Articles tagged with Obesity
A new study by the American Society of Nephrology found that ramipril lowers the risk of kidney disease progression in all weight groups, but shows a significant reduction in obese patients. Obese patients with kidney disease progress more quickly towards renal failure compared to non-obese patients.
Researchers found that bariatric surgery significantly improved glycemic control in obese patients with type 2 diabetes, even before significant weight loss occurred. The study suggests that biochemical and hormonal changes related to branched-chain amino acids may play a key role in this improvement.
Consumers tend to eat more indulgent food after seeing someone who is overweight, according to a study published in the Journal of Consumer Research. Thinking about personal health goals and reminding oneself of the link between eating and weight problems can help people avoid overindulging.
Researchers at Albert Einstein College of Medicine found a link between a brain molecule, TXNIP, and the development of obesity and type 2 diabetes. Elevated levels of TXNIP in nerve cells contribute to energy imbalance, decreased physical activity, and impaired glucose tolerance.
Researchers found obese patients with metabolic syndrome and high blood pressure are at substantial risk for cardiac, pulmonary, and neurologic complications. The study provides a simple way to identify patients who may face higher risks following surgery.
A new Purdue University study reveals that people who experience discrimination are more likely to gain weight and develop obesity-related health issues. The research found that males tend to be more affected by discrimination than females, with a higher increase in waist circumference over time.
Researchers have found that obesity can impair the body's natural circadian rhythms, particularly in the cardiovascular system. The study suggests that this disruption can lead to a range of health problems, including impaired heart function and an increased risk of disease.
A new two-drug combination of phentermine and topiramate achieves more than double the weight loss of orlistat and compares favorably with emerging drugs. The treatment also improves blood pressure, lipids, glycaemia, and inflammatory markers.
In a one-year clinical trial, an investigational combination of drugs achieved unprecedented weight loss of up to 10 percent in obese individuals. The study found significant reductions in blood pressure, hemoglobin A1C, and inflammatory markers, as well as improvements in cholesterol and triglycerides.
A video-based decision aid helped patients weigh the pros and cons of bariatric surgery, leading to greater certainty and less conflict. The trial found that patients who watched the video felt more informed and confident in their decisions.
Scientists will present their work on reversing the obesity epidemic by understanding its molecular underpinnings. The conference will feature talks on emerging research, treatment options, and the impact of obesity on various bodily systems.
Researchers discovered that the flavonoid Nobiletin in tangerines prevents obesity and protects against metabolic syndrome, type 2 diabetes, and atherosclerosis. Nobiletin stimulated genes involved in burning excess fat and inhibited those responsible for manufacturing fat, leading to improved insulin sensitivity.
A nutrient sensing pathway has been identified as responsible for disrupting cellular lipid homeostasis in obese and insulin-resistant mice. This discovery may lead to the development of new drugs to slow or stop diabetes progression, as well as improve current treatments.
Women who are obese during early pregnancy have a significantly increased risk of their baby dying before, during or up to one year after birth. Obesity also increases the risk of complications such as bleeding and infections during and after a hysterectomy operation.
A new risk calculator predicts postoperative complications for individual bariatric surgery patients, helping surgeons and patients discuss risks before procedure. The tool aids in surgical decision-making and prepares patients for recovery.
A recent study published in the American Association for Cancer Research found that smoking did not affect breast cancer risk among obese postmenopausal women. In contrast, non-obese women with a history of smoking had a significantly higher risk for breast cancer.
New data show that NAFLD prevalence in the US is expected to increase by 50% by 2030, driven by rising obesity and diabetes rates. The condition can progress to advanced liver disease, significantly impacting mortality rates.
Researchers found that eating high amounts of protein made men who were trying to lose weight feel fuller throughout the day. The study also showed that larger meals led to reductions in appetite and feelings of fullness, contrary to the common trend of eating smaller, more frequent meals.
A Michigan State University researcher has been awarded a $3.3 million grant to develop an intervention program for low-income mothers who are overweight or obese. The program aims to promote healthy eating, physical activity and stress management through interactive DVDs and peer support.
Bariatric surgery has been shown to reduce the risk of heart attack and stroke in patients with diabetes, with 70% remission in two years and 30% remaining 15 years later. The surgery also reduces new cases of diabetes by 80% among obese patients.
Researchers found that increasing protein to 25% of total calories helps reduce late-night desires to eat and increases feelings of fullness. Lean cuts of pork are a high-protein food option that can be easily incorporated into daily meals.
A study published in The New England Journal of Medicine found that combining diet and exercise improves physical performance by 21% in obese seniors, compared to 12% with weight loss alone and 15% with exercise alone. This combination also leads to significant improvements in strength, balance, and quality of life.
A major UK study on anaesthesia complications shows obese patients are twice as likely to develop serious airway problems during a general anaesthetic. Routine monitoring of breathing with a capnograph could significantly reduce deaths and brain damage from such problems in intensive care units.
Researchers found that headache frequency and severity decreased substantially after bariatric surgery, with nearly half of patients experiencing at least a 50% reduction in migraine frequency. Weight loss also led to significant improvements in disability related to migraines.
A cross-cultural study found negative attitudes toward fat bodies in every location surveyed, revealing a rapid 'globalization of fat stigma' and a shift away from traditional fat-positive values. The study suggests that newer forms of media and public health campaigns may be driving this change.
Obese postmenopausal women are almost as likely to fracture as non-obese women, with specific sites like the upper arm, ankle, and lower leg being more prone to fractures in obese individuals. Poor mobility and a history of early menopause also play significant roles.
A study of Yup'ik Eskimos found that high intake of omega-3 fats from fish reduces markers of chronic disease risk in overweight/obese people. Obesity did not increase inflammation and blood triglycerides among participants with high blood levels of omega-3 fats.
A new study found that normal-weight young adults who frequently attend religious activities are 50% more likely to become obese by middle age. This association holds even after adjusting for demographic factors such as age, race, and education level.
Researchers from North America and Europe will present new osteoarthritis research at the Segal North American Osteoarthritis Workshop (SNOW) on March 25-27. The workshop aims to identify priority interventions that could improve treatment options for OA.
Researchers found that heavier individuals have wider femur shafts, hypothesizing this is due to increased weight and altered movement patterns. The study used 121 white male bones to eliminate racial and gender variations.
A study of 82 patients found gastric banding resulted in a mean excess weight loss of 42.8%, with 40% experiencing major complications and nearly half requiring band removal, despite a 60.3% patient satisfaction rate.
A Monash University study has found a direct link between time lived with obesity and the risk of mortality. Participants who experienced medium to long durations of obesity had significantly higher mortality rates compared to those who were never obese.
A daily dose of safflower oil improved health measures such as good cholesterol, blood sugar, and inflammation in obese postmenopausal women with Type 2 diabetes. The researchers found a significant association between safflower oil supplementation and reduced cardiovascular disease risk.
A study of nearly 800 severely mentally ill patients found two-thirds were overweight or obese, and a disproportionate number suffered from diabetes, heart disease, high blood pressure, and raised cholesterol. Life expectancy for these patients is reduced by up to 25 years, with cardiovascular disease being the major cause of death.
Researchers found that levels of five amino acids, including isoleucine and leucine, can signal future disease risk and indicate candidates for preventive measures. The study used metabolite measurements to identify individuals at elevated risk of developing type 2 diabetes.
Life expectancy is increasing in the UK and Europe, driven by declines in cardiovascular disease deaths. However, the East-West gap remains entrenched, and many questions about the drivers of these trends remain unanswered.
Researchers from Boston University School of Medicine found that African-American women who live in more densely populated urban areas tend to gain less weight over a six-year period. The study, which analyzed data from the Black Women's Health Study, suggests that policies promoting denser and urban residential development may help ad...
An international study of 220,000 people found that obese individuals with central obesity have a similar risk of heart attacks and strokes as those with general obesity, challenging earlier research. The study highlights the importance of measuring blood cholesterol and blood pressure levels in primary prevention.
Researchers at the University of Edinburgh have identified a protein that plays a key role in storing fat in the body. The study found that mice with high levels of this protein were more prone to developing unhealthy fat tissue after a high-fat diet, highlighting its potential as a target for obesity treatment.
A Chinese study found that individuals with a body mass index (BMI) of 24-25.9 had the lowest risk of death. This contradicts the current definitions of overweight and obesity in white populations, where BMI 22.5-24.9 is considered the lowest risk range.
Researchers at Harvard School of Dental Medicine found that blocking the Klotho protein function in obese mice with high blood sugar levels led to lean mice with reduced blood sugar levels. Additionally, mice without Klotho function gained no body weight after eating a high-fat diet.
Researchers identified a 'diabetes belt' of 644 counties in 15 southeastern states with high prevalence rates, linked to sedentary lifestyle, obesity, and non-modifiable factors. Community design changes can promote physical activity and healthy lifestyles to reduce diabetes risk.
A study of 143 overweight adolescents found those with risk factors like insulin resistance and low HDL cholesterol have less bone mass than their peers. The study suggests that increasing vigorous physical activity can help improve bone mass and reduce the risk of diabetes and heart disease.
A study funded by a $700,000 grant from the National Trauma Institute aims to improve blood-clot prevention medication dosing for critically ill or obese trauma patients. TEG technology will be used to guide physicians in determining the optimal dose of Lovenox.
A new study from Purdue University found that weight discrimination has a direct impact on the physical health of obese individuals, contributing to stress and declining functional abilities. Around 33% of severely obese people in the US report facing discriminatory experiences, which internalize prejudice and stigma.
A study published in Social Psychology Quarterly found that weight discrimination contributes to stress and a decline in functional abilities among severely obese individuals. Around a third of those who are severely obese report facing discriminatory experiences.
Researchers at the University of Pennsylvania identified the neurological and cellular signaling mechanisms that contribute to satiety and body-weight loss. They found that GLP-1 drugs target the nucleus tractus solitarius, which regulates food intake suppression.
Researchers found lower potassium levels associated with higher diabetes risk in African-Americans, who are twice as likely to develop type 2 diabetes. Increasing potassium levels through diet or supplements could potentially prevent the most common form of diabetes.
A study found that binge eaters experience a spike in dopamine levels when exposed to their favorite foods, triggering a desire for more. This neurological response is distinct from other obese individuals who do not exhibit this reaction.
A recent study found that lifestyle intervention, including nutrition and physical activity components, is necessary to maintain or lose weight. Clinicians can effectively prevent further weight gain by providing guidance on healthy habits, leading to improved health status in overweight patients.
Researchers developed an intervention to help pregnant women control their weight, with normal-weight women more likely to stay at a healthy weight. The program increased the chance of returning to pre-pregnancy weight six months after delivery, but had limited success for obese or overweight women during pregnancy.
A new genetic discovery suggests that the loss of function in a human-specific gene called CMAH may contribute to the development of Type 2 diabetes. The study found that mice with this gene mutation developed insulin resistance and pancreatic beta cell failure, leading to decreased insulin production and impaired blood glucose control.
A large proportion of Asians are underweight, but research found that those with a BMI in the range of 22.6 to 27.5 had the lowest risk of death, while severely underweight individuals were more than twice as likely to die.
Researchers found that obese individuals with early-onset knee osteoarthritis who underwent weight loss via bariatric surgery experienced significant improvements in knee pain, stiffness, and physical function. Weight loss also improved quality of life and activities of daily living.
A recent study published by Hospital for Special Surgery found that knee replacement surgeries take significantly longer and cost more for overweight patients. The researchers analyzed data from 454 patients and found that as body mass index increased, so did the time it took to perform all parts of the surgery.
Patients who undergo elective orthopedic surgeries at high-volume hospitals have better surgical outcomes and fewer complications than those at local hospitals. Regionalizers, or patients traveling to regional high-volume hospitals, tend to be younger, white, male, and have private insurance.
A study published in Annals of Internal Medicine found that obesity and knee osteoarthritis result in the loss of approximately 86 million healthy years of life among US adults aged 50-84. This loss disproportionately affects Black and Hispanic women, highlighting the need for targeted interventions to address these conditions.
New research reveals obesity significantly impacts knee pain and function, but also improves with weight loss via bariatric surgery. Studies find increased risk of complications after hip and knee replacement surgery for super-obese patients, emphasizing the importance of weight management in treating knee arthritis.
Researchers found that obesity reduces duration and quality of life by 12 percent, while knee osteoarthritis has a similar impact. A new guideline also recommends targeted prevention and treatment strategies for patients with specific characteristics, such as age, race, and functional status.
A study of 3,939 participants found that obesity was associated with higher eye pressure and a lower risk of open-angle glaucoma in women. The authors suggest that high estrogen levels and hormone therapy may be protective against open-angle glaucoma in obese women.