The latest issue of Global Heart explores the challenges of delivering critical care in resource-limited settings, where cardiovascular disease is emerging rapidly. Key findings include the need for effective diagnostic resources and treatments for conditions like sepsis, ARDS, and pulmonary vascular disease.
Claudio Silva, a NYU professor, won the IEEE Visualization Technical Achievement Award for his seminal contributions to data visualization and analysis. His work on VisTrails, an open-source data-exploration system, has significantly influenced researchers across various domains.
A McGill University study found that men who had female partners with oral and/or genital HPV infections were more likely to have oral HPV themselves. The prevalence of oral HPV was higher among male smokers, non-monogamous individuals, and those with a partner having oral or genital HPV infection.
A study found that preschoolers with depression had a smaller right anterior insula, which predicts future bouts of depression. Excessive guilt in preschool years is also linked to brain changes and increased risk of recurrent depression.
A team of astronomers detected eight large storms on Uranus's northern hemisphere, including the brightest storm ever seen at 2.2 microns. The storms are thought to be caused by gases such as methane rising in the atmosphere and condensing into highly reflective clouds of methane ice.
A new study reveals that microbicides targeting HIV are less effective when exposed to semen due to its amyloid fibrils, which enhance the virus's infectiousness. Researchers suggest creating a compound targeting both the virus and these protein aggregates to improve drug efficacy.
A new study found that mothers tend to use more emotional words and content when conversing with their daughters than sons. This may lead to girls growing up more attuned to their emotions, having an edge in expressing themselves and coping with emotions.
Researchers have identified a type of adult lung stem cell that contributes to lung regeneration after damage. The study found that these cells, known as p63+/Krt5+, proliferate upon injury and form new alveoli near sites of inflammation, highlighting their potential for therapeutic strategies.
Researchers developed a wireless, light-sensitive film that can stimulate neurons and potentially treat age-related macular degeneration (AMD). The new device outperforms existing technologies in terms of durability, flexibility, and efficiency.
A study found that nearly half of posthospitalization suicides occurred in the top 5% of hospitalizations with highest predicted suicide risk. Targeted expanded posthospitalization care might be effective in reducing soldier suicides.
Researchers found that nitric oxide signals plants to limit nitrogen uptake, allowing for optimal growth without excess pollution. This discovery could inform crop breeding and fertilizer use, resulting in more sustainable agriculture.
Researchers will use brain imaging to discover the brain-behavior connections that influence decisions on goal-setting, activities, and controlling illness. They hope to develop new interventions to motivate patients to take better care of themselves.
Researchers develop computer-based method to predict mechanism of action of natural substances, identifying potential target structures for 210,000 compounds. The software breaks down molecules into smaller fragments, discovering essential parts for the mechanism of action, which can be used to design less complex and easier-to-synthes...
Researchers found that people with one inactive copy of the NPC1L1 gene had lower LDL cholesterol levels and a 50% reduced risk of coronary heart disease. The study suggests that targeting this gene may provide protection against heart attack, but further research is needed to confirm its effectiveness.
Researchers at MIT and Draper Laboratory have developed a new atomic timekeeping approach that could enable more stable and accurate portable atomic clocks. The system suppresses the AC Stark shift effect, allowing for smaller, less expensive devices with improved accuracy compared to current fountain clocks.
Researchers at VCU Massey Cancer Center have discovered a unique approach to treating pancreatic cancer that uses immunotherapy to target cancer cells and stimulate the immune system. The treatment method, known as immunochemotherapy, shows promise in pre-clinical studies with minimal harm to normal pancreatic cells.
A study found that Medicare patients with poor-prognosis cancers who received hospice care had significantly lower rates of hospitalizations, ICU admissions, and invasive procedures at the end of life. Hospice beneficiaries also had lower health care expenditures during the last year of life.
Domperidone has been found to increase milk supply in breastfeeding women with no reported significant adverse effects. Its use is associated with modest improvements in breast milk volume, supporting long-term health benefits for both mothers and babies.
A new study published in PLOS Medicine has developed a 17-gene set to analyze peripheral blood samples and determine which patients are at risk of acute rejection after kidney transplantation. The test, called kSORT, was found to be highly accurate and clinically applicable, with an area under the curve of 0.93.
Research found that most participants underestimated weight and incorrectly identified body shapes, even among healthcare professionals. The study's findings have important implications for weight management support and advice, as many individuals may not be receiving the help they need due to inaccurate assessments.
Scientists from the University of Tokyo have detected silicon and nitrogen-terminated carbon chain molecules in interstellar space using laboratory experiments. The discovery provides valuable information on the formation mechanisms of these molecules and their potential impact on understanding the chemical composition of the universe.
A team of researchers has drawn connections between known regulators of body mass, pointing to possible treatments for obesity and metabolic disorders. They also found intriguing clues that these same molecular pathways may play a role in learning and perhaps even in some forms of brain cancer.
Research shows butterfly eyespots are used to deflect predator attacks, with large and bright eyespots in the wet season making a colorful target for attack. In the dry season, smaller and duller eyespots make the butterfly more difficult to detect and consume.
A new plant species, Dorstenia luamensis, is threatened by cattle ranches and forest destruction following a 50-kilometer mapping error. The reserve's borders were incorrectly placed on maps, putting the unique plant and its biodiversity, including chimpanzees, at risk.
Researchers used supercomputing simulations to analyze ancient DNA from a 24,000-year-old Siberian boy, revealing that modern Europeans are a mixture of three distinct ancestral populations. The study challenges the prevailing view that only two groups mixed in Europe between 7,000 and 8,000 years ago.
MU researchers have catalogued the effects of abnormal enzymes responsible for one type of glycogen storage disease in humans. Their study, published in The Journal of Biological Chemistry, provides promising early-stage results that could aid in patient prognosis and therapeutic development.
Researchers at Brigham and Women's Hospital found that patients without hospice care had significantly higher rates of health care utilization and costs during their last year of life. Hospice care was associated with lower rates of hospitalizations and intensive procedures.
Researchers from Universidad Politécnica de Madrid and the National Institutes of Health provide a wealth of patient imaging data to build tools for diagnosing coronary heart disease. The publication includes a virtual machine with software and data, enabling direct experimentation and annotation.
A new study has identified a human gene that provides natural resistance to typhoid fever. The HLA-DRB1 gene codes for a receptor important in the immune response against invading bacteria. This finding holds promise for developing improved vaccines and treatments for typhoid fever.
Researchers examine how westerly wind pulses impact El Niño's strength, suggesting a link between these events and the phenomenon's duration. Scientists also explore drilling into small volcanoes to better understand future hazards.
A new study found that younger postmenopausal women with normal bone density are at a very low risk of fractures. Without osteoporosis, it took an average of 11 years for just 1% to sustain a vertebral fracture and 3% to sustain a major osteoporotic fracture.
A study of over 26,000 women found that Tdap vaccination during pregnancy was not associated with an increased risk of preterm delivery or small-for-gestational-age birth. However, a higher risk of chorioamnionitis was observed among vaccinated women.
A new oral interferon-free therapy has produced significantly fewer side effects and is prescribed for 24 weeks. Cirrhosis caused by hepatitis C is the leading reason for liver transplantation in the U.S., with patients having lower survival rates than those transplanted for other causes of cirrhosis.
A new transdiagnostic psychotherapy approach, CETA, has been found to be effective in reducing depression and posttraumatic stress symptoms among Burmese trauma survivors living in Thailand. The treatment resulted in a significant reduction of symptoms over an average of 3 months.
A recent study published in the New England Journal of Medicine shows a significant decline in invasive pneumococcal disease cases caused by bacteria resistant to one or more antibiotics. The introduction of pneumococcal conjugate vaccine (PCV) in South Africa has led to substantial reductions in antibiotic-resistant invasive pneumococ...
A new study shows a novel molecular imaging drug is effective in detecting early prostate cancer in soft tissue, lymph nodes, and bone. The drug, Tc-99m MIP-1404, has favorable pharmacokinetics and biodistribution, representing a breakthrough in prostate cancer imaging.
Researchers sent twisted light beams across Vienna, encoding images and demonstrating increased data-carrying capacity. The technology could significantly increase data-rates in classical communication and make secret keys tougher to crack in quantum communication.
A new study found that survivors of heart attacks and strokes experience a rapid decline in physical abilities over time, leading to increased disability and depressive symptoms. The study suggests that these survivors should be screened for functional disability long after discharge from the hospital.
A study in the Journal of Marketing found that chemical farmers resist converting to organic methods because it challenges their belief systems. Organic farmers, on the other hand, report a sense of joy and renewal through their practice.
Researchers at UT Southwestern Medical Center have identified the specific type of cell that gives rise to large, disfiguring plexiform neurofibromas, a finding that could lead to new therapies for preventing tumor growth. The study suggests ways to develop treatments by understanding the steps leading to tumor development.
A new study suggests that companies with strong social responsibility reputations can inadvertently create a 'health halo' around their products, leading to overconsumption and underestimation of calories. This phenomenon can have serious health consequences for individuals and society.
A new study from City University London found that eye movement analysis can detect diseases like glaucoma while watching TV. This method could help clinicians identify the disease earlier, enabling timely treatment before permanent damage occurs.
Research on tool use by primates suggests that ecological opportunity, rather than necessity, is the main driver behind their use of tools. The study found that tool use was not influenced by food scarcity, but rather by calorie-rich and hard-to-reach resources.
Dr Marc Pellegrini has been awarded a $1.225 million fellowship to focus on progressing his research into chronic infections such as HIV, hepatitis B and tuberculosis. The grant will enable him to explore how microbes evade the immune system and apply these discoveries to eradicate these diseases.
Researchers at ETH Zurich have developed a novel gene regulation method that enables thought-specific brainwaves to control the conversion of genes into proteins. The system uses EEG headsets to transmit brainwaves wirelessly to an implant, which regulates gene expression through light-sensitive optogenetic modules.
Researchers at Vienna University of Technology have developed a new laser system to create high-flux X-ray pulses, which will allow for more accurate measurements in various scientific fields. The new technology uses mid-infrared light and can produce up to 25 times higher X-ray flux than previous experiments.
Genomic tests using next generation sequencing technologies face access issues due to inadequate evidence on clinical utility. Experts suggest a four-pronged approach to improve access, including robust validation studies, prioritizing research and evidence, and evolving the evidence review process.
A novel method of altering a protein in milk has been discovered, enabling the delivery of an antiretroviral drug to infants with HIV/AIDS. This breakthrough could greatly improve treatment for the estimated 3.4 million children suffering from the disease.
Researchers at UC San Diego School of Medicine implicated a new gene in non-syndromic autism, suggesting similar molecular pathways among different types of autism. The study used mouse models, induced pluripotent stem cells and the 'Tooth Fairy' project to identify TRPC6 as a novel predisposing gene for ASD.
Yale psychologist Oriana Aragon's study reveals that people cry when they're happy to restore emotional balance. Individuals who express negative reactions to positive news can better moderate intense emotions.
A new study by American Marketing Association found that customers are more likely to buy when they can donate to good causes, with moderate discounts also driving sales. The study suggests that offering charity options alongside products can significantly increase purchases.
Mental health experts in The BMJ warn that UK immigration detention systems are broken and prioritize deterrence over protection, causing harm to detainees' physical and mental health. Experts call for NHS England to ensure detainees are screened for mental health problems and facilities maintain NHS standards.
Researchers have discovered an unexpected tail on asteroid 62412, which was previously known as a typical asteroid. The discovery reveals that there may be up to 100 active asteroids in the main asteroid belt, shedding light on the processes that cause some asteroids to become active.
A new study found that restaurant surcharges and labeling can reduce demand for unhealthy menu items. The study showed that customers are more likely to avoid unhealthy food with a label and a surcharge than without either. This combination is called an 'unhealthy surcharge' and may lead to increased customer trust and loyalty
A University of Utah study found that pathogens killing tree seedlings in drier forests allow more diverse tree species to thrive in the wetter Caribbean environment. This separation is crucial for conservation planning and understanding how tree species adapt to climate change.
A recent survey of symptomatic HIV-positive people in rural Mozambique found that those who initially consulted traditional healers had a 2.4 times longer delay between the onset of symptoms and diagnosis of HIV. The study highlights the need to engage traditional healers in HIV care and provide incentives for referrals.
Researchers found that FKBP51 regulates acute and chronic effects of antidepressants via autophagic pathways in mice and humans. Autophagy markers correlate with antidepressant treatment response in patients with depression.
Researchers create a new material that can store charge and support weight, with potential applications in wearable technology, water filtration, and radiofrequency shielding. The material's flexibility and strength make it suitable for various uses, including improving electrical energy storage.
The TRACE Matrix tool assesses countries' business bribery risks across four domains and nine sub-domains, providing a score from 1 to 100. This allows companies to tailor their compliance practices more effectively.
Nimrod Megiddo recognized for groundbreaking work in algorithmic game theory, linear programming, and combinatorial optimization. His contributions have been highly influential across various areas of operations research and management science.