Articles tagged with Obesity
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A study by the University of Colorado Anschutz Medical Campus suggests that a healthy lifestyle during menopause, including diet and exercise, can lower breast cancer risk. In obese postmenopausal women, excess calories fuel tumor growth, but in lean counterparts, they are stored in healthy tissues.
A study by University of Illinois researchers found that reducing daily automobile travel and caloric intake both correlate with body weight reduction. The study predicts a 0.21 kg/m2 decrease in national average BMI after six years if all adults drove 1 mile less per day.
A recent study published in Nature Medicine identified a key protein called mitoNEET that plays a crucial role in fat cell metabolism. Elevated levels of this protein were found to expand fat tissue without leading to obesity-related health issues, such as type 2 diabetes.
A study by Wake Forest Baptist Medical Center reveals that hair care complications are a primary factor deterring African-American women from exercising. The research found that over 40% of respondents reported avoiding exercise due to hair-related issues, with many using heat straighteners or chemical products to style their hair.
Researchers found that aerobic exercise led to greater weight and fat loss compared to resistance training, which only increased lean body mass. The combination of both exercises showed mixed results but provided a significant decrease in waist circumference.
Researchers found an inverse association between low adiponectin plasma levels and the risk of pancreatic cancer. The study suggests that metabolism plays a role in the pathophysiology of pancreatic cancer, potentially leading to improved survival rates with early detection and therapeutic interventions.
A new study by the University of Montreal found that ending a high-fat diet can cause withdrawal-like symptoms and increased sensitivity to stress in mice. The research suggests that brain chemicals associated with depression are altered by diet, leading to a vicious cycle of poor eating.
Two diabetes lifestyle interventions led to significant weight loss and improvements in waist circumference and fasting plasma glucose levels for overweight or obese adults. The adapted Diabetes Prevention Program (DPP) lifestyle interventions resulted in a 2.2-2.9 BMI reduction over usual care at month 15.
A study published in Biological Psychiatry found that a medication called naltrexone can help women who quit smoking keep their weight off. The drug reduced weight gain in women by more than half, compared to those who took a placebo, and improved their overall success rate.
Researchers performed brown fat transplants in mice to treat obesity, finding significant reductions in body weight and improvements in glucose metabolism. The transplanted brown fat secreted hormones that mediated metabolic effects throughout the body.
A preclinical study published in Cancer Research found that obesity and overfeeding during menopause together drive aggressive tumor growth and progression. Obesity-related metabolic changes allowed breast tumors to accumulate glucose and promote proliferation.
New research at the University of Missouri suggests that eating fewer, larger meals can be more beneficial for obese women than consuming small meals throughout the day. The study found that this approach lowered blood-fat levels and reduced the risk of developing heart disease.
Researchers at VCU Massey Cancer Center have identified a potential mechanism for reducing obesity by targeting the production of enzyme Tyk2. The study found that Tyk2 helps regulate brown adipose tissue (BAT), which is responsible for energy expenditure and maintenance of body temperature. By manipulating Tyk2 levels, scientists were...
A recent study published in BMJ Open found that low-income individuals have poorer adherence to the Mediterranean diet, leading to higher rates of obesity. The researchers analyzed data from 13,000 participants and discovered a significant association between income levels and dietary habits.
Research suggests that people with high BMI may benefit from different antihypertensive treatment regimens than those with normal weight. The study found that a combination of benazepril and amlodipine was equally effective across all weight categories, while diuretic-based regimens were more effective in obese individuals.
A new mouse study challenges the widely held view that obesity is caused by high insulin levels. Instead, it suggests that chronically low insulin levels can help prevent weight gain on a high-fat diet. The research provides direct evidence in mammals that circulating insulin drives obesity.
A new study suggests that daily exposure to low-magnitude mechanical signals partially rescues B- and T-cell populations damaged by obesity, improving immune function. Brief daily vibration interventions showed promise in obese mice, potentially leading to a cheap and drug-free way for people to regain health.
Researchers found that men with higher visceral and total abdominal fat had lower failure load and stiffness, two measures of bone strength. Muscle mass was also positively associated with bone strength. The study suggests that excess belly fat is a risk factor for bone loss in obese men.
Researchers found that gastric bypass and adjustable gastric banding produce similar therapeutic benefits in obese patients. Both procedures equally improved insulin sensitivity and glucose tolerance after weight loss, with weight loss itself being the primary driver of these effects.
Researchers at McMaster University discovered a novel molecular basis for depression, finding the FTO gene is associated with an eight per cent reduction in the risk of depression. The study found no link between obesity and depression, contradicting common perception that obese individuals are more likely to be depressed.
Patients who attended five follow-up office visits lost an average of 113 pounds, compared to 57 pounds for those with only two follow-ups. The study highlights the importance of patient follow-up in achieving optimal weight loss after gastric bypass surgery.
Researchers created a culturally relevant guidebook to improve Hispanic health and behaviors, focusing on physical activity and nutrition. The guidebook was well-received by community residents and addressed the Latino Paradox, highlighting the shift in healthy eating habits when immigrants arrive in the US.
A recent study from Michigan Medicine found that 16% of emergency room patients aged 14-20 may have undiagnosed binge eating, bulimia, or other eating problems. Those with signs of eating disorders were also more likely to show signs of depression and substance abuse.
A new study reveals that individuals with Prader-Willi Syndrome may have an impaired autonomic nervous system, leading to abnormal heart rate variability after meals. The findings suggest potential alternative treatments for the condition, which is characterized by insatiable appetite and high cardiovascular risk.
Researchers at the University of Adelaide have identified a genetic link between pre-eclampsia and a variant of the AGT2R gene. Women who are overweight or obese during pregnancy are more likely to carry this variant, which increases their risk of developing the condition.
Researchers have engineered natural gut peptides to carry small steroids, improving insulin secretion, blood glucose, and body weight in mice. The study's findings suggest a potential breakthrough in treating type 2 diabetes and metabolic syndrome, with minimal risk of estrogen-related side effects.
Researchers at Indiana University found a way to combine two hormones into a single molecule, producing more effective weight loss with fewer side effects. The hormone combination targets the hypothalamus and pancreas, reducing the risk of cancer and stroke.
Researchers found that limiting carbohydrates to dinner reduced hunger scores, improved anthropometric outcomes, and lowered inflammatory markers in obese individuals. The innovative dietary pattern led to changes in hormonal secretion patterns favoring satiety and reducing metabolic risks.
A new study by University of Pennsylvania researchers found that deleting the Arntl clock gene in fat cells causes mice to become obese due to a shift in eating timing. Supplementing with fish oil-like fatty acids can rescue this phenotype.
A new study by Hospital for Special Surgery reveals that morbidly obese patients have similar pain and function outcomes to non-obese patients after total knee replacement surgery. The research challenges the long-held assumption that obesity is a contraindication to joint replacement, with patients achieving great outcomes.
Researchers found that children need at least seven minutes a day of intense physical activity to prevent weight gain and obesity. The study tracked over 600 kids aged 9-17 and showed that vigorous activity reduced the risk of unhealthy weight, while sedentary behavior was common.
Veterinary scientists found that obese dogs can experience metabolic syndrome, characterized by increased blood insulin and low adiponectin levels. The study showed that successful weight loss improved metabolic abnormalities in obese dogs.
A systematic review of over 200,000 participants found that maternal overweight and smoking during pregnancy significantly increase the risk of childhood overweight. High birth weight and early rapid weight gain also contribute to this risk. Breastfeeding can help mitigate this risk to some extent.
Research at Beth Israel Deaconess Medical Center has uncovered new insights into energy balance, a complex interchange between the brain's hypothalamus and energy expenditure. The study reveals that GABA neurotransmitter selectively drives energy expenditure and helps explain the fat-burning properties of brown fat.
Researchers developed a mouse model of obesity where the proopiomelanocortin gene can be turned on and off to study the impact of chronic weight gain. Turning the gene back on after prolonged obesity reduced its effectiveness.
Old Order Amish children are twice as physically active and three times less likely to be overweight than non-Amish peers. This high level of activity is inversely correlated with their body mass index, suggesting a protective effect against developing Type 2 diabetes.
Teenagers with severe obesity can benefit from gastric bypass surgery, significantly improving their health and quality of life. The study found that teenagers lost an average of 96.8 pounds following surgery, reducing risk factors for cardiovascular disease.
Research suggests obese patients may have an advantage over nonobese patients in certain health situations, such as septic shock and acute asthma exacerbation. Obese individuals experience lower mortality rates and fewer near-fatal exacerbations compared to nonobese patients.
A recent study found that 39% of high school students experienced excessive daytime sleepiness, despite most sleeping fewer than 7 hours per night. The researchers suggest a potential sleep disorder may be present in these students.
Thomas Jefferson University researcher Scott Waldman receives a $1.2 million NCI grant to investigate the relationship between obesity and cancer, with a focus on guanylyl cyclase C hormone receptor. The research aims to understand how obesity increases colorectal cancer risk and potentially identify a therapeutic target.
A new study found that sleep architecture, not just duration, affects hunger and food intake in healthy adults. Researchers discovered that shorter stages of deep sleep and less REM sleep are associated with higher hunger levels and increased calorie consumption from fat and carbohydrates.
Researchers found that ovulation rates and quality remained unchanged after bariatric surgery, with only a minor shortening of the menstrual cycle. Weight loss improved sexual function, particularly desire and arousal, in obese women seeking pregnancy.
Studies reveal that diet influences brain mechanisms linked to obesity, diabetes, binge eating, and high-calorie meal cravings. Researchers aim to develop new treatments and raise awareness about the mental health implications of dietary choices.
A recent NIH study analyzed data from participants on reality TV show 'The Biggest Loser' to find that exercise plays a key role in reducing body fat while preserving muscle mass. Adopting moderate lifestyle changes, such as 20 minutes of daily vigorous exercise and a 20% calorie restriction, can help sustain weight loss and avoid weig...
New research from UTHealth suggests that fat progenitor cells in obese individuals can fuel tumor growth by supporting blood vessel formation. This discovery has the potential to help prevent or slow down cancer progression.
Scientists at the University of Michigan have made a groundbreaking discovery in understanding how the hormone leptin regulates metabolism and body weight. By visualizing the interaction between leptin and its receptor, researchers may develop new drugs to overcome leptin resistance, a key factor in obesity.
A new NIH-funded study found that group-based weight loss treatment, led by health professionals or peer counselors, is effective in helping overweight and obese adults lose significant weight. The study, conducted at Baruch College, shows that Weight Watchers participants lost more weight than those in the combined treatment approach.
McGill researchers identified a small region in the genome linked to psychiatric disease and obesity, specifically through BDNF deletion. The study found that individuals with BDNF deletions exhibited major depression, anxiety, and obesity, with weight gain associated with age.
New research reveals bariatric surgery does not significantly improve obstructive sleep apnoea in severely obese individuals. Weight loss through surgical or medically-supervised means results in comparable improvements in OSA severity.
The research highlights the need for effective public health leaders to address significant health challenges, citing examples of successful individuals like Jamie Oliver. It suggests that current public health professionals may not be equipped to lead and influence policy, leading to calls for greater leadership training and support.
The proportion of severely obese Americans has increased by 70% since 2000, with over 15 million adults classified as morbidly obese. The trend is slower than previously reported, suggesting a potential slowdown in the growth of severe obesity.
Research indicates diets high in saturated fat and refined sugar may impair brain function in obese individuals, leading to increased overconsumption of high-calorie foods. Obesity-related changes may also lead to permanent cognitive decline, making it a lifelong battle to maintain weight loss.
Overweight adolescents who engaged in regular exercise showed improvements in scholastic competence, social competence, and body image, according to a recent study. The researchers found that even modest doses of aerobic exercise had a positive impact on mental health, including psychological empowerment and reduced emotional distress.
A recent study examines the trends of knee replacement procedures among Medicare patients over a 20-year period, revealing increased volume, per capita utilization, and outcomes. The analysis found a rise in primary and revision TKA procedures, as well as hospital readmission rates and infectious complications.
Research finds that obesity promotes prostate cancer growth by changing gene expression in fat surrounding the prostate, increasing risk of aggressive disease. The study suggests a personalized approach to lifestyle and therapeutic strategies for overweight men with prostate cancer.
Researchers found that greater sugar-sweetened beverage consumption is associated with a higher genetic susceptibility to high BMI and increased obesity risk. The study suggests that environmental factors can amplify the genetic risk of obesity by consuming sugary drinks.
Researchers identified miR-34a's role in fatty liver disease and Type II diabetes. Blocking miR-34a improved metabolic outcomes, including decreased liver fat and improved blood glucose levels.
The study found that obstructive sleep apnea is associated with higher rates of preeclampsia, cesarean deliveries, and NICU admissions. Women with sleep apnea were more likely to deliver babies with respiratory distress, highlighting the need for better screening and treatment during pregnancy.
A Swedish commercial weight loss program called Itrim was evaluated for its effectiveness, and researchers found that participants lost an average of 11 kg after one year. The program, which includes three different diets and group sessions, showed promising results with the most rigorous diet resulting in the greatest weight loss.
A study published in European Heart Journal found that between 30-40% of obese patients are metabolically healthy, exhibiting better cardiorespiratory fitness and a lower mortality risk. Health professionals can use lipid profile, BMI, and fitness to assess the risk for heart or cancer disease in obese individuals.