Articles tagged with Obesity
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A new web-based bodyweight simulation model simulates physiological differences between people based on sex, age, height, and weight. It provides a rough dieting rule for typical overweight adults: every 10 calories per day reduction in energy intake results in about 1 pound of weight loss over 3 years.
Scientists at Thomas Jefferson University found that silencing the hormone receptor GCC affects appetite in mice, inducing obesity, while mice expressing the receptor know when to stop eating. This new neural-gut axis provides a potential therapeutic target for controlling appetite and obesity.
The study predicts a significant increase in obesity rates in the US and UK, with an estimated 65 million additional obese adults in the US and 11 million more in the UK by 2030. This would lead to increased healthcare costs and a higher risk of chronic diseases such as diabetes, coronary heart disease, and cancer.
The Lancet editorial emphasizes the need for a Framework Convention on Obesity Control to address the growing epidemic. It highlights the importance of accurate monitoring and evaluation, system-wide approaches, and government leadership in combating obesity.
A study by UC Davis researchers found biological indicators of toxic fat cells in those with metabolic syndrome, which may lead to diabetes and cardiovascular disease. The discovery supports a new high-risk obesity category for these conditions.
A breakthrough discovery identifies a key gene, SIRT3, that exacerbates the development of metabolic syndrome, a condition linked to obesity, high blood pressure, and insulin resistance. The study suggests that increasing SIRT3 activity could help alleviate symptoms and develop new treatments for this growing health concern.
A new study by Arizona State University researchers found that women often underestimate the weight of their friends' and family members' opinions on their weight. Despite having supportive loved ones, women are vulnerable to fat stigma due to pervasive mass media messages.
A new tool, the Edmonton Obesity Staging System (EOSS), predicts mortality risk in overweight and obese individuals with greater accuracy than current methods. The study found that higher EOSS scores were associated with increased mortality risk, even after adjusting for BMI and metabolic syndrome.
Researchers at the University of Adelaide have found a direct link between obesity and electrical abnormalities in the heart muscle, leading to atrial fibrillation. Obesity can increase blood pressure and put strain on the heart, increasing the risk of developing this common heart rhythm disorder.
A new study from Loma Linda University found that excess body fat in elderly individuals decreases life expectancy. Maintaining a normal weight between 18.5 and 24.9 is considered ideal, while overweight and obesity are associated with increased risk of mortality.
A new study reveals that weight loss of 5% improves erectile function, sexual desire, and lowers urinary tract symptoms in obese men with type 2 diabetes. The study found that modest weight loss resulted in rapid reversal of sexual and urinary problems within 8 weeks.
Scientists at Joslin Diabetes Center have discovered a new connection between obesity and insulin resistance through altered protein splicing. The study suggests that changes in RNA splicing proteins may contribute to the development of type 2 diabetes, offering potential targets for novel diabetes drugs.
Researchers propose a new counseling model that views obesity as a result of neurobehavioral processes, rather than personal choice or willpower. The approach highlights three key factors: food reward, inhibitory control, and time discounting, and recommends strategies to help patients overcome these challenges.
A new school-based obesity prevention curriculum has been shown to significantly reduce medical costs associated with obesity and eating disorders. The program, Planet Health, was found to prevent 1 case of bulimia nervosa among girls aged 13-17 in each participating school, resulting in an estimated $34,000 in savings per girl.
A study found that high blood pressure, diabetes, smoking, and obesity in middle age can lead to brain shrinkage and decreased cognitive function over time. The study involved 1,352 participants without dementia and found associations between these risk factors and white matter hyperintensities and executive function decline.
A study published in PLOS Biology found that a defect in brain glucose sensing contributes to obesity, while correction of this defect can treat the condition. The researchers discovered a novel role for hypoxia-inducible factor (HIF) in hypothalamic glucose sensing and whole-body energy balance regulation.
A study by Arizona State University researchers aims to understand the connection between gut microbiota and obesity treatment outcomes. The research focuses on two popular obesity treatments: gastric bypass surgery, which has been shown to alter gut microbial populations.
An analysis of patient safety incident data reveals that the NHS is poorly equipped to handle obese patients, with common themes including inadequate staffing, specially adapted equipment, and surgical errors. Most incidents resulted in little or no harm, but severe cases were reported.
A recent study found that increased body mass index (BMI) is an independent predictor of clinical decompensation in patients with compensated cirrhosis. The researchers suggest that weight reduction may improve patient outcomes and that measures to reduce BMI could improve the prognosis for patients with advanced liver disease.
Researchers at Wayne State University are investigating the link between toxicity of fatty acids and obesity-diabetes connection. They're developing sensors to visualize fatty acid production and signaling in live cells, aiming to create new anti-obesity therapeutics.
Researchers found that stress testing with MPI was unnecessary for most patients undergoing pre-operative workup for bariatric surgery. The incidence of abnormal findings on MPI was only 5%, and perioperative cardiovascular events were extremely low despite high risk factors for coronary artery disease.
A recent study suggests that seven potentially modifiable risk factors, including smoking and physical inactivity, contribute to an estimated half of all Alzheimer's disease cases worldwide. By reducing these risk factors by 25%, up to 3 million cases of AD could be prevented globally.
A study found that obese and non-obese women experienced reduced calorie consumption when exposed to the same foods in different ways, suggesting meal monotony can lead to decreased caloric intake. The results support the idea that reducing food variety may be an effective strategy for weight loss.
A study of 40 fast-food and sit-down restaurants found that overall stated calories were accurate, but individual foods had significant inaccuracies. Foods with lower calorie contents were often understated, while those with higher calorie contents were overstated.
Researchers at the University of Pennsylvania School of Medicine have identified a genetic basis for muscle endurance in animal study. The study found that mice lacking a specific gene exhibit increased endurance and fatigue resistance, similar to elite athletes.
Researchers found that women who attended weekly group sessions to improve their body image lost more weight than those receiving general health information. The study showed a strong correlation between improved body image and positive changes in eating behavior, highlighting the importance of addressing body image issues in weight lo...
A new study found that bariatric surgery is a cost-effective treatment option for all obese patients, with significant savings in medical costs over lifetime. The analysis suggests that the procedure should be universally available to all obese people, making it a good value and a potential game-changer in obesity treatment.
Research suggests that dietary supplementation with molasses extract can reduce body weight and fat levels in mice. After 12 weeks on a high-fat diet supplemented with 4% molasses extract, mice had lower body weight, reduced body fat, and decreased leptin levels.
Research demonstrates that higher-protein meals lead to greater satiety throughout the day, reducing hunger and increasing fullness. Higher-protein diets are associated with reduced calorie consumption and support muscle maintenance, making them an essential component of a healthy meal pattern.
Researchers found that obese patients developed respiratory insufficiency (RI) and adult respiratory distress syndrome (ARDS) less frequently, with lower in-hospital mortality rates. Fatty tissue may act as a sink for inflammatory proteins, neutralizing them and reducing the inflammatory process.
A recent study found that gum disease can increase the time it takes for women to conceive, with non-Caucasian women facing a greater risk. The study, which followed over 3,700 pregnant women, revealed that those with gum disease took an average of seven months to become pregnant, compared to five months for those without gum disease.
Researchers found that reducing TGF-beta protein actions in mice converted white fat into brown fat-like cells with increased mitochondria, leading to calorie burning and reduced obesity. This discovery identifies a potential new approach to treating obesity and Type 2 diabetes.
A study by Boston University School of Medicine shows that the quality of fat tissue, not just its quantity, contributes to inflammation and vascular disease in obese individuals. The research identified that 30% of obese subjects demonstrated reduced fat inflammation, less insulin resistance, and similar vascular function.
A study found that poor pre-pregnancy diet can lead to reduced birth weights, catch-up growth after weaning, and increased insulin sensitivity in offspring. These effects combined increase the risk of developing type II diabetes and obesity later in life.
A University of Illinois study found that obese dieters face challenges in losing weight due to changes in their brain chemistry, triggered by a fast or near-fast diet. This can lead to reduced motivation and depression-like behaviors.
Researchers at UTHealth are exploring the link between Adenovirus-36 and obesity, with a focus on firefighters who are more likely to be overweight or obese. The study aims to design health and wellness strategies for this high-risk population.
A new study suggests that magical thinking can help consumers cope with the stress of trying to lose weight by invoking mystical forces. Consumers often describe weight loss as being influenced by mysterious forces, such as a body that 'conspires' against them or food that 'seduces' them.
A study of 552 Maine high school students found no correlation between the presence of fast food stores near schools and their risk of being overweight. Despite high consumption of sweetened drinks and fast food among students, proximity to unhealthy food retailers had little impact on their weight status.
A recent study published in JAMA found that bariatric surgery among older, severely obese patients is not associated with reduced mortality. The study examined the long-term survival of high-risk patients who underwent bariatric surgery and compared them to nonsurgical controls.
A Finnish twin study suggests that adaptation of fat cell membranes to obesity may play a key role in early stages of inflammatory disorders. The study found that obese individuals have higher amounts of certain lipids in their adipose tissues, which may help preserve membrane function as cells expand.
A new animal study finds that a high-fat diet can cause inflammation and injury to brain cells in the hypothalamus, leading to weight gain. The research suggests that this neuronal injury may be permanent, contributing to the difficulty of achieving sustained weight loss in obese individuals.
A Finnish twin study found that obese individuals have higher amounts of polyunsaturated fatty acids in their adipose tissues than non-obese twins. The researchers suggest that this adaptation helps preserve membrane function as the cells expand, but breaks down in morbidly obese individuals.
A new study found that overweight men are at a significantly higher risk of developing cirrhosis of the liver compared to those who drink heavily. The research followed 855 men for up to 40 years and discovered that both excess weight and high levels of blood fats increased liver damage, while alcohol's link was not statistically proven.
Researchers have found that insulin directly affects the brain's reward circuitry, leading to increased food intake and obesity in mice. This study suggests that insulin resistance may contribute to the difficulty in managing weight loss. Further research is needed to understand the clinical implications of these findings.
A new Ohio University study found that mice who switched between a high-fat and low-fat diet lived about 25 percent longer and had better blood glucose levels than obese animals. The yo-yo dieters' lifespan was comparable to that of a control group steadily fed a low-fat diet.
A new study found a significant correlation between high BMI and decreased aromatase availability in the brains of overweight subjects. This suggests that low estrogen levels may lead to reduced control over appetite and food intake, resulting in weight gain.
A recent study comparing yo-yo dieting to lifelong obesity found that weight fluctuations are better for health than remaining obese. Mice on a yo-yo diet regimen lived nearly 35% longer and had improved health measures compared to those on a high-fat diet.
A new therapeutic vaccine targets ghrelin to suppress appetite and increase energy expenditure in mice, reducing food intake by up to 82% after a single vaccination. The study suggests an alternate treatment approach for obesity that can be used in combination with diet and exercise.
A study of 75 obese men found that bariatric surgery can reverse low testosterone levels and symptoms of male sexual dysfunction. After weight loss, testosterone levels increased significantly, indicating a potential causal relationship between obesity and low testosterone.
Women with obesity before and after diagnosis have a higher risk of dying from breast cancer. Obesity is strongly linked to death due to breast cancer, particularly in estrogen receptor-positive cases.
Researchers at Johns Hopkins Medicine found that low-carb diets with higher fat content do not pose immediate risks to vascular health. Obese individuals who followed a low-carb diet showed no adverse changes in key measures of arterial health.
A national survey of nearly 4,000 Americans found that obesity is associated with better health-related quality of life for black men and worse outcomes for black women. The study, published in Quality of Life Research, used comprehensive telephone interviews to assess cognition, vision, speech, hearing, physical activity, pain, mobili...
Recent research review finds no difference in metabolic impact between HFCS and sucrose, contradicting previous media claims. Despite declining HFCS consumption, US obesity and diabetes rates continue to rise.
Researchers found that women who gained more than the recommended weight during pregnancy were three times as likely to be overweight or obese. Regular monitoring of weight in pregnancy may need to be reconsidered to prevent these health problems.
A new study from Johns Hopkins Medicine reveals that obese patients undergoing colon surgery are 60% more likely to develop costly surgical-site infections. These infections result in extended hospital stays, increased costs of $17,000 per patient, and a three-times greater risk of hospital readmission.
Researchers found that add-on diabetes drugs for patients with uncontrolled diabetes on metformin and sulfonylurea have no clear between-drug differences. High-seelenium yeast supplements slightly reduced cholesterol levels but increased the risk of harm, particularly in countries with adequate selenium intake. Obesity is linked to fun...
A study published in Archives of Surgery found that obese patients are at a significantly higher risk of developing surgical site infections after colectomy. The study also showed that these infections result in increased costs, lengthier hospital stays, and a higher rate of hospital readmissions. As pay-for-performance models penalize...
Men who are overweight or obese face a three-fold increased risk of cancer progression and more than a three-fold increased risk of metastases compared to normal-weight men. Obesity is linked to poorer outcomes in prostate cancer patients, regardless of treatment.
A study by Salk Institute scientists reveals that insulin activates a factor called SIK3, which promotes lipid storage during daytime feeding hours by blocking fat breakdown programs. This link between glucose metabolism and lipid storage has potential applications in treating metabolic conditions such as obesity and type II diabetes.
A study by Massachusetts General Hospital found that mild obesity, measured by body mass index, was associated with longer survival rates among ALS patients. Patients who were mildly obese outlived those of normal weight, underweight, or even overweight.