Articles tagged with Obesity
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Researchers have identified a molecular mechanism behind hyperphagia in obese patients, where specific antibodies stabilize ghrelin, leading to increased appetite. This discovery opens new opportunities for designing treatments targeting this mechanism to reduce excessive food intake.
A recent study published in the British Journal of Nutrition found that obese women voluntarily reduced their dietary intake by 378kcal in response to additional sugar-sweetened drinks. The researchers discovered that these women were able to compensate for most of the extra calories by decreasing energy intakes from other sources.
A recent study published in the Lancet found that young obese women with metabolic disorders are at a higher risk of developing high blood pressure, diabetes, and high cholesterol, which can increase their likelihood of having a stroke. In contrast, young women who are overweight or obese without metabolic disorders do not have an incr...
Research finds obesity may significantly increase the risk of C. difficile infection, particularly in those with no prior healthcare exposure. Additionally, patients with inflammatory bowel disease are also at higher risk, highlighting the need for improved clinical surveillance and monitoring.
Researchers at the University of Cambridge have discovered that genetic mutations in the KSR2 gene can lead to severe obesity and reduced basal metabolic rate. This finding provides evidence for the role of genes in regulating energy use in the body, adding complexity to the body's mechanisms for regulating weight.
WSU researchers found that gestating rats exposed to DDT experienced increased obesity in third-generation offspring, suggesting transgenerational epigenetic inheritance. This effect is believed to be related to how genes are turned on and off in the exposed animals.
A Finnish study found that binge drinking accelerates atherosclerosis and increases the risk of stroke in middle-aged men, particularly those who experience hangovers. The study also highlights the importance of moderate alcohol consumption and managing other risk factors such as hypertension and overweight.
A large prospective study found that patients with a body mass index in the obese range live on average two to three months less after a pancreatic cancer diagnosis compared to healthy-weight patients. Obesity is associated with poorer pancreatic cancer survival rates, even after adjusting for age and disease stage.
A recent study published in the journal Obesity found that home-schooled children were less likely to be obese and had lower calorie intakes than traditionally schooled kids. The study's lead author noted that differences may reflect the unique environment of home-school families, but further research is needed.
A new study reveals that body mass index (BMI) is not an effective predictor of mortality in bariatric surgery patients. Researchers found that sex, smoking status, and diabetes are better indicators of risk. The study suggests that the current practice of prioritizing bariatric surgery for obese women may be misguided, as men who are ...
A novel surgical intervention involves placing an intestinal barrier sleeve in the small intestine to correct obesity and improve glucose metabolism. The method is less invasive and can be removed at any time.
A study of identical twins with significant weight differences found that in half of the pairs, the obese twin had a poorer blood fat profile and increased risk of diabetes. In contrast, the other half showed no difference in metabolic health between the two twins, shedding light on the 'metabolically healthy obesity' phenomenon.
A study published in the Journal of the American Society of Nephrology found that obesity increases the risk of developing chronic kidney disease by suppressing an important cellular process called autophagy. Restoring this process may help protect kidney health in obese individuals.
A CDC study links short and long sleep durations to increased risk of coronary heart disease, stroke, and diabetes. Adults 45+ who sleep six hours or less or more than 10 hours per night are at higher risk for these chronic diseases, the American Academy of Sleep Medicine advises.
A new study by Yale researchers found that the body's energy-producing mitochondria play a crucial role in regulating appetite and obesity risk. Dynamic changes in mitochondria can either spur or stop obesity, highlighting the importance of mitochondrial plasticity in maintaining healthy energy levels.
Melatonin consumption helps regulate body weight control by stimulating the appearance of 'beige fat', a type of fat cell that burns calories. Chronic melatonin administration also heightens thermogenic effect of exercise and exposure to cold.
A new study by NYU Steinhardt researcher Niyati Parekh suggests that disturbances in body insulin and glucose levels are associated with an increased risk of obesity-related cancers. The research, which analyzed data from the Framingham Heart Study, recommends lifestyle changes to alleviate these disturbances as a cancer control tool.
A study found that combining intensive diet and exercise leads to greater improvements in knee pain and function compared to diet alone or exercise alone. Participants who lost weight through diet and exercise had less knee pain, better function, and faster walking speed.
Researchers found that tempol, an anti-oxidant drug, reduces weight gain in mice fed a high-fat diet. The drug targets the gut microbiome, specifically reducing Lactobacillus levels and increasing tauro-beta-muricholic acid, which inhibits FXR and regulates metabolism.
The Sangre por Salud Biobank is a collaboration among Mayo Clinic, Mountain Park Health Center, and Arizona State University to support studies in obesity, metabolism and diabetes in the Latino population. The biobank aims to enroll 2,000 participants over four years, with a special emphasis on cardiometabolic risk and obesity.
A nationwide study found that older adults who maintained a stable weight were more likely to survive than those who gained weight. The results suggest that small amounts of extra weight may be protective against mortality in older age, possibly due to reduced nutritional deficiencies and chronic disease.
Researchers found that 30 minutes of daily exercise is just as beneficial as an hour-long workout in improving energy levels and motivation for a healthy lifestyle. The study suggests that moderate exercise can significantly impact daily practices and overcome cultural barriers to change.
Scientists at UTHealth Medical School developed a brown fat detection method that worked in an animal model, providing a new tool to fight obesity. The peptide probe can be used for whole-body imaging and localization of brown fat tissue.
A new study published in Obesity found that physical activity and weight loss conducted together results in improved body composition and reduced cardiovascular disease risk. The study showed that intentional weight loss can have positive health benefits for older adults, particularly when accompanied by physical activity.
A recent study found that adding avocado to meals may help reduce hunger and improve insulin response in healthy overweight adults. The research suggests potential weight management benefits, offering promising clues for future studies.
The UK's sleep disorder services are severely lacking, with high rates of obstructive sleep apnea (OSA) in certain regions going undiagnosed and untreated. Despite the rising demand due to an aging population, many areas have limited access to specialized care, leading to a concerning mismatch between need and supply.
Research suggests that obese individuals' stomachs become desensitized to fullness signals, making it difficult to maintain weight loss. This could explain why many people regain weight after dieting. The study's findings have strong implications for those struggling with obesity and weight management.
A novel biomarker, 2-aminoadipic acid (2-AAA), has been identified that can predict diabetes risk up to 12 years in advance. Individuals with high levels of 2-AAA concentrations had a fourfold risk of developing diabetes compared to those with lower levels.
Researchers developed a novel DiaRem score to predict likelihood of diabetes remission after gastric bypass surgery. The score considers four factors: insulin use, age, haemoglobin A1c concentration, and type of anti-diabetic drugs.
Researchers are investigating the links between maternal nutrition, BPA exposure, and offspring obesity. Studies aim to understand how neural development in the womb can lead to overeating and obesity later in life.
A study presents findings that obesity and cigarette smoke exposure can have a triple health threat, impacting key mechanisms of metabolism in the lung and liver. The combination may alter the body's ability to metabolize prescription drugs, increasing the risk of developing lung cancer.
A recent study found that people who are obese are more likely to experience occasional migraines, with obese individuals being 81% more likely to have episodic migraine. The research suggests that promoting healthy lifestyle choices for diet and exercise may be beneficial in managing episodic migraine.
Researchers found that adding a mental health component to school-based lifestyle programs for teens can lead to improved grades, lower obesity rates, and reduced substance use. The program, called COPE, emphasizes cognitive behavioral skills building and was found to sustain positive outcomes for six months.
A new University of Michigan study reveals that incoming Medicaid enrollees may be younger, whiter, and healthier than current beneficiaries. These individuals are more likely to be smokers and heavy drinkers. Overall, the expansion could bring in a new, healthier group with different demographic characteristics.
Obese teenagers who lose weight are at risk of developing eating disorders such as anorexia nervosa and bulimia nervosa. Early intervention is crucial for a good prognosis, but these adolescents often go undiagnosed due to positive provider perceptions of weight loss.
A study by University College London found that education is a key factor in reducing the negative impact of urban living on women's health. Women with no formal education working in sedentary occupations were twice as likely to be 'centrally obese' compared to those with some degree of formal education.
A new study found that sleep deprivation leads to increased food purchasing the following day, with participants buying more calories and grams of food. Additionally, ghrelin levels were higher after total sleep deprivation, but this increase did not correlate with food purchasing behavior.
A study found that human gut bacteria can transmit lean or obese traits to mice depending on their diet, highlighting the importance of diet in shaping gut microbiota. The researchers identified specific bacterial species that play a role in metabolism and obesity, paving the way for personalized probiotic therapies.
A new study found that genetic testing for weight gain risk does not deter people from weight loss efforts, but rather alleviates emotional stress and stigma associated with weight control. The results suggest that individuals recognize the importance of both genetics and behavior in maintaining a healthy weight.
A variant of FGF21, LY2405319, has been shown to improve metabolism in obese humans with type 2 diabetes by reducing LDL cholesterol and triglycerides while increasing HDL cholesterol levels. The hormone also reduced body weight and fasting insulin, and increased adiponectin.
A study by Helmholtz Munich found that increased body weight deteriorates physical health, but improves mental well-being in women. The researchers analyzed data from over 3000 people, revealing the complex relationship between body weight and overall health.
Research presented at the ESC Congress found that low body mass index (BMI) is associated with worse cardiovascular outcomes in patients with hypertension and glucose intolerance. Patients with lower BMI had a higher risk of cardiovascular events compared to those with middle or higher BMI, according to the study.
Research presented at ESC Congress found that underweight women with coronary artery disease (CAD) have a 2-fold increased risk of death. Maintaining weight or gaining weight may help reduce this risk in obese women, while losing weight increases the risk in underweight women.
A study of 98,658 Chinese adults found nearly 12% had diabetes and 50% were at risk for prediabetes. The prevalence varied by age, sex, urban vs. rural residence, and economic development.
Research published by the European Society of Cardiology found that metabolically healthy women with a normal weight and those who are overweight but metabolically healthy have similar cardiovascular disease risks. The study followed over 260,000 women for an average of 5 years after childbirth.
A University of Utah study found that higher-intensity activity, even in short bouts, can lower the risk of obesity and promote weight loss. The research used data from over 4,500 adults and showed that daily minutes spent in high-intensity activity can offset up to half a pound of weight.
High waist circumference and severe obesity are associated with increased mortality in heart attack survivors. Losing abdominal fat through lifestyle interventions is crucial for reducing long-term cardiovascular complications.
Research shows that behavioral interventions improving delay of gratification can work equally well with overweight and obese women as with lean women. When participants mentally simulated future events, they reduced delay discounting and displayed fewer differences between groups.
Researchers at Boston University School of Medicine advocate for a more individualized approach to diagnosing obesity, considering factors beyond Body Mass Index (BMI). This shift could help identify healthier obese individuals and prevent unnecessary medical interventions.
Researchers identified two groups of individuals distinguished by the richness of their gut microbiota, with those having a poor gut microbiome being more likely to experience obesity and related metabolic issues. The study also found that certain bacterial species may play a protective role against weight gain.
A recent study published in Nature found that approximately 1 in 4 individuals have fewer than average intestinal bacteria, leading to reduced diversity and increased inflammation. This lack of gut bacteria is associated with a higher risk of obesity, type 2 diabetes, and cardiovascular diseases.
Research reveals that individuals with lower bacterial species in their intestines are more susceptible to developing complications related to obesity, including cardiovascular diseases and diabetes. A diverse flora appears to play a crucial role in maintaining overall health.
A recent study found that reduced levels of inflammation may explain how some obese individuals remain metabolically healthy. Inflammation is associated with a higher risk of diabetes and heart disease, but some obese people do not develop high blood pressure or unfavorable cholesterol profiles.
A new study from Duke University finds that a 'maintain, don't gain' approach can be effective in preventing obesity-related health issues among premenopausal black women. By focusing on maintaining current weight, these women can reduce their likelihood of experiencing chronic diseases later in life.
A behavioral weight gain prevention intervention was effective in preventing weight gain among socioeconomically disadvantaged black women. The Shape Program, which included weekly self-monitoring and monthly counseling calls, resulted in a significant reduction in weight at 12 months compared to usual care.
The study found a significant increase in women's risk of developing kidney stones, with more cases being seen in emergency departments over a four-year period. The rate of hospitalization remained stable, but the use of CT scans to diagnose kidney stones may contribute to the rise in emergency department charges.
A study by Boston University researchers found that vigorous physical activity was associated with a lower risk of obesity among young African-American women. The study, which followed 20,259 women for 14 years, revealed that increasing levels of vigorous exercise resulted in a 23% lower incidence of obesity.
Research suggests that weight loss surgery in female rats prior to conception has no positive impact on the metabolic health of their offspring. In fact, the study found that the metabolic health of VSG-treated offspring was worse than that of obese controls, with lower birth weights and increased susceptibility to glucose intolerance.
A recent study found that glucagon, a hormone involved in regulating appetite, fails to induce feelings of fullness in obese individuals. However, it successfully suppresses hunger pangs in people with type 1 diabetes, according to researchers from The Endocrine Society.
A new Duke University study found that restaurant websites with easy-to-access calorie information can influence customer ordering decisions. Despite this, in-store marketing and psychological factors often override healthy options.