Articles tagged with Myocardial Infarction
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Half of myocardial infarction patients report onerous fatigue four months after the event, with depression symptoms also common. Patients' perceptions of their illness play a crucial role in determining prognosis and treatment effectiveness.
Patients with both obesity and diabetes face a significantly worse prognosis, with effective treatment being
Aspirin use in primary prevention reduces non-fatal heart attacks by around 12%, mainly due to reduced risk of non-fatal heart attack. However, it also increases the risk of internal bleeding by around a third in healthy individuals.
Researchers found that glucocorticoids induce production of PGD2, which protects rodent hearts from ischemia/reperfusion injury. Synthetic glucocorticoids may be more beneficial for humans following a heart attack than traditional ones.
A new study comparing three different types of aspirin has found that chewable aspirin consistently shows greater and more rapid absorption, potentially leading to improvements in heart attack care. Researchers measured blood levels of aspirin after administering regular and chewed aspirin to volunteers.
A landmark follow-up study found that ICDs reduce the risk of death from any cause by 37 percent in heart attack survivors, translating to 1.2 life-years saved, and greatly amplifying their value as a chronic therapy.
A meta-analysis of studies on aspirin therapy found a 12% reduced risk of nonfatal stroke in patients with peripheral artery disease, although this finding was not statistically significant. Aspirin monotherapy was also associated with a lower risk of nonfatal stroke, but no significant reductions were seen in other cardiovascular events.
A study found African-Americans at greater risk after PCI with significantly worse outcomes, despite researchers' efforts to provide optimal care. Possible explanations include delayed treatment, advanced coronary disease, and poor medication adherence.
Two studies show that women who undergo angioplasty for heart attacks are often older, in poorer condition, and have delayed recognition of symptoms. As a result, they face twice the likelihood of procedural failure and an increased risk of death compared to men.
Researchers found that heart attack patients who develop serious arrhythmia during procedures face a significantly higher risk of death for several months after the procedure. The study suggests that these episodes complicate outcomes and affect a patient's chance of a successful outcome.
Researchers have identified a specific gene and protein that contribute to the development of deadly arterial plaques. Deleting this gene in mice resulted in smaller, less unstable plaques. The study suggests that therapies targeting cellular stress may be useful in treating heart disease.
Certain patients with heart attack who experience abnormal heart rhythms before or after a coronary artery intervention have a significantly higher risk of death within 90 days. VT/VF episodes were more common in late catheterization and associated with lower blood pressure, higher heart rate, and lack of beta-blockers.
Patients with cardiac health problems are trialing a new, home-based rehabilitation system that uses mobile phone and web technology to promote healthy lifestyles. The program aims to improve access and completion rates for cardiac rehabilitation, with personalized goals and support via text messages and video conferencing.
Researchers found that men with highest increase in heart rate during mild mental stress had twice the risk of dying from a heart attack. The study suggests cheap and easy ways to predict who might be at risk, using pulse measurement as a prognostic marker.
A study published in the Biophysical Journal has discovered a method to predict heart attacks by measuring electrical activity coupling between two types of heart muscle cells. This can help doctors and patients buy time before an attack occurs.
Postmenopausal women who breastfed for at least a month had lower rates of diabetes and high cholesterol. Longer durations of breastfeeding resulted in significant reductions in heart attack risk, with those nursing for over a year being 10% less likely to develop cardiovascular disease.
A study found that consuming fructose-sweetened beverages increased intraabdominal fat and decreased insulin sensitivity, while glucose-sweetened beverages had no significant effects. This suggests that fructose may be more detrimental to health than glucose.
A new study published in the Journal of the American College of Cardiology: Cardiovascular Interventions found that organized STEMI networks consistently provide the fastest treatment of acute heart attacks, with 86% of patients receiving skilled coronary intervention within 90 minutes. This improvement surpasses the American College o...
Researchers at Duke University Medical Center used new imaging technology to discover nearly 200,000 people in the US suffer 'silent' heart attacks each year. These unrecognized myocardial infarctions are linked to a surprisingly high risk of untimely death and may be more common than previously believed.
The UCLA center aims to prevent second strokes in survivors by exploring innovative models of care and neighborhood interventions that reduce risk factors. Researchers will collaborate with community partners on studies to develop effective preventive treatments.
A study found that screening patients with type 2 diabetes for coronary artery disease (CAD) did not significantly reduce the rate of heart attacks or cardiac death. However, participants with normal results had lower event rates than those with abnormalities, suggesting the importance of appropriate diagnostic evaluation.
Researchers created a new method to estimate bleeding risk for heart attack patients using eight basic medical facts. The CRUSADE bleeding score assigns points to each factor, ranging from very low to high risk of bleeding.
Researchers at UT Southwestern Medical Center found that the protein Thymosin beta-4 initiates migration of heart cells and blood vessel growth after a heart attack, encouraging new growth and repair of damaged heart cells. The molecule affects developmental gene expression as early as 24 hours after systemic injection.
Telemonitoring is being integrated into cardiac nursing practice to improve heart failure management. The technology enables nurses to remotely monitor patients' vital signs and provide guidance on lifestyle changes and medication.
A University at Buffalo study reveals that two oral pathogens, but the total number of germs, are associated with an increased risk of heart attack. The study found that patients harbored more periodontal bacteria than controls, and that an increase in the number of different species also elevated heart attack odds.
Researchers at Duke University Medical Center discovered a missing enzyme that can resist the normal effects of a heart attack, allowing mice to retain nearly normal heart function. The findings suggest a potential therapy for stimulating blood vessel growth and preventing future attacks.
Researchers found that treating patients with their own bone marrow stem cells after a heart attack increased circulation within the heart. The study showed that higher doses of cells led to greater improvement in blood flow, but results for cardiac function were not significant.
The study found that administering eptifibatide in the emergency room or during procedures to open blocked arteries does not significantly affect patient outcomes for those at high risk of complications after a heart attack. Researchers also noted an association between earlier use of eptifibatide and non-life-threatening bleeding.
A study of over 1,000 CAD patients found that high PLTP levels increased the risk of heart attack in statin users. Elevated PLTP levels may blunt statin benefits, according to researchers.
Research suggests that air pollution is a significant contributor to heart disease, particularly among the elderly, those with coronary artery disease, diabetics, women, and obese individuals. Exposure to particulate matter can increase blood pressure, activate enzymes that cause plaque rupture, and lead to a heart attack.
Researchers estimate that around 6.5 million older adults with low cholesterol and high C-reactive protein levels might benefit from statin therapy to prevent cardiovascular events. Expanding prescribing criteria to include CRP levels could potentially prevent thousands of heart attacks, strokes, and deaths each year.
The USPSTF updated its guidelines to recommend aspirin use for primary prevention of heart attack and stroke in specific age and gender groups. The task force emphasizes the importance of discussing the benefits and risks of daily aspirin use with patients, particularly those between 45-79 years old.
Researchers at Thomas Jefferson University identified a novel signaling pathway mediating aldosterone production, which promotes heart failure. Blocking beta-arrestin-1 could lead to lower aldosterone levels and alleviate negative remodeling processes in the injured heart.
The US Preventive Services Task Force (USPSTF) recommends taking aspirin in at-risk patients to prevent heart attacks and strokes. However, the quality of care in nursing homes remains suboptimal, and creating a specialized physician training program may help address this issue.
A German study found that people who have had a heart attack are more than three times as likely to have been in traffic within an hour of their symptoms. Driving or riding in heavy traffic poses an additional risk of eliciting a heart attack, especially for females, elderly males, and those with a history of angina.
Researchers found that up to 45% of individuals without known heart disease had abnormal ankle brachial index values, indicating peripheral arterial disease. This could improve cardiovascular risk prediction and identify high-risk patients for intensive medical therapy.
Two studies found that SOX9 renders melanomas sensitive to retinoic acid, stopping tumor growth and offering new hope for effective treatment. Additionally, researchers identified two enzymes crucial for ureter-bladder connection during development, which may hold key to treating congenital anomalies.
Researchers found a link between CaM kinase II inhibition and reduced inflammatory gene expression in heart muscle cells. Inhibition of CaM kinase II protected mice from heart damage, highlighting a potential new treatment target.
Research identifies elderly patients with multiple cardiovascular risk factors as higher risk for stroke and heart attack after IVIg treatment, while those with fewer risk factors have lower likelihood. The study provides guidance for physicians counseling patients on IVIg treatment risks.
A new study in Annals of Internal Medicine found that patients connected to a specific primary care physician are more likely to receive guideline-consistent care than those without a connection. Researchers also discovered that connectedness was associated with smaller disparities in screening rates, but not race or ethnicity.
Researchers found increased PAI-1 expression in the heart of mice with diabetes leads to profibrotic effects, including increased fibrosis and functional derangements. This link may contribute to the high incidence of heart failure after myocardial infarction in people with diabetes.
A new study by Duke University Medical Center reveals that delayed treatment for heart attacks using drugs alone is as effective as treatment with stents, offering a cheaper and less invasive option. The research found modest benefits in reducing chest pain but no long-term quality of life difference between the two approaches.
Researchers found clusters of genetic markers linked to early heart attack risk, including nine genes associated with increased MI risk. The study suggests new gene sites affecting coronary heart disease and early heart attack risk, with potential for earlier intervention.
A study by UC Irvine researchers found that individuals with high systolic and low diastolic blood pressures are at a greater risk of heart attack and stroke. The combination of these two blood pressure components is a superior predictor of future adverse cardiovascular events.
Researchers have identified novel genetic markers associated with an increased risk of heart attack, which are more than twice as great in individuals carrying multiple genetic markers. The study found that genes on chromosomes 3 and 12 play a crucial role in cardiovascular biology.
A new study has found a potential link between a gene variant and the risk of stroke and heart attacks in women who experience migraines. Women who carried certain genotypes were found to be at double the risk of stroke and heart attacks, while those with other genotypes were not. Further research is needed to confirm these findings.
Scientists have identified a shared genetic predisposition between aggressive periodontitis and myocardial infarction, with a common genetic variant on chromosome 9. This discovery highlights the importance of considering periodontitis as a potential risk factor for cardiovascular disease.
A new critical care pathway, ACSETS, was implemented at four western New York hospitals to improve treatment and outcomes for patients with acute coronary syndrome. The study found that ACSES patients had a 19% lower mortality rate one year after discharge compared to pre-ACSES patients.
Researchers found that half of men with high cotinine levels lived with a partner who smoked, increasing their risk of heart attacks. Despite declining smoking rates in the UK, living with a smoker remains a significant risk factor for non-smokers.
A study published in Archives of Internal Medicine found that multivitamin use was not associated with an increased risk of breast, colorectal, or cardiovascular diseases in postmenopausal women. No significant associations were found between multivitamin use and cancer or cardiovascular disease mortality rates.
New research published in JACC found that patients have a better chance of survival when both their hospital and physician have a strong track record in treating heart attacks with angioplasty and stenting. High-volume hospitals and physicians performed significantly better, with lower risks of in-hospital death.
A large international study identified nine genetic regions linked to increased risk of early-onset myocardial infarction. The study analyzed data from 26,000 individuals in 10 countries and found significant associations with common single-nucleotide polymorphisms (SNPs) in nine genetic regions.
Researchers at Washington University School of Medicine identified a gene that controls protein translation in microscopic worms, allowing them to survive in low-oxygen environments. This discovery has implications for conditions like stroke, heart attack, and cancer, and may lead to new therapies for preventing cell death from hypoxia.
A new study found that proton pump inhibitors significantly increase the risk of heart attacks in patients taking clopidogrel after a heart attack. The risk was higher for certain proton pump inhibitors, including omeprazole and lansoprazole.
Researchers found a significant drop in severe heart attack symptoms, including electrocardiogram abnormalities and biomarker levels. These findings suggest that better control of risk factors and hospital management contributed to the decline in deaths from coronary heart disease.
Researchers capture images of bleeding inside heart muscle after heart attack using MRI scans, finding correlation between bleeding and extent of heart damage. Patients with larger heart attacks show more significant bleeding and poorer recovery chances.
A new diagnostic tool can help doctors determine whether stenting is necessary for patients with coronary artery disease. The study found that using this tool resulted in a significant reduction in cardiac events, including death, heart attack, and repeat stenting or bypass surgery.
A new national study shows that nearly 75 percent of patients hospitalized for a heart attack had cholesterol levels within recommended targets, but still at high risk. The study suggests that lowering guideline targets for LDL cholesterol and developing better treatments to raise HDL cholesterol may help reduce the number of patients ...
A study published in CMAJ found that men with type 2 diabetes have a 3-fold risk of cardiovascular mortality compared to those without either condition. In the long term, however, the two groups had similar mortality risks.
A genetic variation affecting the CYP2C19 enzyme makes anti-clotting drug clopidogrel less effective in young heart attack patients, increasing risk of death, another heart attack, or stent thrombosis. Carriers of the gene variation are four times more likely to experience cardiovascular events than non-carriers.