Articles tagged with Obesity
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The team is creating a virtual gut system to test chemical reactions and networks, which will help identify the best treatments for obesity. The MATOMIC project aims to develop mathematical models that can simulate the intestinal microbiome at an atomic level.
A new study found that a fully-automated online behavioral obesity treatment program led to significant weight loss among participants, with an average 12-week weight loss of 5.10%. The program addressed barriers in primary care, including limited resources and overburdened providers.
A pooled data analysis of 11 international studies found that NAFLD is associated with a 50% heightened risk of developing heart failure. The severity of NAFLD also increases the risk, especially with extensive liver fibrosis.
A new analysis led by University of Pittsburgh School of Public Health epidemiologists found that adults who undergo bariatric surgery are more than twice as likely to get married within five years. Conversely, married patients who receive bariatric surgery are more than twice as likely to get divorced.
A study by Imperial College London found that 64% of calories in school lunches come from ultra-processed foods, contributing to childhood obesity. The analysis revealed higher levels of processed foods in packed lunches and secondary school meals, with lower-income children more likely to consume them.
Research found that acidic activated charcoal from Shinshu Ina's specialty Akamatsu tree suppresses weight gain due to a high-fat diet by increasing bile acid, cholesterol, triglyceride, and fatty acid excretion. No damage to the gastrointestinal mucosa or lungs was observed.
Researchers found that healthy underweight individuals consume 12% less food and are 23% less active than those with normal BMIs. They also have higher resting metabolic rates, suggesting that low body fat may trump physical activity in downstream consequences.
A new study found that children's food choices are influenced by their emotional states, particularly during weekends. Children reported consuming more sweet foods and sugary beverages when stressed or sad.
A study published in Environmental Research found that prenatal exposure to specific phthalates is associated with a slightly elevated risk of children starting puberty between 7 and 10 years old. Higher prenatal exposure to certain phthalates, such as DEHP, was linked to an increased risk of puberty onset, particularly in normal-weigh...
The American Society for Nutrition (ASN) emphasizes that all methodologies in nutrition research contribute to the discipline and advance health and well-being. The ASN-commissioned white paper reviews various methodologies used in nutrition research, highlighting their strengths, limitations, and interpretations.
A long-term high-fat diet has been shown to cause significant weight gain and metabolic disorders in mice, leading to anxiety, depression, and worsening Alzheimer's disease. The study suggests a clear link between chronic obesity and diabetes with cognitive decline.
Researchers from Tianjin Medical University General Hospital review sarcopenic obesity's impact on liver disease, including nonalcoholic fatty liver disease and cirrhosis. The study aims to clarify the pathogenesis of sarcopenic obesity and identify potential therapeutic avenues.
Eating one avocado a day for six months improved overall diet quality by eight points and slightly decreased LDL cholesterol levels. However, avocados had no effect on belly fat or weight gain in participants with overweight or obesity.
A recent study published in International Journal of Molecular Sciences reports the successful testing of Pep19, a synthetic peptide with anti-obesity action. The molecule was found to mitigate weight gain while reducing insulin resistance and liver fattiness in mice fed a high-fat diet.
A study published in Cell Reports found that a rhythmic small intestinal microbiome prevents obesity and type 2 diabetes in mice. The researchers used mouse models to explore how diet and feeding patterns affect the gut microbiome and its impact on host health, particularly with obesity and type 2 diabetes.
A new molecule, inosine, has been identified as a key booster of fat burning through activation of brown fat cells. Studies have shown that inosine can increase energy consumption and protect against diabetes in mice fed high-energy diets.
A new study reveals that areas once 'redlined' in the 1930s continue to suffer from higher rates of cardiometabolic health risk factors, including obesity, diabetes, and high blood pressure. Neighborhoods with lower grades on historical redlining maps had better access to healthcare and lower rates of disease.
A study by Tufts researchers found that only 6.8% of US adults had optimal levels of blood pressure, blood sugar, cholesterol, adiposity, and cardiovascular disease in 2017-2018. The prevalence of these conditions worsened significantly between 1999 and 2018, with large disparities across sex, age, race, ethnicity, and education levels.
A recent study published in The Lancet Diabetes & Endocrinology found that COVID-19 vaccines significantly reduced severe disease cases across all BMI groups. Vaccine effectiveness was slightly lower in underweight individuals, but substantial reductions in risk were observed for those with healthy weights and higher BMIs.
New research reveals NHS weight policies are associated with a decline in knee replacement surgery rates, disproportionately affecting less affluent groups. The study found that regions introducing BMI-based policies saw a decrease in surgery, potentially worsening health inequalities.
Researchers identify AgRP neurons as key players in regulating food intake by releasing endogenous lysophospholipids, which stimulate cerebral cortex activity. Administering autotaxin inhibitors can significantly reduce excessive food intake and obesity in animal models.
Researchers at Joslin Diabetes Center and Brigham and Women's Hospital found that cold exposure can resolve obesity-induced inflammation while improving insulin sensitivity and glucose tolerance in diet-induced obese mice. Brown adipose tissue is activated to produce anti-inflammatory molecules, including Maresin 2.
Research reveals associations between cardiovascular risk factors, low physical fitness, and decreased neural activity in the social brain network, leading to social cognitive function decline. A healthy lifestyle may mitigate this decline through targeted interventions.
A new study reveals that more than half of American adults gained 5% or more body weight over a 10-year period, while women and Black women experienced the greatest average weight gain. The study's findings highlight the need for targeted interventions to address obesity in high-risk groups.
A narrative review of endoscopic sleeve gastroplasty (ESG) highlights its potential as a minimally invasive weight loss procedure. The review concludes that ESG induces significant weight loss and improves obesity-related conditions, with the technique's success attributed to delayed gastric emptying. Researchers support the use of ESG...
A study of 552 older adults found that those exposed to light during sleep were significantly more likely to develop obesity, high blood pressure and diabetes. The study suggests that minimizing light exposure at night can help prevent these conditions.
A recent study found that socioeconomic disparities in obesity among US adolescents have significantly increased over the past two decades. The findings suggest that adolescents from lower-income backgrounds are more likely to be obese, highlighting a pressing public health concern.
This supplement explores the complex contributors to obesity and obesity-related health disparities, highlighting the role of social determinants, behavioral factors, and biological influences. Researchers propose strategies for improving population wellbeing and inform healthcare and public policy approaches.
A new study links polycystic ovary syndrome (PCOS) to an increased risk of adverse cardiovascular events and pregnancy outcomes during delivery, including preeclampsia and peripartum cardiomyopathy. Women with PCOS are at a higher risk for heart complications compared to those without the hormone disorder.
A long-term study found that bariatric surgery improves physical activity and diet quality in participants, but only a small percentage meet federal guidelines. Patients may need continued support to maintain weight loss and health benefits after surgery.
Researchers found that using analytical language when describing weight loss goals led to greater weight loss success and lower dropout rates. Analytical language, such as focusing on what's important and why, was associated with more weight loss and less program attrition.
Researchers identified a molecule called Lac-Phe that suppresses food intake by 50% in diet-induced obese mice. Lac-Phe also improves glucose tolerance and reduces body weight, paving the way for potential exercise pills to treat obesity and related conditions.
Researchers have developed a test that measures blood levels of ceramides, a waxy substance similar to cholesterol, to predict diabetes remission in gastric bypass surgery patients. The study found that individuals with low ceramide levels prior to surgery had a higher likelihood of achieving diabetes remission two years later.
Scientists at CNIC discovered a complex network between liver tissue connections that allows the liver to regulate body temperature. The secretion of IL-12 by liver-infiltrating macrophages blocks FGF21 production, reducing heat generation by brown fat in mice.
A new study found that women with obesity have suppressed ovarian follicle development and reduced production of reproductive hormones, which may underlie reduced fertility. The researchers also discovered that luteal phase defects are more prevalent in obese women during natural ovulatory cycles.
A new study found that teens' consumption of ultra-processed foods decreased significantly during the COVID-19 pandemic and continued to decline even after restrictions eased. This reversal took place due to changes brought by the pandemic, including school closures and working from home.
A study by the University of Queensland found that obese patients were up to 17.3 times more likely to undergo a knee replacement than their healthy weight counterparts. Modest weight loss has been shown to effectively reduce knee OA symptoms, suggesting a potential solution to address the growing burden of revision knee replacements.
A recent study reveals that patients with lower body mass indexes (BMIs) could benefit from weight-loss surgery due to its effectiveness in treating type 2 diabetes and other comorbidities. The study found that patients with Class I obesity who underwent weight-loss procedures had shorter hospital stays, fewer complications, and improv...
A new study published in Pediatrics found that a 12-week app program improved children's motor skills by an average of 15.5 percentage points. The app-based program focused on six motor skills, including hopping, throwing, and jumping, and was shown to be effective in preventing childhood obesity.
A new study reveals that weight bias is pervasive across racial and ethnic groups, with Hispanic and Black adults experiencing it at higher rates. The study also found that nearly half of all respondents support laws against weight-based discrimination, highlighting the need for greater awareness and understanding of this issue.
Researchers found that weight-loss surgery patients saw significant reductions in several types of cancer incidence and improved survival rates compared to non-surgical patients. The 10-year incidence of any new cancer was lower and the 10-year survival rate was higher for bariatric group patients.
The primary causes of liver cancer are changing globally, with advances in hepatitis B vaccinations and antiviral therapies reducing HBV-associated liver cancer. However, alcohol consumption and obesity are rising, leading to increased liver cancer deaths. The incidence of NASH is projected to increase further due to rising obesity rates.
A customized WeightWatchers program has been shown to effectively manage Type 2 diabetes by lowering blood glucose levels and promoting significant weight loss. Participants in the six-month clinical trial experienced improved glycemic control and overall well-being, with clinically meaningful and statistically significant results.
A nationwide study found a significant association between excessive BMI in late adolescence and the development of type 1 diabetes in young adulthood. The researchers analyzed data from over 1.4 million adolescents and found that those with obesity had double the risk of developing type 1 diabetes compared to those with optimal BMI.
A Cleveland Clinic study found that bariatric surgery significantly reduces the risk of developing obesity-associated cancers and dying from cancer. The research, published in JAMA, showed a 32% lower risk of cancer development and a 48% lower risk of cancer-related death compared to non-surgical controls.
A recent study published at the Euroanaesthesia Congress found that patients with higher body mass index (BMI) and weight prior to bariatric surgery are more likely to experience complications and have worse outcomes. The research analyzed data from over 4,000 adults who underwent weight loss surgery between 2006 and 2020, revealing a ...
A study by NIH found that people with food allergies have a lower risk of becoming infected with SARS-CoV-2. In contrast, obesity and high body mass index (BMI) are associated with increased risk for SARS-CoV-2 infection.
A new mobile app provides effective support for children with obesity by tracking their weight development in real-time and offering personalized care. The app achieved twice the weight loss results compared to conventional care, particularly benefiting adolescents who were previously difficult to reach with behavioral therapy.
The US healthcare system faces a significant challenge in providing high-quality, personalized obesity care due to lack of insurance coverage for effective medications and societal stigma. Recent efforts aim to address this issue through framework development and policy changes, which may lead to improved patient outcomes and cost savi...
Virginia Tech scientists led by Sora Shin are investigating the brain pathways responsible for high-fat diet overconsumption. The study aims to identify a framework for understanding how leptin-responsive circuits respond to food exposure and increase the risk of emotional overeating after abstinence.
A recent study published in the Journal of Endocrinology suggests that lowering blood glucose levels can partially restore reproductive hormone levels and ovulation in female mice with obesity. The study used dapagliflozin, a common type 2 diabetes medication, to treat the mice, resulting in improved fertility outcomes.
Researchers analyzed mobile app data to gain insight into behaviors of middle-aged women living with severe obesity in urban poverty. The study found associations between anxiety and weight loss or gain, as well as correlations between location, timing, and eating/drinking frequency.
A recent study published in Clinical Nutrition Journal has established a strong link between sarcopenic obesity and dementia in elderly patients. The research found that individuals with sarcopenic obesity were more likely to experience cognitive impairment and dementia compared to those without muscle loss or obesity.
Researchers discovered that lean individuals with non-alcoholic fatty liver disease (NAFLD) are at a higher risk of developing cardiovascular diseases compared to those who are overweight or obese. Despite lower rates of other health conditions, lean patients with NAFLD exhibited increased prevalence of cardiovascular disease.
A new study found that crown-like structures surrounding breast tumors in overweight and obese patients can hinder their response to therapy. Researchers identified a potential molecular biomarker, CD32B, which is associated with poorer treatment outcomes.
A study published in Human Reproduction found that men with obesity who lost weight saw a 50% increase in sperm concentration and a 40% increase in sperm count over an 8-week period. This improvement was sustained for up to 52 weeks and even doubled for those who maintained weight loss after a year
Researchers at Marshall University Joan C. Edwards School of Medicine are studying the role of obesity and oxidative stress in Alzheimer's disease. Obesity is a key predictive factor for Alzheimer's disease, which affects 14 million Americans by 2060.
Researchers found obese and thin individuals misreport food intake by the same amount, contrary to official guidelines. The study suggests a reevaluation of public health recommendations, focusing on dietary risk factors rather than energy expenditure.
Researchers linked dietary cholesterol to exacerbation of viral infections in mice, showing that high levels of cholesterol made mice sicker when infected with influenza. The study found that dietary cholesterol increased the number of cytokine-producing immune cells in the lungs, contributing to excessive inflammation.
A new weight-loss intervention has been developed to target the instinctive desire to eat, particularly in individuals who struggle with resisting food cues. The Regulation of Cues program trains individuals to use natural hunger cues, reinforces tolerance of cravings, and inhibits urges to eat palatable foods when not physically hungry.