Articles tagged with Obesity
A new study found that obese individuals with a specific genetic mutation have similar brain activity when shown appetizing foods, whereas overweight individuals without the mutation showed lower response levels. This suggests a link between the MC4R pathway and food cravings.
A study found that people who appreciate weight-related humor tend to hold negative attitudes towards obese individuals, believing in stereotypes such as laziness and unintelligence. In contrast, those who dislike the humor are less likely to believe in these stereotypes.
A study found that individuals low in satiety responsiveness are more likely to experience poor appetite control and overeat, particularly those with a preference for high-fat foods. Increasing almond consumption may help improve satiety responsiveness and increase control over food intake.
Research suggests both high physical activity and less sitting in leisure time are needed to substantially reduce the risk of obesity. Individuals with high physical activity and low leisure time sitting have nearly 4-fold lower odds of becoming obese, according to a new study.
Researchers at Oregon State University found two alternative strategies to counteract the negative impact of obesity on birth control pills. These include a slight increase in pill dose or continuous use without a 'period week', potentially improving pregnancy prevention for obese women.
A Vanderbilt study finds that bacteria produce a therapeutic compound that inhibits weight gain, insulin resistance, and other adverse effects of a high-fat diet in mice. The researchers genetically modified E. coli to produce NAPE, which reduces food intake and weight gain, suggesting a potential new treatment for obesity.
A study published in PLOS ONE found that ancestral exposure to the pesticide methoxychlor can lead to adult-onset diseases like kidney disease and obesity in future generations. The researchers discovered epigenetic changes caused by methoxychlor exposure, which were transmitted through the female line and affected gene expression.
A new study found that obese workers have significantly shorter endurance times when performing workplace tasks compared to their non-obese counterparts. The study also revealed greater declines in task performance among females with obesity, highlighting the need for longer rest breaks and ergonomic redesigns.
Researchers at Vanderbilt University have found a probiotic that prevents obesity by inhibiting weight gain, insulin resistance, and fatty liver in mice. The study suggests manipulating the gut microbiota could treat obesity and other chronic diseases.
A new study by University of Granada researchers shows that consuming probiotics for 30 days can significantly reduce liver fat accumulation in obese rats. This finding is a promising step forward in the fight against Non-Alcoholic Fatty Liver Disease, which is closely linked to obesity and diabetes.
A study from Duke University found that a weight management program significantly reduced depression in nearly half of low-income black women. The 12-month intervention included personalized goals and behavioral changes, which had no direct impact on weight loss or treatment for depression.
Researchers found that obese women struggle with reward-based learning when food is involved, but not when money is the reward. This discovery could lead to new approaches for tackling obesity, focusing on modifying environmental cues rather than food itself.
A study by Yale University researchers found that obese women were impaired in learning associations between food cues and rewards, but normal-weight individuals and men did not show the same impairment. This suggests a specific behavioral intervention targeting food-specific learning impairments may be effective in treating obesity.
Emerging data suggests that being overweight may actually protect patients from cardiovascular mortality, with the risk of total and cardiovascular mortality highest among underweight individuals. Higher body mass index (BMI) has been associated with more favorable outcomes in many acute and chronic disease states.
Researchers found that stress can disrupt the process of fat tissue development, leading to issues with fat storage within cells and in the bloodstream. The study identified a key signaling pathway involving adenosine receptors and stem cell factors that regulates this process.
Research finds physical fitness buffers adverse health effects of prolonged sitting, reducing associations with obesity, metabolic syndrome, and cardiovascular disease. Higher fitness levels are linked to reduced adiposity and improved metabolic measures.
A new study found that nearly half of obese and overweight US firefighters do not receive weight management advice from their healthcare providers. Higher body mass index (BMI) was associated with recommendations to lose weight, while younger firefighters were less likely to receive weight loss advice.
Research finds gut hormone cells, previously thought to contain one hormone, actually secrete six hormones including ghrelin. The discovery sheds light on how weight-loss surgery can cure diabetes, with understanding these hormonal changes crucial for a potential cure.
A study by the University of Granada found that teenagers in Spain, Italy, and Greece have lower cardiorespiratory capacity, strength, and speed-agility than their northern European peers. The researchers also discovered higher levels of total and abdominal fat among southern adolescents, which may be linked to reduced physical activity.
Severe obesity is associated with considerable excess risk for cardiovascular diseases in young Hispanic adults, according to a new study. Young adults with severe obesity are more likely to develop high blood pressure and diabetes, both risk factors for heart disease.
A recent study found that adults with extreme obesity are at a higher risk of dying from cancer and other causes, including heart disease and diabetes. The analysis of pooled data from 20 large studies revealed that people with class III obesity had a significant reduction in life expectancy compared to those with normal weight.
Researchers from Scripps Research Institute have identified two compounds, CoPP and ZnPP, which bind to REV-ERBs and inhibit their activation by heme. These findings suggest that altering the metal ion chemistry of these compounds could be a way to target REV-ERB for treating metabolic disorders.
A study published in PLOS Medicine found that class III obesity (BMI > 40 kg/m2) is linked to higher mortality rates from various diseases. The analysis of 20 prospective studies revealed a substantially increased risk of death among class III obese individuals, particularly those with heart disease and cancer.
Researchers found a 57% decrease in wound complications when sutured incisions were used compared to staple closure. Suturing takes 9 minutes longer to complete than stapling, but has a clear benefit for women.
Research finds that excess belly fat, low physical activity, and underweight status increase COPD risk. People with larger waist circumference have a 72% higher chance of developing COPD.
A recent study published in Cell Press found that high levels of a molecule called heme oxygenase-1 (HO-1) are linked to poor metabolic health and an increased risk of type 2 diabetes in obese humans.
Half of US adults suffer from at least one chronic condition, with a quarter having two or more. The report highlights the need for coordinated action to reduce the chronic disease burden, including promoting health and healthy behaviors, effective prevention services, and stronger links between healthcare and community services.
A recent study published in PLOS ONE reveals that urbanisation and westernization are linked to rising obesity rates among Nigerian women, particularly those with higher socio-economic status. The findings highlight the need to address both malnutrition and obesity as major public health concerns in Nigeria.
A*STAR scientists discovered that obese individuals lack a crucial protein essential for regulating blood glucose levels, increasing their risk of developing diabetes. The protein, NUCKS, is the first molecular link found between obesity and diabetes, opening up new areas of research for potential treatments.
Researchers at The Miriam Hospital developed an app to reduce sedentary behavior in obese individuals. The app, B-Mobile, uses automated prompts and feedback to encourage short breaks and increase physical activity, resulting in reduced sedentary time and improved health outcomes.
A large-scale study found that young women with Polycystic Ovary Syndrome (PCOS) have a higher incidence and prevalence of type 2 diabetes, even if not overweight. Obesity is not a significant trigger for type 2 diabetes in PCOS patients.
A study published in the Journal of Clinical Investigation found that engineered bacteria can prevent weight gain in mice by producing a compound called NAPE, which signals the brain to stop eating. Mice fed high-fat food with NAPE-producing bacteria exhibited limited weight gain and associated symptoms.
A new study by Gelesis found that its hydrogel capsule, Gelesis100, led to significant weight loss in overweight and obese individuals, particularly those with impaired fasting blood glucose levels. The three-month trial showed an average weight loss of 6.1%, 4.5%, and 4.1% for the active, high-dose, and placebo groups respectively.
A new study shows that patients who undergo gastric bypass surgery lose significant amounts of bone density, even after their weight stabilizes. Bone health may need to be closely monitored in these patients to prevent fractures and osteoporosis.
A multicenter study found that liraglutide, a diabetes drug, reduced weight and improved cardiovascular risk factors such as high blood pressure and cholesterol levels. The results showed significant improvements in weight loss and lipid profiles, suggesting a potential lower risk of heart disease.
A study of over 39,000 respondents found that obese individuals report higher satisfaction with weight loss surgery and medication compared to self-modification methods. The findings suggest that these approaches should be considered integral parts of weight management for eligible patients.
A study published in Cell Metabolism reveals that free radical molecules contribute to the development of type 2 diabetes, obesity, and fatty liver disease by inactivating protein tyrosine phosphatases. This inactivation leads to a cascade of events promoting disease progression.
Researchers found changes in gut microbiota composition among people with Type 2 diabetes or obesity compared to healthy individuals. The study identified associations between specific bacterial species and metabolic variables such as BMI, hemoglobin A1c, and waist circumference.
A new study suggests that individuals who are overweight, obese, or former smokers are more likely to follow recommended statin therapy for high cholesterol. Nonadherence to prescribed medication can lead to a significant risk of cardiovascular events, with studies indicating that nonadherence rates as high as 46% have been observed.
A study found that vitamin D treatment improved glucose tolerance and insulin sensitivity in obese rats, reducing food intake and weight. The findings suggest a potential role of vitamin D in the onset of obesity and Type 2 diabetes through its action in the brain.
A new study finds that diabetes drug liraglutide, when combined with diet and exercise, leads to significant weight loss of up to 18.7 pounds and reversal of prediabetes in nearly 70% of participants. The medication also delays the development of type 2 diabetes by three times.
A new study found that blast traumatic brain injury may be linked to pituitary dysfunction, particularly in overweight patients. The study suggests that treating hormone deficiencies may help alleviate symptoms in veterans with this condition.
A new study from China finds that obese pregnant women who adhere to an intensive nutritional and exercise program starting in the first trimester gain less weight and have fewer pregnancy complications compared to peers who receive standard prenatal care. The results show a significant reduction in gestational diabetes, pre-eclampsia,...
A long-term follow-up study found that bariatric surgery resulted in more frequent diabetes remission and fewer complications compared to usual care. The study showed a significant decrease in microvascular and macrovascular complications.
Researchers reconstituted VcINDY into liposomes to analyze its properties as a transporter, providing insights into the cellular level functionality of SLC13 transporters. This study paves the way for targeting these transporters to combat metabolic disease and obesity.
A study found that overweight children with a common gene mutation are more likely to have elevated liver values. The research highlights the importance of healthy lifestyle habits from an early age, particularly for children carrying the risk gene.
Research has linked kisspeptin signaling to increased weight gain and glucose intolerance in mice lacking the pathway. This study found that reduced metabolism and decreased energy led to excess weight gain, not increased food consumption. The findings have potential for treating human obesity.
Research published in Nature Communications reveals a faulty electrical switch in the uterus of overweight women, causing irregular contractions and increasing the risk of caesarean sections. This breakthrough discovery sheds light on the mechanism behind labour complications in overweight women, paving the way for potential treatments.
Research in southern Ontario found that adults living in more walkable neighborhoods experienced a lower risk of developing diabetes over a 10-year period. The most walkable neighborhoods had the lowest incidence of obesity, overweight and diabetes.
Researchers discovered that retinoic acid stimulates brown fat to increase basal energy metabolism, preventing obesity-related diabetes complications. The study suggests a potential therapeutic approach for treating type 2 diabetes through the use of retinoids.
A soft-drink tax has been found to be an effective way to reduce consumption and lead to significant weight losses. The study estimated that middle-income heavy consumers would lose up to 3.64 kg, making it a cost-effective solution for obesity prevention.
Researchers found a correlation between affluence and obesity rates, with women typically having higher levels of obesity than men in developing countries. However, in the Western world, male obesity often exceeds female obesity, suggesting an alternative cause may be at play.
Researchers develop computer model to speed up search for compound that activates FFA4 protein, a key player in appetite regulation and glucose uptake. The model aims to identify molecules that bind to the protein, potentially leading to a new obesity treatment.
A new study from the University of Pennsylvania School of Medicine reveals that weight loss is the single most important factor for improving cardiovascular health in obese obstructive sleep apnea (OSA) patients. Weight loss alone significantly reduced inflammation, insulin resistance, dyslipidemia, and high blood pressure.
A recent EULAR study found that obese patients with rheumatoid arthritis (RA) have higher disease activity scores than non-obese patients, irrespective of their disease stage. This suggests that treatment to target protocols may result in obese patients being treated more aggressively than non-obese patients.
A long-term follow-up of obese patients with type 2 diabetes shows that bariatric surgery leads to more frequent diabetes remission. The study found that bariatric surgery results in a lower incidence of microvascular and macrovascular complications compared to usual care.
Researchers discovered a new hormone called Metrnl that activates brown and beige fat, leading to improved metabolic health in obese mice. Interleukin-4 signaling also played a crucial role in stimulating beige fat formation.
Researchers at the University of Texas Health Science Center at San Antonio have identified a protein called Grb10 as the on-off switch for converting unhealthy white fat into beige fat, a process that increases energy expenditure and reduces obesity. The finding could lead to the development of novel diabetes and obesity drugs.
Research reveals a key role for HIF-1 alpha in insulin resistance, type 2 diabetes, and obesity-related inflammation. The protein's inhibition shows promise as a potential treatment for these conditions, including its application to cancer.
A study associates depression with atypical features, including increased appetite, with obesity. The researchers emphasize the importance of screening for these atypical features in individuals with depression and recommend dietary measures during depressive episodes.