Articles tagged with Obesity
A comprehensive review of 169 clinical trials found that the effect of fructose-containing sugars on adiposity varies among food sources and energy control. High doses of certain sources, like SSBs, lead to increased body weight, while others, such as fruit and honey, show moderate beneficial effects when consumed in moderation.
A study published in Scientific Reports found that rats exposed to high-fat diets during pregnancy and early life developed a preference for salty taste. This preference was linked to increased levels of AT1 protein in the taste buds, which can lead to higher sodium intake and potentially contribute to obesity and diet-linked diseases.
Researchers found deaths from gallstone disease increased in younger populations and those with Medicaid after Medicaid expansion, highlighting the need for proactive prevention over reactive emergency care. A new healthcare model emphasizing primary care and prevention is proposed to address these inequities.
Researchers found that maternal overweight compromises the placenta's antiviral response, weakening its ability to protect the fetus. The study suggests that adequate antenatal care is crucial in preventing complications from Zika infection.
A study found that sleeve gastrectomy decreases bone mineral density and strength in adolescents and young adults. Participants who underwent weight loss surgery lost significant amounts of weight and experienced reductions in abdominal fat tissue and muscle mass.
A study from Tufts University researchers estimates that menu calorie labels can prevent at least 28,000 obesity-associated cancer cases and 16,700 cancer deaths over a lifetime, saving $2.8 billion in healthcare costs. The policy is expected to have the greatest impact on young adults and Hispanic/Black individuals.
A modelling study suggests that specifying menu calorie counts is likely to reduce obesity-related cancers and healthcare costs in the US. The policy could prevent 28,000 new cancer cases and 16,700 cancer deaths, as well as save $1.48 billion in medical costs.
A mouse study suggests that a specific brain receptor, the leptin receptor, may be involved in the development of PCOS symptoms. Researchers found that mice exposed to excess androgens prenatally had improved estrous cycles and regulation of their menstrual cycles, offering potential therapeutic targets for people with PCOS.
The CHEST journal April issue features cutting-edge research on asthma, chronic obstructive pulmonary disease (COPD), and sarcoidosis. Key findings include the potential of efzofitimod as a treatment for managing sarcoidosis. The journal also showcases innovative approaches to clinical practice and education in chest medicine.
A machine learning model has been developed to predict a patient's risk for a sleep disorder using demographic, lifestyle, physical exam results, and laboratory values. The model identified depression, weight, age, and waist circumference as the greatest predictors of a sleep disorder diagnosis.
Researchers found that higher selenium levels were associated with lower blood pressure and HDL concentration in middle-aged women. The study suggests that selenium may moderate the effect of genetic variants on MetS components, such as waist circumference.
A study of 308 adults found that people displayed more active and healthy behaviors during a three-day holiday, with increased physical activity and decreased sedentary behavior. The extra time off also led to improved sleep patterns, with participants gaining an average of 21 minutes of sleep per day.
A new study published in Metabolism reveals that the hormone neurotensin is released in greater amounts by people who successfully maintain weight loss after a low-calorie diet. This suggests that neurotensin may play a key role in regulating appetite and weight management.
Research explores how social norms and culture influence food preferences, physical activity behaviors and future hopes for community development. Key themes include the importance of creating interventions aligned with cultural norms to create effective and sustainable programs.
A study published in Diabetologia found that bariatric surgery can regenerate damaged nerves and improve metabolic risk factors related to diabetes. Peripheral neuropathy, a condition affecting over 30 million Americans, showed improvements two years after the procedure.
The new American Heart Association scientific statement emphasizes the importance of including non-biological factors and social determinants in CVD risk assessment for women. These factors include economic stability, neighborhood safety, education level, and access to quality healthcare, which disproportionately affect women from dive...
The University of Texas at El Paso will study the role of obesity and inflammation in pancreatic cancer development, a disease with high mortality rates. The grant aims to develop targeted treatments and preventives, potentially transforming understanding of pancreatic cancer.
Researchers from Karolinska Institutet found that people with obesity due to genetic predisposition have a lower risk of cardiovascular disease. The study analyzed data from over 15,000 twins and medical registries, suggesting that genetics may play a role in mitigating the risk of cardiovascular disease.
Researchers found that obstructive sleep apnea (OSA) can cause premature cognitive decline in middle-aged men, including poorer executive functioning and social cognition. The study suggests that OSA itself is sufficient to cause these deficits, rather than being solely attributed to co-morbidities.
New research suggests a way to ward off age-related weight gain by stimulating beige fat cells. Beige fat has thermogenic properties that can reduce blood sugar and fatty acids causing heart disease. The study identifies a specific signaling pathway responsible for suppressing beige fat formation in older mice.
A new UCLA study identifies sex-specific brain signatures associated with obesity in men and women, revealing differences in brain networks related to early life adversity, mental health, and sensory stimulation. The findings suggest the need for tailored interventions based on an individual's sex.
Researchers successfully add purified curcumin to probiotic yogurt, preserving its dissolved form and enhancing its health properties. The study shows that the curcumin inhibits yeast, fungi, and bacteria growth while maintaining the recommended levels of beneficial lactic acid bacteria.
Research shows that higher Body Mass Index (BMI) in the oldest old is associated with a range of health issues. The study also found significant differences between women and men in terms of mental health concerns related to BMI.
Children born to mothers infected with COVID-19 during pregnancy may experience altered growth patterns and increased weight gain in early life, which can lead to a higher risk of obesity, diabetes, and cardiovascular disease. The study highlights the importance of long-term follow-up and prevention strategies for pregnant individuals.
A new class of compounds reduces weight dramatically and lowers blood glucose in lab animals, boosting calorie burn and avoiding nausea. The injectable treatments activate multiple gut hormone receptors, including GLP-1 and PYY, to signal fullness and curb appetite.
Researchers aim to understand the allure of highly processed foods, which make up 58% of US calories. By studying their processing and added ingredients, they hope to identify underlying variables driving consumption.
A team of researchers from Ohio University discovered that CIDEC protein improves vascular and metabolic dysfunction, reducing insulin resistance and lipid levels in high-fat diet-induced mice. The study contributes to understanding the role of the vascular endothelium in regulating systemic metabolism.
Research highlights that intensive behavioral weight loss programs significantly reduce cardiovascular disease and Type 2 diabetes risk factors, which persist for at least five years. Participants who lost weight through such programs had lower risk factors compared to those in less intensive or no weight loss programs.
A new study suggests that age, not weight, should be used to screen for diabetes, capturing the greatest number of people in all racial and ethnic groups. The approach identifies the greatest proportion of adults with prediabetes and diabetes and maximizes equity across racial and ethnic groups.
Exercise training after bariatric surgery alters brain networks associated with food intake and energy regulation. The study found that exercise increased connectivity between the hypothalamus and sensory areas, while decreasing links to the default mode network and salience network.
The study found that vaccination significantly reduces the risk of long COVID, while factors such as being overweight, female, smoker, or over 40 increase the likelihood of developing the condition. Vaccination halves people's risk of developing long Covid
A study by Max-Planck-Gesellschaft researchers found that consuming small amounts of high-fat and high-sugar foods regularly rewires the brain, leading to a preference for these types of food.
A new study found that women with BRCA1 or BRCA2 mutations who are obese may experience higher rates of DNA damage in their breast tissue, which could contribute to breast cancer development. The researchers suggest that weight management and medications like metformin may be important for preventive care.
Researchers developed a small-molecule drug that limits magnesium transport into cellular power plants, resulting in skinny, healthy mice. The findings hold significant implications for preventing cardiometabolic diseases like heart attack and stroke, as well as reducing liver cancer risk.
Richard McIndoe is leading a national research initiative to advance understanding of diabetes and obesity through the National Centers for Metabolic Phenotyping in Live Models of Obesity and Diabetes (MPMOD). The MPMOD initiative provides access to advanced testing services, including bariatric surgery on mice, to enable new insights ...
A new study published in the European Heart Journal shows that using waist-to-height ratio instead of BMI provides a clearer picture of patient outcomes in heart failure. The researchers found that greater adiposity is associated with worse outcomes, including high rates of hospitalization and reduced health-related quality of life.
A new study found that girls born to obese mothers are at higher risk of developing obesity or overweight, with similar BMI and fat mass to their mothers. The association was not seen in boys or daughters from non-obese fathers.
A new study reveals that cross-sector coalitions can create effective policies, systems, and environments for change in addressing early childhood obesity. By bringing together individuals from government, public health, healthcare, and other arenas, coalitions can diffuse knowledge into social and professional networks, leading to inc...
ISB researchers constructed a biological body mass index that offers a more accurate representation of metabolic health. The team found that even with no weight loss, individuals can be getting healthier biologically through positive lifestyle changes.
Cases of Candida auris, a highly contagious fungal infection, rose drastically between 2019 and 2021, with an increase in echinocandin-resistant cases. The findings emphasize the need for improved detection and infection control practices to prevent the spread of C auris.
A recent review article highlights the significant impact of cancer on Hispanic patients and their caregivers, citing communication barriers, financial difficulties, and sociocultural issues. The study estimates 126,000 new cancer cases diagnosed yearly in Hispanics, placing a substantial burden on family members and friends.
Researchers examine how sugar reduction strategies affect new product sales, finding that smaller package sizes perform better than regular sizes. Sugar reductions work better if they do not overemphasize the reduced sugar content in new additions.
Research suggests that high blood caffeine levels are associated with lower weight and body fat, as well as a reduced risk of type 2 diabetes. The study used Mendelian randomisation to explore the potential effects of caffeine on these outcomes.
Researchers found that GIPFA-085, a long-acting GIPRA, acutely inhibited feeding and lowered body weight in diet-induced obese mice. The hormone increased plasma leptin levels and activated satiety neurons, facilitating fat utilization and reducing body weight gain.
UVA researchers discovered a metabolic pathway that can modulate COVID-19 inflammation, lung recovery, and host metabolic health. They suggest a potentially viable therapeutic agent that may be combined with existing anti-viral agents to treat severe COVID-19 in patients with underlying metabolic disease.
A research team from HKUMed developed thyroid hormone (TH)-encapsulated nanoparticles that selectively target adipose tissues, reducing obesity-related metabolic complications and atherosclerosis. The treatment converts 'bad' white fat to 'good' brown fat, burning calories and alleviating hypercholesterolemia.
The prevalence of metabolically healthy obesity (MHO) has been found to increase significantly among U.S. adults over the past two decades, according to a new study published in JAMA Network Open. The research highlights the need for effective strategies to improve metabolic health status and prevent obesity-related complications.
Researchers at Helmholtz Munich discovered a new protein called Cited1 that plays a crucial role in regulating energy homeostasis and sensitivity to satiety hormones. The study found that females are better protected against obesity due to their higher levels of estrogens, which regulate energy metabolism through the hypothalamus.
A new study by Weill Cornell Medicine found that the FDA's mandate to limit opioid-acetaminophen combinations resulted in significant reductions in liver injuries. The mandate, implemented in 2014, limited the dosage of acetaminophen in these drugs, leading to a decline in hospitalizations and acute liver failure cases.
The study found that phenolic extracts from roselle inhibited fat cell formation by 95%, while hydroxycitric acid had no effect. Researchers hope the plant's antioxidants can be used in health food products to manage obesity without side effects.
A 'keto-like' diet, characterized by low carbohydrates and high fat intake, has been linked to higher levels of LDL cholesterol and a twofold increased risk of cardiovascular events. Regular consumption of this diet was associated with an average increase in blood LDL cholesterol levels over 11.8 years.
Lung cancer death rates are projected to decrease overall in the EU and UK in 2023, however, a concerning trend is observed among women in France, Italy, and Spain. Meanwhile, pancreatic cancer death rates are forecasted to rise among women due to continued smoking habits.
A study of nearly 13,000 young US adults found rising diabetes and obesity rates, while hypertension remained stable. The data reveal a high burden of cardiovascular risk factors among this demographic, with Black, Hispanic, and Mexican American individuals disproportionately affected.
A study found that time-restricted feeding improves muscle performance in obese fruit flies by upregulating genes related to glycine production and utilization. This approach may provide a natural alternative therapy for managing obesity-related pathologies.
Preliminary research found that better sleep health was associated with higher rates of attendance at group interval sessions, adherence to caloric intake goals, and improvement in time spent performing moderate-vigorous physical activity. However, the association between sleep health and physical activity was not statistically signifi...
A University of Gothenburg study of over 37,000 men found that being overweight in childhood and young adulthood significantly increases the risk of venous blood clots later in life. The study also suggests that overweight in puberty has a marked impact on future risks of venous thrombi.
Research reveals obesity increases risk of diabetes and hypertension more significantly in women, with weight loss effective in reducing disease risk. However, merely losing weight is insufficient for reducing dyslipidemia in women, highlighting the need for lifestyle improvement guidance and treatment.
The average age of patients requiring anaesthesia increased by 2.3 years over the last decade, with a higher proportion of patients living with overweight and obesity. Surgical cases are becoming more complex, with a decrease in ASA 1 and an increase in ASA 2 and 3 patients.
A new research agenda aims to apply evolutionary principles to modern diseases, emphasizing the role of environmental factors. By studying natural world adaptations, scientists hope to find new ways to prevent and treat disease, such as adopting antimicrobial approaches inspired by hyenas' ability to thrive on carrion.
A new review paper from Mayo Clinic outlines how obesity impacts common tests used to diagnose heart disease, such as ECG, CT scan, MRI, and echocardiogram. The study highlights the need for alternative approaches to prevent weight gain in patients with heart disease.