Changes Big Results' comic book offers practical tips on nutrition and exercise, targeting a high percentage of overweight or obese children in these communities.
Scientists have found a much higher water content in the Moon's interior, with concentrations ranging from 64 parts per billion to 5 parts per million. The research suggests that water was preserved from the hot magma present when the Moon formed 4.5 billion years ago.
Researchers found that brain's representation of hands is out of sync with reality, with fingers perceived as shorter and hands fatter. The findings may be relevant to psychiatric conditions involving body image.
The MINOS experiment has measured the parameters governing antineutrino oscillations with world-record precision, revealing a significant difference between neutrino and antineutrino masses. This finding challenges current theory and suggests a fundamentally new property of the neutrino-antineutrino system.
Research on prion disease found that structural differences affect transmission between species, while gene therapy showed promise in nonhuman primates. Additionally, the protein periostin was discovered to promote heart valve degeneration by inducing angiogenesis and MMP production.
A New York University study found that children living in areas where homicides are committed have lower reading and verbal test scores. The research suggests that violence can impact children's cognitive skills, regardless of whether they witness it directly or are personally victimized.
A new study found that 18% of U.S. cancer survivors, or over two million individuals, are not getting one or more needed medical services because of financial worries. Cancer survivors under 65 were more likely to delay or forgo all types of medical care than their peers without a history of cancer.
An estimated 1.8 million individuals visit free clinics annually, providing a range of preventive and general medical care to 10% of the working-age adult uninsured population. Free clinics rely on charitable donations, civic groups, and corporations as primary funding sources.
System 92L is showing signs of organization in the Atlantic Ocean, with strong convection and cold thunderstorms. The National Hurricane Center gives it a 60% chance of developing into a tropical depression within the next two days.
A study by UC Davis researcher Joshua Fenton found that use of computer-aided detection (CAD) in mammography screenings surged after Medicare began covering its cost. The prevalence of CAD increased from 5% to 27% between 2001 and 2003, despite uncertainty over its clinical impact on breast cancer outcomes.
Researchers at the University of Leeds have found a protein, CLC-5, that plays a crucial role in treating Dent's disease, a rare genetic disorder causing kidney stones and failure. The study reveals that faulty CLC-5 delivery impairs endocytosis, leading to vitamin and hormone loss.
Research reveals a significant association between sleep-disordered breathing and cardiovascular disease, with pro-thrombotic biomarkers PAI-1 and fibrinogen showing increases in relation to SDB severity. The study suggests that even mild levels of SDB may pose an enhanced risk for cardiovascular disease.
Research found that adding straw residue to hairy vetch cover crops can reduce legume nitrogen losses, but may lower crop yields. The study revealed that straw residue reduced soil inorganic nitrogen content by an average of 7.3% compared to treatments with only legume residues.
A Duke University engineer, Adrian Bejan, argues that animal movement is like a natural wheel, distributing stresses uniformly. As animals evolve to move better, they develop fewer legs, allowing them to rise higher with each stride and increase their speed.
A comprehensive survey of free clinics in the US found that they provide an estimated 3.1 million medical visits and nearly 300,000 dental visits annually, filling gaps in the health safety net for low-income patients.
A study found that genetic variants and neuroimaging measures are associated with Alzheimer's disease risk, providing new insights into the condition's mechanisms. The research identified three new genetic loci linked to Alzheimer's disease, as well as two new targets for future study.
Researchers in New Zealand studied transport of microbes from cow pastures into groundwater supplies and found little to no transport due to spray irrigation application. Spray irrigation was shown to significantly reduce the risk of microbial contamination of groundwater, contradicting previous findings on flood irrigation.
A study by Adriano Aguzzi and Christina Sigurdson found that the local structure of PrPC protein influenced prion transmissibility between different species. The researchers identified a molecular switch controlling interspecies prion disease transmission in mice, providing new insight into food safety risks associated with BSE.
Early-stage age-related macular degeneration is associated with modifiable risk factors like smoking and low HDL cholesterol. The study found that the condition becomes more common with age, especially in those over 65, while lower HDL cholesterol levels increase the risk.
A new study reveals that certain T cells delay their arrival to fight tuberculosis-causing bacteria, reducing the immune response. Regulatory T cells activate at the same time as effector T cells, hindering the body's ability to combat TB.
A new report found that high-yield crop varieties developed during the Green Revolution have helped keep greenhouse gas emissions at bay, avoiding nearly 600 billion tons of CO2. The study estimated that agricultural research has averted carbon dioxide emissions at a cost of about $4 per ton of CO2.
A new study published in Neurology found that mentally active lifestyles may reduce the negative effects of brain damage on learning and memory in people with multiple sclerosis. Participants with enriching lifestyles showed better scores on tests of learning and memory despite higher amounts of brain damage.
A study found that genetic mutations and pesticide exposure interact to increase men's risk for Parkinson's disease. Individuals with two variant alleles of the ABCB1 gene who were exposed to organochlorine insecticides had a stronger association with Parkinson's disease.
Scientists and engineers from NASA and NOAA worked together to recover the Solar X-Ray Imager instrument on GOES-15, which finally came online on June 3. The team conducted long-duration turn-on tests and successfully captured several test solar images after overcoming a challenging recovery process.
Researchers at the University of Leicester have found that CT scans can monitor progression of severe asthma and check how it responds to treatment. The study suggests that CT-derived measures of structural changes in lungs and airways may be used as a non-invasive marker for asthma.
Clinical guidelines recommend screening low-risk women every three years after age 30, but most primary care clinicians advocate for more frequent testing. Annual Pap testing has helped decrease cervical cancer burden, but cost-effectiveness models suggest overuse may increase costs with little improvement in outcomes.
Researchers found that carnivores can track yearly differences in rowan fruit abundance and prefer the most productive trees. They also helped disperse seeds by picking up fallen fruit, suggesting a symbiotic relationship between carnivorous mammals and plants.
Plants perceive nutrient availability through NRT1.1 nitrate transporter stimulation, inducing lateral root growth in nitrate-rich patches. This mechanism regulates root branching by controlling auxin accumulation, demonstrating a connection between nutrient and hormone signaling during organ development.
Researchers deciphered a key pathway used by Myc oncogene, finding that disabling it can restore cellular senescence and prevent cancer growth. This discovery offers new potential for treating various types of cancer by targeting the oncogene's dependence on Miz1.
A recent study uses genomic analysis to understand complex cellular signals driving lung cancer's deadly spread. The research identifies specific molecules linked to non-small cell lung cancer's (NSCLC) invasive and metastatic processes, providing a basis for effective therapies.
A new study published in the American Journal of Preventive Medicine found that adults' moderate to vigorous physical activity is linked to neighborhood characteristics such as residential housing density and connected streets. Most physical activity occurs within a 1-kilometer buffer zone around their homes.
UCB has announced an oral solution formulation of Vimpat (lacosamide) C-V, expanding treatment options for people with epilepsy. The new formulation is available in three forms, including oral solution and IV injection, allowing patients to maintain consistent treatment across various clinical settings.
A new study published in Marketing Science found that combining eye-catching pop-up graphics with targeted ads can lead to a decrease in consumer recall and purchase plans. The study suggests that high-visibility ads are more effective for consumer recall, while content-linked ads promote higher purchase intentions.
New research on tequila and Comte cheese GIs highlights the importance of product quality, terroir protection, and regional development. The study finds that the tequila GI's lack of guidance on production methods leads to industrialization and erosion of traditional character.
A new manifesto calls for a radical change in the global innovation agenda to address poverty, environmental degradation, and inequality. The report recommends policies to increase transparency, accountability, and inclusive innovation, with diverse stakeholders involved.
Researchers elucidated the basic principles of bacterial transport channel assembly, a mechanism used by pathogens to deliver virulence factors. The discovery opens doors to developing anti-infective drugs that can target this process before antibiotics, offering a major advantage in infection treatment.
A new CU-Boulder study provides further support for the idea of a sustained sea on Mars during the Noachian era, suggesting an ancient ocean likely covered about 36% of the planet. The research implies an Earth-like global hydrological cycle, including precipitation, runoff, cloud formation, and ice and groundwater accumulation.
Scientists at Massachusetts General Hospital have developed a technique to grow transplantable replacement livers using the structural tissue of rat livers. The approach involves decellularizing the liver and reseeding it with liver cells, resulting in normal liver function for up to 10 days in culture.
Cardiologists at University Hospitals Case Medical Center have discovered a significant association between angiotensin-receptor blockers (ARBs) and an increased risk of new cancers. The meta-analysis found that patients taking ARBs had a 8-11% higher risk of developing new cancer compared to those taking control medications.
A meta-analysis of publicly available data from randomised trials found that patients taking ARBs had a significantly increased likelihood of new cancer diagnosis compared with patients in control groups. The study also found a modestly increased risk of lung cancer among ARB users, but no significant excess in cancer deaths.
A study of 15,162 children born after assisted reproduction found a major congenital malformation rate of 4.24%, exceeding previous estimates. The majority of malformations were heart diseases and uro-genital system disorders, with a five times higher rate of angioma in girls.
Researchers generally agree that genetic variation findings should be shared with participants if clinically significant, but confidence levels vary across disciplines and conditions. The study highlights the complexity of this issue, suggesting that factors beyond scientific robustness influence researchers' decisions on disclosure.
A team of researchers from the University of Miami and NOAA successfully located a 23-mile long oil plume off Florida's Treasure Coast, heading towards the Dry Tortugas. Using advanced models, satellite images, and shipboard observations, they identified the oil slick and its potential pathway.
A small genetic change in the IL28B gene can predict how well individuals with hepatitis C will respond to treatment. Those carrying this protective allele are more likely to clear the virus and respond to therapy.
A new high-temperature heat pump technology has been developed to tap into geothermal energy sources, providing a renewable and inexhaustible energy supply. The system uses waste water from geothermal wells, reducing dependence on fossil fuels and CO2 emissions in European towns.
Dr. George Stark receives prestigious lectureship for outstanding lifetime scientific contributions, spanning basic biochemistry and specialized fields like gene regulation and cell signaling.
Researchers at the University of Oklahoma Health Sciences Center have found a way to use gene therapy to treat retinitis pigmentosa, an eye disease that causes blindness. The treatment involves delivering genetic therapies directly to light-sensitive cells in the retina using nanoparticle technology.
A University of Pennsylvania psychologist reanalyzes data suggesting that the brain does not consume extra glucose when exerting self-control, contradicting a popular model. The analysis also suggests that any potential decrease in glucose levels may be due to other factors, such as increased heart rate.
A new microbial genetic system has been developed to dissect biomass to biofuel conversion, allowing for the efficient extraction of sugar molecules from biomass polymers. This breakthrough enables researchers to study the functional significance of specific enzymes and understand how microorganisms carry out the complex process of pla...
Researchers found that mortality rates were significantly lower among patients who received DOT from a nominated treatment supporter compared to self-monitored ART. The study suggests that social capital and emotional support provided by these supporters contributed to improved survival outcomes.
UAB researchers are investigating the role of inactivated DNA left behind after breast-cancer treatment. They aim to understand how this altered DNA activates cancer's deadly spread, a process called metastasis. The study could lead to improved prevention and treatment for millions of cancer patients.
Movshon and Stanford's William T. Newsome receive award for their decades-long research on how the brain reconstructs images to support perception, linking perception to specific neural activity
A new test of sense of smell may help diagnose and treat early-stage Parkinson's disease. The research used transgenic mice with high levels of human alpha-synuclein, a protein linked to PD, to develop a model for studying the disease's effects on dopamine regulation.
The article explores issues related to cosmetic surgery, body image, and sexuality, highlighting the lack of proper information on risks and complications. It also examines the controversy surrounding the use of resources for these procedures, particularly in developing countries.
A University of Houston sociologist chronicles the Gülen Movement, an Islamic civic movement that promotes peace, education, and interfaith dialogue. The book presents stories from participants who benefited from Gülen-inspired schools, highlighting its positive impact on communities.
A Mayo Clinic study found that interrupting blood flow for more than 20 minutes during kidney cancer surgery increases the risk of chronic kidney disease. Limiting ischemia time can help avoid this complication.
The NASA Aqua satellite captured an image of the thickest part of the oil slick in the Gulf of Mexico on June 10, 2010. The MODIS instrument revealed a sun-glint effect where the oil slick appeared nearly white due to smooth water surfaces.
A study of 193,804 trauma patients found that uninsured individuals were more likely to die from injuries than those with private insurance. Patients covered by Medicaid or other insurance plans had better mortality rates for all injuries compared to those without insurance.
A high-resolution Asian monsoon record was established covering the time range from 16.2 to 7.3 ka BP, revealing key information on past climatic changes and their mechanisms. The study confirms earlier work suggesting that solar insolation and North Atlantic climate affect the Asian Monsoon.