Articles tagged with Obesity
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Researchers at Harvard School of Dental Medicine found that blocking the Klotho protein function in obese mice with high blood sugar levels led to lean mice with reduced blood sugar levels. Additionally, mice without Klotho function gained no body weight after eating a high-fat diet.
Researchers identified a 'diabetes belt' of 644 counties in 15 southeastern states with high prevalence rates, linked to sedentary lifestyle, obesity, and non-modifiable factors. Community design changes can promote physical activity and healthy lifestyles to reduce diabetes risk.
A study of 143 overweight adolescents found those with risk factors like insulin resistance and low HDL cholesterol have less bone mass than their peers. The study suggests that increasing vigorous physical activity can help improve bone mass and reduce the risk of diabetes and heart disease.
A study funded by a $700,000 grant from the National Trauma Institute aims to improve blood-clot prevention medication dosing for critically ill or obese trauma patients. TEG technology will be used to guide physicians in determining the optimal dose of Lovenox.
A new study from Purdue University found that weight discrimination has a direct impact on the physical health of obese individuals, contributing to stress and declining functional abilities. Around 33% of severely obese people in the US report facing discriminatory experiences, which internalize prejudice and stigma.
A study published in Social Psychology Quarterly found that weight discrimination contributes to stress and a decline in functional abilities among severely obese individuals. Around a third of those who are severely obese report facing discriminatory experiences.
Researchers at the University of Pennsylvania identified the neurological and cellular signaling mechanisms that contribute to satiety and body-weight loss. They found that GLP-1 drugs target the nucleus tractus solitarius, which regulates food intake suppression.
Researchers found lower potassium levels associated with higher diabetes risk in African-Americans, who are twice as likely to develop type 2 diabetes. Increasing potassium levels through diet or supplements could potentially prevent the most common form of diabetes.
A study found that binge eaters experience a spike in dopamine levels when exposed to their favorite foods, triggering a desire for more. This neurological response is distinct from other obese individuals who do not exhibit this reaction.
A recent study found that lifestyle intervention, including nutrition and physical activity components, is necessary to maintain or lose weight. Clinicians can effectively prevent further weight gain by providing guidance on healthy habits, leading to improved health status in overweight patients.
Researchers developed an intervention to help pregnant women control their weight, with normal-weight women more likely to stay at a healthy weight. The program increased the chance of returning to pre-pregnancy weight six months after delivery, but had limited success for obese or overweight women during pregnancy.
A new genetic discovery suggests that the loss of function in a human-specific gene called CMAH may contribute to the development of Type 2 diabetes. The study found that mice with this gene mutation developed insulin resistance and pancreatic beta cell failure, leading to decreased insulin production and impaired blood glucose control.
A large proportion of Asians are underweight, but research found that those with a BMI in the range of 22.6 to 27.5 had the lowest risk of death, while severely underweight individuals were more than twice as likely to die.
Researchers found that obese individuals with early-onset knee osteoarthritis who underwent weight loss via bariatric surgery experienced significant improvements in knee pain, stiffness, and physical function. Weight loss also improved quality of life and activities of daily living.
A recent study published by Hospital for Special Surgery found that knee replacement surgeries take significantly longer and cost more for overweight patients. The researchers analyzed data from 454 patients and found that as body mass index increased, so did the time it took to perform all parts of the surgery.
Patients who undergo elective orthopedic surgeries at high-volume hospitals have better surgical outcomes and fewer complications than those at local hospitals. Regionalizers, or patients traveling to regional high-volume hospitals, tend to be younger, white, male, and have private insurance.
A study published in Annals of Internal Medicine found that obesity and knee osteoarthritis result in the loss of approximately 86 million healthy years of life among US adults aged 50-84. This loss disproportionately affects Black and Hispanic women, highlighting the need for targeted interventions to address these conditions.
New research reveals obesity significantly impacts knee pain and function, but also improves with weight loss via bariatric surgery. Studies find increased risk of complications after hip and knee replacement surgery for super-obese patients, emphasizing the importance of weight management in treating knee arthritis.
Researchers found that obesity reduces duration and quality of life by 12 percent, while knee osteoarthritis has a similar impact. A new guideline also recommends targeted prevention and treatment strategies for patients with specific characteristics, such as age, race, and functional status.
A study of 3,939 participants found that obesity was associated with higher eye pressure and a lower risk of open-angle glaucoma in women. The authors suggest that high estrogen levels and hormone therapy may be protective against open-angle glaucoma in obese women.
Research found obesity independently increases risk of fatal coronary heart disease, even after adjusting for other risk factors. The study tracked over 6,000 middle-aged men with high cholesterol and found a significant increase in mortality rates among obese individuals.
A comprehensive review of fructose consumption found no association between fructose and increased food intake or body weight. The study concluded that normal amounts of fructose do not contribute to hyperlipidemia or obesity in either healthy or overweight individuals.
A new clinical trial at NewYork-Presbyterian Hospital/Weill Cornell Medical Center is testing whether surgery can control Type 2 diabetes as effectively as medical treatment. The study enrolls 50 patients with Type 2 diabetes, comparing gastric bypass to conventional medical therapy and lifestyle modifications.
Acute ischemic stroke hospitalizations have declined among middle-aged and older individuals, but risen among those under 35, according to a study by the CDC. The rate of decline was greatest for girls aged 0-4, with a 51% decrease in hospitalizations.
The prevalence of obesity has nearly doubled globally, with women more likely to be obese than men. Meanwhile, high-income countries have shown impressive reductions in mean blood pressure and cholesterol levels, with some countries performing better than others.
The study reveals that global obesity rates have nearly doubled since 1980, with women more likely to be obese than men. Average levels of total blood cholesterol fell in Western countries, but increased in East and Southeast Asia and the Pacific region. High-income countries achieved large reductions in uncontrolled hypertension.
A study by Kaiser Permanente Center for Health Research found that obese women are more likely to report pain with mammograms, while women under 60 may avoid the test due to being too busy. The study also identified other barriers to breast cancer screening, including lower household income and shorter health insurance coverage.
A five-year study of 288 participants found that a combination of physical activity and weight loss improved mobility by 5-20% in older, obese adults. This counteracts the common belief that weight loss is unhealthy for older adults. Community-based programs can effectively provide seniors with poor mobility
Research suggests that reduced exposure to seasonal cold may contribute to rises in obesity due to minimized energy expenditure and reduced body heat production. Increased indoor temperatures may also lead to a loss of brown fat, reducing the body's capacity to burn energy.
Fat is linked to distinct DNA chemical changes, which may help explain why obesity increases the risk of chronic diseases like cardiovascular disease and diabetes. The study identified two genes, UBASH3A and TRIM3, with altered methylation patterns in obese individuals.
Researchers discover that selective activation of nonclassical ER-alpha signaling may help reduce postmenopausal obesity risk by normalizing energy balance. The study found that this type of estrogen signaling is crucial for regulating body weight and preventing metabolic disorders.
A study by UTMB researchers reveals a significant increase in hypertension prevalence among older Mexican-Americans, with higher rates among those with diabetes and obesity. The study highlights the need for targeted interventions to address these factors and improve hypertension management in this growing population.
Researchers at Johns Hopkins Bloomberg School of Public Health found that black obese patients receive less weight-related counseling than white obese patients, regardless of the doctor's race. This disparity is particularly concerning given the increased risk of chronic diseases associated with obesity among blacks in the US.
A new study reveals that individuals with high leptin and low ghrelin levels are more likely to regain weight after dieting. Researchers analyzed the role of hormones in weight recovery and found a significant association between plasma levels of ghrelin, leptin, and insulin.
A recent study published in Obesity found that young adults with social connections to overweight friends and family members are more likely to have higher weight status. Researchers also discovered that these individuals who had close relationships with people trying to lose weight themselves were more motivated to do the same.
Researchers discovered nuclear receptors that may prevent cancer progression and regulate energy homeostasis. The findings suggest ERbeta has growth-suppressive effects in colon cancer cells and regulates Brown Adipose Tissue activity to control energy expenditure.
A Spanish study found alarmingly high cardiovascular risk factors in a random selection of 2,270 adults, with low education levels linked to increased risk. The researchers also discovered strong links between smoking, obesity, abdominal obesity, and high cholesterol levels.
A study found that deaths from cirrhosis shifted from higher to lower social classes between the early and late 20th centuries. The authors suggest lifestyle changes, including dietary habits and drinking patterns, may have played a role in this shift.
Women undergoing gastric band surgery reported significant improvements in urinary function and quality of life, while men experienced worsening erectile function. The study highlights the need for further research into the effects of weight loss surgery on urinary and sexual function.
Research analyzing California hospital data found extreme obesity significantly increased risk of death from 2009 H1N1. Half of hospitalized patients over 20 were obese, with nearly three-fold increased odds of death compared to non-obese counterparts.
Researchers found a link between family history of alcoholism and increased risk of obesity, with women being more affected. The association may be due to the environment, particularly the availability of high-calorie, hyper-palatable foods that stimulate the brain's reward centers.
A new Concordia University study published in The Physician and Sportsmedicine found that obese people are more likely to report exercise-induced asthma. This link may be an important factor in the management of asthma sufferers, particularly those with severe or persistent conditions.
A new study reveals that moderately and morbidly obese drivers face significantly higher risks of death and non-survival in severe auto accidents. The research found that underweight and normal-weight drivers also had a higher risk of dying from severe crashes compared to slightly overweight drivers.
A new study reveals that the UK's richest and poorest continue to experience significant health disparities, with lower-income groups facing higher rates of kidney disease, diabetes, obesity, and smoking. The study highlights the need for continued efforts to address these inequalities and improve public health outcomes.
Researchers discovered a genetic link between the gene CRTC3 and obesity. Mice lacking the gene were protected from weight gain on high-fat diets, suggesting that increased brown fat cells may control obesity. Human studies also found a higher incidence of obesity in individuals with an active version of the gene.
Research shows that deleting the ghrelin receptor but not the protein itself boosts the body's fat-burning thermostat in aging mice. This results in thinner mice with lower circulating lipids and increased heat production.
A new study found that imposing higher taxes on sodas and sweetened drinks would generate significant revenue but result in only minor weight loss for most households. The tax's impact varies by household income, with middle-income groups experiencing the largest reductions in calories and weight.
A retrospective study found that obese women with estrogen receptor-positive/HER2-negative breast cancer experienced significantly worse disease-free and overall survival rates compared to non-obese patients. Obesity was not associated with poorer outcomes in HER2-positive or triple-negative breast cancer subtypes.
A new study found that parents have a limited impact on their children's eating habits, with complex factors like schools and peer influence playing a significant role. Researchers analyzed worldwide studies to conclude that correlations between parent-child dietary intakes have become weaker over time.
A recent NIH study found that a body mass index (BMI) between 20.0 and 24.9 is linked to the lowest risk of death in healthy, non-smoking adults. For individuals who are overweight or obese, the risks of death increase dramatically, with certain BMI ranges associated with significantly higher mortality rates.
A study presented at the Radiological Society of North America found that excessive internal abdominal fat may harm bone health in women. Research revealed that women with more visceral fat had increased bone marrow fat and decreased bone mineral density.
A recent study has found that individuals with obstructive sleep apnea are more prone to developing aggressive atherosclerosis, putting them at risk for impaired blood flow and cardiovascular events. The study used coronary CT angiography to reveal significantly higher prevalence of non-calcified and mixed plaque in OSA patients.
Researchers have identified DNA variants in two nervous system genes associated with an excessively high BMI, providing new insights into the genetics of obesity. The study used a novel approach to link rare and common regulatory variants to extreme obesity.
A new study published in the New England Journal of Medicine found that a diet high in protein and low-Glycemic Index (GI) foods can help prevent weight regain. The study, which involved 772 European families, showed that those who followed a high-protein, low-GI diet had less weight regain than those on other diets.
Researchers found a high rate of weight gain in animal populations, despite varying diets and activity levels. The study suggests that alternative causes, such as epigenetics, may contribute to the obesity epidemic.
A study using fat yet muscular mice aims to understand how more muscle can reduce cardiovascular risk in obese individuals. The research suggests that increased muscle mass improves blood vessel function, glucose disposal, and heart health.
A new study from Harvard School of Public Health finds that high body mass index (BMI) is primarily a problem among wealthy women in developing countries. The study analyzed data from 54 low- to middle-income countries and found an association between BMI and wealth, with richer women more likely to be overweight.
Gökhan S. Hotamisligil, a Harvard expert on inflammation and obesity, received the 2010 Naomi Berrie Award from Columbia University Medical Center. His work focuses on the molecular basis of links between obesity, diabetes, and heart disease.
A recent study found that patients with more intra-abdominal fat are at higher risk of complications following major liver surgery, including longer hospital stays and increased mortality rates. However, body mass index (BMI) was not associated with these risks, highlighting the importance of using alternative measures to assess obesity.
Researchers found that hormone therapy has no effect on prostate size in middle-aged men, while a study on presumed consent policies suggests it may increase deceased kidney donation rates but lower living donor rates. Additionally, high co-pay costs are linked to increased prescription abandonment rates, highlighting the need for affo...