Articles tagged with Obesity
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Research from Massachusetts General Hospital finds that gastric bypass changes microbial populations in obese mice, leading to weight loss and improved metabolism. Transferring altered microbiota into germ-free mice reproduced the effects of bypass surgery.
Researchers at Harvard University have discovered that drastic changes in the gut microbes of mice occur following gastric bypass surgery, resulting in rapid weight loss. The study suggests that manipulating microbial populations could become a valuable tool to address obesity.
A study published in The American Journal of Clinical Nutrition found that consuming a high-protein breakfast significantly improves appetite control and reduces unhealthy snacking in young adults. Eating a protein-rich breakfast led to increased fullness and reduced brain activity controlling food cravings.
A Cedars-Sinai study suggests that certain microorganisms in the gut may contribute to weight gain by allowing individuals to reap more calories from their food. The study found that people with high concentrations of methane and hydrogen gases in their breath had higher body mass indexes and body fat percentages.
Researchers developed a weight loss program that successfully helped participants with serious mental illnesses, including schizophrenia and bipolar disorder. The program involved exercise classes and individual weight loss guidance, leading to significant weight loss and sustained results.
Research studies found that obesity is associated with longer hospital stays and higher related costs in total knee replacement patients, but not with an overall increase in complication risk. Patients with a BMI of 25-30kg/m2 had the lowest length of hospital stay and direct medical costs.
Genetic factors such as BRCA2 and HOXB13 play a crucial role in predicting high-risk prostate disease. Lifestyle factors including diet, exercise and geographic origin are also risk factors for PCa.
A community-based diabetes prevention program, led by health workers, successfully reduced blood glucose levels and improved insulin sensitivity in overweight participants with prediabetes. The study replicated the results of the Diabetes Prevention Project, demonstrating a significant reduction in diabetes risk.
Researchers at Johns Hopkins have developed a minimally invasive procedure that uses a stent to alleviate symptoms of pseudotumor cerebri by expanding narrowed veins and relieving fluid pressure. The study shows promising results, with 10 out of 12 patients experiencing complete and lasting recovery.
A new University of Illinois study reveals that college-age kids who don't consume at least three servings of dairy daily are three times more likely to develop metabolic syndrome. The researchers found that only one in four young persons met the recommended amount of dairy, leaving three-fourths at risk.
Researchers found a cross-talk between two types of brown fat that helps maintain body temperature and protect against diet-induced obesity. The study's findings may lead to new therapies that increase BAT formation to treat obesity.
A literature review suggests that weight loss can diminish pain, restore function, and quality of life in osteoarthritis patients. Obesity may trigger biomechanical changes contributing to the condition, making weight loss a key treatment option for arthritis and joint pain prevention.
A minimally invasive procedure called gastric artery chemical embolization (GACE) was found to be safe and effective in reducing hunger hormone levels and promoting weight loss in obese patients. After six months, participants experienced significant weight loss, with an average of 45 pounds lost.
A recent study discovered a gene responsible for obesity in mice, and deleting it eliminated obesity even on high-fat diets. The researchers believe this may be replicated in humans using existing technology targeting the specific gene.
A study by Johns Hopkins Medicine found that weight loss benefits the heart health of young obese mice, reversing poor heart function and reducing fat deposits. However, this effect was lost in older mice with longer periods of obesity, highlighting the importance of early weight loss in preventing heart damage.
A large epidemiological study found that increased sugar availability was linked to higher diabetes rates, independent of obesity. The researchers analyzed data from 175 countries and found a 1% increase in diabetes prevalence for every additional 150 calories of sugar per person per day.
Researchers at the University of Michigan are studying how exercise affects lean and obese rats to better understand insulin resistance and muscle glucose uptake. By comparing responses in both groups, they aim to develop more effective treatments for improving health across different populations.
Researchers found that insulin action follows a 24-hour circadian rhythm, with mice becoming insulin-resistant during the day. Mice unable to keep the time of day get stuck in an obesity-prone mode.
The Asia Pacific region is experiencing a creeping epidemic of obesity, with quadrupled rates in China and increased prevalence among countries such as Japan and Australia. Experts attribute the rise to sedentary lifestyles, Westernized diets, and cultural attitudes that prioritize food as a way of showing hospitality.
A recent study found that bariatric surgery does not lower overall healthcare costs in the long term. Instead, it results in higher inpatient costs and lower prescription and office-visit costs. The research analyzed data from over 29,000 patients who underwent bariatric surgery between 2002 and 2008.
A study by William Leonard examines the roles of diet and energy expenditure in contributing to obesity. The research shows that human dietary patterns have evolved over time, with a shift from subsistence to modern lifestyles leading to increased energy imbalances.
A new study reveals that American black newspapers predominantly report on obesity in a negative light, emphasizing individual responsibility rather than socio-economic factors. This framing may discourage African Americans from taking action to address their weight issues.
A study found that obese pregnant women who followed a healthy lifestyle program were more likely to stay within the recommended weight gain limit, with a lower risk of hypertension, preterm delivery, and gestational diabetes. The program included a 1500 kcal/day diet and mild physical activity.
Researchers found that African-American women with pre-pregnancy obesity and excess weight gain during pregnancy are more likely to have macrosomia, or newborns weighing over 4,000 grams. This increased risk is linked to energy accumulation by the fetus from increased maternal glucose concentrations and insulin resistance.
A team of researchers at the University of Michigan's Life Sciences Institute has found that amlexanox, an off-patent drug, can reverse obesity, diabetes, and fatty liver in mice. The study suggests that the drug works by inhibiting two genes involved in metabolic balance, leading to increased metabolism and weight loss.
Researchers at Virginia Tech discovered that Helicobacter pylori, a bacterium blamed for health issues like gastritis and gastric cancer, helps balance the stomach's ecosystem and control body weight and glucose tolerance in mice. The findings suggest that H. pylori may provide important metabolic traits required to combat diabetes.
A study by Johns Hopkins Bloomberg School of Public Health found that physicians who believe overconsumption of food contributes to obesity are more likely to advise patients to modify nutritional habits. The study analyzed data from 500 US primary care physicians and found a significant correlation between physician beliefs and counse...
A USC study finds that progestin-releasing long-acting reversible contraception (LARC) devices may pose a slight negative impact on metabolic markers, raising the risk for type 2 diabetes in healthy, obese reproductive-age women. The research concludes that LARC appears safe but merits further investigation.
Research suggests that being overweight is a risk factor for gum disease, which can lead to chronic inflammation and other health issues. Daily brushing, flossing, and professional cleanings are essential for preventing gum disease and maintaining good oral health.
A new study finds that obesity increases risk of death with age, contradicting earlier research on the 'obesity paradox'. The analysis of over 800,000 adults reveals that obese individuals face a higher risk of mortality as they get older.
Researchers have discovered a trigger that turns muscle stem cells into brown fat, a form of good fat associated with less obesity. The discovery, published in Cell Metabolism, provides hope for a potential obesity treatment using adult skeletal muscle stem cells.
Researchers at University of Bristol identify MC4R as critical regulator of brain's response to obesity, also linked to increased blood pressure and type 2 diabetes. The study reveals a mechanism by which MC4R balances sympathetic and parasympathetic nervous system activity.
Researchers found that physical activity alone does not correlate with obesity or body fat among the Tsimane, suggesting excess food intake may be more responsible for chronic disease. The study also revealed that modernization has little impact on physical activity levels, but women are more likely to be overweight.
A new study from UCLA has identified a possible link between outdoor food ads and a tendency to pack on pounds. The researchers found that the more outdoor advertisements promoting fast food and soft drinks there are in an area, the higher the likelihood that residents are overweight.
Douglas Coleman, a retired Jackson Laboratory scientist, has won the Frontiers of Knowledge Award in Biomedicine from the BBVA Foundation and the King Faisal International Prize in Medicine. His work, alongside Jeffrey Friedman's, revealed chemical and genetic factors involved in appetite control and obesity.
Research finds that exposure to certain plastics and hydrocarbons can cause reproductive diseases and obesity in descendants, leading to epigenetic inheritance. The study identifies nearly 200 molecular markers for exposure and disease, paving the way for diagnostic tools and new therapies.
A UC Irvine study reveals that low-dose exposure to the chemical tributyltin during pregnancy can lead to obesity in offspring and great-grandchildren, affecting gene expression and fat accumulation. The findings suggest permanent effects without subsequent exposure, highlighting the risks of endocrine-disrupting compounds.
Research at the University of Missouri found that certain exercises benefit obese men but not women with Type 2 diabetes. Obese women may require longer or higher-intensity exercise programs to see similar improvements in cardiovascular function.
Research finds widening gap in obesity estimates attributed to biased self-reports of weight. Increasing bias in self-reported weight contributes to underestimation of clinically measured BMIs.
Researchers analyzed data from 1996 to 2008 and found obese drivers were 21-80% more likely to die in collisions than normal-weight peers, with women facing even greater risks. The study suggests car design may need to change to better protect obese occupants.
The Journal of Eating Disorders is an open-access journal publishing research on the science and clinical practice of eating disorders. Recent studies explore internalized weight bias, perfectionism in body dissatisfaction, and cross-cultural aspects of eating disorders.
A landmark study found gastric banding to be an effective long-term strategy for managing obesity, with 78% of patients maintaining significant weight loss after 10-15 years. The procedure has lasting benefits, including improved health and longer lifespan, as well as effective control of type 2 diabetes.
A study found that overweight and obese individuals are gaining weight rapidly in low-and middle-income countries, while those who are severely undernourished are not experiencing similar weight gains. This growing divide may force governments to balance priorities between addressing health issues afflicting the underweight and the obese.
A study led by a Virginia Commonwealth University professor found that nearly 30% of knee-replacement surgery patients gained 5% or more of their body weight over five years. This is significantly higher than the 20% gain rate in comparison group without surgery.
Researchers found no link between dietary patterns and cardiovascular disease, diabetes, or metabolic syndrome in older adults. However, a Western diet was associated with an increased risk of hypertension. The study suggests that overly restrictive diets may not be beneficial for older adults.
Research examines data from multiple studies to better understand how obesity impacts kidney transplant patients. Obese patients experience more adverse outcomes, including wound infections and cardiac disease, leading to poorer health outcomes after surgery.
A new gene has been identified with a key role in obesity and diabetes, regulating fat storage and energy expenditure. The study suggests that blocking this gene could lead to therapies for obesity and related illnesses.
Pregnancies after bariatric surgery are safer than in morbidly obese women, but there are still risks involved. Experts recommend that women should wait at least 12 months before trying for a baby following weight loss surgery.
Obese individuals are more prone to asthma due to the regulation of airway diameter by leptin. Leptin therapy may provide a new treatment option for body weight-associated asthma, with existing drugs targeting parasympathetic signaling already available.
Despite a significant increase in overweight and obese Americans, primary care physicians have decreased weight counseling services, especially for patients with high blood pressure and diabetes. In 2007-2008, only 6.2% of visits included weight counseling, a decline from 1995.
A new study reveals that genetic factors significantly contribute to obesity, with DNA influencing body-fat responses to high-fat, high-sugar diets. The research found that genetics account for up to 80% of the variation in body-fat percentage among mice, suggesting a strong link between DNA and fat gain.
Researchers have demonstrated that obesity aggravates disorders associated with tau protein in mice, contradicting previous assumptions. The study suggests environmental factors contribute to the development of Alzheimer's disease, rather than just metabolic conditions.
Researchers at Joslin Diabetes Center have identified TRIP-Br2 as a major regulator of energy metabolism and fat storage. In mice fed high-fat diets, TRIP-Br2 levels were elevated in visceral fat, leading to increased fat accumulation and decreased energy expenditure.
Sanford-Burnham researchers discover that protein p62 plays a crucial role in balancing metabolism in fat tissue. When p62 is missing, the body's metabolic balance shifts towards 'bad' white fat and away from 'good' brown fat. This finding indicates that p62 could be an attractive target for new therapies aimed at curbing obesity.
A University of Missouri study failed to replicate previous research on the toxic effects of BPA and genistein, two chemicals that have been linked to obesity and type 2 diabetes in humans. The findings suggest that the chemicals may not have the same adverse effects as previously reported, highlighting the need for more reliable data ...
In a large randomized trial, aerobic training was shown to result in greater weight and fat loss compared to resistance training or a combination of both. Aerobic exercise also led to significant reductions in waist circumference and improvements in cardiopulmonary fitness.
A study of nearly 3 million adults found that obesity and higher levels of body mass index (BMI) are associated with a significantly higher risk of death. Conversely, being overweight was found to have a lower risk of death. The researchers suggest possible explanations for these findings, including earlier presentation of heavier pati...
Researchers say targeting extraoral taste receptors in the gut could release hormones that signal fullness, mimicking meal effects and aiding weight loss. Additional studies are needed to identify effective drug targets for obesity treatment.
A new UCSF study examines the role of key molecule PKCγ in regulating the food clock, which is disrupted by irregular eating patterns. The findings have implications for understanding diabetes, obesity, and other metabolic syndromes.
A new study by Johns Hopkins Bloomberg School of Public Health reveals that primary care physicians feel unprepared to address obesity due to inadequate medical education. Despite this, they support additional training and practice-based changes to improve their skills. Key findings include the importance of nutritionists and dietitian...