Articles tagged with Obesity
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Research suggests that adding words related to health and weight on posters, menus, or recipe cards can stimulate healthy food choices among dieters and overweight individuals. This technique has great potential as an intervention to help weight control, as it is unobtrusive, easy to implement, and low in cost.
A new study found that gastric bypass surgery changes the gut microbiota composition in rats, increasing beneficial bacteria and altering peptide release. This shift resembles prebiotic treatment effects, suggesting a potential link between postsurgical gut modulations and improved metabolic outcomes.
A new UC Davis study found that being overweight or obese alone is not linked to an increased risk of death in the short-term. However, severely obese individuals with diabetes or hypertension do face a higher risk of mortality, emphasizing the importance of weight loss and managing co-occurring health conditions.
Researchers describe the biological mechanisms behind protein's appetite-suppressing effects, identifying specific receptors involved in intestinal gluconeogenesis. This understanding paves the way for new avenues in obesity treatment by controlling fullness sensation over long periods.
A recent Vanderbilt University Medical Center study has found that obesity is associated with a higher risk of acute kidney injury (AKI) following cardiac surgery. The study, which followed 455 cardiac surgery patients, found that a higher body mass index (BMI) was linked to a greater risk of AKI, with patients weighing more than avera...
A new study by UNC Chapel Hill researchers reveals Chinese teenagers have a significantly higher rate of diabetes (1.9%) compared to their US counterparts (0.5%). The study also found high levels of inflammation and cardiometabolic risk factors in Chinese children, with over one-third having at least one risk factor.
Researchers mapped gut-brain signaling after protein-rich meals to limit food intake. Peptides from digested proteins block opioid receptors, suppressing hunger and glucose release in the intestine.
Researchers from A*STAR have identified a novel signalling pathway controlling both obesity and atherosclerosis in mice. The study found that Wip1-deficient mice were resistant to weight gain and atherosclerosis through increased autophagy, highlighting a potential new approach for treating these conditions. Further investigation into ...
A new UCLA study found that obesity and a higher waist circumference reduce risk of adverse outcomes in advanced heart failure patients. Men and women with high BMI and waist circumference had significantly better event-free survival rates than those with normal weight.
Food expert Kelly Brownell argues that government regulation is necessary to counterbalance the food industry's influence. The industry prioritizes profits over public health, distorting science and compromising scientists to achieve its goals. Voluntary changes are insufficient to address the obesity crisis.
A Wayne State University researcher is conducting a study to understand the link between obesity and severe flu outcomes. The study aims to identify specific factors that contribute to poor health outcomes in obese patients with influenza, with the goal of developing targeted treatment strategies.
A study of 92 menopausal women found that regular physical activity can lead to a decrease in hot flash symptoms. The researchers used objective and subjective methods to track the frequency of hot flashes, finding that exercising actually reduced symptoms in most participants, contradicting previous assumptions.
Obese appendectomy patients who undergo minimally invasive laparoscopic procedures experience fewer complications, longer hospital stays, and higher rates of infectious complications compared to open appendectomy. This study suggests that minimally invasive operations may be less risky for obese patients, reducing morbidity by up to 57%.
A stepped-care approach to weight loss resulted in clinically meaningful weight loss with lower costs compared to a standard behavioral weight loss intervention. The study found that the stepped-care intervention was more cost-effective, with a mean cost per participant of $358 compared to $494 for traditional programs.
A new study suggests that viewing images of high-calorie foods stimulates the brain's appetite control center, leading to increased desire for food. The research found that this stimulation may contribute to overeating and obesity, particularly in high-risk populations such as Hispanic young women.
The US Preventive Services Task Force recommends that clinicians screen all adult patients for obesity and offer intensive behavioral interventions. While medium- to high-intensity counseling produced small short-term improvements in cardiovascular health, the task force concludes that these interventions are more effective when delive...
USC researchers found that viewing pictures of high-fat foods stimulates appetite and reward centers in the brain, increasing hunger and desire for certain foods. Consuming sugary drinks also increases desire for savory foods, particularly fructose.
A new animal study finds that oxytocin helps regulate food intake and energy metabolism without causing adverse effects. Oxytocin administered through daily injections or implanted mini pumps reduced food consumption, body weight, and liver fat, improving glucose tolerance and reducing abdominal fat.
Research found that SFRP5-deficient mice showed increased metabolic activity and were resistant to diet-induced obesity, revealing the mechanism of SFRP5-mediated fat cell generation. The study suggests targeting the WNT signaling pathway could be a therapeutic approach to treat obesity.
Scientists identify WNT signaling pathway as potential therapeutic target for obesity. Antibiotic treatment after Lyme disease shows fluorescent bacterial debris remains without causing infection. Oxidative stress contributes to parasite persistence in host tissues, opening new avenue for anti-Trypanosoma cruzi drugs.
A new study found that weight loss reduced the prevalence of low testosterone levels in overweight, middle-aged men with prediabetes by almost 50 percent. The study involved nearly 900 men and showed that lifestyle modification, rather than medication, can increase testosterone production.
Researchers discovered a key brain receptor that regulates gastric emptying and food intake. Mice lacking this receptor showed accelerated obesity and faster food consumption.
Researchers at the University of Michigan have made a surprising finding about WNT signaling and its role in fat cell growth. They discovered that Sfrp5, a molecule previously thought to have an opposing effect, actually stimulates fat cells to grow larger and burn fat slower.
A new study suggests that ghrelin increases the incentive for humans to eat high-calorie foods, even when already full. Rats without the ghrelin receptor gene ate less sweet treat after a meal compared to those with the intact gene.
Adults exposed to secondhand smoke have higher rates of Type 2 diabetes and obesity compared to nonsmokers. They also experienced insulin resistance, higher fasting blood glucose, and a higher body mass index.
A new study finds that physical fitness significantly lowers the risk of death in diabetes patients with heart abnormality. Diabetic patients who were physically fit had a lower risk of death compared to those who were not physically fit, regardless of the presence or absence of left ventricle wall thickness.
A new study reveals that gastric bypass surgery successfully cures Type 2 diabetes in 92% of obese patients, but the disease recovers in approximately 21% of them within three to five years after surgery.
Researchers identify marker of successful dieters, finding that a pre-diet leptin/ghrelin ratio can predict which individuals will maintain weight loss and who will not. The study shows that this ratio can be used to individualize weight-loss therapeutic programs, leading to improved obesity management.
Researchers used deep brain stimulation to treat binge eating in mice and found a significant reduction in consumption of high-fat food. The study suggests that deep brain stimulation may be an effective therapy for obesity by modulating activity of neurons expressing the type 2 dopamine receptor.
A new study by The Endocrine Society found that a combination of diet-induced weight loss and frequent exercise almost doubled the improvement in insulin sensitivity compared to dieting alone. This suggests a distinct complementary effect of exercise on diet-induced weight loss, according to the study.
A new study published by Ohio State University found that omega-3 fatty acid supplements can lower inflammation in healthy but overweight middle-aged and older adults. After four months of supplementation, participants experienced a significant decrease in inflammatory markers, with the low-dose group showing a 10% reduction in interle...
A new study by University of Iowa researchers shows that a natural substance found in apple peel can partially protect mice from obesity and some of its harmful effects. Ursolic acid increases muscle and brown fat in mice on a high-fat diet, leading to increased calorie burning and reduced obesity, pre-diabetes, and fatty liver disease.
A high-fat/calorie diet has been shown to accelerate the development of pancreatic cancer in both human epidemiological studies and mouse models. In the latter, mice fed a diet rich in fat and calories developed obesity, insulin resistance, and inflammation, all conditions that can stimulate the growth of precancerous cells.
A new series by PLOS Medicine examines the role of the multinational food industry in shaping global health policies. Guest editors Marion Nestle and David Stuckler argue that public health professionals must recognize Big Food's influence and take action to expose and regulate its interests.
A study found that adults who underwent weight-loss surgery had a significantly higher risk of developing alcohol use disorders two years after surgery. The study, which followed 1,945 participants, found that the risk was highest among those who had undergone Roux-en-Y gastric bypass surgery.
A study found that bariatric surgery, especially Roux-en-Y gastric bypass, increases the risk of alcohol use disorders (AUD) in patients. The prevalence of AUD symptoms was higher in the second postoperative year compared to before and after surgery.
A study estimated the total mass of the human population, defining its distribution by region and proportion due to overweight and obesity. The world's biomass would increase by 58 million tonnes if all countries had the same average BMI as the USA, equivalent to an additional 935 million people.
A new model predicts the effectiveness of weight-loss groups based on their psychological meaningfulness to members. The study aims to generate a comprehensive understanding of group participation's impact on health and contribute to future development of weight-management programs.
A new study has identified a genetic factor associated with lean type 2 diabetes patients, indicating that genetic predisposition may vary depending on body type. The 'Jack Spratt' gene is linked to an increased risk of the disease in lean individuals, contrasting with obese patients where other factors are more influential.
A study by a CCNY-led team found correlations between the spread of obesity and food marketing and distribution patterns. The researchers suggest that collective behavior plays a significant role in the spread of the epidemic, not individual factors such as genetics or lifestyle choices.
Three studies link obesity and depression to excessive daytime sleepiness, with weight loss shown to improve symptoms in those who lost weight. The research highlights the importance of addressing these conditions to prevent related health risks and accidents.
A new study found that African American women from low-income backgrounds experience greater weight gain and increased obesity risk due to socioeconomic factors. Women with higher education levels are less likely to become obese, suggesting education as a protective factor against weight gain.
A recent study using brain scans found that sleep-restricted individuals exhibit a distinct neural response to unhealthy foods, activating reward centers more intensely than those with adequate sleep. This response is associated with increased consumption of fattening foods after sleep restriction.
A recent study published at EULAR 2012 found that obese patients with psoriatic arthritis have a lower chance of achieving minimal disease activity when treated with anti-TNFs. However, following a hypocaloric diet can increase the likelihood of achieving treatment goals.
A natural milk ingredient called nicotinamide riboside has been found to protect against obesity in mice. It works by boosting levels of NAD+, a molecular sidekick for SIRT1, which helps with metabolism and longevity.
A new study from the University of Exeter has identified a genetic predisposition to Type 2 diabetes in lean patients, contradicting the long-held assumption that obesity is the primary cause. The study found that genetic variants near the LAMA1 gene are linked to type 2 diabetes risk only in lean patients.
A recent study found that a specific gene linked to fat tissue inflammation may protect against diet-induced obesity-related health problems. The researchers discovered that overexpressing this gene increased fat deposition while suppressing inflammatory responses and improving insulin sensitivity in genetically modified mice.
Researchers found that high levels of interleukin-6 (IL-6) prolong inflammation in obese mice with acute pancreatitis. IL-6 is also linked to the severity of the disease in obese subjects.
A study found that female fat prejudice persists even after weight loss, with participants viewing thin women with a weight loss history as less attractive. The researchers also discovered that negative attitudes towards obese people increase when participants are falsely told that body weight is easily controllable.
New research published in Hepatology found that moderate exercise does not improve lipoprotein concentrations in obese patients with non-alcoholic fatty liver disease. While exercise reduced intrahepatic triglyceride content, it did not change liver lipoprotein levels or body weight.
Obese patients have an increased risk of developing kidney damage, or acute kidney injury, after heart surgery. Oxidative stress associated with obesity plays a role in this increased risk. Acute kidney injury affects 5% to 30% of heart surgery patients.
A new study finds that sleep disordered breathing and nocturnal hypoxemia independently predict both glycosylated hemoglobin levels and type 2 diabetes mellitus. Moderate and severe obstructive sleep apnea syndrome were significant predictors of prevalent T2DM and HbA1c levels, even after adjustment for obesity.
A study published in the American Journal of Clinical Nutrition found that variations in certain 'obesity genes' are associated with increased snacking, high-fat foods, and more calories per day. These findings suggest that modifying eating habits may help minimize genetic risk for obesity.
Researchers from Sichuan Agricultural University and BGI reported the atlas of DNA methylomes in porcine adipose and muscle tissues, providing a valuable epigenomic source for obesity prediction and prevention. The study found that different methylated regions in promoters play a more important role in regulating gene expression and ar...
Research at the University of Montreal Hospital Research Centre reveals that high-fat diets can cause chemical reactions in the brain similar to illicit drugs, leading to depression. Mice studies show signs of anxiety and depression after a higher-fat diet, with altered brain chemistry and hormone levels.
A review of medical records suggests that obese patients present with more advanced stage and aggressive forms of papillary thyroid cancer. The study found that higher BMI was associated with more advanced disease stage at presentation, particularly in the obese and morbidly obese categories.
New research reveals that obese adolescents, even those without symptoms of heart disease, already have structural and functional changes to their hearts. The study found that measures of heart size and function were increased in parallel to BMI, indicating damaged hearts with thicker walls and impaired systolic and diastolic function.
Scientists at Salk Institute found that mice who ate for 8 hours a day were healthier than those who ate freely, regardless of diet quality. Regular eating times and extended fasting may help prevent obesity, diabetes, and liver disease.
Researchers found that mice on a high-fat diet who ate in restricted eight-hour windows gained less weight, suffered less liver damage, and had lower levels of inflammation compared to those with unrestricted access. The study suggests that our body clocks may be out of sync with our eating habits, leading to metabolic issues.
Researchers at Weill Cornell Medical College have identified a novel base modification in RNA, which pervades the transcriptome and affects up to 20% of human mRNA. The discovery reveals widespread effects on gene expression, with links to diseases such as cancer, autism, and schizophrenia.