Articles tagged with Obesity
A new study published in The Journal of Physiology found that short-term high-intensity interval training (HIT) can be an effective alternative to traditional long-term exercise. By incorporating brief bursts of intense exercise, individuals can improve muscle function and burn fat without needing extensive exercise time.
Researchers discovered mitochondrial protein and gene anomalies in young obese subjects with type 2 diabetes, leading to insulin resistance and reduced physical exercise response. The study highlights the need for specific treatments for each patient subtype.
The new center, ORBIT, focuses on reducing obesity and its related risks through behavioral changes and mindful eating strategies. The team will develop personalized programs for community members in Harlem and the South Bronx.
A Kansas State University study found that the availability of supermarkets, rather than their lack, increases the risk of obesity for low-income women living in small cities. The researchers used a statewide dataset and found that micropolitan areas with higher supermarket availability had an increased risk of obesity.
A study published in Clinical Cancer Research found that obesity is a significant risk factor for poorer overall survival and death in patients with stage II or III colon cancer. Men with higher body mass indexes had a 35% increased risk of death compared to normal-weight patients.
According to Roger Unger, obesity is the body's way of storing lipids in fat tissue to protect other organs. This protective mechanism fails when the body's fat tissue can't handle excess calories, leading to metabolic syndrome. The rise of leptin resistance also plays a key role in this process.
Research suggests that moderate alcohol consumption may be associated with a lower risk of becoming overweight or obese. Women who drank less than 40 grams per day had the lowest risk, which was almost 30% lower than that of non-drinkers. This finding contradicts previous research and warrants further investigation.
A new study found that obesity is associated with a higher risk of developing colorectal tumors lacking microsatellite instability. The study also revealed that the relationship between body mass index and adult weight gain differs for tumors with varying levels of MSI.
A recent study by Wake Forest University School of Medicine found that both too little and excessive sleep can be hazardous to health, especially for young minority women. Short sleep duration of five hours or less per night was associated with large increases in visceral fat around organs.
A University of Alberta researcher has identified a way to lower the amount of fat in the blood and improve glucose metabolism. The study found that decreasing the activity of an enzyme called triacylglycerol hydrolase (TGH) can also protect against diabetes and increase physical activity.
A new University of Illinois study shows that soluble fiber can strengthen the immune system and reduce inflammation. The research found that mice fed soluble fiber were less sick and recovered faster from illness compared to those fed insoluble fiber.
A meta-analysis of 15 studies reveals a strong bidirectional association between obesity and depression, with obese individuals having a 55% increased risk of developing depression over time. The authors suggest that monitoring weight gain in depressive patients and mood in overweight or obese patients could lead to prevention, early d...
A new study from Johns Hopkins Medicine reveals that obesity in all forms increases the risk of developing kidney stones. The researchers found that obese individuals had a higher incidence of kidney stones compared to non-obese individuals, with no difference in risk between mild and severe obesity.
A new study found that critically ill patients with H1N1 influenza do not need increased Tamiflu dosages, contrary to international guidelines. The study showed that the 75 mg twice daily dosage of Tamiflu was well absorbed in these patients.
A Canadian Medical Association Journal article calls for legislative measures to address the growing epidemic of obesity, diabetes, and cardiovascular disease. The authors propose taxes on high-calorie foods, physical activity incentives, and advertising restrictions to encourage healthier habits among children.
The study aims to better understand the cause, diagnosis, and history of preeclampsia and diabetes in pregnant women, particularly those with hypertension or obesity. Researchers hope to develop effective treatments and therapies to save lives, reducing maternal mortality and complications.
Researchers at University of Cincinnati identify p62 and ERK as a critical protein duo involved in adipogenesis. The study shows how the interplay between these proteins leads to uncontrolled ERK activity, highlighting ERK as a promising target for obesity therapies.
Researchers found that pre-pregnancy obesity increases risk of medically-indicated preterm birth, while underweight also raises the risk. Optimal pregnancy weight gain within recommended guidelines reduces preterm birth risk in obese women.
Laparoscopic adjustable gastric banding surgery may be a better alternative to gastric bypass surgery for treating obesity in teens. While studies show greater weight loss with the bands, complication rates and cost-effectiveness remain concerns.
A Monash University-led nationwide study found that severely obese individuals feel powerless to change their weight due to internalized stigma and shame. In contrast, mildly to moderately obese individuals believed they could lose weight if needed, but felt no urgent need to do so.
Researchers at Gladstone Institute of Cardiovascular Disease discovered that DGAT1, an enzyme involved in fat storage, protects against diet-induced inflammation and insulin resistance. Enhancing DGAT1's capacity in macrophages may hold therapeutic promise for preventing obesity-related diseases.
Researchers found that obese patients with pancreatic cancer have significantly higher levels of MCP-1, a chemokine associated with inflammation, compared to non-obese patients with the same condition. Inflammation has been shown to contribute to tumor progression in pancreatic ductal adenocarcinoma.
About 5 million women in the US suffer from polycystic ovary syndrome (PCOS), a metabolic disorder causing infertility and obesity. Women are often told they are too fat, leading to delayed diagnoses, expert Andrea Dunaif advocates for increased awareness and treatment.
Researchers at Trinity College Dublin have made significant discoveries about Type 2 diabetes in young adults, shedding light on muscle cell mechanisms that contribute to severe insulin resistance. The study's findings may lead to the development of more targeted treatments for young people with Type 2 diabetes.
A study by University of Cincinnati researchers found that proapoptotic peptide treatment reduced food intake and fat loss in obese mice and rats, without affecting energy expenditure. The findings suggest a novel system informing brain activity about fat tissue size, influencing appetite and weight regulation.
Adults aged 70 and older who are classified as overweight are less likely to die over a 10-year period compared to those with a normal weight. The study found a reduced mortality risk by 13% among overweight participants, but only up to a certain point of obesity.
Researchers found that combining diet, exercise, and weight loss counseling can significantly reduce blood pressure and improve cardiovascular health. Additionally, low-carb diets may be as effective as medications in promoting weight loss and lowering blood pressure.
A new study published in Stroke: Journal of the American Heart Association found that a higher degree of obesity increases the risk of stroke, regardless of race, gender, or how obesity is measured. The study analyzed data from 13,549 middle-aged men and women and found significant disparities in stroke rates between whites and blacks.
Research at the University of California, San Diego, reveals that obesity is a tumor-promoting factor for liver cancer, primarily through chronic inflammation caused by cytokines like IL-6 and TNF. This effect may be preventable with anti-TNF drugs, which also reduce liver fat accumulation.
A computerized model estimates that most morbidly obese individuals would live longer if they had gastric bypass surgery. The model suggests younger patients with higher BMIs tend to gain more life expectancy from the procedure.
A recent study suggests that parks and recreation programs are declining in the US due to budget shortfalls, which may exacerbate the country's growing obesity epidemic. The research highlights the importance of access to recreational opportunities for addressing health issues related to overweight and obese individuals.
Recent IOM guidelines recommend obese women gain more weight, contradicting research that shows higher BMI levels are associated with severe medical conditions. Obese pregnant women can safely limit weight gain through a nutrient-rich diet and physical activity under doctor guidance.
Researchers have identified a molecular mechanism that controls energy expenditure in muscles and helps determine body weight. This discovery could lead to a new medical approach in treating obesity by targeting the ATP-sensitive potassium channel function in muscle tissue.
Researchers calculate that QALYs lost due to obesity are now equal to those lost due to smoking, both modifiable risk factors. This increase in burden is attributed to the growing proportion of obese individuals, which resulted in 0.0464 QALYs lost per population.
A new study reveals how the ATP-sensitive potassium channel affects food intake and energy balance, pointing to a potential pathway for managing and preventing obesity. Disrupting the channel's function in mice led to reduced fat deposition and increased energy efficiency, but also impaired endurance.
Researchers suggest that compulsive eating may be a legitimate addiction, sparking a new perspective on weight management. The concept of food addiction shares similarities with other addictive behaviors, including tolerance and withdrawal symptoms.
A study found that negative emotions associated with exercise in health clubs are stronger for overweight individuals than intellectual facts, controlling their regular exercise. Exercise professionals can help by minimizing intimidation and promoting the benefits of exercise to personal health and wellbeing.
Scientists have discovered that certain food aromas can contribute to feelings of fullness, potentially helping to combat obesity. By analyzing the effects of aroma release during chewing, researchers found that these scents can signal areas of the brain responsible for satiety, leading to reduced food intake.
A randomized controlled trial of 36 adults found that reducing TV time by half increased energy expenditure and burned 119 more calories per day. While calorie intake remained unchanged, this intervention suggests that adults may respond differently to reductions in sedentary behaviors compared to children.
A newly discovered gene called Brd2 has been found to play a crucial role in regulating body energy balance and protecting against Type 2 diabetes. In mice with a reduced expression of the Brd2 gene, obesity did not lead to diabetes, highlighting the importance of inflammation in this process.
The number of people overweight/obese increased significantly in sub-Saharan Africa between the early 1990s and early 2000s. The rate of increase was higher among the poor group, highlighting a pressing public health concern.
A two-year study found that moderate weight loss improved four key measures of heart health in obese patients, including decreased heart muscle thickness and improved pumping functions. After weight regain, some cardiovascular benefits were retained.
Research found moderate to heavy alcohol consumption increased breast cancer recurrence risk by 1.3-fold, with wine being the most popular choice among drinkers. Postmenopausal and overweight participants were more susceptible to the effects of alcohol on recurrence.
The NIH is launching a $37 million program to develop more effective interventions to reduce obesity by applying findings from basic behavioral and social sciences. The program will fund interdisciplinary teams conducting experimental research, formative studies, and pilot trials to identify promising new approaches.
A new study by the Kaiser Permanente Division of Research found that moderate alcohol consumption is associated with a 30% increased risk of breast cancer recurrence. Post-menopausal and overweight women may be most susceptible, regardless of type of alcohol consumed.
A large prospective study of over 20,000 Dutch men and women aged 20-65 found that accurately measured BMI and waist circumference can predict the risk of fatal and non-fatal cardiovascular disease. The associations between BMI and waist circumference with heart disease were equally strong, explaining half of all fatal and one quarter ...
Researchers found that college football linemen are at risk of obesity, insulin resistance, and metabolic syndrome due to their high body fat percentage. The study suggests that athletes concerned about maintaining a large size should prioritize healthy weight management and nutrition strategies.
Recent studies in fruit flies have identified a nuclear receptor that plays a critical role in regulating cholesterol levels, similar to humans. The findings suggest that fruit flies can teach humans about their own regulatory mechanisms for maintaining proper balances of cholesterol and stored fat.
A study by University of Michigan and Harvard researchers found that despite declines in smoking rates, the US population is experiencing a rise in obesity, which is overtaking the health benefits gained from quitting smoking. The study suggests that if current trends continue, nearly half of the population will be obese by 2020.
A retrospective study found that 52.1% of overweight adolescents had spine abnormalities, with most occurring within the discs. The study suggests a strong relationship between increased BMI in children and the incidence of lumbar disc disease.
A new study suggests that highly palatable, energy-dense foods can lead to increased fat storage by activating genes. Researchers found that a diet high in fat and sugar stimulates the kappa opioid receptor, causing the body to hold onto more fat than usual.
The number of Americans living with diabetes will nearly double from 23.7 million in 2009 to 44.1 million in 2034, and spending on diabetes will almost triple, rising from $113 billion to $336 billion. This growth is expected to add a significant strain to the healthcare system.
A new study by a European research team has found that obese people have high levels of the molecule CXCL5, produced by fatty tissue cells. This discovery could lead to an experimental treatment aimed at inhibiting the action of CXCL5 to protect against type 2 diabetes.
A recent study by Loyola University Health System found that one out of five adults with Type 2 diabetes is morbidly obese. The rate of morbid obesity among people with diabetes increased by 141% between 1976 and 2006, highlighting the growing public health implications.
A consensus statement on diabetes surgery recognizes the legitimacy of surgery as a dedicated treatment for type 2 diabetes in carefully selected patients. The document summarizes evidence showing that bariatric surgery effectively reverses type 2 diabetes, and its findings justify considering surgery as a specific diabetes intervention.
A study at Henry Ford Hospital found that robotic surgery is effective in removing uterine fibroids regardless of patient weight. Obesity was not shown to be a risk factor for poor surgical outcome, contradicting previous concerns.
Tufts University researchers identified a gene-diet interaction linked to body weight and obesity, replicated in three independent studies. Men with the CC genotype consuming high-saturated fat diets showed higher BMI scores and obesity risk compared to those with low-saturated fat intake or other genotypes.
A study found that the average BMI of adult Americans increased from 26.5 to 28.8 kg/m2, undermining progress in reducing blood pressure and fasting glucose risk factors. Despite public health efforts, there is no net improvement in the overall cardiovascular risk factor profile.
Research found that 8% of obese individuals perceive themselves as satisfied with their body size or believe they can gain weight. These misperceptions are associated with a higher risk of chronic diseases and lower likelihood of seeking medical care.
Research suggests that active Wii sports and Wii fit activities can increase energy expenditure to levels comparable to moderately intense exercise. The study found that some activities, such as boxing and single-arm stand, require high energy expenditures of up to 5.6 METs.