Researchers at Loyola University Chicago Stritch School of Medicine identified a way to assess UTI risk in women after pelvic-floor surgery. The study found that certain urinary bacteria and antimicrobial peptides can identify women at increased risk, suggesting a potential method for improved prevention and treatment strategies.
Researchers explore applying additive manufacturing techniques to aero engine market, reducing environmental costs and fuel consumption. The project aims to demonstrate the potential of metal components laser-based additive manufacturing to contribute to the reduction of air transport environmental impact.
UTHealth School of Biomedical Informatics has received $7.3 million in grants to develop health information technology solutions. Researchers are working on projects to mine medical data, make electronic health records user-friendly, and improve patient safety.
A new study by Georgia State University and CDC finds that US taxpayers spend $45 billion on Medicare, $39.9 billion on Medicaid, and $23.8 billion on other government-sponsored insurance programs each year due to smoking-related diseases. Smoking accounts for 8.7% of annual healthcare spending in the US.
Scientists at IRB Barcelona have identified two derivatives of borrelidin that completely remove the parasite load from mice and confer immunological memory to fight future infections. These compounds act on the protein production machinery of the parasite, making them efficient in all phases of infection.
NOAA and partners have released detailed sonar maps and images of the historic SS City of Rio de Janeiro, a San Francisco shipwreck that sank in 1901, killing 128 people. The wreck was located using cutting-edge technology in the Gulf of the Farallones National Marine Sanctuary.
A 13-year decline in vegetation in the eastern and southeastern Amazon has been linked to a decade-long rainfall decline in the region. The study used new satellite instruments to measure greenness and found a 0.8% decline in the Amazon, affecting over half the continental United States' area.
Scientists have developed a stretchable electronic skin that can detect pressure, location, intensity, and direction. This innovation could be used in prosthetic limbs, robotic skins, and rehabilitation devices.
Researchers found that trastuzumab benefits HER2-positive breast cancer patients do not depend on the number of tumor-infiltrating lymphocytes (S-TILs) in their tumors. The study, which measured S-TILs at diagnosis in over 1,000 patients, showed improved recurrence-free survival when chemotherapy alone was used.
Researchers at UC San Diego have developed a more efficient method to trap light by harnessing bound states in the continuum. This innovation addresses the major challenge of trapping and utilizing light for optical computing circuits.
Researchers have identified a novel therapeutic approach using gamma secretase inhibitors (GSI) to inhibit Notch and block critical genes involved in tumor growth. The study suggests that GSI may optimize existing endocrine therapies and overcome resistance to cancer drugs.
A study published in Annals of Emergency Medicine found that Internet searches on a regional medical website can predict emergency department visits with an error rate of 4.8%. This correlation was strongest for the entire county, suggesting that Internet data may be used to forecast emergency department demand.
Researchers have identified bacterial genes that help UTIs spread, providing a potential new target for treating UTIs. The study reveals the specific genes expressed by E. coli bacteria in human urinary tract infections, which can be attacked to promote survival of the bacteria.
A genetic study found shared mutations between house dust mite populations in the US and South Asia, indicating migration across continents. The discovery highlights the potential for these tiny creatures to travel long distances and establish new populations.
A team of researchers at Tel Aviv Sourasky Medical Center developed an Induced Sputum (IS) technique to assess the effect of pollution on urban asthmatic children. The study found that IS is a more physiologically sensitive biomonitoring method than environmental sampling stations, detecting hazardous particles like mercury in the lungs.
A study published in JAMA Dermatology analyzed data from nine population-based studies and found no overall association between eczema and short stature. However, a small group of children with severe eczema who experienced sleep disturbances showed potentially reversible growth impairment.
A new study published in Marketing Science reveals that ads can still convey their main message despite brief and blurred exposure to consumers. The study found that the color of central objects in ads plays a crucial role in rapid perception and 'ad cut through' under these conditions.
Researchers at UC Berkeley have developed a new organic optoelectronic sensor that can accurately measure blood-oxygen levels and is thin, flexible, and disposable. The device uses red and green light to detect changes in oxygen saturation levels, making it potentially cheaper and more convenient than conventional pulse oximeters.
Typhoon Hagupit brought heavy rainfall to the Philippines, with NASA's Terra satellite capturing a picture of the storm. Rainfall totals reached over 450 mm in eastern Philippines and over 477 mm in the open waters of the Philippine Sea.
Researchers at Imperial College London discovered a possible way to identify which patients should avoid using COX-2 inhibitors, a type of non-steroidal anti-inflammatory drug (NSAID), due to increased heart attack risk. The study found that COX-2 inhibitors raise levels of ADMA, an independent risk factor for cardiovascular disease.
A new procedure combining surgery to remove part of the pancreas and islet cell transplantation appears safe and effective for alleviating pain from severe chronic pancreatitis. Eight out of nine patients who underwent this procedure were able to discontinue insulin use, with two requiring no insulin at all.
Researchers develop a propionate supplement that targets gut hormone release, leading to reduced food intake and fat distribution. The study shows significant weight loss and fat reduction in participants taking the supplement, with minimal side effects.
A University of Georgia study found that pregnant women who gain less than 20 pounds are more likely to have male fetuses with lower survival rates. The research analyzed over 46 million pregnancies and suggests that weight gain may play a crucial role in determining fetal sex.
A phase III clinical trial found that treatment with progesterone after traumatic brain injury provided no significant benefits compared to placebo. The study involved 49 trauma centers and 882 patients, but was stopped early due to safety concerns.
The German Breast Group study found nab-paclitaxel (ABRAXANE) demonstrates significant benefit for patients with early high-risk breast cancer when compared to conventional solvent-based paclitaxel. Nab-paclitaxel achieved a 9% absolute improvement in pathological complete response rate, outperforming traditional chemotherapy.
A team of Penn State engineering students designed workstations that allow users to share space while maintaining their own work areas. The researchers used simulations to determine optimal table shapes and sizes for accommodating groups of different sizes, ultimately publishing their findings in Applied Ergonomics.
A treatment pioneered at the University of Pittsburgh Center for Vaccine Research is far more effective than traditional antibiotics in inhibiting the growth of drug-resistant bacteria. The new drug, called engineered cationic antimicrobial peptides (eCAPs), inhibited growth in about 90% of test bacterial strains.
A recent study published in PLOS ONE found a significant link between prenatal exposure to di-n-butyl phthalate (DnBP) and di-isobutyl phthalate (DiBP) and substantial drops in child IQ scores. Children exposed during pregnancy to these chemicals had IQ scores on average six points lower than those exposed at lower levels.
A multinational trial of progesterone in severe TBI patients found no clinical benefits, with no difference in outcomes or mortality rates between groups. The study highlights the difficulty in demonstrating efficacy for this complex disease, and emphasizes the need for further research to find effective treatments.
A new study shows racial disparities in Medicare Advantage persist across the US, except in Western states, where control of key health measures is higher for black seniors. In contrast, Eastern and Midwestern states show significant gaps between white and black seniors.
Researchers at CWRU developed a 24-week home-based exercise program using customized pamphlets to help people with MS stay physically active. The program showed promise in improving physical function and reducing symptom severity, particularly for women with relapsing-remitting MS.
A new study finds that support from friends generally influences the effects of peer victimization on maladjustment, differing depending on the form of victimization and relationship with peers. Teenagers who suffered relational victimization experienced lower feelings of depression with more supportive friendships.
Professor Christian Hertweck has been awarded the prestigious Leibniz Prize for his groundbreaking research on biologically active compounds. His team discovered that endosymbiotic bacteria living within fungal cells are responsible for producing toxins, challenging the long-held belief that fungi produce these toxins.
Researchers found that givers tend to choose specific gift cards that recipients may not prefer. To avoid this, consider focusing on what recipients want rather than who they are. This approach can lead to more versatile gift cards being chosen, resulting in better redemption rates.
Researchers revised a mathematical description of particle interactions, considering two forces unified under extreme conditions like the Large Hadron Collider. They simplified one description of elementary particles' behavior, predicting specific events that future experiments should observe.
Researchers at University of Strathclyde and City University of New York have developed a screening method to accurately predict how peptides can combine to form stable gels. This breakthrough simplifies the discovery of functional gels for various applications, including food, cosmetics, and biomedicine.
A new study published in Neurology found that pregabalin is not effective in controlling the pain associated with lumbar spinal stenosis. The most common type of chronic lower back pain in older adults, this condition affects millions worldwide and often leads to surgery or stronger pain medications.
A study published in PLOS ONE estimates that nearly 269,000 tons of plastic pollution are floating in the world's oceans, with an additional 5 trillion microplastic particles present. This research was conducted over six years across five sub-tropical gyres and coastal regions.
The study finds that laser-induced graphene (LIG) has a unique structure with five- and seven-atom rings, which can store charges and make it suitable for supercapacitors. Researchers developed a scalable one-step process to create LIG in detailed patterns.
Researchers developed a nanocrystalline high-entropy alloy with low density and high strength, surpassing titanium alloys. The alloy's unique properties make it suitable for various applications such as vehicles or prosthetic devices.
A new study published in the European Respiratory Journal suggests that toddlers who share a bed with their parents are more likely to develop asthma in later childhood. Researchers found an association between bed-sharing at two years old and increased wheezing symptoms in early childhood.
A University of Colorado Cancer Center study reveals that triple-negative breast cancer cells process tryptophan to promote survival while detached, allowing them to metastasize. The kynurenine pathway, specifically the enzyme TDO2, plays a key role in degrading tryptophan and evading anoikis.
A study published in the RAND Journal of Economics found that price discrimination by ISPs can lead to increased web congestion, as consumers adjust their behavior to take advantage of faster services. The researchers argue that relaxing net neutrality rules would ultimately benefit ISPs at the expense of consumers.
A study by USCB researchers determined that building an audience and engaging it during crowdfunding is crucial for success. The most important networks were those that were scalable, such as Twitter and email, which helped bring people to the projects.
Researchers at the University of Manchester discovered a molecular 'tag team' controlling cell division in yeast cells. This relay system ensures proper regulation of mitotic exit, a critical step in preventing abnormal growth and cancer development.
A study using fMRI found that fructose triggers greater activation in the nucleus accumbens and higher ratings of hunger compared to glucose, suggesting it may promote overeating. The findings have important public health implications for a society with high-sugar foods and tempting stimuli.
Research from the University of Cambridge suggests that a simple supplement could reduce heart disease risk in individuals born with low birth weight. The study found that a molecule called CoQ prevented cells in the aorta from ageing prematurely, which can lead to heart disease.
The article highlights the persistent health gap between whites and blacks, despite improvements in care access. Effective strategies for closing this gap include reporting clinical performance data by race, offering tailored interventions, and creating risk-adjusted scores.
Researchers have identified the first definite horned dinosaur species from the Early Cretaceous period in North America, known as Aquilops americanus. This discovery sheds light on the biogeography of neoceratopsian dinosaurs and suggests a late Early Cretaceous intercontinental migratory event between Asia and North America.
A new study by University of Notre Dame researchers found that the most abundant protein in the Ebola virus, VP40, mediates replication and interacts with human cell lipids. This discovery may lead to novel therapeutics for combating Ebola.
A phase II trial found that a combination of bortezomib and fulvestrant delayed disease progression in post-menopausal women with hormone-receptor-positive metastatic breast cancer. The study showed a doubled rate of survival at 12 months compared to fulvestrant alone.
A study published in Liver Transplantation found that liver transplant recipients with limited literacy struggle to understand and adhere to their medication regimens, resulting in higher rates of organ rejection and graft loss. The study suggests that improving treatment knowledge and regimen use can reduce post-transplant re-hospital...
Researchers at the University of Missouri found evidence suggesting testosterone contributes to colon cancer tumor growth. Higher levels of testosterone in post-menopausal women may be associated with increased colon cancer risk.
Scientists have developed a mathematical theory based on roundworm foraging that predicts how animals decide to switch from localized to very broad searching. The theory could explain animal behavior in a more unified way, including attention deficit hyperactivity disorder (ADHD) and extraterrestrial behavior.
A study analyzing ancient polar ice cores reveals a significant increase in atmospheric nitrous oxide concentrations from 16,000 to 10,000 years ago. The rise was caused by changes in environmental conditions, contributing to the warming at the end of the ice age and melting of large ice sheets.
A study of nearly 15,000 middle-aged men and women found that those with the highest waist-to-hip ratio were twice as likely to experience sudden cardiac death as those with a normal ratio. The risk was strongly associated with central obesity, particularly around the midriff, which is thought to contribute to inflammation.
Researchers discovered that enzymes dissipate heat by rapidly accelerating immediately after a reaction, generating a pressure wave called a chemoacoustic wave. This finding explains how proteins cope with the immense heat generated during enzyme reactions without breaking apart.
Researchers have developed a new type of smart window that can respond to heat cues, blocking unwanted heat from entering buildings while still allowing natural light to pass. The new design uses microscopic soft beads suspended in a liquid and has shown promise in reducing energy consumption on hot days.
Researchers find that embryonic stem cells can modify their metabolism to keep their entire genome accessible, allowing them to renew themselves. This discovery could lead to breakthroughs in regenerative medicine and a better understanding of cancer.
Scientists at the University of Pittsburgh School of Medicine have made a groundbreaking discovery in treating corneal injuries by using stem cells from a patient's own eye. The study found that these cells can regenerate healthy corneal tissue, clearing the cloudy surface and restoring vision.
Physicists at Goethe University Frankfurt have used the COLTRIMS reaction microscope to demonstrate that the structure of the helium-3 molecule is a 'cloud' rather than a solid structure. The results resolve a long-standing dispute in theoretical physics and show that all possible configurations are equally probable.
A new fossil analysis reveals that Vintana sertich was a badger-sized, herbivorous animal with keen senses of smell and vision. The study sheds light on the diversity of Mesozoic mammals and their paleoecology.
Researchers found that alcohol interferes with the body's natural sleep-regulating mechanism, altering sleep patterns and causing disrupted sleep. The study suggests that drinking alcohol to fall asleep can have negative consequences on sleep quality and overall health.
Researchers suggest that peroxisome proliferator-activated receptor (PPAR) agonists may be effective in treating alcohol dependence. The study found that PPARα or PPARγ agonists, such as fenofibrate, reduced alcohol intake and preference in mice, indicating potential for repurposing these drugs for human treatment.
A new study published in Neurology found that people with sleep apnea or reduced deep sleep are more likely to have brain abnormalities associated with dementia. The study also discovered that those who spent less time in slow wave sleep had loss of brain cells, a risk factor for Alzheimer's disease.
Scientists have discovered that dragonflies employ a sophisticated system of movement and prediction to catch their prey. By analyzing the intricate movements of their heads and bodies, researchers found that dragonflies use internal models to guide their behavior and anticipate the movements of their prey.
Researchers at UT Southwestern Medical Center found that enterohemorrhagic E. coli (EHEC) uses Bacteroides thetaiotaomicron to worsen its own infection by stealing scarce resources from other gut bacteria. This discovery opens up new avenues for understanding how microbiota composition impacts infection outcomes.
Researchers at CWRU School of Medicine discovered the mechanism behind enzyme Lecithin: retinol acyltransferase (LRAT) storing vitamin A, essential for vision. The study reveals that modifying LRAT's enzymatic activity can be used to transport small molecule drugs to the eye, reducing systemic side effects.
Researchers found lower concentrations of lead and other heavy metals in moss samples from the oil sands area, contrary to current scientific knowledge. The study, published in Environmental Science and Technology, suggests that other factors may be affecting lead pollution levels.
Research suggests that saving previous information helps free up cognitive resources, improving memory for new information. By 'offloading' old data, individuals can allocate mental resources to learn and remember new material.
Scientists at the University of Exeter have developed a new method to diagnose epilepsy using mathematical modeling and brain electrical activity analysis. This approach reveals subtle differences in brain network properties that enhance susceptibility to seizures in people with idiopathic generalized epilepsies.
A study published in JAMA found that many breast cancer surgery patients do not receive shorter radiation treatment, despite guidelines recommending it for selected patients. Hypofractionated WBI has been shown to be equally effective as conventional WBI but with lower health care costs and reduced treatment burden.
Researchers found that microglia cells in autism brains are perpetually activated and their genes for inflammation responses are turned on. The study is the largest so far of gene expression in autism brains, analyzing data from 104 brain samples.
Researchers will use techniques like molecular scalpels and laser tweezers to study G-quadruplex structures in human telomeres. The goal is to understand how these units are structured and distributed, which could lead to new anti-cancer drugs.
Researchers have developed a method to track the movement of polycyclic aromatic hydrocarbons (PAHs) through the human body, shedding light on their role as carcinogens. The technology uses accelerator mass spectrometry to detect tiny amounts of PAHs in blood and explore how they are processed by humans.
Washington State University researchers are working on a five-year NIH grant project to develop new bone-like coating materials that will allow titanium-based implants to integrate better into the body. The goal is to improve implant success rates, particularly for younger patients and those undergoing revision surgeries.
Researchers reconstructed how fungus-growing ants improved their clonal crops into a robust farming system. The ant farmers lost the ability to produce vital amino acids and enzymes themselves, relying on the fungus for delivery.
Researchers at Scripps Translational Science Institute are using DNA to investigate sudden deaths in San Diego County, aiming to identify genetic mechanisms and develop preventative screening programs. The study hopes to provide closure for families and potentially save lives.
A recent study published in Nature Communications sheds light on chromosome segregation and its impact on cancer development. Researchers discovered that mutations in the BubR1 protein can cause cancer by disrupting correct chromosomal passage.
Researchers at the University of Rochester used imaging technique to show how brain heals itself after surgery, predicting vision recovery based on myelin insulation. This finding could have implications for treating various central nervous system injuries.
Scientists from USGS and Santa Barbara Museum of Natural History discover new genus and species of bivalve mollusk, Wallerconcha, in deep-water sediment cores from the Beaufort Sea. The discovery is named after Dr. Thomas R. Waller and Sara Powell, co-authors of the study.
Researchers identified rare APOA5 gene mutations linked to high triglycerides and increased heart attack risk. The study found that these mutations also raise LDL receptor mutation prevalence, underscoring the role of triglyceride metabolism in early-onset heart attacks.
A recent study by the University of Manchester has investigated the effects of weak magnetic fields on human proteins, including those crucial for health. The research found no detectable impact on key proteins, suggesting that power lines and other electrical devices may be safer than previously thought.
Researchers identified two subtypes of breast cancer, Epi-Basal and Epi-Luminal B, which differ in their epigenetic patterns. The subtype Epi-Luminal B is associated with reduced survival rates and requires adjuvant chemotherapy.
Researchers at Imperial College London discovered an ingredient, inulin-propionate ester (IPE), that stimulates gut hormones to reduce hunger and prevent weight gain. The study found that IPE supplementation reduced body weight and fat accumulation in overweight volunteers.
Added sugars, especially fructose, are likely to have a greater impact on high blood pressure and heart disease than salt. Reducing processed food intake containing added sugars can help mitigate cardiovascular risk. The authors argue that dietary guidelines should be more stringent in limiting sugar consumption, particularly among teens.
A new NYIT study reveals that rats treated with thyroid hormones had a reduced risk of developing dangerous heart arrhythmias following a heart attack. The findings could have important implications for future treatment of human patients with heart failure, who often suffer from atrial fibrillation.
A new study reveals that two-thirds of women treated for early-stage breast cancer in the US receive longer radiation therapy than necessary, despite multiple randomized trials and professional society guidelines showing that hypofractionated radiation is clinically effective and less costly.
A phase-Ib clinical trial found durable responses in almost one out of five patients with metastatic triple-negative breast cancer treated with pembrolizumab. The treatment produced significant activity, with five patients experiencing complete or partial responses, and seven others showing stable disease.
Researchers at Rice University developed a model to quantify the last unknown characteristic of film formation. Hot monomers can make islands grow or knock other molecules off, affecting film properties.
A new study has identified key steps for hospitals to improve care for pregnant mums and babies affected by congenital diaphragmatic hernia (CDH). The report highlights inconsistencies in care delivery, with some areas showing better patient-centered models. Key recommendations include focusing acute care on specialist centers and deve...
A new study predicts eastern Pacific marine species will shift poleward due to climate change, altering fish communities and fishing grounds. The study suggests some species will move into habitats of other marine life to the north, while others may disappear from areas at their southern ends.
A new Rutgers-led research study found that patients with heart disease who receive transfusions during surgeries do just as well with smaller amounts of blood. The study measured overall mortality and found no evidence of increased mortality from cardiovascular disease or severe infection due to the amount of blood given after surgery.
A new study published in the Journal of Studies on Alcohol and Drugs suggests that laws limiting alcohol outlet density can reduce rates of intimate partner violence. Communities with fewer alcohol outlets tend to have lower rates of partner abuse, according to researchers.
Recent research on early hominid diets highlights the limitations of using modern technologies alone to understand their eating habits. A holistic approach is needed, considering factors such as habitat, anatomy, and cognitive abilities. This interdisciplinary method can provide a more accurate picture of our ancestors' diets.
Researchers at Columbia University Irving Medical Center have developed a way to replace the meniscus with a personalized 3D-printed implant infused with human growth factors, promoting tissue regeneration in sheep. The therapy could provide an effective and long-lasting repair of damaged menisci, reducing the risk of arthritis.
Researchers have created the first empty clathrate of a new form of ice, known as Ice XVI, which has significant implications for understanding its physical chemistry. The discovery may lead to improved methods for transporting and storing energy, reducing costs and environmental impact.
Research by University of Zurich linguist Simone Pfenninger found that students with strong German language skills tend to excel in English, even if they start learning the latter at a later age. In contrast, early foreign language learning can sometimes hinder L1 development in the short term.
Researchers found that propolis, a substance from honeybee hives, encourages hair growth in mice by increasing special cells involved in the process. The study suggests that propolis' anti-inflammatory compounds could help treat balding conditions.
A study found that racial and ethnic disparities in acute care narrowed significantly as hospitals improved quality, with nine major disparities mostly disappearing by the end of 2010. Hospitals serving minorities made faster improvements and delivered more equal care to white and minority patients over time.
A study of 9,387 men with fertility issues found a correlation between poor semen quality and various health conditions, including hypertension and skin/endocrine disorders. The study suggests that treating male infertility may also benefit overall health.
Researchers found that a small group of pneumatic devices and wells with frequent liquid unloadings are responsible for the vast majority of methane emissions from natural gas production sites. The study confirms regional differences in methane emission levels, with highest emissions in the Gulf Coast and lowest in the Rocky Mountains.
Researchers at MIT have successfully turned on any desired gene in living cells using the CRISPR/Cas9 system. This breakthrough enables scientists to study gene function and identify genes involved in diseases, such as melanoma. The new method has also been used to screen for genes that confer resistance to cancer drugs.
Researchers identified two compounds that inhibit mitochondrial energy enzyme MDH2, blocking cardiac damage caused by doxorubicin and reducing heart failure risk. The findings suggest that these compounds could improve cancer treatment outcomes while minimizing cardiac toxicity.
A new study by a Pitt researcher reveals that there is limited scientific data on how long the Ebola virus can survive on surfaces, in water, or in liquid droplets. This knowledge gap makes it challenging to develop effective disinfection practices to prevent the spread of the disease.
A study from the University of Texas at Dallas found that family-friendly policies significantly increase productivity and are related to higher labor productivity. The study also discovered a positive relationship between unionization and increased productivity and lower turnover rates.
Researchers at the University of Adelaide found that patients who managed their lifestyle factors were five times more likely to have long-term survival without any further heart arrhythmia. The intensive risk factor management program improved arrhythmia-free survival rates from 18% to 87% after five years.
A new fMRI test can detect neural dysfunction in HIV-positive individuals before they exhibit cognitive decline, according to a Georgetown University Medical Center study. The researchers found that the neural specificity in brain regions associated with face processing is reduced in HIV-positive participants.