Articles tagged with Obesity
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Researchers at the University of Alabama, Birmingham have found that mutations in primary cilia can disrupt the functioning of the melanin concentrating hormone receptor, leading to increased appetite and weight gain. This discovery sheds light on the potential link between ciliopathies, such as Bardet-Biedl syndrome, and obesity.
A University of Illinois survey found that Mexican college applicants who were physically active reported more conflict about exercise at home than those who were not. The study suggests that parents' cultural beliefs and attitudes towards physical activity can be a significant barrier to teens' engagement in regular exercise.
A recent study found that resting muscle sympathetic nerve activity (MSNA) is a significant independent predictor of weight-loss outcome in overweight or obese subjects. Successful weight losers demonstrated large increases in nerve activity following a carbohydrate test meal.
A six-month growth hormone replacement study found increased bone formation, muscle mass, and decreased abdominal fat in abdominally obese women. The results suggest growth hormone as a potential treatment for postmenopausal osteoporosis.
Researchers have successfully transplanted immature neurons from healthy mouse embryos into adult mice with a genetic deficiency, restoring leptin signaling and partially normalizing their metabolism. The study demonstrates the potential of neuronal replacement therapy for treating metabolic disorders.
Research by Paul Williams found that certain risk factors, such as lower education level and high meat/low fruit diets, become stronger for those with a higher BMI, contributing to accelerated weight gain. This phenomenon may explain the recent increase in obesity rates in Western societies.
Scripps Research scientists have identified a key gene that plays a crucial role in maintaining metabolic balance. The study found that the melanocortin-3 receptor (MC3R) expressed outside the brain is equally important as its central nervous system counterpart.
A Concordia University study found that 25% of Canadians aged 31 to 50 exceed the safe limit of total calories derived from fats. Individuals who eat well are 20% less likely to be obese, according to the researchers.
A team of scientists, led by Syracuse University chemist Robert Doyle, has successfully delivered the appetite-suppressing hormone PYY into the bloodstream orally using a vitamin B12 vehicle. The study demonstrates the potential for a natural weight loss supplement in the form of chewing gum.
The ASGE and ASMBS have issued a white paper exploring the role of EBTs in treating obesity. EBTs, such as laparoscopic gastric bypass, adjustable gastric banding, and sleeve gastrectomy, may offer patients an outpatient alternative to traditional bariatric procedures.
A new Cornell University review article finds that powerful environmental cues are subconsciously bending willpower every day. Portion size emerged as one of the most powerful links to overeating, with package size playing a significant role.
According to Northwestern University researchers, over 83% of men and 72% of women will be overweight or obese in 2020. The implications of not improving cardiovascular health by 20% could lead to a reversal of declining rates of sickness and death from cardiovascular disease.
Scientists engineer mice to express human enzyme IKKbeta in fat tissue, significantly slowing weight gain and improving metabolism. The study suggests obesity is worse than inflammation for insulin resistance, offering new clues about the connections among obesity, inflammation, and type 2 diabetes.
A primary care-based weight intervention led to a significant weight loss of 10.1 pounds over two years in obese patients. The program, which included lifestyle counseling and meal replacements, also improved cardiovascular disease risk factors.
A Spanish study of 945 adults found that high fish consumption was linked to lower glucose concentrations and a reduced risk of developing diabetes. In contrast, excessive red meat consumption was associated with increased weight gain, obesity, and higher cardiovascular risk.
A study found that consuming dairy foods and higher protein resulted in improved markers of bone formation and reduced markers of bone degradation in overweight premenopausal women. The study showed that a diet with a high proportion of dairy foods and higher than recommended protein intake was associated with improved bone health.
A pilot study of 31 obese people with gum disease found that those who underwent gastric bypass surgery had better periodontal outcomes than those who did not. The researchers believe that removing excess fat cells may help reduce inflammation and improve the body's response to treatment.
Researchers developed a new anti-obesity medication that targets fat cells, reducing body weight and abdominal circumference in rhesus monkeys. The treatment showed promise in improving insulin resistance and reversing metabolic syndrome, potentially providing a non-surgical solution to obesity.
A new study suggests that migrant South Asians should be classified as obese with a BMI between 23-28 kg/m2, indicating a higher risk of developing diabetes and cardiovascular disease. The conventional definition of obesity may need to be lowered for this population to detect equivalent levels of cardiovascular risk.
Researchers found that slow eaters consumed significantly fewer calories than fast eaters, with whole grains taking longer to digest. The study also showed a strong association between eating rate and body mass index (BMI), suggesting that slower eating may be related to lower energy needs.
A web-based intervention aimed at promoting healthy eating and physical activity among adolescents was found to have no long-term effects on weight gain, but did show positive short-term changes in dietary behavior. The study evaluated the effectiveness of the FATaintPHAT intervention over two years, finding it ineffective in reducing ...
A Mediterranean diet combined with physical activity has been shown to improve some symptoms of sleep apnea, including reduced number of disturbances during REM sleep. This study found a greater adherence to the calorie-restricted diet and increased physical activity in the Mediterranean diet group compared to the prudent diet group.
Researchers find that toxic byproducts from unsaturated fat breakdown lead to severe inflammation, cell death, and multi-system organ failure in obese acute pancreatitis patients. The study provides new insight into how fat can induce complications after sudden inflammatory illnesses.
A study published in Environmental Health Perspectives found that replacing short auto trips with bicycle trips can save an estimated $7 billion per year by reducing mortality and healthcare costs. Biking also improves local air quality and reduces greenhouse gas emissions.
A clinical trial of resveratrol supplements has shown significant metabolic shifts in obese men, comparable to calorie restriction. The study found improved measures of metabolism, lower blood sugar levels, and a drop in blood pressure, with no apparent side effects.
Overweight teenagers in Philadelphia report wanting to lose weight, but their actions are more hindrance than help. The study found that obese teens are more likely to smoke and consume soda daily, despite exercising regularly.
A new study found that middle-income earners prefer fast-food dining due to its affordability and convenience. The research suggests that policymakers should look beyond restaurant type when addressing the obesity epidemic.
Researchers find that providing obese adolescents with a daily dose of 4,000 IUs of vitamin D3 improves their vitamin D status. The study suggests that obese adolescents require higher doses due to reduced absorption in fat stores.
A new study led by Brown University found that vitamin D does not confer benefits against mortality in postmenopausal women, contrary to previous beliefs. The study controlled for key health factors like abdominal obesity and found no association between high or low levels of vitamin D and reduced risk of death.
Researchers found that specific microRNAs are up-regulated in obese individuals with healthy periodontium and non-obese subjects with periodontal disease. The study suggests microRNA modulation may play a role in modulating inflammatory pathways within periodontal tissues.
A Group Health Research Institute study found that obesity is associated with higher health care costs, but not due to co-occurring depression. Similarly, depression is linked to increased costs, but not because of co-occurring obesity. The study's findings have significant economic implications for the general population.
A new study by University of North Carolina Health Care reveals that obesity impairs the immune system's ability to fight flu viruses. The research found that obese individuals experience a decline in antibody levels and defective CD8+ T cells after receiving the annual flu shot, making them more susceptible to flu illness.
A new study links obesity to increased airway hyperresponsiveness, indicating that obesity is a risk factor for asthma. Meanwhile, specialists' awareness of asthma guidelines does not necessarily lead to better adherence and implementation of management practices.
A recent study found that peri- and postmenopausal women in Spain have a deficient intake of vitamin D, which increases the risk of health problems. The average total intake was just 39% of the RDA for women of this age group.
A recent study published in Nutrición Hospitalaria found that obese women, particularly those with morbid obesity, develop breast cancer at a significantly earlier age. The researchers discovered that the age at first menstruation is a key factor in determining the development and diagnosis of breast cancer.
Researchers found that consuming more protein leads to increased energy intake and snacking, but only up to a certain threshold. The study suggests proper protein intake can help moderate energy consumption and reduce obesity risk in lean individuals.
Children tend to dislike peers with undesirable characteristics more if they attribute fault for the trait rather than assuming they've tried to change it. However, when a peer has attempted to overcome an issue, kids are more accepting and even positive towards them.
Scientists at UC Metabolic Diseases Institute discover that targeted inhibition of CB1 receptor can increase calorie burning in brown adipose tissue, leading to reduced body weight and blood glucose. Further study aims to find a safer and more effective drug strategy for glucose regulation and weight loss.
A study published in PLOS Genetics identified a gene and protein involved in regulating insulin secretion in obese mice. The researchers found that a single amino acid difference in the tomosyn-2 protein destabilizes it, leading to an insufficient insulin response and diabetes susceptibility.
Scientists at Sanford-Burnham discovered that orexin activates calorie-burning brown fat in mice, suggesting potential for new obesity treatments. The hormone is associated with increased energy expenditure and weight loss.
Obese mice fed green tea supplement gained weight 45% more slowly than control group, suggesting EGCG limits fat absorption and enhances fat use. Green tea did not suppress appetite and a person would need to drink ten cups daily to match study amount.
Scientists at Gladstone Institutes have identified CCT enzyme as a key regulator in fat storage. The research suggests new directions for treating excess fat storage and obesity. By understanding how the body stores fat safely, researchers can explore new treatments for conditions like heart disease and type 2 diabetes.
A newly published Cochrane systematic review reveals that the transtheoretical model stages of change (TTM SOC) method is ineffective in achieving significant weight loss. The study found that TTM SOC resulted in only 2kg or less weight loss, and no conclusive evidence of sustained weight loss was observed.
A recent study published in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found a link between shift work and increased cortisol levels. This association was discovered in individuals working shifts at a young age and may contribute to cardiovascular risk.
Researchers at the University of California San Diego have identified unsaturated and polyunsaturated fats from plants and cold-water fish as beneficial for health. These fats block JNK activation by saturated fatty acids, which are linked to adverse health effects.
A recent study by researchers at the University of California, Berkeley, suggests that embarrassment can be a positive trait, fostering trust and cooperation in everyday life. Subjects who were more easily embarrassed reported higher levels of monogamy and generosity, indicating a stronger tendency to affiliate with others.
Scientists at Karolinska Institutet found that fat cells in overweight people have a higher capacity for storing fats but a lower capacity for ridding themselves of them. This can lead to an accumulation of triglycerides and cholesterol in the blood, increasing the risk of metabolic diseases.
A new study finds that central obesity is a risk factor for asthma in adults, with those who are both centrally obese and overall obese being at highest risk. Researchers followed over 23,000 adults without asthma for 11 years to investigate the link between belly fat and lung disease.
Researchers at Joslin Diabetes Center have identified two molecular pathways that activate brown fat, a type of fat that burns energy rather than storing it. The study provides new opportunities to stimulate brown fat growth, which could lead to the development of treatments for obesity and diabetes.
Research reveals that a high-salt diet and obesity trigger abnormal activation of the Rac1 protein in kidney cells, leading to increased blood pressure. This finding offers a potential new therapeutic target for treating salt-sensitive hypertension.
A new study from the University of New Hampshire finds that overweight older women have less leg strength and power than normal-weight counterparts, which can lead to increased disability and loss of independence. The study suggests that maintaining a normal weight and improving strength through exercise may help mitigate this risk.
Researchers found that obese individuals' brains respond less to visual cues of high-calorie foods due to impaired glucose regulation. In contrast, non-obese individuals with normal glucose levels exhibit a stronger desire for these foods when triggered by food cues.
Research found that engaging in one healthy lifestyle behavior can decrease heart failure risk, while each additional behavior further reduces the risk. Key findings include: regular physical activity and a diet rich in vegetables lowering risk by 21-33% and 26-27%, respectively.
A commercial weight loss programme, Weight Watchers, has been shown to be effective in reducing weight and improving health outcomes for overweight adults. Participants who received the programme lost around twice as much weight as those receiving standard care over 12 months.
African American women with higher BMI levels are at increased risk of death, according to a new study. A larger waist size was also associated with a higher risk of death among non-obese women, highlighting the importance of maintaining a healthy weight and reducing waist size.
A UK study reveals that long-term complications after bariatric surgery should be thoroughly assessed and investigated. A Finnish study finds that bariatric surgery is a more cost-effective way to treat morbid obesity than non-operative care, with reduced healthcare costs and improved quality of life.
Researchers at Ohio State University Medical Center found a biological switch that converts white fat to brown fat, leading to reduced abdominal fat mass and improved metabolism. The discovery uses environmental enrichment to activate a nerve and biochemical pathway that stimulates the transformation.
A recent study found that heavier women have fewer hot flashes than their leaner counterparts after menopause. The inverse association between body size and hot flashes was observed only among older women, suggesting that age plays a significant role in this relationship.
Researchers found that elevating free radical levels suppresses appetite in obese mice by activating satiety-promoting neurons. This process is driven by hormones leptin and glucose, which signal the brain to modulate food intake.
Researchers have identified a potential new target for treating obesity by studying the molecular control of appetite in mice. Nutrient intake triggers the secretion of uroguanylin, which is then converted to uroguanylin and binds to GUCY2C receptors, leading to decreased food intake.