Articles tagged with Obesity
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A new delirium severity score helps predict hospital outcomes in patients with delirium. The Confusion Assessment Method (CAM) scoring system is validated for predicting adverse outcomes, including prolonged hospital stay and functional decline. Additionally, a US survey shows that obesity contributes to the dramatic increase in diabet...
Researchers identified a protein, nicotinamide N-methyltransferase (NNMT), that can be altered to increase energy expenditures. Reducing NNMT levels in fat and liver cells dramatically reduces obesity and diabetes development in mice.
Research identifies cellular signaling dysfunction causing brown fat cells to lose blood vessels and mitochondria, leading to energy production failure and increased risk of metabolic disorders.
New research by Andrew Stokes suggests that excess weight in the US substantially increases mortality risk, contrary to previous findings. Using individuals' highest BMI in life to predict mortality rates, Stokes found a 33% attributable risk for overweight and obesity.
A new study by Monash University has shown that gastric banding can lead to remission of diabetes in people who are overweight but not obese. The research, published in The Lancet Diabetes and Endocrinology, found that weight loss surgery significantly improved the condition in over half of participants.
A UCLA psychology study reveals that a diet high in processed foods leads to weight gain, fatigue, and cognitive impairments. The research suggests that junk food diets, not lack of exercise or discipline, are responsible for obesity and related health issues.
A new study found that cigarette smoking among obese women interferes with their ability to taste fats and sweets, making them more likely to consume high-calorie foods. The study suggests that this may contribute to the consumption of more calories, exacerbating weight-related health issues.
A new study from Beth Israel Deaconess Medical Center suggests that upwards of half of high-risk drinkers experience improved behavior post-weight loss surgery. Seven percent of patients who did not show signs of high-risk drinking at baseline later developed the condition, highlighting the need for better screening and monitoring.
A new study by Florida State University Associate Professor Arturo Figueroa found that watermelon extract significantly reduced blood pressure in overweight individuals at rest and under stress. The study showed improvements in aortic blood pressure and cardiac stress while exposed to cold temperatures.
A new NIH study reveals that obesity primes the colon for cancer, with frequent exercise and calorie control shown to lower the risk. The research suggests that molecular signals in the gut lead to cancer progression in obese mice, highlighting the importance of a healthy lifestyle in preventing colorectal cancer.
Bariatric surgery patients report better quality of life, reduced need for cardiovascular medications, and improved blood sugar control without insulin or most diabetic medications. The STAMPEDE trial shows gastric bypass surgery is more effective than medical therapy in treating type 2 diabetes in obese patients.
Gastric bypass and sleeve gastrectomy surgeries show significant improvement in glycemic control, weight loss, and cardiovascular risk factors compared to intensive medical therapy. Patients undergoing surgery also experience reduced reliance on medications and improved quality of life measures.
Researchers found a strong link between the AMY1 gene and obesity, with individuals having fewer copies of the gene at higher risk. This discovery highlights the importance of tailoring dietary advice based on an individual's digestive system.
A recent study published in the Journal of Epidemiology and Public Health found that being underweight increases the risk of death for both adults and fetuses. Adults with a BMI under 18.5 are 1.8 times more likely to die than those with a normal BMI, while obesity is associated with a 1.2-1.3 times higher risk of mortality.
A comprehensive review of bariatric surgery data shows that death rates are reduced by 40% and heart attacks by half compared to non-surgical obese patients. Obesity is a significant health issue worldwide, associated with heart disease, type 2 diabetes, and shorter life expectancy.
Researchers found Gen X has significantly poorer health status, higher obesity rates, and no difference in physical activity compared to Baby Boomers. The study suggests drastic lifestyle changes, such as increased sedentary behavior and access to unhealthy food, contribute to earlier development of age-related conditions.
A nationwide study found that overweight and obese teenagers in Israel had no significant improvement in survival rate over four decades, compared to normal-weight peers. Mortality rates among these teens were higher than those observed in the 1960s and 1970s.
The journal Gynecologic Oncology highlights the impact of obesity on gynecologic cancer prevention, treatment, and survivorship in obese women. Research shows that 72% of US women have a BMI of ≥ 25 kg/m2, making it challenging to convince patients of behavioral change.
A retrospective cohort study of 7,431,858 patients found that bariatric surgery significantly reduces the risk of endometrial cancer. Bariatric surgery can lead to normal hormone levels, decreased inflammation, and improved overall health.
A recent study found that obese women may require a higher or adjusted dose of GnRH antagonist medication for successful IVF egg harvesting due to faster clearance rates and rebound hormone responses. This could improve fertility treatment outcomes for overweight and obese women.
A recent study found that high sodium intake in teenagers can lead to faster cell aging, with overweight and obese teens showing the most significant effects. Researchers analyzed data from 766 people aged 14-18 and discovered that those who consumed more salt had shorter telomeres, which protect chromosomes from damage.
A 16-week healthy lifestyle program taught in American Sign Language resulted in moderate improvements in weight and physical activity among deaf adults. The study, led by Dr. Steven Barnett, found that 58.3% of participants lost at least 5% of their baseline weight.
A study of over 37,000 men and women found that eating fried foods four times a week had twice the impact on body mass index (BMI) for those with the highest genetic risk scores. Genetic variants associated with BMI and obesity also interacted with fried food consumption to influence adiposity.
A new study from Harvard School of Public Health found that regular consumption of fried foods increases the risk of obesity in people with a genetic predisposition to obesity. The study analyzed data from three US cohort studies and found that high intakes of fried food exacerbated the deleterious effects of genetic variants associate...
A study of obese orthopedic trauma patients found higher rates of complications and increased healthcare costs, but surprisingly lower injury severity scores compared to non-obese counterparts. The research revealed that obese patients required longer hospital stays and more intensive care unit admissions.
Research suggests that people exposed to more takeaway food outlets are more likely to consume these foods and be obese. The study found a significant dose-response relationship between takeaway outlet exposure and both diet and body mass index.
Researchers identified DNA methylation changes in the HIF3A gene that correlate with BMI and increase the risk of diseases like diabetes. The study suggests a new potential target for treating obesity-related health issues.
The BRCA1 gene is expressed in skeletal muscle cells and plays a critical role in fat storage, insulin response, and mitochondrial function. Mutations in the BRCA1 gene may increase the risk of metabolic diseases like obesity and type 2 diabetes.
A recent study discovered that IRX3 controls body mass and regulates body composition, with obesity-associated FTO introns interacting with IRX3. Mice without the IRX3 gene were significantly leaner due to reduced fat and improved glucose processing.
A new UCL study suggests that more educated consumers in middle- and low-income countries make better food choices that mitigate the negative effects of rising wealth on obesity levels. The study found a 14-19% lower risk of obesity among women with secondary or higher education, compared to those with less education.
A study identifies a key role for RBP4 in insulin resistance and inflammation of fat tissue, leading to an increased risk of diabetes. Researchers found that elevated RBP4 levels activate immune cells, triggering chronic inflammation and metabolic dysfunction.
A recent analysis found that frequent experiences of racism were associated with a higher risk of obesity among African American women. Women who reported consistently high experiences of racism over a 12-year period were 69% more likely to become obese compared to those in the lowest category.
A randomized controlled trial found that moderate-intensity supervised exercise reduces excessive gestational weight gain and the risk of associated illnesses such as hypertension and gestational diabetes. The benefits are greatest in women of normal weight, but even overweight or obese women can benefit from exercise.
Research finds that living in a socioeconomically deprived region increases the risk of diabetes and obesity, regardless of individual social status. The study analyzed data from over 33,000 people and found significant correlations between regional deprivation and type 2 diabetes and obesity rates.
Researchers found that women who are obese at age 20 are twice as likely to develop MS later in life. Additionally, those who used hormonal contraceptives for at least three months were 35% more likely to develop MS compared to non-users, highlighting a potential contributing factor to the rise in MS cases among women.
A study by Montreal researchers found a significant link between exposure to persistent organic pollutants (POPs) and certain metabolic complications of obesity. The study, published in the Journal of Clinical Endocrinology & Metabolism, suggests that metabolically healthy but obese individuals have lower circulating levels of POPs tha...
A single molecular switch governs production of protective mucus lining intestinal walls, which can be breached by failure of immune system, leading to diseases like inflammatory bowel disorders and metabolic conditions.
Regular exercise and surgical removal of belly fat can improve cognition in obese, diabetic mice by reducing inflammation in the brain's hippocampus. Obesity and diabetes increase the risk of mild cognitive impairment and Alzheimer's disease.
A new analysis has found that babies born by caesarean section are more likely to be overweight or obese as adults. The odds of being overweight or obese are 26 per cent higher for adults born by caesarean section than those born by vaginal delivery, according to the study.
Overweight pregnant women who believe they are 'eating for two' tend to experience excessive weight gain, while those with a goal-oriented approach and healthy habits gain appropriate weight. Monitoring weight gain during pregnancy can help prevent future complications and obesity.
Overweight children exposed to higher levels of perfluorinated chemicals show early signs of metabolic syndrome, a cluster of risk factors for heart disease, stroke, and diabetes. The study highlights the potential public health hazard of these industrial chemicals.
A new study published in PLOS ONE found that the Body Shape Index (ABSI) is a strong indicator of mortality hazard, surpassing traditional measures like Body Mass Index (BMI). The research analyzed data from over 7,000 adults and showed that ABSI was closely linked to increased death rates.
A study found that feeding cats smaller meals more frequently increased their physical activity, particularly when anticipating meal times. This approach can be a practical solution for pet owners to manage feline obesity and diabetes.
A study by Johns Hopkins researchers found that primary care doctors' negative attitudes towards their obese patients can hinder weight loss success. Only 14% of those who felt judged and discussed weight loss with their doctor lost 10% or more of their body weight.
A recent study found that Samoa's adult population is almost three-quarters obese, with type 2 diabetes rates over one in five. The island's unique genetic profile and environmental factors are being investigated to understand the causes of this obesity crisis. This phenomenon may serve as a harbinger for global health difficulties.
Recent research highlights the critical role of gut flora in diabetes and obesity, with studies suggesting a strong connection between the two. The CommHERE consortium, comprising nine European institutions, has brought together leading experts to discuss their findings on the impact of gut microbiota on metabolic diseases.
A new study by UC Berkeley researchers found a correlation between northern latitude and higher levels of obesity-linked bacteria in the gut. The analysis of over 1,000 people from around the world revealed that those living in colder regions had more Firmicutes and less Bacteroidetes in their gut microbiomes.
A recent study published in PLOS Medicine suggests that type 2 diabetes may not be directly linked to substantial weight gain over time. Instead, researchers identified distinct patterns of obesity development, including stable overweight individuals and those who experience continuous weight gain before diagnosis. The findings highlig...
A study by researchers at SUNY Downstate Health Science University found that being overweight is associated with lower levels of N-acetyl-aspartate (NAA) in the hippocampus, a part of the brain involved in memory and emotions. The effect was independent of age, sex, and psychiatric diagnoses.
An international study found a strong association between household device ownership and increased rates of obesity and type 2 diabetes in lower and middle income countries. The prevalence of these conditions rose with the number of devices owned, highlighting the need for health interventions to mitigate the effects of modernization.
Researchers at Beth Israel Deaconess Medical Center have identified the paraventricular nucleus as a key player in regulating hunger. By mapping neural circuits and manipulating upstream neurons, the team discovered that this brain region communicates with AgRP neurons to drive intense motivation for food.
A Michigan State University study found that obese men are more likely to have colorectal polyps, precancerous growths linked to colon cancer. The research showed a significant association between elevated leptin levels, higher body mass index, and larger waistlines with an increased risk of having these polyps.
A new study reveals that adolescents consuming excessive salt are more likely to develop obesity and chronic inflammation. The research, published in the journal Pediatrics, found a significant correlation between sodium intake and fatness, even when calories were controlled for.
A study published in the Bulletin of the World Health Organization suggests that governments can slow and reverse the growing obesity epidemic by regulating fast food consumption. The study found that countries with stricter market regulations had lower increases in fast food transactions per capita, indicating a potential link between...
Bariatric surgery is the most effective treatment for both obesity and type 2 diabetes, offering substantial benefits in terms of weight loss, metabolic status, and quality of life. In people with type 2 diabetes, bariatric surgery can reverse complications and improve end-organ health, including pancreatic, renal, retinal, peripheral ...
Researchers discovered that valproic acid activates AMPK, which reduces fat accumulation in the liver and lowers blood sugar levels in obese mice. Treated mice showed decreased blood sugar levels and a stabilization of weight.
A recent study found that consuming certain probiotics from the Lactobacillus rhamnosus family can lead to significant weight loss in women, with an average loss of 4.4 kg over 12 weeks. The probiotics also helped maintain weight loss over a longer period and reduced appetite-regulating hormone leptin levels.
A new study found that labeling obesity as a disease can lead to less importance on health-focused dieting, greater body satisfaction, and unhealthier food choices among obese individuals. The findings suggest that the messages individuals hear about obesity have self-regulatory consequences.
A study by the University of Georgia found that people with impulsive personalities are more likely to experience food addiction, a compulsive pattern of eating similar to drug addiction. This is associated with obesity, highlighting the need for new treatments to address compulsive eating habits.
A recent study published in Liver Transplantation found that obese liver transplant recipients with diabetes experienced higher morbidity rates due to post-transplant complications, particularly diabetes and metabolic syndrome. Despite this, obesity did not negatively affect survival rates.